As ethnic medicine,the whole grass of plants in Cirsium was used as antimicrobial.This review focuses on the antimicrobial activity of plants in Cirsium,including antimicrobial components,against different types of mi...As ethnic medicine,the whole grass of plants in Cirsium was used as antimicrobial.This review focuses on the antimicrobial activity of plants in Cirsium,including antimicrobial components,against different types of microbes and bacteriostatic mechanism.The results showed that the main antimicrobial activity components in Cirsium plants were flavonoids,triterpenoids and phenolic acids,and the antimicrobial ability varied according to the species and the content of chemicals.Among them,phenolic acids showed a strong antibacterial ability against Acinetobacter baumannii,Pseudomonas aeruginosa,and Enterococcus faecium.The antibacterial mechanisms include:(1)damaging the cell membrane,cell walls,mitochondria and nucleus of bacteria;(2)inhibiting the synthesis of proteins and nucleic acids;(3)suppressing the synthesis of enzymes for tricarboxylic acid cycle pathways and glycolysis,and then killing the bacteria via inhibition of energy production.Totally,most research results on antimicrobial activity of Cirsium plants are reported based on in vitro assays.The evidence from clinical data and comprehensive evaluation are needed.展开更多
Pulp capping is one of the solving for keeping vital pulp in the case of dentin caries,reversible pulpitis or traumatic pulp exposure.The presence of bacteria on the cavity walls or in the pulp was the major factor th...Pulp capping is one of the solving for keeping vital pulp in the case of dentin caries,reversible pulpitis or traumatic pulp exposure.The presence of bacteria on the cavity walls or in the pulp was the major factor that leads to the failure of pulp capping.Traditional pulp capping agent,calcium hydroxide,may not prevent microleakage.Selfetching system is a newly developed adhesive system,which could provide less microleakage and would not break down or dissolve,preventing the oral fluids and bacteria from the pulp along the cavity wall.This may reduce such clinical problems as postoperative sensitivity,secondary caries and marginal discoloration.Researches showed that some kinds of self-etching adhesives induced the mild to moderate inflammatory pulp response,with negative bacterial staining.Inclusion of antibacterial components into self-etching system,such as 12-methacryloyloxydodecylpyridinium bromide(MDPB)may inhibit bacteria and provide better clinical effects.It is speculated that using the self-etching adhesive system containing the antibacterial agent,such as MDPB,to the dental pulp directly or indirectly,may inhibit bacteria after the placement of restoration as well as residual bacteria in the cavity.展开更多
文摘As ethnic medicine,the whole grass of plants in Cirsium was used as antimicrobial.This review focuses on the antimicrobial activity of plants in Cirsium,including antimicrobial components,against different types of microbes and bacteriostatic mechanism.The results showed that the main antimicrobial activity components in Cirsium plants were flavonoids,triterpenoids and phenolic acids,and the antimicrobial ability varied according to the species and the content of chemicals.Among them,phenolic acids showed a strong antibacterial ability against Acinetobacter baumannii,Pseudomonas aeruginosa,and Enterococcus faecium.The antibacterial mechanisms include:(1)damaging the cell membrane,cell walls,mitochondria and nucleus of bacteria;(2)inhibiting the synthesis of proteins and nucleic acids;(3)suppressing the synthesis of enzymes for tricarboxylic acid cycle pathways and glycolysis,and then killing the bacteria via inhibition of energy production.Totally,most research results on antimicrobial activity of Cirsium plants are reported based on in vitro assays.The evidence from clinical data and comprehensive evaluation are needed.
文摘Pulp capping is one of the solving for keeping vital pulp in the case of dentin caries,reversible pulpitis or traumatic pulp exposure.The presence of bacteria on the cavity walls or in the pulp was the major factor that leads to the failure of pulp capping.Traditional pulp capping agent,calcium hydroxide,may not prevent microleakage.Selfetching system is a newly developed adhesive system,which could provide less microleakage and would not break down or dissolve,preventing the oral fluids and bacteria from the pulp along the cavity wall.This may reduce such clinical problems as postoperative sensitivity,secondary caries and marginal discoloration.Researches showed that some kinds of self-etching adhesives induced the mild to moderate inflammatory pulp response,with negative bacterial staining.Inclusion of antibacterial components into self-etching system,such as 12-methacryloyloxydodecylpyridinium bromide(MDPB)may inhibit bacteria and provide better clinical effects.It is speculated that using the self-etching adhesive system containing the antibacterial agent,such as MDPB,to the dental pulp directly or indirectly,may inhibit bacteria after the placement of restoration as well as residual bacteria in the cavity.
