AIM： To evaluate the antifertility activity of Artemisia vulgar＆ leaves on female Wistar rats. METHOD： The plant extract was tested for its effect on implant formation at two dose levels, 300 and 600 mg.kg 1, respe...AIM： To evaluate the antifertility activity of Artemisia vulgar＆ leaves on female Wistar rats. METHOD： The plant extract was tested for its effect on implant formation at two dose levels, 300 and 600 mg.kg 1, respectively. The effective methanolic plant extract was further studied for estrogenic potency on ovariectomised immature female Wistar rats. RESULTS： The data presented in this study demonstrate the antifertility potential of Artemisia vulgar＆ methanolic leaf extract, which shows a strong and significant decrease in implant formation （100%）, and a strong estrogenic effect resulting in a significant increase in uterine weight in immature ovariectomised rats. These observations suggest that the methanolic extract of Artemisia vulgaris leaves has strong anti-implantation activity and estrogenic activity. CONCLUSION： The methanolic plant extract ofA. vulgaris has antifertility activity.展开更多
基金Dr. Ravindra Reddy,Principal,P. Ramireddy Memorial College of Pharmacy for providing all the necessary assistance required for this study and also his moral support
文摘AIM： To evaluate the antifertility activity of Artemisia vulgar＆ leaves on female Wistar rats. METHOD： The plant extract was tested for its effect on implant formation at two dose levels, 300 and 600 mg.kg 1, respectively. The effective methanolic plant extract was further studied for estrogenic potency on ovariectomised immature female Wistar rats. RESULTS： The data presented in this study demonstrate the antifertility potential of Artemisia vulgar＆ methanolic leaf extract, which shows a strong and significant decrease in implant formation （100%）, and a strong estrogenic effect resulting in a significant increase in uterine weight in immature ovariectomised rats. These observations suggest that the methanolic extract of Artemisia vulgaris leaves has strong anti-implantation activity and estrogenic activity. CONCLUSION： The methanolic plant extract ofA. vulgaris has antifertility activity.
