G_9315 was a complex extracted from glycyrrhizae inflata Bat (Ⅲ) and consisted of 6 flavonoids with significant antioxidant effects.At 1 mg dose it inhibited the mouse ear edema induced by croton oil, and it showed s...G_9315 was a complex extracted from glycyrrhizae inflata Bat (Ⅲ) and consisted of 6 flavonoids with significant antioxidant effects.At 1 mg dose it inhibited the mouse ear edema induced by croton oil, and it showed strong antipromoting effect on two stage carcinogenesis in mouse skin induced by DMBA plus croton oil.The TPA enhanced 32Pi-incorporation into phospholipid fraction in HeLa cells and the micronuclei in mouse bone marrow induced by cytoxan was inhibited.The lipid peroxidation of polymorphonuclear leukocytes (PMN) of Wistar rats and the mouse liver microsome and mitochondria induced by croton oil were also depressed by it.展开更多
文摘G_9315 was a complex extracted from glycyrrhizae inflata Bat (Ⅲ) and consisted of 6 flavonoids with significant antioxidant effects.At 1 mg dose it inhibited the mouse ear edema induced by croton oil, and it showed strong antipromoting effect on two stage carcinogenesis in mouse skin induced by DMBA plus croton oil.The TPA enhanced 32Pi-incorporation into phospholipid fraction in HeLa cells and the micronuclei in mouse bone marrow induced by cytoxan was inhibited.The lipid peroxidation of polymorphonuclear leukocytes (PMN) of Wistar rats and the mouse liver microsome and mitochondria induced by croton oil were also depressed by it.
