It is hypothesized that betaine supplementation improves production performance in mid-lactation dairy cows.Twenty-one mid-lactation dairy cows were assigned to a 3×3 Latin square design with three periods of 28 ...It is hypothesized that betaine supplementation improves production performance in mid-lactation dairy cows.Twenty-one mid-lactation dairy cows were assigned to a 3×3 Latin square design with three periods of 28 d each and fed three treatments of betaine(0,100,and 200 g/d).Milk samples were collected on day 21 and day 28 of each period.During days 21 to 28,cows were fed with chromic oxide(15 g/d per cow).On days 26 to 28,fecal samples were collected to determine apparent total tract nutrient digestion.Blood samples were obtained on days 26 to 28 of each period for fatty acid(FA)analysis.Data were analyzed using the Proc Mixed in SAS.Apparent total tract dry matter(DM)digestibility tended to be greater for cows supplemented with 100 g betaine as compared to no dietary betaine(61 vs.58±1%;p=0.1).In contrast,DM intake(DMI),milk fat percent,milk yield,energy-corrected milk(ECM)yield,and milk FA composition did not differ among treatments.Supplementation of betaine can decrease the serum saturated FA C11,C12,C15 and C17,total monounsaturated FA,and C18:2 all trans-9,12.In addition,total serum n-3 polyunsaturated FA was significantly increased.This result can decrease total serum n-6 to n-3 ratio(6.80,7.07,and 6.50±0.16%,for 0,100,and 200 g betaine,respectively;p=0.04).Overall,even betaine supplementation did not change DMI or production,betaine could affect the DM digestibility and serum FA biosynthesis.展开更多
Totally implantable access port is a fully implantable drug delivery system that is implanted subcutaneously and can be retained for a long time.Advantages of ports include a simple nursing process,low risk of infecti...Totally implantable access port is a fully implantable drug delivery system that is implanted subcutaneously and can be retained for a long time.Advantages of ports include a simple nursing process,low risk of infection and embolism,and high patient comfort.In order to promote the standardized application of ports in the treatment of digestive tract tumors and reduce port-related complications,the Chinese Research Hospital Association Digestive Tumor Committee,the Chinese Association of Upper Gastrointestinal Surgeons,the Chinese Gastric Cancer Association,and the Gastrointestinal Surgical Group of Chinese Surgical Society Affiliated to Chinese Medical Association have organized multidisciplinary expert discussions at the General Hospital of the People’s Liberation Army and nationwide expert letter reviews and on-site seminars,and formulated an expert consensus of the operation guidelines.展开更多
Background： This study aimed to determine the effect of the inclusion of corn gluten feed （CGF） on the apparent and standardized ileal digestibility of protein and amino acids and the apparent ileal and total tract...Background： This study aimed to determine the effect of the inclusion of corn gluten feed （CGF） on the apparent and standardized ileal digestibility of protein and amino acids and the apparent ileal and total tract digestibility of energy in growing pigs. The study was performed using 16 barrows （weight, 45.3 ±4.5 kg） that were fitted with a T cannula at the terminal ileum. There were four treatments： a corn-soybean diet without CGF and three corn-soybean diets containing increasing levels of CGF （65, 130, and 195 g/kg）. Data were analyzed according to a randomized complete block design, four blocks with four pigs each （one pig per treatment）. The trend of the response （linear or quadratic） was determined using orthogonal contrasts, and when a linear effect was determined, a linear equation was obtained. Results： The results showed that the inclusion up to 195 g/kg of CGF in the corn-soybean diet did not diminish the ileal digestibility （apparent and standardized） of protein and amino acids （P 〉 0.05）, except that of phenylalanine, cystine, and proline. A linear decrease （P 〈 0.05） per gram of CGF added to the diet in the apparent and standardized ileal digestibility of phenylalanine （0.011 and 0.015 percentage units, respectively）, cystine （0.048 and 0.043 percentage units, respectively）, and proline （0.045 and 0.047 percentage units, respectively） was noted. Similarly, ileal digestibility of dry matter and energy were adversely affected （reduced by 0.028 and 0.025 percentage units, respectively, per gram of CGF increment in the diet）. A significant （P 〈 0.05） linear reduction in total tract digestibility with increase in CGF amount in the diet was observed for energy （0.027 percentage units）, dry matter （0.027 percentage units）, crude protein （0.020 percentage units）, and neutral detergent fiber （0.041 percentage units） per gram of CGF added to the diet. Conclusion： CGF did not affect the ileal digestibility of protein and most amino acids but reduced the ileal and total tract digestibility of energy.展开更多
AIM:To evaluate the safety and feasibility of a modified delta-shaped gastroduodenostomy(DSG)in totally laparoscopic distal gastrectomy(TLDG).METHODS:We performed a case-control study enrolling 63 patients with distal...AIM:To evaluate the safety and feasibility of a modified delta-shaped gastroduodenostomy(DSG)in totally laparoscopic distal gastrectomy(TLDG).METHODS:We performed a case-control study enrolling 63 patients with distal gastric cancer(GC)undergoing TLDG with a DSG from January 2013 to June 2013.Twenty-two patients underwent a conventional DSG(Con-Group),whereas the other 41 patients underwent a modified version of the DSG(Mod-Group).The modified procedure required only the instruments of the surgeon and assistant to complete the involution of the common stab incision and to completely resect the duodenal cutting edge,resulting in an anastomosis with an inverted T-shaped appearance.The clinicopathological characteristics,surgical outcomes,anastomosis time and complications of the two groups were retrospectively analyzed using a prospectively maintained comprehensive database.RESULTS:DSG procedures were successfully completed in all of the patients with histologically complete(R0)resections,and none of these patients required conversion to open surgery.The clinicopathological characteristics of the two groups were similar.There were no significant differences between the groups in the operative time,intraoperative blood loss,extension of the lymph node(LN)dissection and number of dissected LNs(150.8±21.6 min vs 143.4±23.4 min,P=0.225for the operative time;26.8±11.3 min vs 30.6±14.8mL,P=0.157 for the intraoperative blood loss;4/18 vs3/38,P=0.375 for the extension of the LN dissection;and 43.9±13.4 vs 39.5±11.5 per case,P=0.151 for the number of dissected LNs).The anastomosis time,however,was significantly shorter in the Mod-Group than in the Con-Group(13.9±2.8 min vs 23.9±5.6min,P=0.000).The postoperative outcomes,including the times to out-of-bed activities,first flatus,resumption of soft diet and postoperative hospital stay,as well as the anastomosis size,did not differ significantly(1.9±0.6 d vs 2.3±1.5 d,P=0.228 for the time to outof-bed activities;3.2±0.9 d vs 3.5±1.3 d,P=0.295for the first flatus time;7.5±0.8 d vs 8.1±4.3 d,P=0.489 for the resumption of a soft diet time;14.3±10.6 d vs 11.5±4.9 d,P=0.148 for the postoperative hospital stay;and 30.5±3.6 mm vs 30.1±4.0 mm,P=0.730 for the anastomosis size).One patient with minor anastomotic leakage in the Con-Group was managed conservatively;no other patients experienced any complications around the anastomosis.The operative complication rates were similar in the Con-and ModGroups(9.1%vs 7.3%,P=1.000).CONCLUSION:The modified DSG,an alternative reconstruction in TLDG for GC,is technically safe and feasible,with a simpler process that reduces the anastomosis time.展开更多
目的探讨行腹腔镜下右半结肠癌根治术患者消化道重建时使用倒刺线关闭共同开口及加固吻合口的有效性和安全性。方法选择2021年1月至2022年12月于河南省肿瘤医院行右半结肠癌根治术患者82例为研究对象。根据术中消化道重建方法将患者分...目的探讨行腹腔镜下右半结肠癌根治术患者消化道重建时使用倒刺线关闭共同开口及加固吻合口的有效性和安全性。方法选择2021年1月至2022年12月于河南省肿瘤医院行右半结肠癌根治术患者82例为研究对象。根据术中消化道重建方法将患者分为对照组(n=40)和观察组(n=42)。对照组患者术中使用直线切割闭合器关闭共同开口,吻合口不加固;观察组患者术中使用倒刺线关闭共同开口及加固吻合口。比较2组患者消化道重建时间、使用钉仓的数量、术中出血量等手术相关指标,比较2组患者术后排气时间、术后住院时间和手术前后24 h血红蛋白(Hb)差值;记录并比较2组患者术后并发症发生率。结果观察组患者消化道重建时间长于对照组,使用钉仓数少于对照组(P<0.05);2组患者术中出血量比较差异无统计学意义(P>0.05)。2组患者术后排气时间、术后住院时间比较差异无统计学意义(P>0.05)。观察组患者手术前后24 h Hb差值小于对照组(P<0.05)。对照组和观察组患者术后并发症发生率分别为7.1%(3/42)和12.5%(5/40),2组患者并发症发生率比较差异无统计学意义(χ^(2)=0.799,P>0.05)。结论使用倒刺线关闭共同开口及加固吻合口是一种安全、可行且止血效果较好的消化道重建方法。展开更多
文摘It is hypothesized that betaine supplementation improves production performance in mid-lactation dairy cows.Twenty-one mid-lactation dairy cows were assigned to a 3×3 Latin square design with three periods of 28 d each and fed three treatments of betaine(0,100,and 200 g/d).Milk samples were collected on day 21 and day 28 of each period.During days 21 to 28,cows were fed with chromic oxide(15 g/d per cow).On days 26 to 28,fecal samples were collected to determine apparent total tract nutrient digestion.Blood samples were obtained on days 26 to 28 of each period for fatty acid(FA)analysis.Data were analyzed using the Proc Mixed in SAS.Apparent total tract dry matter(DM)digestibility tended to be greater for cows supplemented with 100 g betaine as compared to no dietary betaine(61 vs.58±1%;p=0.1).In contrast,DM intake(DMI),milk fat percent,milk yield,energy-corrected milk(ECM)yield,and milk FA composition did not differ among treatments.Supplementation of betaine can decrease the serum saturated FA C11,C12,C15 and C17,total monounsaturated FA,and C18:2 all trans-9,12.In addition,total serum n-3 polyunsaturated FA was significantly increased.This result can decrease total serum n-6 to n-3 ratio(6.80,7.07,and 6.50±0.16%,for 0,100,and 200 g betaine,respectively;p=0.04).Overall,even betaine supplementation did not change DMI or production,betaine could affect the DM digestibility and serum FA biosynthesis.
基金Supported by Program of B.Braun Medical,No.CN-0486-AECVSE2019169Program of Military Medicine for Youth,No.QNF19055.
文摘Totally implantable access port is a fully implantable drug delivery system that is implanted subcutaneously and can be retained for a long time.Advantages of ports include a simple nursing process,low risk of infection and embolism,and high patient comfort.In order to promote the standardized application of ports in the treatment of digestive tract tumors and reduce port-related complications,the Chinese Research Hospital Association Digestive Tumor Committee,the Chinese Association of Upper Gastrointestinal Surgeons,the Chinese Gastric Cancer Association,and the Gastrointestinal Surgical Group of Chinese Surgical Society Affiliated to Chinese Medical Association have organized multidisciplinary expert discussions at the General Hospital of the People’s Liberation Army and nationwide expert letter reviews and on-site seminars,and formulated an expert consensus of the operation guidelines.
基金funded in part by the Ministry of Agriculture,Livestock and Fishing(SAGARPA) of Mexico and The National Council for Science and Technology(CONACYT) of Mexico via the financial support provided to Research Project SAGARPA-CONACYT 2003-2-169
文摘Background： This study aimed to determine the effect of the inclusion of corn gluten feed （CGF） on the apparent and standardized ileal digestibility of protein and amino acids and the apparent ileal and total tract digestibility of energy in growing pigs. The study was performed using 16 barrows （weight, 45.3 ±4.5 kg） that were fitted with a T cannula at the terminal ileum. There were four treatments： a corn-soybean diet without CGF and three corn-soybean diets containing increasing levels of CGF （65, 130, and 195 g/kg）. Data were analyzed according to a randomized complete block design, four blocks with four pigs each （one pig per treatment）. The trend of the response （linear or quadratic） was determined using orthogonal contrasts, and when a linear effect was determined, a linear equation was obtained. Results： The results showed that the inclusion up to 195 g/kg of CGF in the corn-soybean diet did not diminish the ileal digestibility （apparent and standardized） of protein and amino acids （P 〉 0.05）, except that of phenylalanine, cystine, and proline. A linear decrease （P 〈 0.05） per gram of CGF added to the diet in the apparent and standardized ileal digestibility of phenylalanine （0.011 and 0.015 percentage units, respectively）, cystine （0.048 and 0.043 percentage units, respectively）, and proline （0.045 and 0.047 percentage units, respectively） was noted. Similarly, ileal digestibility of dry matter and energy were adversely affected （reduced by 0.028 and 0.025 percentage units, respectively, per gram of CGF increment in the diet）. A significant （P 〈 0.05） linear reduction in total tract digestibility with increase in CGF amount in the diet was observed for energy （0.027 percentage units）, dry matter （0.027 percentage units）, crude protein （0.020 percentage units）, and neutral detergent fiber （0.041 percentage units） per gram of CGF added to the diet. Conclusion： CGF did not affect the ileal digestibility of protein and most amino acids but reduced the ileal and total tract digestibility of energy.
基金Supported by National Key Clinical Specialty Discipline Construction Program of China,No.(2012)649
文摘AIM:To evaluate the safety and feasibility of a modified delta-shaped gastroduodenostomy(DSG)in totally laparoscopic distal gastrectomy(TLDG).METHODS:We performed a case-control study enrolling 63 patients with distal gastric cancer(GC)undergoing TLDG with a DSG from January 2013 to June 2013.Twenty-two patients underwent a conventional DSG(Con-Group),whereas the other 41 patients underwent a modified version of the DSG(Mod-Group).The modified procedure required only the instruments of the surgeon and assistant to complete the involution of the common stab incision and to completely resect the duodenal cutting edge,resulting in an anastomosis with an inverted T-shaped appearance.The clinicopathological characteristics,surgical outcomes,anastomosis time and complications of the two groups were retrospectively analyzed using a prospectively maintained comprehensive database.RESULTS:DSG procedures were successfully completed in all of the patients with histologically complete(R0)resections,and none of these patients required conversion to open surgery.The clinicopathological characteristics of the two groups were similar.There were no significant differences between the groups in the operative time,intraoperative blood loss,extension of the lymph node(LN)dissection and number of dissected LNs(150.8±21.6 min vs 143.4±23.4 min,P=0.225for the operative time;26.8±11.3 min vs 30.6±14.8mL,P=0.157 for the intraoperative blood loss;4/18 vs3/38,P=0.375 for the extension of the LN dissection;and 43.9±13.4 vs 39.5±11.5 per case,P=0.151 for the number of dissected LNs).The anastomosis time,however,was significantly shorter in the Mod-Group than in the Con-Group(13.9±2.8 min vs 23.9±5.6min,P=0.000).The postoperative outcomes,including the times to out-of-bed activities,first flatus,resumption of soft diet and postoperative hospital stay,as well as the anastomosis size,did not differ significantly(1.9±0.6 d vs 2.3±1.5 d,P=0.228 for the time to outof-bed activities;3.2±0.9 d vs 3.5±1.3 d,P=0.295for the first flatus time;7.5±0.8 d vs 8.1±4.3 d,P=0.489 for the resumption of a soft diet time;14.3±10.6 d vs 11.5±4.9 d,P=0.148 for the postoperative hospital stay;and 30.5±3.6 mm vs 30.1±4.0 mm,P=0.730 for the anastomosis size).One patient with minor anastomotic leakage in the Con-Group was managed conservatively;no other patients experienced any complications around the anastomosis.The operative complication rates were similar in the Con-and ModGroups(9.1%vs 7.3%,P=1.000).CONCLUSION:The modified DSG,an alternative reconstruction in TLDG for GC,is technically safe and feasible,with a simpler process that reduces the anastomosis time.
文摘目的探讨行腹腔镜下右半结肠癌根治术患者消化道重建时使用倒刺线关闭共同开口及加固吻合口的有效性和安全性。方法选择2021年1月至2022年12月于河南省肿瘤医院行右半结肠癌根治术患者82例为研究对象。根据术中消化道重建方法将患者分为对照组(n=40)和观察组(n=42)。对照组患者术中使用直线切割闭合器关闭共同开口,吻合口不加固;观察组患者术中使用倒刺线关闭共同开口及加固吻合口。比较2组患者消化道重建时间、使用钉仓的数量、术中出血量等手术相关指标,比较2组患者术后排气时间、术后住院时间和手术前后24 h血红蛋白(Hb)差值;记录并比较2组患者术后并发症发生率。结果观察组患者消化道重建时间长于对照组,使用钉仓数少于对照组(P<0.05);2组患者术中出血量比较差异无统计学意义(P>0.05)。2组患者术后排气时间、术后住院时间比较差异无统计学意义(P>0.05)。观察组患者手术前后24 h Hb差值小于对照组(P<0.05)。对照组和观察组患者术后并发症发生率分别为7.1%(3/42)和12.5%(5/40),2组患者并发症发生率比较差异无统计学意义(χ^(2)=0.799,P>0.05)。结论使用倒刺线关闭共同开口及加固吻合口是一种安全、可行且止血效果较好的消化道重建方法。
