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Analysis of application range of simplified models for field to thermo-field to thermionic emission processes from the cathode
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作者 Li SUN Zhuo DAI +2 位作者 Ming XU Wei WANG Zengyao LI 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第9期51-60,共10页
Electron emission plays a dominant role in plasma-cathode interactions and is a key factor in many plasma phenomena and industrial applications.It is necessary to illustrate the various electron emission mechanisms an... Electron emission plays a dominant role in plasma-cathode interactions and is a key factor in many plasma phenomena and industrial applications.It is necessary to illustrate the various electron emission mechanisms and the corresponding applicable description models to evaluate their impacts on discharge properties.In this study,detailed expressions of the simplified formulas valid for field emission to thermo-field emission to thermionic emission typically used in the numerical simulation are proposed,and the corresponding application ranges are determined in the framework of the Murphy-Good theory,which is commonly regarded as the general model and to be accurate in the full range of conditions of the validity of the theory.Dimensionless parameterization was used to evaluate the emission current density of the Murphy-Good formula,and a deviation factor was defined to obtain the application ranges for different work functions(2.5‒5 eV),cathode temperatures(300‒6000 K),and emitted electric fields(10^(5) to 10^(10) V·m^(-1)).The deviation factor was shown to be a nonmonotonic function of the three parameters.A comparative study of particle number densities in atmospheric gas discharge with a tungsten cathode was performed based on the one-dimensional implicit particle-in-cell(PIC)with the Monte Carlo collision(MCC)method according to the aforementioned application ranges.It was found that small differences in emission current density can lead to variations in the distributions of particle number density due to changes in the collisional environment.This study provides a theoretical basis for selecting emission models for subsequent numerical simulations. 展开更多
关键词 electron emission processes application range Murphy-Good theory implicit particlein-cell Monte Carlo collision method
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The Development of the “Monitoring Application for Inappropriate Expressions in Nursing Records”for PsyNACS©
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作者 Hirokazu Ito Yuko Yasuhara Tetsuya Tanioka 《Journal of Computer and Communications》 2024年第5期42-52,共11页
Lengthening periods of hospitalization, increasing numbers of patients with age-related complications, and a shortage of nursing staff have been of great concern in medical psychiatry in Japan. Under these circumstanc... Lengthening periods of hospitalization, increasing numbers of patients with age-related complications, and a shortage of nursing staff have been of great concern in medical psychiatry in Japan. Under these circumstances, countries such as Japan that face a super-aging society and a decline in the working-age population, have been recommended for use of advanced information and communications technology (ICT) to improve the efficiency of medical treatment and care. This study aims to develop the “Monitoring Application for Inappropriate Expressions in Nursing Records” for using PsyNACS<sup>©</sup>, which will enable psychiatric nursing plans to harness the advantages of ICT. The functions considered necessary are as follows: 1) identification of users who enter information;2) a necessary database for lists of inappropriate expressions;3) development of a matching function to recommend proper writing input and a warning function;and 4) a management function for an inappropriate expression list database. A demonstration experiment for developing the application in this study was conducted at a specialized psychiatric hospital. To introduce them to the application, nurses and nurse managers were informed about the system developed in this study, and a survey regarding their opinions on the functions of the application was conducted with ten nurse managers. The results were evaluated in terms of usefulness for nursing care, documentation, and the education of nurses from an ethical perspective. This study suggests that matching their input with an inappropriate expression database will allow nurses to record more appropriate expressions. From an ethical perspective, the ability to use appropriate expressions makes records more likely to withstand disclosure requests from patients and their families. 展开更多
关键词 PsyNACS© Monitoring application Inappropriate Expressions Nursing Records
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Quality of Service and Security on Cisco Network Devices, Coupled with the Development of a Mobile Application Prototype Software for Server Room Temperature Monitoring
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作者 Desire Mudenda Charles Smart Lubobya 《Journal of Computer and Communications》 2024年第8期123-140,共18页
In an era where digital technology is paramount, higher education institutions like the University of Zambia (UNZA) are employing advanced computer networks to enhance their operational capacity and offer cutting-edge... In an era where digital technology is paramount, higher education institutions like the University of Zambia (UNZA) are employing advanced computer networks to enhance their operational capacity and offer cutting-edge services to their academic fraternity. Spanning across the Great East Road campus, UNZA has established one of the most extensive computer networks in Zambia, serving a burgeoning community of over 20,000 active users through a Metropolitan Area Network (MAN). However, as the digital landscape continues to evolve, it is besieged with burgeoning challenges that threaten the very fabric of network integrity—cyber security threats and the imperatives of maintaining high Quality of Service (QoS). In an effort to mitigate these threats and ensure network efficiency, the development of a mobile application to monitor temperatures in the server room was imperative. According to L. Wei, X. Zeng, and T. Shen, the use of wireless sensory networks to monitor the temperature of train switchgear contact points represents a cost-effective solution. The system is based on wireless communication technology and is detailed in their paper, “A wireless solution for train switchgear contact temperature monitoring and alarming system based on wireless communication technology”, published in the International Journal of Communications, Network and System Sciences, vol. 8, no. 4, pp. 79-87, 2015 [1]. Therefore, in this study, a mobile application technology was explored for monitoring of temperatures in the server room in order to aid Cisco device performance. Additionally, this paper also explores the hardening of Cisco device security and QoS which are the cornerstones of this study. 展开更多
关键词 Quality of Service (QoS) Network Security Temperature Monitoring Mobile application Cisco Devices
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Research on the Application of New Energy Photovoltaic Power Generation Technology
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作者 Weimin Liu Yue Qi 《Journal of Electronic Research and Application》 2024年第5期168-173,共6页
With the rapid development of technology and economy,the demand for energy in society is increasing.People are gradually realizing that fossil energy is limited,and the development of new energy may also face situatio... With the rapid development of technology and economy,the demand for energy in society is increasing.People are gradually realizing that fossil energy is limited,and the development of new energy may also face situations where it cannot meet social needs.The problem of resource shortage is gradually exposed to people.Therefore,the development of usable new energy has become an urgent problem for society to solve.At present,electricity is the most widely used energy source worldwide and photovoltaic power generation technology is gradually becoming well-known.As an emerging industry,the development of photovoltaic power generation still requires continuous promotion by national and social policies to be extended to various industries and ensure the stability of its energy supply.This article mainly outlines the principles,characteristics,and advantages of photovoltaic power generation,and briefly explains the current technology types and application aspects of photovoltaic power generation to contribute to its promotion and better serve all aspects of social life with new energy. 展开更多
关键词 New energy Photovoltaic power generation application
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Analysis of the Design and Application of a Novel CT Secondary Cable Line Calibrator
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作者 Jiaxing Ren 《Journal of Electronic Research and Application》 2024年第2期7-11,共5页
With the rapid development of electrical power systems,ensuring the accuracy and reliability of power transmis-sion has become particularly crucial.The secondary cable line calibrator for current transformers(CT)plays... With the rapid development of electrical power systems,ensuring the accuracy and reliability of power transmis-sion has become particularly crucial.The secondary cable line calibrator for current transformers(CT)plays an essential role in calibrating electrical power systems.It is not only related to the safe operation of the system but also directly im-pacts the accuracy of energy metering.This study aims to design and analyze an efficient CT secondary cable line calibra-tor to explore its application effects in the power system.By thoroughly analyzing the characteristics of CT secondary ca-ble lines and the design requirements of the calibrator,this paper proposes an innovative design scheme for the calibrator.This device demonstrates significant effects in enhancing the accuracy and stability of power system calibration,providing robust technical support for the optimization and upgrade of the power system.This research not only offers a theoretical basis and practical guidance for the design and application of CT secondary cable line calibrators but also contributes new ideas and methods for the precise calibration and efficient management of the power system. 展开更多
关键词 CT secondary cable line CALIBRAtoR Power system DESIGN application
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Influencing Factors of Chinese Proficiency Test Learning Application Under the Framework of Seamless Learning
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作者 Baohua Su Zhixue Yang Huiming Cao 《Journal of Contemporary Educational Research》 2024年第4期276-289,共14页
With the development of modern information technology and network society,the era of digital transformation has arrived,many educational resources have been developed and utilized,and the problem of space-time separat... With the development of modern information technology and network society,the era of digital transformation has arrived,many educational resources have been developed and utilized,and the problem of space-time separation of global Chinese learners is gradually being solved.The use of mobile application learning can achieve convenient and fast learning,reduce learning costs,and flexibly adjust learning progress.After experiencing COVID-19,the demand for human-computer interaction in mobile learning is even more necessary.Therefore,to make applications achieve seamless docking with the needs of learners in the design of learning,the research investigates and analyzes the five dimensions of time,space,mode,subject,and object.The research tests the reliability and validity of the questionnaire,removes the relevant items and conducts non-parametric tests,then puts forward corresponding strategies according to the results of the questionnaire.It aims to enhance the efficiency of Chinese learners in HSK(Hanyu Shuiping Kaoshi,Chinese Proficiency Test)learning and promote Chinese learning and the spread of the Chinese language and culture. 展开更多
关键词 Seamless learning Hanyu Shuiping Kaoshi application Influencing factors
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Clinical Application Study of Super-Mini Percutaneous Nephrolithotomy in the Treatment of Kidney Stones
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作者 Zehong You Wenyong Lian 《Proceedings of Anticancer Research》 2024年第5期141-145,共5页
Objective:To observe the clinical efficacy and complication rates of different stone fragmentation techniques in the treatment of kidney stones.Methods:This study selected 100 patients with urinary stones treated at t... Objective:To observe the clinical efficacy and complication rates of different stone fragmentation techniques in the treatment of kidney stones.Methods:This study selected 100 patients with urinary stones treated at the Third Division General Hospital from 2021 to November 2023 as subjects.The control group(n=50)received conventional percutaneous nephrolithotomy(PCNL)for stone fragmentation,while the research group(n=50)received super-mini percutaneous nephrolithotomy(SMP)treatment.Surgical parameters,stone clearance rates,recurrence rates,and complication rates were compared between the two groups.Results:After treatment,the surgical parameters in the research group were significantly better than those in the control group.The research group had a higher stone clearance rate and lower rates of stone recurrence and complications(P<0.05).Conclusion:Compared with conventional PCNL,SMP shows better clinical outcomes for patients with kidney stones.It improves surgical parameters,increases stone clearance rates,and reduces both stone recurrence and complication rates,making it a valuable technique for clinical reference. 展开更多
关键词 Super-mini percutaneous nephrolithotomy Kidney stones Stone clearance Clinical application
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The evolution of robotics:research and application progress of dental implant robotic systems 被引量:3
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作者 Chen Liu Yuchen Liu +3 位作者 Rui Xie Zhiwen Li Shizhu Bai Yimin Zhao 《International Journal of Oral Science》 SCIE CAS CSCD 2024年第2期173-185,共13页
The use of robots to augment human capabilities and assist in work has long been an aspiration.Robotics has been developing since the 1960s when the first industrial robot was introduced.As technology has advanced,rob... The use of robots to augment human capabilities and assist in work has long been an aspiration.Robotics has been developing since the 1960s when the first industrial robot was introduced.As technology has advanced,robotic-assisted surgery has shown numerous advantages,including more precision,efficiency,minimal invasiveness,and safety than is possible with conventional techniques,which are research hotspots and cutting-edge trends.This article reviewed the history of medical robot development and seminal research papers about current research progress.Taking the autonomous dental implant robotic system as an example,the advantages and prospects of medical robotic systems would be discussed which would provide a reference for future research. 展开更多
关键词 ROBOT ROBOTIC application
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Drilling-based measuring method for the c-φ parameter of rock and its field application 被引量:3
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作者 Bei Jiang Fenglin Ma +5 位作者 Qi Wang Hongke Gao Dahu Zhai Yusong Deng Chuanjie Xu Liangdi Yao 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第1期65-76,共12页
The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(R... The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(RCZ) is built. The formula for an ultimate cutting force is established based on the limit equilibrium principle. The relationship between digital drilling parameters(DDP) and the c-φ parameter(DDP-cφ formula, where c refers to the cohesion and φ refers to the internal friction angle) is derived, and the response of drilling parameters and cutting ratio to the strength parameters is analyzed. The drillingbased measuring method for the c-φ parameter of rock is constructed. The laboratory verification test is then completed, and the difference in results between the drilling test and the compression test is less than 6%. On this basis, in-situ rock drilling tests in a traffic tunnel and a coal mine roadway are carried out, and the strength parameters of the surrounding rock are effectively tested. The average difference ratio of the results is less than 11%, which verifies the effectiveness of the proposed method for obtaining the strength parameters based on digital drilling. This study provides methodological support for field testing of rock strength parameters. 展开更多
关键词 Digital drilling Rock crushing zone c-u parameter Measurement method Field application
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Improving the nutritional values of yellow mealworm Tenebrio molitor(Coleoptera: Tenebrionidae) larvae as an animal feed ingredient: a review 被引量:1
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作者 Linggawastu Syahrulawal Magnhild Oust Torske +2 位作者 Rumakanta Sapkota Geir Næss Prabhat Khanal 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第1期35-52,共18页
Yellow mealworm larvae(YML;Tenebrio molitor) are considered as a valuable insect species for animal feed due to their high nutritional values and ability to grow under different substrates and rearing conditions. Adva... Yellow mealworm larvae(YML;Tenebrio molitor) are considered as a valuable insect species for animal feed due to their high nutritional values and ability to grow under different substrates and rearing conditions. Advances in the understanding of entomophagy and animal nutrition over the past decades have propelled research areas toward testing multiple aspects of YML to exploit them better as animal feed sources. This review aims to summarize various approaches that could be exploited to maximize the nutritional values of YML as an animal feed ingredient. In addition, YML has the potential to be used as an antimicrobial or bioactive agent to improve animal health and immune function in production animals. The dynamics of the nutritional profile of YML can be influenced by multiple factors and should be taken into account when attempting to optimize the nutrient contents of YML as an animal feed ingredient. Specifically, the use of novel land-based and aquatic feeding resources, probiotics, and the exploitation of larval gut microbiomes as novel strategies can assist to maximize the nutritional potential of YML. Selection of relevant feed supplies, optimization of ambient conditions, the introduction of novel genetic selection procedures, and implementation of effective post-harvest processing may be required in the future to commercialize mealworm production. Furthermore, the use of appropriate agricultural practices and technological improvements within the mealworm production sector should be aimed at achieving both economic and environmental sustainability. The issues highlighted in this review could pave the way for future approaches to improve the nutritional value of YML. 展开更多
关键词 Alternative protein source Feed application Nutritional value Yellow mealworm
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The Application of Bilayer Artificial Dermis Combined with VSD Technology in Chronic Wounds 被引量:1
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作者 Xianjin Dong Huasong Luo 《Journal of Biosciences and Medicines》 2024年第3期238-244,共7页
Background: Bilayer artificial dermis promotes wound healing and offers a treatment option for chronic wounds. Aim: Examine the clinical efficacy of bilayer artificial dermis combined with Vacuum Sealing Drainage (VSD... Background: Bilayer artificial dermis promotes wound healing and offers a treatment option for chronic wounds. Aim: Examine the clinical efficacy of bilayer artificial dermis combined with Vacuum Sealing Drainage (VSD) technology in the treatment of chronic wounds. Method: From June 2021 to December 2023, our hospital treated 24 patients with chronic skin tissue wounds on their limbs using a novel tissue engineering product, the bilayer artificial dermis, in combination with VSD technology to repair the wounds. The bilayer artificial dermis protects subcutaneous tissue, blood vessels, nerves, muscles, and tendons, and also promotes the growth of granulation tissue and blood vessels to aid in wound healing when used in conjunction with VSD technology for wound dressing changes in chronic wounds. Results: In this study, 24 cases of chronic wounds with exposed bone or tendon larger than 1.0 cm2 were treated with a bilayer artificial skin combined with VSD dressing after wound debridement. The wounds were not suitable for immediate skin grafting. At 2 - 3 weeks post-treatment, good granulation tissue growth was observed. Subsequent procedures included thick skin grafting or wound dressing changes until complete wound healing. Patients were followed up on average for 3 months (range: 1 - 12 months) post-surgery. Comparative analysis of the appearance, function, skin color, elasticity, and sensation of the healed chronic wounds revealed superior outcomes compared to traditional skin fl repairs, resulting in significantly higher satisfaction levels among patients and their families. Conclusion: The application of bilayer artificial dermis combined with VSD technology for the repair of chronic wounds proves to be a viable method, yielding satisfactory therapeutic effects compared to traditional skin flap procedures. 展开更多
关键词 Bilayer Artificial Dermis Vacuum Sealing Drainage (VSD) Chronic Wounds Wound Healing application
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Heating of nanoparticles and their environment by laser radiation and applications
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作者 Victor K.Pustovalov 《Nanotechnology and Precision Engineering》 EI CAS CSCD 2024年第1期78-115,共38页
This review considers the fundamental dynamic processes involved in the laser heating of metal nanoparticles and their subsequent cooling.Of particular interest are the absorption of laser energy by nanoparticles,the ... This review considers the fundamental dynamic processes involved in the laser heating of metal nanoparticles and their subsequent cooling.Of particular interest are the absorption of laser energy by nanoparticles,the heating of a single nanoparticle or an ensemble thereof,and the dissipation of the energy of nanoparticles due to heat exchange with the environment.The goal is to consider the dependences and values of the temperatures of the nanoparticles and the environment,their time scales,and other parameters that describe these processes.Experimental results and analytical studies on the heating of single metal nanoparticles by laser pulses are discussed,including the laser thresholds for initiating subsequent photothermal processes,how temperature influences the optical properties,and the heating of gold nanoparticles by laser pulses.Experimental studies of the heating of an ensemble of nanoparticles and the results of an analytical study of the heating of an ensemble of nanoparticles and the environment by laser radiation are considered.Nanothermometry methods for nanoparticles under laser heating are considered,including changes in the refractive indices of metals and spectral thermometry of optical scattering of nanoparticles,Raman spectroscopy,the thermal distortion of the refractive index of an environment heated by a nanoparticle,and thermochemical phase transitions in lipid bilayers surrounding a heated nanoparticle.Understanding the sequence of events after radiation absorption and their time scales underlies many applications of nanoparticles.The applicationfields for the laser heating of nanoparticles are reviewed,including thermochemical reactions and selective nanophotothermolysis initiated in the environment by laser-heated nanoparticles,thermal radiation emission by nanoparticles and laser-induced incandescence,electron and ion emission of heated nanoparticles,and optothermal chemical catalysis.Applications of the laser heating of nanoparticles in laser nanomedicine are of particular interest.Significant emphasis is given to the proposed analytical approaches to modeling and calculating the heating processes under the action of a laser pulse on metal nanoparticles,taking into account the temperature dependences of the parameters.The proposed models can be used to estimate the parameters of lasers and nanoparticles in the various applicationfields for the laser heating of nanoparticles. 展开更多
关键词 NANOPARTICLES LASER HEATING MODELING Nanothermometry applications
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Impact of nanoparticles on immune cells and their potential applications in cancer immunotherapy
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作者 JYOTHI B.NAIR ANU MARY JOSEPH +1 位作者 SANOOP P MANU M.JOSEPH 《BIOCELL》 SCIE 2024年第11期1579-1602,共24页
Nanoparticles represent a heterogeneous collection of materials,whether natural or synthetic,with dimensions aligning in the nanoscale.Because of their intense manifestation with the immune system,they can be harveste... Nanoparticles represent a heterogeneous collection of materials,whether natural or synthetic,with dimensions aligning in the nanoscale.Because of their intense manifestation with the immune system,they can be harvested for numerous bio-medical and biotechnological advancements mainly in cancer treatment.This review article aims to scrutinize various types of nanoparticles that interact differently with immune cells like macrophages,dendritic cells,T lymphocytes,and natural killer(NK)cells.It also underscores the importance of knowing how nanoparticles influence immune cell functions,such as the production of cytokines and the presentation of antigens which are crucial for effective cancer immunotherapy.Hence overviews of bio-molecular mechanisms are provided.Nanoparticles can improve antigen presentation,boost T-cell responses,and overcome the immunosuppressive tumor environment.The regulatory mechanisms,signaling pathways,and nanoparticle characteristics are also presented for a comprehensive understanding.We review the nanotechnology platform options and challenges in nanoparticlesbased immunotherapy,from an immunotherapy perspective including precise targeting,immune modulation,and potential toxicity,as well as personalized approaches based on individual patient and tumor characteristics.The development of emerging multifunctional nanoparticles and theranostic nanoparticles will provide new solutions for the precision and efficiency of cancer therapies in next-generation practice. 展开更多
关键词 NANOTECHNOLOGY MACROPHAGES Dendritic cells Antigen presentation T lymphocytes
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Study on the Application of Refined Nursing Care in The Care for Elderly Patients with Reflux Esophagitis 被引量:1
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作者 Zhe Chen Rui Cao 《Journal of Clinical and Nursing Research》 2024年第4期69-72,共4页
Objective: To investigate the application effect of refined nursing care in the care for elderly patients with reflux esophagitis. Methods: Following the difference in nursing style, 84 cases of elderly patients with ... Objective: To investigate the application effect of refined nursing care in the care for elderly patients with reflux esophagitis. Methods: Following the difference in nursing style, 84 cases of elderly patients with reflux esophagitis admitted to our hospital from May 2022 to May 2023 were randomly grouped into a control group and a research group, with 42 cases each. The control group was given conventional nursing care and the research group was given refined nursing care. The psychological state and treatment adherence of the two groups of patients after the nursing intervention were compared. Results: After the nursing intervention, the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores of the research group were lower than those of the control group (P < 0.05). The treatment compliance of the research group was better than the control group (P < 0.05). Conclusion: The implementation of refined nursing care for elderly patients with reflux esophagitis exhibited a significant effect on improving the patient’s psychological state, treatment compliance, and rehabilitation. 展开更多
关键词 Geriatric reflux esophagitis Refined nursing care application research
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Renewable Polymers in Biomedical Applications:From the Bench to the Market
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作者 Rauany Cristina Lopes Tamires Nossa +3 位作者 Wilton Rogério Lustri Gabriel Lombardo Maria Inés Errea Eliane Trovatti 《Journal of Renewable Materials》 EI CAS 2024年第4期643-666,共24页
Polymers from renewable resources have been used for a long time in biomedical applications and found an irreplaceable role in some of them.Their uses have been increasing because of their attractive properties,contri... Polymers from renewable resources have been used for a long time in biomedical applications and found an irreplaceable role in some of them.Their uses have been increasing because of their attractive properties,contributing to the improvement of life quality,mainly in drug release systems and in regenerative medicine.Formulations using natural polymer,nano and microscale particles preparation,composites,blends and chemical modification strategies have been used to improve their properties for clinical application.Although many studies have been carried out with these natural polymers,the way to reach the market is long and only very few of them become commercially available.Vegetable cellulose,bacterial cellulose,chitosan,poly(lactic acid)and starch can be found among the most studied polymers for biological applications,some with several derivatives already established in the market,and others with potential for such.In this scenario this work aims to describe the properties and potential of these renewable polymers for biomedical applications,the routes from the bench to the market,and the perspectives for future developments. 展开更多
关键词 POLYMERS RENEWABLE biomedical applications MARKET
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The immunomodulatory effects and mechanisms of magnesium-containing implants in bone regeneration:A review
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作者 Qiang Sun You Zhou +3 位作者 Aixue Zhang Jibin Wu Lili Tan Shu Guo 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第7期2695-2710,共16页
Traditional designs and developments of bone biomaterials mostly concentrate on the positive regulation of osteoblast lineage cells,but often ignore the importance of immune responses and the equilibrium between bone ... Traditional designs and developments of bone biomaterials mostly concentrate on the positive regulation of osteoblast lineage cells,but often ignore the importance of immune responses and the equilibrium between bone resorption mediated by osteoclasts and bone formation mediated by osteoblasts.Immune dysregulation is associated with an imbalance between pro-inflammatory and anti-inflammatory processes,which may influence the efficacy of bone therapy.Therefore,implanted biomaterials should appropriately and precisely modulate subsequent immune responses.Magnesium(Mg)has been used to fabricate various Mg alloys for bone repair because of its favorable attributes such as osteogenic potential,immune regulation characteristics,biodegradability,and biocompatibility.Various basic research and clinical trials have been already conducted in many countries to explore the physical properties of Mg-containing implants and their clinical outcomes in bone fracture and defect repair.Therefore,this review summarizes the immune response to Mg-containing implants,and further organizes the current research and development progress of Mg-containing implants.The review aims to offer an overview of the current knowledge on immunomodulation of Mg-containing implants and future challenges in their clinical application,which could provide further insight in the development of better strategies for the treatment of bone defect and fracture. 展开更多
关键词 MAGNESIUM Bone regeneration Immune response BIOMATERIALS Clinical application
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Clinical Presentation and Treatment Outcomes of Pregnancy-Related Acute Kidney Injury among Pregnant Women Admitted at the Benjamin Mkapa Hospital in Tanzania
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作者 Kessy Shija Hindu Ibrahim +3 位作者 Sylvia Jumbe Bushi Lugoba Stephen Mathew Kibusi Alphonce Chandika 《Open Journal of Nephrology》 2024年第2期157-175,共19页
Background: Globally, PRAKI is among the leading causes of death in pregnant women. The prevalence, causes and outcome of this condition vary among countries due to differences in environmental, socioeconomic, and hea... Background: Globally, PRAKI is among the leading causes of death in pregnant women. The prevalence, causes and outcome of this condition vary among countries due to differences in environmental, socioeconomic, and health delivery systems. The common causes that have been reported in several studies are PIH, Haemorrhages and Sepsis while the outcomes may be either complete renal recovery, progression to CKD and hence dialysis dependency or death. This study aimed at determining clinical presentation and treatment outcomes of Pregnancy-Related Acute Kidney Injury in Pregnant women admitted at the Benjamin Mkapa Hospital, Dodoma, Tanzania. Results: Out of 4007 pregnant women who were admitted to the maternity ward 51 pregnant women were found to have PRAKI. Of those with PRAKI, 74.5% were between 21 to 25 years. The leading causes of PRAKI were PPH 12 (23.53%), Eclampsia 12 (23.53%), and pre-eclampsia 12 (23.5%). Hemodialysis therapy was provided to 22 (43.1%) patients, 15 (29.4%) individuals recovered spontaneously with medical management and 14 (27.5%) missed haemodialysis therapy due to various reasons. The mortality due to PRAKI was 17 (33.3%). Conclusion and Recommendation: Pre-eclampsia/eclampsia and post-partum haemorrhage were found to be the main causes of PRAKI. The mortality related to PRAKI is high and Hemodialysis therapy is vital help to prevent deaths for pregnant women with PRAKI. Pregnant women who develop acute kidney injury should be followed closely and a nephrologist should be consulted early. Early referral should be done by the lower level facilities for all at-risk pregnant women to a specialized multidisciplinary health facility. 展开更多
关键词 Clinical presentation Treatment Outcomes Pregnancy-Related Acute Kidney Injury
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Platelet-derived microparticles and their cargos: The past, present and future
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作者 Jingwen Guo Bufeng Cui +5 位作者 Jie Zheng Chang Yu Xuran Zheng Lixin Yi Simeng Zhang Keke Wang 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2024年第2期72-88,共17页
All eukaryotic cells can secrete extracellular vesicles, which have a double-membrane structure and are important players in the intercellular communication involved in a variety of important biological processes. Pla... All eukaryotic cells can secrete extracellular vesicles, which have a double-membrane structure and are important players in the intercellular communication involved in a variety of important biological processes. Platelets form platelet-derived microparticles (PMPs) in response to activation, injury, or apoptosis. This review introduces the origin, pathway, and biological functions of PMPs and their importance in physiological and pathological processes. In addition, we review the potential applications of PMPs in cancer, vascular homeostasis, thrombosis, inflammation, neural regeneration, biomarkers, and drug carriers to achieve targeted drug delivery. In addition, we comprehensively report on the origin, biological functions, and applications of PMPs. The clinical transformation, high heterogeneity, future development direction, and limitations of the current research on PMPs are also discussed in depth. Evidence has revealed that PMPs play an important role in cell-cell communication, providing clues for the development of PMPs as carriers for relevant cell-targeted drugs. The development history and prospects of PMPs and their cargos are explored in this guidebook. 展开更多
关键词 Platelet-derived particles application Heter ogeneity Potential and limitations
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The Contribution of AI-Powered Mobile Apps to Smart City Ecosystems
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作者 Zaki Ali Bayashot 《Journal of Software Engineering and Applications》 2024年第3期143-154,共12页
In the groundbreaking study “The Contribution of AI-powered Mobile Apps to Smart City Ecosystems,” authored by Zaki Ali Bayashot, the transformative role of artificial intelligence (AI) in urban development is metic... In the groundbreaking study “The Contribution of AI-powered Mobile Apps to Smart City Ecosystems,” authored by Zaki Ali Bayashot, the transformative role of artificial intelligence (AI) in urban development is meticulously examined. This comprehensive research delineates the multifaceted ways in which AI-powered mobile applications can significantly enhance the efficiency, sustainability, and livability of urban environments, marking a pivotal step towards the realization of smart cities globally. Bayashot meticulously outlines the critical areas where AI-powered apps offer unprecedented advantages, including urban mobility, public safety, energy management, and environmental monitoring. By leveraging AI’s capabilities, these applications not only streamline city operations but also foster a more sustainable interaction between city dwellers and their environment. The paper emphasizes the importance of data-driven decision-making in urban planning, showcasing how AI analytics can predict and mitigate traffic congestion, optimize energy consumption, and enhance emergency response strategies. The author also explores the social implications of AI in urban settings, highlighting the potential for these technologies to bridge the gap between government entities and citizens. Through engaging case studies, Bayashot demonstrates how participatory governance models, enabled by AI apps, can promote transparency, accountability, and citizen engagement in urban management. A significant contribution of this research is its focus on the challenges and opportunities presented by the integration of AI into smart city ecosystems. Bayashot discusses the technical, ethical, and privacy concerns associated with AI applications, advocating for a balanced approach that ensures technological advancements do not come at the expense of civil liberties. The study calls for robust regulatory frameworks to govern the use of AI in public spaces, emphasizing the need for ethical AI practices that respect privacy and promote inclusivity. Furthermore, Bayashot’s research underscores the necessity of cross-disciplinary collaboration in the development and implementation of AI technologies in urban contexts. By bringing together experts from information technology, urban planning, environmental science, and social sciences, the author argues for a holistic approach to smart city development. This interdisciplinary strategy ensures that AI applications are not only technologically sound but also socially and environmentally responsible. The paper concludes with a visionary outlook on the future of smart cities, posited on the seamless integration of AI technologies. Bayashot envisions a world where AI-powered mobile apps not only facilitate smoother urban operations but also empower citizens to actively participate in the shaping of their urban environments. This research serves as a critical call to action for policymakers, technologists, and urban planners to embrace AI as a tool for creating more sustainable, efficient, and inclusive cities. By presenting a detailed analysis of the current state of AI in urban development, coupled with practical insights and forward-looking recommendations, “The Contribution of AI-powered Mobile Apps to Smart City Ecosystems” stands as a seminal work that is poised to inspire and guide the evolution of urban landscapes worldwide. Its comprehensive exploration of the subject matter, combined with its impactful conclusions, make it a must-read for anyone involved in the field of smart city development, AI technology, or urban policy-making. 展开更多
关键词 Mobile applications Smart Cities Artificial Intelligence IOT
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Advances in clinical applications of bioceramics in the new regenerative medicine era
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作者 Noha Elshazly Fayza Eid Nasr +2 位作者 Ayat Hamdy Safa Saied Mohamed Elshazly 《World Journal of Clinical Cases》 SCIE 2024年第11期1863-1869,共7页
In this editorial,we comment on the hard and soft tissue applications of different ceramic-based scaffolds prepared by different mechanisms such as 3D printing,sol-gel,and electrospinning.The new concept of regenerati... In this editorial,we comment on the hard and soft tissue applications of different ceramic-based scaffolds prepared by different mechanisms such as 3D printing,sol-gel,and electrospinning.The new concept of regenerative medicine relies on biomaterials that can trigger in situ tissue regeneration and stem cell recruitment at the defect site.A large percentage of these biomaterials is ceramic-based as they provide the essential requirements of biomaterial principles such as tailored multisize porosity,antibacterial properties,and angiogenic properties.All these previously mentioned properties put bioceramics on top of the hierarchy of biomaterials utilized to stimulate tissue regeneration in soft and hard tissue wounds.Multiple clinical applications registered the use of these materials in triggering soft tissue regeneration in healthy and diabetic patients such as bioactive glass nanofibers.The results were promising and opened new frontiers for utilizing these materials on a larger scale.The same results were mentioned when using different forms and formulas of bioceramics in hard defect regeneration.Some bioceramics were used in combination with other polymers and biological scaffolds to improve their regenerative and mechanical properties.All this progress will enable a larger scale of patients to receive such services with ease and decrease the financial burden on the government. 展开更多
关键词 Regenerative medicine BIOCERAMICS Chronic wounds Bone defects Clinical applications
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