Housing Typologies and Appropriation of the Urban Form in Alvalade＇s Neighborhood, Lisbon

The Alvalade＇s neighborhood （Lisbon, Portugal）, 1945, as a paradigm of Portuguese urbanism, can be distinguished by different housing cells that define it, as well as the different urban models, which relied on. It is possible to identify distinct occupational stains within the neighborhood, specifically in the cell one in this article, as a pioneer construction, due to housing dimension that corresponds to different housing typologies, residents and daily use areas, equipment. The objective is therefore, to understand how these three factors are reflected inside the cell, managing occupational stains which differ in space appropriation. How those different occupational stains that derive from the housing and urban morphology, may result in the occupation and experience of its inhabitants, not invalidating a cohesive structure of the neighborhood？

The place of the Great Mosque of Tlemcen:the paradox between patrimonialisation and appropriation

The Great Mosque of Tlemcen is a unique case,as it is one of the few mosques dating back to the Almoravid period that is almost intact.It has evolved in a constantly changing space and now has a conjoined public square,following an occidental configuration,which is quite rare.The size of this square suggests that it could be put to use as an additional vector for the valorisation of the mosque,but the current situation is different.This added space,introduced by occidental culture,creates a dual architectural language with several other buildings that mark all the layers of evolution in the urban fabric.Apart from its religious function,this mosque used to play the role of a covered public square,a role that has eroded over time.The aim of this research is to analyse the relationship between the building and its surroundings,as well as the population’s perception of this relationship.Additionally,the research is intended to highlight changes in the perception of the Great Mosque of Tlemcen’s public square over time,depending on historical,political,and social contexts.This research relies on an approach that combines different methods,including a thorough analysis of historical,cartographic,and legislative documents.Through this approach,we were able to conduct a comparative analysis with other similar cases.Finally,field research allowed us to understand the relationship between space and society.Despite the legal recognition of the surroundings as a historical monument,this status is not widely perceived and integrated into the population’s sense of heritage space.This is reflected in private and even public actions,despite the instrumentalisation of this heritage status,with appropriations of protected space that occur outside of regulations and become part of the landscape expression of the building in its environment.

From appropriation to formal intervention:An analytical framework for understanding the appropriation process in residual spaces of Cairo

The paper addresses the issue of how residual spaces are intervened upon through formal and informal processes.It argues that a profound understanding for the dynamics of informal interventions,denoted by appropriation,could enhance the performance of their formal peers.Adopting a qualitative approach,the paper departs from Lefebvre's unitary theory of space and arrives at an analytical framework that helps to understand the appropriation processes in residual spaces.It,then,attempts to empirically challenge the applicability of this framework through analyzing a Cairene residual space that has undergone two cycles of intervention:a formal and informal one.

Optimizing polypharmacy interventions and evaluating their impact on elderly inpatients using dual criteria and medication appropriateness index

With the acceleration of society’s aging process,the widespread phenomenon of polypharmacy among the elderly has become a significant concern.This research aimed to analyze potential inappropriate medication among 178 inpatients in the geriatric general department of our hospital from January 2022 to September 2022.The participants were randomly assigned to an observation group and a control group.The observation group received pharmaceutical intervention,whereas the control group did not.The objective was to explore the impact of pharmaceutical intervention on polypharmacy in this population.The results revealed that after pharmaceutical intervention,there were no significant differences in medication adherence,medication appropriateness index(MAI),quantity of medicine,and potentially inappropriate medication(PIM)in the control group compared to before the intervention(P>0.05).However,the observation group showed significant improvement(P<0.05).The proportion of patients with good adherence increased from 57%to 78%,and the percentage of patients with MAI scores over 10 decreased from 60%to 40%.Moreover,there was a reduction in the number of medications prescribed,with only 47%of patients receiving more than five different types compared to the initial rate of 64%.Additionally,the occurrence of PIM declined from an initial rate of 64%to just 44%,surpassing that observed in the control group.Therefore,the implementation of pharmaceutical intervention can effectively enhance medication adherence and appropriateness among elderly patients,mitigate the risk of PIM,and promote rational medicine utilization.

Spousal Involvement in the Workplace of Doctors: What Is Defined as Appropriate or Inappropriate

Background: Workers spend a significant amount of time in the workspace. Involvement of a spouse in a doctor’s workplace can take different forms and come with different intentions. Objectives: The survey aimed to determine the prevalence and extent of spousal involvement in physicians’ workplaces as well as the outcome of such involvement on doctor’ swell-being, productivity, and relationship with colleagues. Methods: This cross-sectional online survey on spousal involvement in the workplace of doctors was conducted among 83 responding doctors from July to August 2023. Results: Among the respondents, 60 (72.3%) had witnessed a doctor’s spouse being involved in the workplace. The most common reason for spousal involvement in the workplace was to protect the spouse from what they perceived as a threat 34 (54.0%). Spouse’s ignorance of boundaries in the workplace (OR: 6.09 (95% CI: 1.70, 21.79) P: 0.003) and exertion of control by the spouse (OR: 11.2 (95% CI: 2.26, 56.41) P: 0.002) were significantly associated with higher odds of inappropriate spousal involvement in the workplace, while expression of love for spouse with acts of kindness was significantly associated with a lowered odd of inappropriate spousal involvement (OR: 0.11 (95% CI: 0.03, 0.36) P: 0.0001). Conclusion: Spousal involvement in the workplace is relatively common. Ignorance of the boundaries of the workplace and exertion of control by the spouse were significant enablers of inappropriate spousal involvement in the workplace of doctors. The establishment of workplace policies that define the limits of spousal involvement in the doctor’s workplace can foster a healthy workspace environment, enhance doctors’ well-being, and improve patient care.

农机社会化服务对小农生计的影响——基于“占取主义”理论视角的分析

如何在农业资本化的背景下保护小农的利益是中国农业现代化要解决的重要问题,可运用“占取主义”理论考察农机社会化服务对小农生计的影响。研究发现,随着农机社会化服务产业的不断发展壮大,农机服务提供者通过取代家庭劳动力投入,实现了对农业剩余的部分占取。研究认为,农机社会化服务是农业资本化的重要组成部分,本质是农业生产资料的日益商品化。农机社会化服务在将小农从农业中解放出来的同时,也带来一些问题。小农的农业收益越来越低,对资本的依赖和从属程度不断加深,存在被边缘化的窘境。鉴于此,建议通过加快健全种粮农民收益保障机制、不断完善农业社会化服务体系、创新提高农户组织化程度的方式方法等,遏制资本对农业剩余的过度切割,探索出一条超越资本化、具有中国特色的农业现代化路径,保护好小农的利益。

Appropriateness of Amikacin Dose Prescription, Monitoring and Safety during Hospitalization as an Impact of Clinical Pharmacologist Intervention, in the Israeli Regional Hospital

Background: Use of inappropriate amikacin dose is one of the most important factors in inducing toxicity, prolonged hospitalization as well as in increasing patient’s mortality. Objective: The aims of this study are the analysis of amikacin dose, serum level and the examination of the effectiveness of the clinical pharmacologist (CP) therapeutic drug monitoring (TDM) intervention to guarantee the safety of amikacin use. Methods: This is a one-year retrospective observational chart review study, which evaluates amikacin dose, serum drug level, development of adverse effects in patients on amikacin with or without CP TDM consultation. Results: Amikacin was prescribed for 393 complex patients, with median age 83. Amikacin group (AG) included 140 (32%) courses with CP consultation (AG1) and 292 (68%) courses without CP consultation (AG2). The distribution of most study characteristics in both groups was similar including amikacin dose (9-10 mg/kg/day), renal failure (14%) and mortality (12%). Acceptance for CP consultation was in 46% of amikacin courses and dose changes were done in 63% after CP intervention. Prolonged antibiotic course (4.6 ± 1.5 vs 3.8 ± 1.6 days, p < 0.0001) and the patient’s hemodynamic instability (15% vs 7%, p = 0.01) were more frequent in the AG1 compared to the AG2. There was a strong association between CP consultation and prolonged hospitalization (p = 0.005), while no association between it and amikacin adverse effects, renal failure or mortality. Conclusions: There was no trend to reducing amikacin toxicity, days of hospitaliza tion or mortality in patients with CP consultation. CP TDM intervention was more in the management of complicated clinical situations. However, it is necessary to optimize it.

Appropriation of Innovation and Patent Behaviors of Technological Firms in the Yangtze Delta Area

In the transition from ＂made in China＂ to ＂invented in China,＂ what is the motivation of Chinese firms in applying for patents？ Why do some firms bypass patents？ How is patenting developing within Chinese firms？ This paper attempts to answer these questions using data of Chinese firms in the Yangtze River Delta region. Results indicate that, for product innovation, obtaining the lead time for market entry is of top priority in innovation protection, followed by confidentiality and patent protection. As for process innovation, confidentiality ranks first, followed by patent protection and obtaining the lead time. There is a significant and positive relationship between prior experience of patent licensing and possibility of future patent licensing. Firms with painful patent litigation experience tend to avoid it in the future. It is also found that there are great differences in patent behaviors between Chinese enterprises and their foreign counterparts.

我国公立医院财政拨款收入的结构变动特征分析

目的 分析公立医院财政拨款收入的结构变动特征。方法 基于2011—2020年将考察时间段调整为2010—2019年《中国卫生健康统计年鉴》的数据,应用结构变动度分析方法。结果 2010—2019年,全国公立医院的财政拨款收入规模呈现逐年上升的趋势。我国不同级别公立医院的财政拨款结构变动贡献率从大到小依次为三级医院(58.43%)、二级医院(39.26%)、基层医疗卫生机构(2.31%)。各类公立医院的贡献率从大到小依次为精神病医院(40.25%)、综合医院(17.13%)、传染病医院(14.64%)、中医(民族)医院(7.85%)、儿童医院(6.00%)、妇产医院/妇幼保健院(5.35%)、其他专科医院(4.90%)、职业病防治院(3.88%)。结论 需要政府落实职责,在财政拨款安排中重视各类型、各级别公立医院的合理平衡,科学规划财政投入标准及支持力度,进一步推动分级诊疗制度,保证不同类型、级别医院的平稳运行。

中医药适宜技术推广协同治理机制构建研究

目的通过构建中医药适宜技术推广协同治理机制,增强群众对中医药适宜技术的接受度,为进一步提升中医药适宜技术推广应用的力度与深度提供参考。方法梳理中医药适宜技术相关政策,运用协同治理理论,从协同驱动主体、制度保障、服务资源3个维度思考中医药适宜技术推广协同运转机制。结果结合协同驱动主体、制度保障、服务资源3个维度的要素,构建横向联动、纵向同质化执行的中医药适宜技术推广协同治理机制。结论基于协同驱动主体、制度保障、服务资源3个维度构建的中医药适宜技术推广协同治理机制,对于提高中医药适宜技术的普及性、满足基层群众多元化多层次健康需求具有现实意义。

Examination of the Appropriateness of Teaching Materials for Preventing Dangers during Ablution and Bathing of Infants by Mothers and Family Members

Purpose: This study aimed to develop teaching materials to prevent the dangers of ablution and bathing infants, based on the dangerous experiences of mothers and family members, and examine their appropriateness. Methods: A total of 20 midwives and public health nurses were selected as participants. Teaching materials and anonymous self-administered questionnaires were distributed, and the participants were asked to view the teaching materials and fill in the questionnaires. Retrieval was done by mail. The teaching materials included digital content, such as videos, sounds, and characters, which incorporated dangerous situations, preventions, and innovations in ablution and bathing procedures. The analysis was conducted by simple tabulation for each survey item. The free description was coded to preserve anonymity. This study was conducted with the approval of the Research Ethics Review Board of the authors’ affiliated university. Results: The teaching materials were found to be appropriate in terms of suitability to purpose, degree of difficulty of content, ease of viewing the videos, validity of time, appropriateness of expression, and usability. Conclusions: Ablution teaching materials that are used at the present time do not focus on dangers, and to date, no resources on bathing have been used as teaching materials. The created teaching materials in this study can be viewed multiple times, and mothers and family members who are unfamiliar with ablution and bathing can acquire knowledge regarding dangers and danger prevention. The addition of specific preventive measures and countermeasures for the occurrence of danger, along with practice, would result in the development of further appropriate teaching materials to reduce danger and alleviate anxiety.

Transforming Molecules into Medicines: Role of CDMOS in Phase-Appropriate Technology Transfers in Advancing Pharmaceutical Innovation

CDMOs are emerging as critical drivers of innovation within the pharmaceutical and biotech industries. As the pharmaceutical industry continues to evolve, we can expect to see CDMOs play an increasingly important role in drug development and manufacturing. Many companies within these sectors are now leveraging the expertise of CDMOs through technology transfers to foster innovation and enhance the development of new drug products. In the extensive field of drug development, technology transfer plays a crucial role at multiple stages, ranging from preclinical phases to commercialization. By working closely with drug developers, CDMOs can ensure that technologies are transferred seamlessly between phases of drug development, allowing for a more efficient and cost-effective development process. CDMOs also bring a wealth of experience in various areas of drug development, including process development, analytical testing, quality control, and manufacturing. This expertise, combined with a focus on innovation, can help drug developers to overcome technical challenges and optimize their drug development programs. CDMOs can provide drug developers with various manufacturing capabilities, from small-scale clinical trials to large-scale commercial production. This flexibility allows drug developers to focus on their core competencies while relying on CDMOs to provide the necessary infrastructure and support for drug manufacturing. The critical role of CDMOs in advancing pharmaceutical innovation in phase-appropriate technology transfer where there will be a lot of effort and patience with strong technical expertise is required. This article explores the various types of Technology transfer from preclinical to commercial stages and successful strategies to foster innovation.

农业技术变迁与农业转型:占取主义/替代主义理论述评

《从农耕到生物技术:关于农业产业化的发展理论》一书从政治经济学角度讨论了技术变迁与农业资本化的关系,提出了占取主义/替代主义的理论框架,强调了由于自然条件的限制,资本无法在农业中建立一个超越家庭之外的更优生产模式,小规模家庭农业因此得以继续存在,但技术的进步,使工业资本可以不断加强对农业领域的渗透和控制。该理论对于理解中国农业转型具有启发意义,农业的资本化并不一定伴随着土地流转和规模化,资本可以通过对农业不同环节的改造、重组,从农业中占取剩余,形成资本积累。此外,国内农业社会学领域的研究发现,家庭农业的存续得益于"家庭"这一生产组织的独特优势,即家庭的村庄社会基础,这也构成对该书的重要拓展。

Appropriate Garden Design of Primitive Ecology Based on the Indigenization of Environmental Ethics

The accelerating urbanization process leads to aggravated environmental problems, thus garden design which is a creative activity connecting human and nature has attracted much attention, and also garden designers have had to rethink about environmental ethics and morals. This study, from the perspective of environmental ethics, duly proposed the brand-new concept of 'appropriate garden of primitive ecology', proceeded from the orientation, form, value, theoretical basis, realistic significance, culture and consumption psychology of 'garden of primitive ecology', fully developed outstanding ecological wisdoms and morals in traditional Chinese garden culture, boosted garden designs to the environmental ethics level of eco-justice, to seek for the approach to 'garden of primitive ecology' with indigenous Chinese environmental ethic characteristics.

Experimental and Numerical Study of Structural Identification Using Non-Linear Resonant Decay Method

One of the practical approaches in identifying structures is the non-linear resonant decay method which identifies a non-linear dynamic system utilizing a model based on linear modal space containing the underlying linear system and a small number of extra terms that exhibit the non-linear effects.In this paper,the method is illustrated in a simulated system and an experimental structure.The main objective of the non-linear resonant decay method is to identify the non-linear dynamic systems based on the use of a multi-shaker excitation using appropriated excitation which is obtained from the force appropriation approach.The experimental application of the method is indicated to provide suitable estimates of modal parameters for the identification of non-linear models of structures.

Expression of Humanity in Highway Landscape Design

Creation of human landscape is the important component of highway landscape design,which has incomparable advantage in the aspects of transmitting cultural atmosphere and expressing regional features.It can not only beautify highway environment,but also serve for traffic function.It is another effective approach to ensure traffic safety.The paper has analyzed existing problems and insufficiencies of modern highway human construction,and discussed the means and methods of expression of historical humanized landscape in highway landscape design.The paper has considered that during design of highway human landscape,it should fully explore historical and humanized background along the highway,extract cultural spirit,enrich cultural connotation,and oppose coarse and fictitious design on the basis of respecting culture and history.

Ecological footprint of food consumption in China:1982-2004

This paper calculates the land (including water area) requirement for food consumption in both balanced andactual diet in China by ecological footprint analysis. To determine whether logical and actual food demands are withinnatural regenerative ability, carrying capacity (excluding forestry production) is also calculated. Results show that actualdiet patterns were ecologically friendly in the period of 1982-2004 in China, mainly because of the rural moderate dietpatterns. But actual per capita footprint already overran its corresponding logic value of 0.976ha in urban areas in 2002.Productive areas for food production can satisfy the land requirement for actual diet patterns during the researchingperiod in China, nevertheless cannot satisfy that for balanced diet pattern or solve the problem of unbalanced ecologicalfootprint. The continual rising ecological footprint of food consumption in both rural and urban areas indicates that percapita footprint will keep on increasing in China and even may be more than the suggested logic value if no relevantcountermeasures are made to regulate diet patterns. Strictly speaking, China is facing food shortage, both in quality andin quantity.

鲁迅信仰符码的当代解译——关于公共话语场域中三个鲁迅问题的论战

鲁迅自身信仰有一个既相互关联又彼此相异的内部逻辑,这一逻辑所演绎出来的信仰形态在历史继承中逐渐成为含义丰富的符码。新时期以来针对深化改革的诸多问题,以鲁迅为核心产生了多次论辩。解译鲁迅信仰符码的立场和态度,从本质上看就是各个阵营或阶层对社会发展方向的把握和意图。对相关解译的回顾和整理,有助于认清鲁迅内在的复杂性和外在的指向性,同时也能为若干现实问题的解决提供参照。

Effect of conceptual fluency on English oral communication

Recent research has found that L2 learners of high grammatical proficiency will not necessarily show concomitant pragmatic skills. On the basis of Danesi＇s Conceptual Fluency theory and actual learners＇ oral abilities, this research conducted two types of tests： a discourse-completion test and a dialogue-interpretation test. The research has found that L2 learners are often influenced by L1 conceptual system, and speeches are not necessarily appropriate and native-like.