In this study,the effects of geometrical and physical factors on light particles dispersion in stirred tank were investigated by agitation characteristic curve.The experiments and CFD simulations with discrete phase m...In this study,the effects of geometrical and physical factors on light particles dispersion in stirred tank were investigated by agitation characteristic curve.The experiments and CFD simulations with discrete phase model(DPM)and volume of fluid model(VOF)were conducted in this paper.Five factors,which include four geometrical factors(submergence,impeller-to-tank ratio,number of impeller blades and baffling mode)and a physical factor(liquid viscosity)were considered.For each factor,the power consumption curve and agitation characteristic curve were drawn to compare the power consumption and mixing results in the stirred tank.Characteristics of the agitation characteristic curves were compared with the previous published literatures and theories.It is found that the agitation characteristic curves reflect the tendency of power consumption and particles distribution well in stirred tank.The good agreement indicates the applicability of the agitation characteristic curves for the study of light particles distribution in stirred tank.展开更多
A novel type curve is presented for oil recovery factor prediction suitable for gas flooding by innovatively introducing the equivalent water-gas cut to replace the water cut,comprehensively considering the impact of ...A novel type curve is presented for oil recovery factor prediction suitable for gas flooding by innovatively introducing the equivalent water-gas cut to replace the water cut,comprehensively considering the impact of three-phase flow(oil,gas,water),and deriving the theoretical equations of gas flooding type curve based on Tong’s type curve.The equivalent water-gas cut is the ratio of the cumulative underground volume of gas and water production to the total underground volume of produced fluids.Field production data and the numerical simulation results are used to demonstrate the feasibility of the new type curve and verify the accuracy of the prediction results with field cases.The new type curve is suitable for oil recovery factor prediction of both water flooding and gas flooding.When a reservoir has no gas injected or produced,the gas phase can be ignored and only the oil and water phases need to be considered,in this case,this gas flooding type curve returns to the Tong’s type curve,which can evaluate the oil recovery factor of water flooding.For reservoirs with equivalent water-gas cuts of 60%-80%,the regression method of the new type curve works well in predicting the oil recovery factor.For reservoirs with equivalent water-gas cuts higher than 80%,both the regression and assignment methods of the new type curve can accurately predict the oil recovery factor of gas flooding.展开更多
Although high-dose methotrexate(HD-MTX)is the most effective drug against primary CNS lymphomas(PCNSL),outcome-de-termining variables related to its administration schedule have not been defined.The impact on toxicity...Although high-dose methotrexate(HD-MTX)is the most effective drug against primary CNS lymphomas(PCNSL),outcome-de-termining variables related to its administration schedule have not been defined.The impact on toxicity and outcome of the area under thecurve(AUC(MTX)),dose intensity(DI(MTX))and infusion rate(IR(MTX))of MTX and plsamatic creatinine clearance(CL(crea))was investigated in a retrospective series of 45 PCNSL patients treated with three different HD-MTX-basedcombinations.Anticon-vulsants were administered in 31 pts(69%).Age>60 years,anticonvulsant therapy,slow IR(MTX)(</=800 mgm(-2)h(-1)),and reduced DI(MTX)(</=1000 mgm(-2)wk(-1))were significantly correlated with low AUC(MTX)values.Seven pa-展开更多
By adopting the method of controlling parameters this paper describes the construction of various kinds of cubic curve segment and curved surface fragment with rational and non rational parameters, and discusses the ...By adopting the method of controlling parameters this paper describes the construction of various kinds of cubic curve segment and curved surface fragment with rational and non rational parameters, and discusses the relationship between controlling parameters, weighted factors and types, kinds and characteristics of curve segments and curved surface fragments. A mathematical method is provided for CAGD with abundant connotations, broad covering region, convenience, flexibility and direct simplicity.展开更多
Horizontal alignment greatly affects the speedof vehicles at rural roads. Therefore, it is necessary toanalyze and predict vehicles speed on curve sections.Numerous studies took rural two-lane as research subjectsand ...Horizontal alignment greatly affects the speedof vehicles at rural roads. Therefore, it is necessary toanalyze and predict vehicles speed on curve sections.Numerous studies took rural two-lane as research subjectsand provided models for predicting operating speeds.However, less attention has been paid to multi-lane highwaysespecially in Egypt. In this research, field operatingspeed data of both cars and trucks on 78 curve sections offour multi-lane highways is collected. With the data, correlationbetween operating speed (V85) and alignment isanalyzed. The paper includes two separate relevant analyses.The first analysis uses the regression models toinvestigate the relationships between V85 as dependentvariable, and horizontal alignment and roadway factors asindependent variables. This analysis proposes two predictingmodels for cars and trucks. The second analysisuses the artificial neural networks (ANNs) to explore theprevious relationships. It is found that the ANN modelinggives the best prediction model. The most influential variableon V85 for cars is the radius of curve. Also, for V85 fortrucks, the most influential variable is the median width.Finally, the derived models have statistics within theacceptable regions and they are conceptually reasonable.展开更多
We prove all integral points of the elliptic curve y^2=x^2-30x+133 are (x,y) = (-7,0),(-3,±14),(2, ±9),(6,±13), (5143326,±11664498677), by using the method of algebraic number theory a...We prove all integral points of the elliptic curve y^2=x^2-30x+133 are (x,y) = (-7,0),(-3,±14),(2, ±9),(6,±13), (5143326,±11664498677), by using the method of algebraic number theory and p-adic analysis. Furthermore, we develop a computation method to find all integral points on a class of elliptic curve y^2= (x+α)(x^2-α)(x^2-αx+b) ,α ,b∈Z,α^2〈4b and find all integer solutions of hyperelliptic Diophantine equation Dy^2=Ax^4 + Bx^2 +C,B^2〈4AC.展开更多
Scattering of SH wave from an interface cylindrical elastic inclusion with a semicircular disconnected curve is investigated. The solution of dynamic stress concentration factor is given using the Green's function an...Scattering of SH wave from an interface cylindrical elastic inclusion with a semicircular disconnected curve is investigated. The solution of dynamic stress concentration factor is given using the Green's function and the method of complex variable functions. First, the space is divided into upper and lower parts along the interface. In the lower half space, a suitable Green's function for the problem is constructed. It is an essential solution of the displacement field for an elastic half space with a semi-cylindrical hill of cylindrical elastic inclusion while bearing out-plane harmonic line source load at the horizontal surface. Thus, the semicircular disconnected curve can be constructed when the two parts are bonded and continuous on the interface loading the undetermined anti-plane forces on the horizontal surfaces. Also, the expressions of displacement and stress fields are obtained in this situation. Finally, examples and results of dynamic stress concentration factor are given. Influences of the cylindrical inclusion and the difference parameters of the two mediators are discussed.展开更多
Antiplane multiple curved crack problem in circular inclusion and matrix material is considered. In order to solve the proposed problem, two kinds of elementary solutions corresponding to a point screw dislocation in ...Antiplane multiple curved crack problem in circular inclusion and matrix material is considered. In order to solve the proposed problem, two kinds of elementary solutions corresponding to a point screw dislocation in inclusion and matrix material respectively are presented. Utilizing the elementary solutions and taking the density of dislocation along cracks surfaces as unknown functions, by the principle of superposition, a group of weakly singular integral equations with log kernels can be obtained. After the numerical solution of the integral equations, the discrete values of dislocation density are obtainable. So stress intensity factors at the cracks tips can be calculated, and several numerical examples are given.展开更多
This paper presents a class of Cn- continuous B- type spline curves with some paramet- ric factors.The length of their local support is equal to4.Taking the different values of the parametric factors,the curves can ...This paper presents a class of Cn- continuous B- type spline curves with some paramet- ric factors.The length of their local support is equal to4.Taking the different values of the parametric factors,the curves can become free- type curves or interpolate a set of given points even mix the both cases.When the parametric factors satisfy the certain conditions,the degrees of the curves can be decreased as low as possible.Besides,when all the parametric factors tend to zero,the curves globally approximate to the control polygon.展开更多
This paper carries out ab initio calculations to study the ^80Se2(X^3Σg^-) state and ^80Se2^+(X^2Πg), ^80Se2^+(a^4Πg) states by using completed active space self-consistent field and multi-reference second ...This paper carries out ab initio calculations to study the ^80Se2(X^3Σg^-) state and ^80Se2^+(X^2Πg), ^80Se2^+(a^4Πg) states by using completed active space self-consistent field and multi-reference second order perturbation theory. The electronic curves of these states including spin-orbit coupling are calculated, and then the spectroscopic parameters are obtained. The photoelectron spectra of ^80Se2 molecule in gas phase are assigned according to Franck-Condon analysis based on calculated potential energy curves. The ionization energies of ^80Se2 molecule are determined by the present calculation.展开更多
The weakly singular integral equation sued to solve the problem ofthe curved crack crossing the boundary of the antiplane circularinclusion is presented. Using the principal part analysis method ofthe Cauchy type inte...The weakly singular integral equation sued to solve the problem ofthe curved crack crossing the boundary of the antiplane circularinclusion is presented. Using the principal part analysis method ofthe Cauchy type integral equation, the singular stress index at theintersection and the singular stress of angular Regions near theintersection are obtained. By using the singular stress obtained, thestress intensity factor at The intersection is defined. After thenumerical solution of the integral equation, the stress intensityfactors at The end points of the crack and intersection areobtainable.展开更多
An ab initio calculations on the ground and low-lying excited statesX2∑+,2^2∑+,3^2∑+,1^4∏,2^4∏,1^4∑+,2^4∑+,and 3^4∑+of KBe molecule have been performed using multireference configuration interaction (M...An ab initio calculations on the ground and low-lying excited statesX2∑+,2^2∑+,3^2∑+,1^4∏,2^4∏,1^4∑+,2^4∑+,and 3^4∑+of KBe molecule have been performed using multireference configuration interaction (MRCI) plus Davidsoncorrections (MRCI+Q) approach with all electron basis set aug-cc-pCV5Z-DK for Be and def2-AQZVPP-JKFI for K.3^2∑+,1^4∏,2^4∏,1^4∑+,2^4∑+and3^4∑+states are investigated for the first time. Inner shell electron correlations are computed on the potential energy curves (PECs) calculations. The spectroscopic and molecular parameters are also predicted. In addition, The transition properties including transition dipole moment, Franck-Condon factors qv′v″, Einstein coefficients Av′v″, and the radiative lifetimesτ′for the2^2∑+-X2∑+,3^2∑+-X2∑+,and 2^4∏-1^4∏ transitions are predictedat the same time.展开更多
A new exact and universal conformal mapping is proposed. Using Muskhelishvili's complex potential method, the plane elasticity problem of power function curved cracks is investigated with an arbitrary power of a natu...A new exact and universal conformal mapping is proposed. Using Muskhelishvili's complex potential method, the plane elasticity problem of power function curved cracks is investigated with an arbitrary power of a natural number, and the general solutions of the stress intensity factors (SIFs) for mode I and mode II at the crack tip are obtained under the remotely uniform tensile loads. The present results can be reduced to the well-known solutions when the power of the function takes different natural numbers. Numerical examples are conducted to reveal the effects of the coefficient, the power, and the projected length along the x-axis of the power function curved crack on the SIFs for mode I and mode II.展开更多
Objective: To investigate the dissolution behavior similarity between Self-made praeparatum and reference praeparatum in different pH menstruum,using the Olanzapine Orally Disintegrating Tablets listed in abroad as th...Objective: To investigate the dissolution behavior similarity between Self-made praeparatum and reference praeparatum in different pH menstruum,using the Olanzapine Orally Disintegrating Tablets listed in abroad as the reference praeparatum. Methods: The dissolution curve of olanzapine in Self-made praeparatum and reference praeparatum was measured,the similarity of the dissolution curve was evalued by F2 similar factor. Results: The single-point dissolution of both Self-made praeparatum and reference praeparatum within 15 min was more than 85%. Conclusion: Self-made praeparatum and reference praeparatum were similar in dissolution behavior.展开更多
BACKGROUND Laparoscopic pancreaticoduodenectomy(LPD)is a surgical procedure for treating pancreatic cancer;however,the risk of complications remains high owing to the wide range of organs involved during the surgery a...BACKGROUND Laparoscopic pancreaticoduodenectomy(LPD)is a surgical procedure for treating pancreatic cancer;however,the risk of complications remains high owing to the wide range of organs involved during the surgery and the difficulty of anastomosis.Pancreatic fistula(PF)is a major complication that not only increases the risk of postoperative infection and abdominal hemorrhage but may also cause multi-organ failure,which is a serious threat to the patient’s life.This study hypothesized the risk factors for PF after LPD.AIM To identify the risk factors for PF after laparoscopic pancreatoduodenectomy in patients with pancreatic cancer.METHODS We retrospectively analyzed the data of 201 patients admitted to the Fudan University Shanghai Cancer Center between August 2022 and August 2023 who underwent LPD for pancreatic cancer.On the basis of the PF’s incidence(grades B and C),patients were categorized into the PF(n=15)and non-PF groups(n=186).Differences in general data,preoperative laboratory indicators,and surgery-related factors between the two groups were compared and analyzed using multifactorial logistic regression and receiver-operating characteristic(ROC)curve analyses.RESULTS The proportions of males,combined hypertension,soft pancreatic texture,and pancreatic duct diameter≤3 mm;surgery time;body mass index(BMI);and amylase(Am)level in the drainage fluid on the first postoperative day(Am>1069 U/L)were greater in the PF group than in the non-PF group(P<0.05),whereas the preoperative monocyte count in the PF group was lower than that in the non-PF group(all P<0.05).The logistic regression analysis revealed that BMI>24.91 kg/m²[odds ratio(OR)=13.978,95%confidence interval(CI):1.886-103.581],hypertension(OR=8.484,95%CI:1.22-58.994),soft pancreatic texture(OR=42.015,95%CI:5.698-309.782),and operation time>414 min(OR=15.41,95%CI:1.63-145.674)were risk factors for the development of PF after LPD for pancreatic cancer(all P<0.05).The areas under the ROC curve for BMI,hypertension,soft pancreatic texture,and time prediction of PF surgery were 0.655,0.661,0.873,and 0.758,respectively.CONCLUSION BMI(>24.91 kg/m²),hypertension,soft pancreatic texture,and operation time(>414 min)are considered to be the risk factors for postoperative PF.展开更多
Aim The general arbitrary cracked problem in an elastic plane was discussed. Methods For the purpose of acquiring the solution of the problem, a new formulation on the problem was proposed. Compared with the classic...Aim The general arbitrary cracked problem in an elastic plane was discussed. Methods For the purpose of acquiring the solution of the problem, a new formulation on the problem was proposed. Compared with the classical plane elastic crack model, only the known conditions were revised in the new formulation, which are greatly convenient to solve the problem, and no other new condition was given. Results and Conclusion The general exact analytic solution is given here based on the formulation though the problem is very complicated. Furthermore, the stress intensity factors K Ⅰ, K Ⅱ of the problem are also given.展开更多
To facilitate investigation of the effect of imperfect elastic dissipation on the propagation of Rayleigh-type channel waves and use of their quality factors in investigations of the properties of coal seams, a simple...To facilitate investigation of the effect of imperfect elastic dissipation on the propagation of Rayleigh-type channel waves and use of their quality factors in investigations of the properties of coal seams, a simple method for calculating the quality factor QR is proposed in this paper. Introduction of complex velocities into the dispersion function allows calculation of the dispersion function of Rayleigh-type channel waves in coal seams. By the control variable method, we analyzed changes in QR with changes in coal seam thickness and P- and S-wave Q-factors within the coal seam and adjacent rock layers. The numerical results show that the trend of the QR curve is consistent with the group velocity curve. The minimum QR value occurs at the Airy phase frequency; the Airy phase frequency decreases as coal seam thickness increases. The value of QR increases with increasing QS2(quality factor for S wave in coal seam). We can compensate for the absorption of Rayleigh-type channel waves using the computed QR curve. Inversion of the QR curve can also be used to predict the thicknesses and lithologies of coal seams.展开更多
基金Supported by the National Natural Science Foundation of China(51474109,51609090,51679097).
文摘In this study,the effects of geometrical and physical factors on light particles dispersion in stirred tank were investigated by agitation characteristic curve.The experiments and CFD simulations with discrete phase model(DPM)and volume of fluid model(VOF)were conducted in this paper.Five factors,which include four geometrical factors(submergence,impeller-to-tank ratio,number of impeller blades and baffling mode)and a physical factor(liquid viscosity)were considered.For each factor,the power consumption curve and agitation characteristic curve were drawn to compare the power consumption and mixing results in the stirred tank.Characteristics of the agitation characteristic curves were compared with the previous published literatures and theories.It is found that the agitation characteristic curves reflect the tendency of power consumption and particles distribution well in stirred tank.The good agreement indicates the applicability of the agitation characteristic curves for the study of light particles distribution in stirred tank.
基金Supported by the National Natural Science Foundation of China(51974268)the Sichuan Province Science and Technology Program(2019YJ0423)。
文摘A novel type curve is presented for oil recovery factor prediction suitable for gas flooding by innovatively introducing the equivalent water-gas cut to replace the water cut,comprehensively considering the impact of three-phase flow(oil,gas,water),and deriving the theoretical equations of gas flooding type curve based on Tong’s type curve.The equivalent water-gas cut is the ratio of the cumulative underground volume of gas and water production to the total underground volume of produced fluids.Field production data and the numerical simulation results are used to demonstrate the feasibility of the new type curve and verify the accuracy of the prediction results with field cases.The new type curve is suitable for oil recovery factor prediction of both water flooding and gas flooding.When a reservoir has no gas injected or produced,the gas phase can be ignored and only the oil and water phases need to be considered,in this case,this gas flooding type curve returns to the Tong’s type curve,which can evaluate the oil recovery factor of water flooding.For reservoirs with equivalent water-gas cuts of 60%-80%,the regression method of the new type curve works well in predicting the oil recovery factor.For reservoirs with equivalent water-gas cuts higher than 80%,both the regression and assignment methods of the new type curve can accurately predict the oil recovery factor of gas flooding.
文摘Although high-dose methotrexate(HD-MTX)is the most effective drug against primary CNS lymphomas(PCNSL),outcome-de-termining variables related to its administration schedule have not been defined.The impact on toxicity and outcome of the area under thecurve(AUC(MTX)),dose intensity(DI(MTX))and infusion rate(IR(MTX))of MTX and plsamatic creatinine clearance(CL(crea))was investigated in a retrospective series of 45 PCNSL patients treated with three different HD-MTX-basedcombinations.Anticon-vulsants were administered in 31 pts(69%).Age>60 years,anticonvulsant therapy,slow IR(MTX)(</=800 mgm(-2)h(-1)),and reduced DI(MTX)(</=1000 mgm(-2)wk(-1))were significantly correlated with low AUC(MTX)values.Seven pa-
文摘By adopting the method of controlling parameters this paper describes the construction of various kinds of cubic curve segment and curved surface fragment with rational and non rational parameters, and discusses the relationship between controlling parameters, weighted factors and types, kinds and characteristics of curve segments and curved surface fragments. A mathematical method is provided for CAGD with abundant connotations, broad covering region, convenience, flexibility and direct simplicity.
文摘Horizontal alignment greatly affects the speedof vehicles at rural roads. Therefore, it is necessary toanalyze and predict vehicles speed on curve sections.Numerous studies took rural two-lane as research subjectsand provided models for predicting operating speeds.However, less attention has been paid to multi-lane highwaysespecially in Egypt. In this research, field operatingspeed data of both cars and trucks on 78 curve sections offour multi-lane highways is collected. With the data, correlationbetween operating speed (V85) and alignment isanalyzed. The paper includes two separate relevant analyses.The first analysis uses the regression models toinvestigate the relationships between V85 as dependentvariable, and horizontal alignment and roadway factors asindependent variables. This analysis proposes two predictingmodels for cars and trucks. The second analysisuses the artificial neural networks (ANNs) to explore theprevious relationships. It is found that the ANN modelinggives the best prediction model. The most influential variableon V85 for cars is the radius of curve. Also, for V85 fortrucks, the most influential variable is the median width.Finally, the derived models have statistics within theacceptable regions and they are conceptually reasonable.
基金Supported by the National Natural Science Foun-dation of China (2001AA141010)
文摘We prove all integral points of the elliptic curve y^2=x^2-30x+133 are (x,y) = (-7,0),(-3,±14),(2, ±9),(6,±13), (5143326,±11664498677), by using the method of algebraic number theory and p-adic analysis. Furthermore, we develop a computation method to find all integral points on a class of elliptic curve y^2= (x+α)(x^2-α)(x^2-αx+b) ,α ,b∈Z,α^2〈4b and find all integer solutions of hyperelliptic Diophantine equation Dy^2=Ax^4 + Bx^2 +C,B^2〈4AC.
基金Project supported by the Natural Science Foundation of Heilongjiang Province (No.A0206)
文摘Scattering of SH wave from an interface cylindrical elastic inclusion with a semicircular disconnected curve is investigated. The solution of dynamic stress concentration factor is given using the Green's function and the method of complex variable functions. First, the space is divided into upper and lower parts along the interface. In the lower half space, a suitable Green's function for the problem is constructed. It is an essential solution of the displacement field for an elastic half space with a semi-cylindrical hill of cylindrical elastic inclusion while bearing out-plane harmonic line source load at the horizontal surface. Thus, the semicircular disconnected curve can be constructed when the two parts are bonded and continuous on the interface loading the undetermined anti-plane forces on the horizontal surfaces. Also, the expressions of displacement and stress fields are obtained in this situation. Finally, examples and results of dynamic stress concentration factor are given. Influences of the cylindrical inclusion and the difference parameters of the two mediators are discussed.
文摘Antiplane multiple curved crack problem in circular inclusion and matrix material is considered. In order to solve the proposed problem, two kinds of elementary solutions corresponding to a point screw dislocation in inclusion and matrix material respectively are presented. Utilizing the elementary solutions and taking the density of dislocation along cracks surfaces as unknown functions, by the principle of superposition, a group of weakly singular integral equations with log kernels can be obtained. After the numerical solution of the integral equations, the discrete values of dislocation density are obtainable. So stress intensity factors at the cracks tips can be calculated, and several numerical examples are given.
文摘This paper presents a class of Cn- continuous B- type spline curves with some paramet- ric factors.The length of their local support is equal to4.Taking the different values of the parametric factors,the curves can become free- type curves or interpolate a set of given points even mix the both cases.When the parametric factors satisfy the certain conditions,the degrees of the curves can be decreased as low as possible.Besides,when all the parametric factors tend to zero,the curves globally approximate to the control polygon.
基金supported by the National Natural Science Foundation of China (Grant No 10604022)
文摘This paper carries out ab initio calculations to study the ^80Se2(X^3Σg^-) state and ^80Se2^+(X^2Πg), ^80Se2^+(a^4Πg) states by using completed active space self-consistent field and multi-reference second order perturbation theory. The electronic curves of these states including spin-orbit coupling are calculated, and then the spectroscopic parameters are obtained. The photoelectron spectra of ^80Se2 molecule in gas phase are assigned according to Franck-Condon analysis based on calculated potential energy curves. The ionization energies of ^80Se2 molecule are determined by the present calculation.
基金National Natural Science Foundation of China(No.59879012)the project of Chinese Foundation of State Education Commission(No.98024832)
文摘The weakly singular integral equation sued to solve the problem ofthe curved crack crossing the boundary of the antiplane circularinclusion is presented. Using the principal part analysis method ofthe Cauchy type integral equation, the singular stress index at theintersection and the singular stress of angular Regions near theintersection are obtained. By using the singular stress obtained, thestress intensity factor at The intersection is defined. After thenumerical solution of the integral equation, the stress intensityfactors at The end points of the crack and intersection areobtainable.
基金Project supported by the National Natural Science Foundation of China(Grant No.11647075)the Scientific Research Fund of Sichuan Provincial Education Department,China(Grant No.14ZB0284)the Scientific Research Key Project of Yibin University,China(Grant No.2013QD09)
文摘An ab initio calculations on the ground and low-lying excited statesX2∑+,2^2∑+,3^2∑+,1^4∏,2^4∏,1^4∑+,2^4∑+,and 3^4∑+of KBe molecule have been performed using multireference configuration interaction (MRCI) plus Davidsoncorrections (MRCI+Q) approach with all electron basis set aug-cc-pCV5Z-DK for Be and def2-AQZVPP-JKFI for K.3^2∑+,1^4∏,2^4∏,1^4∑+,2^4∑+and3^4∑+states are investigated for the first time. Inner shell electron correlations are computed on the potential energy curves (PECs) calculations. The spectroscopic and molecular parameters are also predicted. In addition, The transition properties including transition dipole moment, Franck-Condon factors qv′v″, Einstein coefficients Av′v″, and the radiative lifetimesτ′for the2^2∑+-X2∑+,3^2∑+-X2∑+,and 2^4∏-1^4∏ transitions are predictedat the same time.
基金supported by the National Natural Science Foundation of China(Nos.10932001,11072015, and 10761005)the Scientific Research Key Program of Beijing Municipal Commission of Education (No.KZ201010005003)+1 种基金the Specialized Research Fund for the Doctoral Program of Higher Education of China(No.20101102110016)the Ph.D.Innovation Foundation of Beijing University of Aeronautics and Astronautics(No.300351)
文摘A new exact and universal conformal mapping is proposed. Using Muskhelishvili's complex potential method, the plane elasticity problem of power function curved cracks is investigated with an arbitrary power of a natural number, and the general solutions of the stress intensity factors (SIFs) for mode I and mode II at the crack tip are obtained under the remotely uniform tensile loads. The present results can be reduced to the well-known solutions when the power of the function takes different natural numbers. Numerical examples are conducted to reveal the effects of the coefficient, the power, and the projected length along the x-axis of the power function curved crack on the SIFs for mode I and mode II.
文摘Objective: To investigate the dissolution behavior similarity between Self-made praeparatum and reference praeparatum in different pH menstruum,using the Olanzapine Orally Disintegrating Tablets listed in abroad as the reference praeparatum. Methods: The dissolution curve of olanzapine in Self-made praeparatum and reference praeparatum was measured,the similarity of the dissolution curve was evalued by F2 similar factor. Results: The single-point dissolution of both Self-made praeparatum and reference praeparatum within 15 min was more than 85%. Conclusion: Self-made praeparatum and reference praeparatum were similar in dissolution behavior.
文摘BACKGROUND Laparoscopic pancreaticoduodenectomy(LPD)is a surgical procedure for treating pancreatic cancer;however,the risk of complications remains high owing to the wide range of organs involved during the surgery and the difficulty of anastomosis.Pancreatic fistula(PF)is a major complication that not only increases the risk of postoperative infection and abdominal hemorrhage but may also cause multi-organ failure,which is a serious threat to the patient’s life.This study hypothesized the risk factors for PF after LPD.AIM To identify the risk factors for PF after laparoscopic pancreatoduodenectomy in patients with pancreatic cancer.METHODS We retrospectively analyzed the data of 201 patients admitted to the Fudan University Shanghai Cancer Center between August 2022 and August 2023 who underwent LPD for pancreatic cancer.On the basis of the PF’s incidence(grades B and C),patients were categorized into the PF(n=15)and non-PF groups(n=186).Differences in general data,preoperative laboratory indicators,and surgery-related factors between the two groups were compared and analyzed using multifactorial logistic regression and receiver-operating characteristic(ROC)curve analyses.RESULTS The proportions of males,combined hypertension,soft pancreatic texture,and pancreatic duct diameter≤3 mm;surgery time;body mass index(BMI);and amylase(Am)level in the drainage fluid on the first postoperative day(Am>1069 U/L)were greater in the PF group than in the non-PF group(P<0.05),whereas the preoperative monocyte count in the PF group was lower than that in the non-PF group(all P<0.05).The logistic regression analysis revealed that BMI>24.91 kg/m²[odds ratio(OR)=13.978,95%confidence interval(CI):1.886-103.581],hypertension(OR=8.484,95%CI:1.22-58.994),soft pancreatic texture(OR=42.015,95%CI:5.698-309.782),and operation time>414 min(OR=15.41,95%CI:1.63-145.674)were risk factors for the development of PF after LPD for pancreatic cancer(all P<0.05).The areas under the ROC curve for BMI,hypertension,soft pancreatic texture,and time prediction of PF surgery were 0.655,0.661,0.873,and 0.758,respectively.CONCLUSION BMI(>24.91 kg/m²),hypertension,soft pancreatic texture,and operation time(>414 min)are considered to be the risk factors for postoperative PF.
文摘Aim The general arbitrary cracked problem in an elastic plane was discussed. Methods For the purpose of acquiring the solution of the problem, a new formulation on the problem was proposed. Compared with the classical plane elastic crack model, only the known conditions were revised in the new formulation, which are greatly convenient to solve the problem, and no other new condition was given. Results and Conclusion The general exact analytic solution is given here based on the formulation though the problem is very complicated. Furthermore, the stress intensity factors K Ⅰ, K Ⅱ of the problem are also given.
基金This work is supported by the National Natural Science Foundation of China (No. 41140033).
文摘To facilitate investigation of the effect of imperfect elastic dissipation on the propagation of Rayleigh-type channel waves and use of their quality factors in investigations of the properties of coal seams, a simple method for calculating the quality factor QR is proposed in this paper. Introduction of complex velocities into the dispersion function allows calculation of the dispersion function of Rayleigh-type channel waves in coal seams. By the control variable method, we analyzed changes in QR with changes in coal seam thickness and P- and S-wave Q-factors within the coal seam and adjacent rock layers. The numerical results show that the trend of the QR curve is consistent with the group velocity curve. The minimum QR value occurs at the Airy phase frequency; the Airy phase frequency decreases as coal seam thickness increases. The value of QR increases with increasing QS2(quality factor for S wave in coal seam). We can compensate for the absorption of Rayleigh-type channel waves using the computed QR curve. Inversion of the QR curve can also be used to predict the thicknesses and lithologies of coal seams.