P-arsanilic acid(p-ASA),as a kind of organoarsenic feed additive,has been widely used in poultry and swine breeding.However,it has caused the arsenic pollution around the farm.Currently data shows humic acid(HA)is clo...P-arsanilic acid(p-ASA),as a kind of organoarsenic feed additive,has been widely used in poultry and swine breeding.However,it has caused the arsenic pollution around the farm.Currently data shows humic acid(HA)is closely to the migration and transformation of p-ASA.Therefore,the interaction between p-ASA and HA was investigated by using the method of fluorescence quenching titration.The association constant changed from2.74 to 4.88 L·mol-1at a p H varying from 5 to 9 and reached the maximum at p H 7.In addition,log K varied from4.15 to 5.02 L·mol-1when the temperature increased from 15℃to 35℃.The log K increased with an increase in the concentration of HA.The dominant mechanism between p-ASA and HA is static quenching.The primary interaction force was likely the hydrogen bond,and the binding behavior occurred on the As-O stretch of p-ASA and the carboxylic acid C=O stretch of HA.The results showed that dissolved organic matters could affect the fate and biogeochemical cycling of organoarsenic pharmaceuticals in aquatic ecosystems.展开更多
探讨衰弱筛查量表(the FRAIL scale)联合ASA分级(American Society of Anesthesiologists)对老年人关节置换术后并发症的预测作用。方法 收集我院行椎管内麻醉接受关节置换手术的115例年龄>65岁患者的一般资料、麻醉分级,采用衰弱筛...探讨衰弱筛查量表(the FRAIL scale)联合ASA分级(American Society of Anesthesiologists)对老年人关节置换术后并发症的预测作用。方法 收集我院行椎管内麻醉接受关节置换手术的115例年龄>65岁患者的一般资料、麻醉分级,采用衰弱筛查量表评估患者术前衰弱状态,记录并比较患者手术时长、术中出血量、术后在院的时间长短、术后24小时和48小时的疼痛情况以及住院期间并发症的发生情况。通过收集以上数据,采用受试者工作特征曲线(receiver operating characteristic,ROC),比较并评价ASA分级、衰弱筛查量表二者联合应用和两种方式单独应用,对老年患者关节置换术后并发症的预测作用。结果 单独应用ASA分级和衰弱筛查量表预测老年患者关节置换术后并发症的AUC(area under the curve,曲线下面积)分别为0.635和 0.671, ASA分级和衰弱筛查量表联合应用预测老年患者关节置换术后并发症的AUC为0.726,该结果表明对于预测老年患者关节置换术后并发症的能力联合应用ASA分级和衰弱筛查量表优于单独应用ASA分级或单独应用衰弱筛查量表。结论 在术前对需行关节置换的老年患者的评估中,采用衰弱筛查量表联合ASA分级评估比单独应用ASA分级或单独应用衰弱评估对术后并发症的预测更为准确。展开更多
随着口腔种植技术的普及,如何能够安全的为全身复杂系统疾病患者实施种植手术是当下种植医生不得不面临的挑战。根据患者身体状况,美国麻醉医师协会(American Society of Anesthesiologists,ASA)将围手术期风险进行分级,ASAⅠ~Ⅱ级的患...随着口腔种植技术的普及,如何能够安全的为全身复杂系统疾病患者实施种植手术是当下种植医生不得不面临的挑战。根据患者身体状况,美国麻醉医师协会(American Society of Anesthesiologists,ASA)将围手术期风险进行分级,ASAⅠ~Ⅱ级的患者手术风险极低,ASAⅣ级以上的患者风险极高,不适合手术。对于ASAⅢ级患者,如何评估围手术期风险、实施种植外科手术、降低围手术期严重并发症是越来越多种植医生关注的问题。本文拟从临床最常见合并心血管疾病的ASAⅢ级患者入手,探讨此类患者口腔种植手术的风险评估、防范及并发症防治,为该类患者安全进行种植修复提供参考。展开更多
基金National Natural Science Foundation of China(41373111)
文摘P-arsanilic acid(p-ASA),as a kind of organoarsenic feed additive,has been widely used in poultry and swine breeding.However,it has caused the arsenic pollution around the farm.Currently data shows humic acid(HA)is closely to the migration and transformation of p-ASA.Therefore,the interaction between p-ASA and HA was investigated by using the method of fluorescence quenching titration.The association constant changed from2.74 to 4.88 L·mol-1at a p H varying from 5 to 9 and reached the maximum at p H 7.In addition,log K varied from4.15 to 5.02 L·mol-1when the temperature increased from 15℃to 35℃.The log K increased with an increase in the concentration of HA.The dominant mechanism between p-ASA and HA is static quenching.The primary interaction force was likely the hydrogen bond,and the binding behavior occurred on the As-O stretch of p-ASA and the carboxylic acid C=O stretch of HA.The results showed that dissolved organic matters could affect the fate and biogeochemical cycling of organoarsenic pharmaceuticals in aquatic ecosystems.
文摘探讨衰弱筛查量表(the FRAIL scale)联合ASA分级(American Society of Anesthesiologists)对老年人关节置换术后并发症的预测作用。方法 收集我院行椎管内麻醉接受关节置换手术的115例年龄>65岁患者的一般资料、麻醉分级,采用衰弱筛查量表评估患者术前衰弱状态,记录并比较患者手术时长、术中出血量、术后在院的时间长短、术后24小时和48小时的疼痛情况以及住院期间并发症的发生情况。通过收集以上数据,采用受试者工作特征曲线(receiver operating characteristic,ROC),比较并评价ASA分级、衰弱筛查量表二者联合应用和两种方式单独应用,对老年患者关节置换术后并发症的预测作用。结果 单独应用ASA分级和衰弱筛查量表预测老年患者关节置换术后并发症的AUC(area under the curve,曲线下面积)分别为0.635和 0.671, ASA分级和衰弱筛查量表联合应用预测老年患者关节置换术后并发症的AUC为0.726,该结果表明对于预测老年患者关节置换术后并发症的能力联合应用ASA分级和衰弱筛查量表优于单独应用ASA分级或单独应用衰弱筛查量表。结论 在术前对需行关节置换的老年患者的评估中,采用衰弱筛查量表联合ASA分级评估比单独应用ASA分级或单独应用衰弱评估对术后并发症的预测更为准确。
文摘随着口腔种植技术的普及,如何能够安全的为全身复杂系统疾病患者实施种植手术是当下种植医生不得不面临的挑战。根据患者身体状况,美国麻醉医师协会(American Society of Anesthesiologists,ASA)将围手术期风险进行分级,ASAⅠ~Ⅱ级的患者手术风险极低,ASAⅣ级以上的患者风险极高,不适合手术。对于ASAⅢ级患者,如何评估围手术期风险、实施种植外科手术、降低围手术期严重并发症是越来越多种植医生关注的问题。本文拟从临床最常见合并心血管疾病的ASAⅢ级患者入手,探讨此类患者口腔种植手术的风险评估、防范及并发症防治,为该类患者安全进行种植修复提供参考。
