Stereoslective Synthesis of (Z)-1, 2-Bis(arylseleno)-1-alkene by Addition of Cesium Arylselenolate to Alkynyl Selenide

Alkynyl selenide reacted with cesium arylselenolate in commercial THF at r.t under N2 to afford (Z)-1, 2-bis(arylseleno)-1-alkene in high yields.

Regioselective Ring-opening Reaction of 1,2-Epoxides with Arylselenol under Solvent-free Conditions and Application to the Synthesis of 1,3-Oxazolidin-2-ones

Regioselective ring-opening reactions of 1,2-epoxides with ArSeH catalyzed by Ti（O^tPr）4 under solvent-free conditions were investigated. A variety of β-hydroxyselenides were obtained in excellent yields of 90%-97% and regioselectivities by a simple, atom economic and environment-friendly procedure. Several N-tosyl- 1,3-oxazolidin-2-ones were prepared starting from the corresponding 1,2-epoxides and ArSeH by a one-pot three-step procedure.

芳硒化铯与炔硒醚反应合成(Z)-1,2-二芳硒基烯

芳硒化钠与炔硒醚在室温不反应.但是,在室温、氮气保护下芳硒化铯与炔硒醚能有效的进行反应,立体选择生成(Z) 1,2 二芳硒基烯,产率在88%～95%.这表明ArSeCs中ArSe-具有较强的亲核性.本方法具有反应条件温和、产率高、不需无水条件、实验操作简单.这一方法为(Z) 1,2 二芳硒基烯的合成提供了一条新的有效的途径.

氯化铯催化硒酚烷基化反应合成不对称硒醚

通过卤代烃与硒酚反应合成了不对称硒醚，至少要使用等摩尔的氢氧化铯作碱，与氢氧化钾相比，氯化铯价格昂贵。本文研究用计量的氢氧化钾作催化剂，实验表明，在无水DMF中，4A分子筛存在下，烷基卤、溴代乙酸乙酯、苄基溴及烯丙溴与芳硒酚在室温能有效反应，得到不对称硒醚，收率78％-95％。以苯硒酚（0．1mol）与溴乙烷（0．3mol）反应为例的放大实验，产物苯基乙基硒醚的收率为90．2％。

氯化锌催化硒酚对环氧化合物开环反应合成β-羟基硒醚

研究了在室温下ZnCl2催化硒酚对环氧化合物开环反应合成β-羟基硒醚.通过这一简单、有效和原子经济性的反应,高收率和高选择性地合成了几种β-羟基硒醚.从环氧化合物3-邻甲苯氧基-1,2-环氧丙烷出发,经一锅三步反应,合成了相应的1,3-口恶唑-2-酮.