The production,transport and integration of myelin components into the membrane during development is a highly coordinated and regulated process that relies heavily on the endoplasmic reticulum(ER),a sub-cellular or...The production,transport and integration of myelin components into the membrane during development is a highly coordinated and regulated process that relies heavily on the endoplasmic reticulum(ER),a sub-cellular organelle that is the principal site of membrane assembly.Ribosomes on the rough ER allow translation of proteins such as proteolipid protein(PLP)prior to correct folding,展开更多
文摘The production,transport and integration of myelin components into the membrane during development is a highly coordinated and regulated process that relies heavily on the endoplasmic reticulum(ER),a sub-cellular organelle that is the principal site of membrane assembly.Ribosomes on the rough ER allow translation of proteins such as proteolipid protein(PLP)prior to correct folding,