Recent progress of sugar amino acids: Synthetic strategies and applications as glycomimetics and peptidomimetics

In order to meet the increasing demands for the development of large varieties of new molecules for discovering new drugs and materials, organic chemists are developing many novel multifunctional building blocks, which are assembled rationally to create ‘nature-like＇ and yet unnatural organic molecules with well-defined structures and useful properties. Sugar amino acids（SAAs）, the carbohydrate derivatives bearing both amino and carboxylic acid functional groups, are important ones of these multifunctional building blocks, which can be used to create novel materials with potential applications as glycomimetics and peptidomimetics. This review will focus on recent synthetic strategies of SAAs and their applications in creating large number of structurally diverse glycomimetics and peptidomimetics.

The design of the superconducting wiggler power supply system for HEPS-TF

Purpose This paper describes the design of power supply system for superconducting wiggler in the project of high energy photon source-test facility.It includes three sets of high precision DC stabilized current power supplies for superconducting magnet excitation and three sets of quench protection assembly(QPA).A special magnetic load which has a very large time constant is studied in this paper.In this paper,a stable superconducting excitation power supply is developed,which can adjust the response quickly under the condition of very large load time constant.Meanwhile,the energy dissipation circuit of the QPA is integrated into the power supply in an active quenching protection mode to accelerate the energy release of the superconducting magnet and protect the superconducting magnet.Method The main circuit topology,control algorithm,quenching protection circuit and interlocking logic function are designed for the superconducting magnet with large inductance.The upper computer controls the switch of the three main power circuits through the serial port,sets the output current and adjusts the parameters according to the load.Conclusion Through a series of scientific and rigorous experiments,the rationality of superconducting wiggler magnet power supply scheme is demonstrated.The output current stability test and output voltage ripple test of the power supply meet or exceed the requirements of the magnet system.