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An Analysis of Therapeutic Effect of Drug Acupoint Application in 209 Cases of Allergic Asthma 被引量:3
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作者 赖新生 李月梅 +2 位作者 范兆金 张家维 刘炳权 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第2期122-126,共5页
Both therapies of traditional crude herb moxibustion and drug acupoint application were used in 209 cases of allergic asthma to compare their long-term and short-term therapeutic effects and to analyze the relationshi... Both therapies of traditional crude herb moxibustion and drug acupoint application were used in 209 cases of allergic asthma to compare their long-term and short-term therapeutic effects and to analyze the relationship between clinic therapeutic effects of both therapies and differential types of the disease. The results showed that the short-term total effective rate in the group of drug acupoint application was higher than that in the group of traditional crude herb moxibustion, the therapeutic effects of drug acupoint application being closely related to differential types. Analysis also shows the best short-term therapeutic effect was in the type of heat in the lung while the poorest effect in the type of deficiency of the kidney-yang. 展开更多
关键词 Acupuncture Points MOXIBUSTION asthma Diagnosis Differential drugs Chinese Herbal FEMALE Humans MALE Medicine Chinese Traditional
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A Report for the Therapeutic Effects of Asthma Plaster in the Treatment of 139 Asthmatic Children
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作者 刘贵云 向华林 +3 位作者 米仁贤 黄利莎 王青 缪卫群 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第4期261-262,共2页
In June 1994, asthma plaster was developed, which has proved effective in the treatment of cold-type asthma by applying it on some acupoints, which are known to be good for asthma.
关键词 ACUPRESSURE Acupuncture Points ADOLESCENT asthma CHILD Child Preschool drugs Chinese Herbal Female Humans Male
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The Guiding Role of Pharmaceutical Care in the Rational Drug Use of Bronchial Asthma
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作者 Hongmei Chen 《Journal of Integrative Medicine(双语)》 2019年第1期23-26,共4页
Objective:To investigate the guiding role of pharmaceutical care in the treatment of bronchial asthma.Methods:Eighty patients with bronchial disease admitted to our hospital from November 2008 to December 1818 were en... Objective:To investigate the guiding role of pharmaceutical care in the treatment of bronchial asthma.Methods:Eighty patients with bronchial disease admitted to our hospital from November 2008 to December 1818 were enrolled in this research.The computer program was used to generate random numbers.The method was divided into two groups:control group and observation group,40 cases respectively.40 patients in the control group were treated with normal medication according to the doctor’s advice;40 patients in the observation group were enrolled in the pharmacological care on the basis of the control group,and the rational drug use was compared between the two groups.Results:The incidence of adverse reactions in the observation group and the control group were 5.00%and 17.50%,respectively,and the difference was statistically significant(P<0.05);the incidence of medication error events in the observation group was 7.50%,which was significantly lower than that of the control group,which was 25.00%,and the difference was statistically significant(P<0.05).The medication errors mainly include improper administration,incorrect dosage,and unscientific administration.Conclusion:The guiding role of pharmaceutical care in bronchial asthma rational drug use can reduce medication error events and ensure rational drug use,which is worthy of popularization in clinical practice. 展开更多
关键词 Pharmaceutical care Bronchial asthma Rational drug use ROLE
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TREATMENT OF 42 CASES OF ASTHMA WITH ACUPUNCTURE PLUS DRUG-CAKE MOXIBUSTION
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作者 高远丽 《World Journal of Acupuncture-Moxibustion》 1999年第3期49-51,共3页
In the present paper, 42 cases of asthma patients were treated with acupuncture anddrug-cake moxibustion at Dazhui (GV 14), Feishu (BL 13), Jueyinshu (BL 14), etc.. After treatment, of the 42 cases, 10 (23. 8 % ) had ... In the present paper, 42 cases of asthma patients were treated with acupuncture anddrug-cake moxibustion at Dazhui (GV 14), Feishu (BL 13), Jueyinshu (BL 14), etc.. After treatment, of the 42 cases, 10 (23. 8 % ) had controlled their symptoms, 15 (35. 7 % ) experienced markedimprovement, l3 (31. 0 % ) had improvement and 4 (9. 5 % ) had not any effect, with the effectiverate of 90. 5 %. 展开更多
关键词 asthma ACUPUNCTURE therapy drug-cake MOXIBUSTION
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儿童支气管哮喘的药物治疗研究进展
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作者 鲁思琪 王雅妮 +3 位作者 陈海 李玉勤 卢红艳 常明 《医学综述》 CAS 2024年第11期1394-1398,共5页
支气管哮喘是儿科常见呼吸系统疾病,严重危害儿童身心健康、生活质量,甚至危及生命。目前,临床上对于儿童支气管哮喘常选用药物治疗,以达到缓解病痛、抑制病情持续恶化的目的。其常用药物主要分为两类,一类是控制性药物,一类是缓解性药... 支气管哮喘是儿科常见呼吸系统疾病,严重危害儿童身心健康、生活质量,甚至危及生命。目前,临床上对于儿童支气管哮喘常选用药物治疗,以达到缓解病痛、抑制病情持续恶化的目的。其常用药物主要分为两类,一类是控制性药物,一类是缓解性药物,分别通过不同的方式产生相应功效,从而平稳地控制病情发展,提高患儿的生活质量。随着临床对儿童支气管哮喘的深入研究,未来其药物的利用将越来越合理化,并研发出各种新药。 展开更多
关键词 支气管哮喘 儿童 药物 治疗情况
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中药药对治疗小儿咳嗽变异性哮喘的临床研究 被引量:1
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作者 周颖 朱浩宇 《中国中西医结合儿科学》 2024年第3期197-200,共4页
长久以来,反复发作迁延难愈的小儿咳嗽都是困扰无数家长和医者的医学难题,药对配伍理念作为祖国医学特色治疗手段之一,在临床中发挥着举足轻重的作用。现通过研究发汗解表之麻黄-桂枝、疏风清肺之桑叶-菊花、理气化痰之陈皮-半夏、养阴... 长久以来,反复发作迁延难愈的小儿咳嗽都是困扰无数家长和医者的医学难题,药对配伍理念作为祖国医学特色治疗手段之一,在临床中发挥着举足轻重的作用。现通过研究发汗解表之麻黄-桂枝、疏风清肺之桑叶-菊花、理气化痰之陈皮-半夏、养阴润肺之天冬-麦冬、温肺止咳之五味子-干姜、和解少阳之柴胡-黄芩以及益气健脾之党参-黄芪七对药对,以期更好地发挥中医的特色优势,为临床治疗小儿咳嗽变异性哮喘提供新的思路。 展开更多
关键词 咳嗽变异性哮喘 常用药对 配伍 儿童
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生物靶向药物在哮喘气道黏液栓治疗中的价值
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作者 牟朵 刘可欣 常春 《中国临床药理学与治疗学》 CAS CSCD 北大核心 2024年第4期423-426,共4页
气道黏液栓是哮喘中常见的一种表型,通过引起气流阻塞加重而使哮喘急性发作风险增高。鉴于其在哮喘中的重要作用,针对气道黏液栓的治疗或将成为控制哮喘进展、预防或解除致死性哮喘发作的策略。既往研究表明,嗜酸粒细胞、T2型炎症等与... 气道黏液栓是哮喘中常见的一种表型,通过引起气流阻塞加重而使哮喘急性发作风险增高。鉴于其在哮喘中的重要作用,针对气道黏液栓的治疗或将成为控制哮喘进展、预防或解除致死性哮喘发作的策略。既往研究表明,嗜酸粒细胞、T2型炎症等与黏液栓的形成有关,针对上述通路的生物靶向药物可能在治疗气道黏液栓方面发挥疗效。 展开更多
关键词 气道黏液栓 哮喘 生物靶向药物
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茶碱类药物在喘息性疾病中的应用进展
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作者 朱晓燕 刘辉国 《医学综述》 CAS 2024年第8期983-989,共7页
喘息性疾病指包括哮喘、慢性阻塞性肺疾病等临床以喘息为主要症状的一组疾病,在呼吸系统疾病中发病率较高。茶碱类药物作为临床常见的一类平喘药物,在抑制炎症反应、调节免疫、促进细胞凋亡、激活组蛋白脱乙酰酶等方面发挥作用。茶碱类... 喘息性疾病指包括哮喘、慢性阻塞性肺疾病等临床以喘息为主要症状的一组疾病,在呼吸系统疾病中发病率较高。茶碱类药物作为临床常见的一类平喘药物,在抑制炎症反应、调节免疫、促进细胞凋亡、激活组蛋白脱乙酰酶等方面发挥作用。茶碱类药物种类繁多,主要有茶碱、氨茶碱、二羟丙茶碱和多索茶碱,且茶碱类药物价格低廉,在喘息性疾病的治疗上有确切的疗效。随着茶碱不同制剂的推出,选择合适的制剂既可以保持疗效,还能减少副作用的发生。未来将有更多疗效确切、价格低廉的茶碱类药物应用于临床。 展开更多
关键词 哮喘 茶碱类药物 氨茶碱 口服溶液
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抗免疫球蛋白E药物在儿童哮喘中的合理应用
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作者 陈静 向莉 《中国合理用药探索》 CAS 2024年第8期60-64,共5页
儿童哮喘作为一种常见的慢性呼吸道疾病,对患儿的生活质量及家庭负担造成了严重影响。近年来,抗免疫球蛋白E(IgE)药物作为治疗儿童哮喘的新型生物制剂,其疗效和安全性得到了广泛关注。本文综述了抗IgE药物在儿童哮喘治疗中的研究进展,... 儿童哮喘作为一种常见的慢性呼吸道疾病,对患儿的生活质量及家庭负担造成了严重影响。近年来,抗免疫球蛋白E(IgE)药物作为治疗儿童哮喘的新型生物制剂,其疗效和安全性得到了广泛关注。本文综述了抗IgE药物在儿童哮喘治疗中的研究进展,包括作用机制、药物特性、临床应用及与其他治疗药物的联合应用等,旨在探讨抗IgE药物在儿童哮喘中的合理应用策略及治疗展望,以期为临床实践提供参考。 展开更多
关键词 儿童哮喘 治疗 生物制剂 抗IgE药物 合理应用
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清气化痰丸加减联合丙卡特罗治疗痰热蕴肺证支气管哮喘的临床效果及对炎性因子的影响
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作者 观云 武蕾 +1 位作者 彭飞飞 张萱 《临床误诊误治》 CAS 2024年第14期74-78,共5页
目的评价清气化痰丸加减联合丙卡特罗治疗痰热蕴肺证支气管哮喘的临床效果。方法选取2022年1月至2023年12月收治的130例痰热蕴肺证支气管哮喘患者,采用随机数字表法分为观察组、对照组各65例,对照组采用丙卡特罗颗粒,观察组在对照组基... 目的评价清气化痰丸加减联合丙卡特罗治疗痰热蕴肺证支气管哮喘的临床效果。方法选取2022年1月至2023年12月收治的130例痰热蕴肺证支气管哮喘患者,采用随机数字表法分为观察组、对照组各65例,对照组采用丙卡特罗颗粒,观察组在对照组基础上加服清气化痰丸加减方,2组均服用14 d。观察2组患者临床疗效,治疗前后中医症候积分、肺功能指标[第1秒用力呼气容积(FEV1)、FEV1/用力肺活量(FVC)、最大呼气流量(PEF)]、炎性因子[白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、免疫球蛋白E(IgE)]、免疫指标(CD3+、CD4+、CD8+、CD4+/CD8+)水平,以及不良反应发生情况。结果治疗后,观察组总有效率为90.77%高于对照组的7385%(P<0.05)。治疗后,2组中医证候积分较治疗前降低,且观察组低于对照组(P<0.05,P<001)。治疗后2组FEV1/FVC、FEV1、PEF均上升,且观察组FEV1/FVC、FEV1、PEF改善更显著(P<0.05,P<001)。治疗后2组IL-6、IL-8、IgE水平均较前降低,且观察组改善更显著(P<0.05,P<001)。治疗后2组CD3+、CD4+、CD4+/CD8+水平升高,CD8+水平降低,且观察组上述指标变化较对照组明显(P<0.05,P<001)。2组治疗期间均未见不良反应发生。结论采用清气化痰丸加减方联合丙卡特罗治疗痰热蕴肺证支气管哮喘患者有较好的效果,能够明显改善患者临床症状、肺功能、免疫功能,减轻气道炎症,且具有较好的安全性。 展开更多
关键词 支气管哮喘 痰热蕴肺 清气化痰丸 第1秒用力呼气容积 白细胞介素-6 CD3+ 药物毒性
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经典Wnt/β-catenin信号在过敏性哮喘中的功能研究进展
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作者 刘胜男 王文静 +1 位作者 张欢欢 伊淑莹 《中国免疫学杂志》 CAS CSCD 北大核心 2024年第9期1964-1968,共5页
过敏性哮喘是一种复杂的呼吸系统异质性疾病,在遗传水平上具有广泛的变异性,并有多种机会改变遗传多样性。越来越多的研究表明,靶向Wnt/β-catenin信号途径可以影响过敏性哮喘的发生发展,但其具体免疫性作用机制尚不明确。本文主要通过... 过敏性哮喘是一种复杂的呼吸系统异质性疾病,在遗传水平上具有广泛的变异性,并有多种机会改变遗传多样性。越来越多的研究表明,靶向Wnt/β-catenin信号途径可以影响过敏性哮喘的发生发展,但其具体免疫性作用机制尚不明确。本文主要通过介绍Wnt/β-catenin信号及其在过敏性哮喘中的作用和功能,为治疗过敏性哮喘的药物干预提供新靶点。 展开更多
关键词 过敏性哮喘 Wnt/β-catenin信号 免疫 药物干预
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新型抗嗜酸性粒细胞药物在哮喘中应用的研究进展
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作者 褚小娟 杨文婷 +4 位作者 唐连涛 李向魁 付臣昆 田鑫 程义局 《中国医药》 2024年第6期924-927,共4页
哮喘是当今世界上常见的慢性非传染性疾病之一,其特征是可变的气体阻塞,引起呼吸困难和喘息。嗜酸性粒细胞性气道炎症通常被视为慢性气道病变最具影响力的可诊断特点。在过去的十几年里,已研制了多种针对这种特征的单克隆抗体,主要包括... 哮喘是当今世界上常见的慢性非传染性疾病之一,其特征是可变的气体阻塞,引起呼吸困难和喘息。嗜酸性粒细胞性气道炎症通常被视为慢性气道病变最具影响力的可诊断特点。在过去的十几年里,已研制了多种针对这种特征的单克隆抗体,主要包括抗白细胞介素5(IL-5)或IL-5受体α(美泊利珠单抗、瑞利珠单抗和贝那利珠单抗)、IL-13(来瑞组单抗和曲罗芦单抗)、IL-4受体α(度普利尤单抗)、免疫球蛋白E(奥马珠单抗)和抗胸腺基质淋巴生成素(特泽鲁单抗)的单克隆抗体。本文从哮喘的发病机制、新型抗嗜酸性粒细胞药物在哮喘治疗中的进展等方面进行综述。 展开更多
关键词 哮喘 抗嗜酸性粒细胞药物 嗜酸性粒细胞性气道炎症
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布地奈德联合孟鲁司特对支气管哮喘急性发作患儿的影响
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作者 吴文彬 洪婉倩 《中外医学研究》 2024年第20期151-154,共4页
目的:观察布地奈德联合孟鲁司特对支气管哮喘急性发作患儿的影响。方法:回顾性选取2021年1月—2022年12月泉州市妇幼保健院·儿童医院收治的98例支气管哮喘急性发作患儿的病历资料。根据不同治疗方法将其分为观察组和对照组,各49例... 目的:观察布地奈德联合孟鲁司特对支气管哮喘急性发作患儿的影响。方法:回顾性选取2021年1月—2022年12月泉州市妇幼保健院·儿童医院收治的98例支气管哮喘急性发作患儿的病历资料。根据不同治疗方法将其分为观察组和对照组,各49例。对照组采用布地奈德治疗,观察组在对照组基础上给予孟鲁司特钠治疗。比较两组治疗2周后临床疗效,治疗前后免疫功能、炎症因子及药物安全性。结果:观察组总有效率明显高于对照组,差异有统计学意义(P<0.05)。治疗后,两组免疫球蛋白A(IgA)、免疫球蛋白M(IgM)水平升高,补体C3水平下降,观察组IgA、IgM水平均高于对照组,补体C3水平低于对照组,差异有统计学意义(P<0.05)。治疗后,两组白细胞(WBC)计数、C反应蛋白(CRP)均降低,观察组WBC计数、CRP均低于对照组,差异有统计学意义(P<0.05)。观察组皮疹与声音沙哑发生例数略多于对照组,但两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:布地奈德联合孟鲁司特治疗较单一的布地奈德治疗方法效果更佳,免疫功能恢复更好,并有效调节血清细胞因子水平。 展开更多
关键词 布地奈德 孟鲁司特 支气管哮喘 免疫功能 细胞因子 药物安全
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The role of histamine H4 receptors as a potential targets in allergic rhinitis and asthma 被引量:1
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作者 Eva Hanuskova Jana Plevkova 《Open Journal of Molecular and Integrative Physiology》 2013年第1期6-14,共9页
Histamine—the main product of mast cells plays critical role in the pathogenetic pathways of both allergic rhinitis and asthma. The novel concept of the unique airway diseases its only supported by the similarities w... Histamine—the main product of mast cells plays critical role in the pathogenetic pathways of both allergic rhinitis and asthma. The novel concept of the unique airway diseases its only supported by the similarities within pathogenetic process. Antagonists of H1 and H2 receptors are quite effective in allergic rhinitis, but not effective enough in asthma. In an era of corticosteroids, leucotriene antagonists and Anti-IgE treatment, there is still a challenge to search for more effective, more acurate and more safe treatment option. Antagonists (inversive agonists) of histamine receptors H4 seems to be one of the promising targets in the allergic rhinitis and asthma treatment. The first H4 antagonist entered to clinics and the results from a proof-of-concept Phase II clinical study is expected to be disclosed soon. This review article summarizes current knowledge on H4R that have been collected in various studies sharing evidences about efficacy of H4R as a reasonable target for diseases with histamine involved pathogenetic pathways. 展开更多
关键词 ALLERGIC Rhinits asthma HISTAMINE H4R Novel drug Target
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A Brief Introduction to Researches on Treatment of Hormone-dependent Asthma with Traditional Chinese Medicine
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作者 崔红生 武维屏 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第2期153-159,共7页
In recent years, with the establishment of the theory of air passage inflammation concerning the pathologic mechanism of asthma, the glucocorticoid hormone (referred to hereafter only as hormone for short), a strong i... In recent years, with the establishment of the theory of air passage inflammation concerning the pathologic mechanism of asthma, the glucocorticoid hormone (referred to hereafter only as hormone for short), a strong inflammation killer, has become a fundamental medication for treatment of asthma. However, long period of hormone administration will result in general side effects in the whole body as well as hormone dependence, which has now become a hard problem for physicians. Now a non-hormone medication of immunosuppressant has been chosen in western medicine to treat asthma as a replacement or partial replacement of hormone. Nevertheless, its therapeutic effect is not reliable and its side effects severe, hence hardly acceptable to patients. Traditional Chinese medicine (TCM) always adheres to the principle of holistic treatment and has a great advantage in the treatment of this disease. TCM doctors have made some trials and researches in this area and obtained some accomplishments. The following is a brief account of general researches on the treatment of asthma with TCM. 展开更多
关键词 asthma drugs Chinese Herbal GLUCOCORTICOIDS Humans Substance-Related Disorders
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TCM Treatment of Bronchial Asthma
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作者 张金磊 毛树章 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第2期101-103,共3页
Xuan Fei Ding Chuan Wan ([symbol: see text] pills for facilitating the flow of the lung-qi to relieve asthma) and Xiao Chuan Gu Ben Wan ([symbol: see text] pills for treating asthma by consolidating the origin) were u... Xuan Fei Ding Chuan Wan ([symbol: see text] pills for facilitating the flow of the lung-qi to relieve asthma) and Xiao Chuan Gu Ben Wan ([symbol: see text] pills for treating asthma by consolidating the origin) were used for treatment of bronchial asthma. The cure rate in the treated group (n = 600) was 81.33%, significantly higher (P 展开更多
关键词 ADOLESCENT ADULT Aged asthma drugs Chinese Herbal FEMALE Humans Male Middle Aged
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Shen's Experience in Application of the Drugs for Tonifying the Kidney to.Reduce and Withdraw Adrenocortical Hormone
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作者 王兴娟 刘煜 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第3期181-186,共6页
Adrenocortical hormone (ACH) has antiinflammatory and antiallergic actions, changes stress state and controls the attack of some severe and obstinate diseases. The treatment of chronic diseases with ACH often leads to... Adrenocortical hormone (ACH) has antiinflammatory and antiallergic actions, changes stress state and controls the attack of some severe and obstinate diseases. The treatment of chronic diseases with ACH often leads to its dependence; especially oral administration of ACH for a long time is liable to inhibit the function of hypothalamus-pituitary-adrenocortical-thymic axis (HPAT), and results in the hypo-reservation of adrenal cortex. Hence, sudden ACH withdrawal or decrease often causes the disease recurrence, even adrenocortical crisis. Academician Shen Ziyin has a wealth of clinical experience in both the withdrawal and reduction of ACH and the keeping of therapeutical effectiveness to form his unique remedy in the application of drugs. Shen's rich experience is described as follows. 展开更多
关键词 Adolescent Adult Anti-Inflammatory Agents asthma drugs Chinese Herbal Female Humans Male Middle Aged Nephrosis Lipoid PREDNISONE Substance Withdrawal Syndrome Thyroiditis Subacute
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TRADITIONAL CHINESE MEDICINE IN TREATMENT OF BRONCHITIS AND BRONCHIAL ASTHMA
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作者 陈安民 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1998年第1期71-76,共6页
According to the onset, acute or chronic, and the disease course, long or short, bronchitis can be divided into acute and chronic bronchitis, with their common main symptoms of cough, expectoration and oppression in t... According to the onset, acute or chronic, and the disease course, long or short, bronchitis can be divided into acute and chronic bronchitis, with their common main symptoms of cough, expectoration and oppression in the chest, and basically they belong to the category of 'cough' in traditional Chinese medicine (TCM). 展开更多
关键词 asthma BRONCHITIS Diagnosis Differential drugs Chinese Herbal Humans Medicine Chinese Traditional
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王忆勤巧用虫类药治疗哮病临床经验探析 被引量:1
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作者 赵倩倩 徐璡 +3 位作者 郝一鸣 刘国萍 王忆勤 燕海霞 《上海中医药杂志》 CSCD 2023年第12期46-49,共4页
介绍王忆勤教授巧用虫类药治疗哮病的临床经验。王教授巧用虫类药治疗哮病,屡见佳效,尤善用地龙、全蝎、蜂房等药祛风宣肺、行气化痰平喘、活血祛瘀。并附验案2则。
关键词 哮病 虫类药 病因病机 名医经验 中医药疗法
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孟鲁司特钠联合硫酸镁注射液治疗对支气管哮喘患儿肺功能、免疫功能的影响 被引量:11
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作者 吴萍 李璐 +1 位作者 刘锋娟 胡自然 《临床误诊误治》 CAS 2023年第1期101-104,115,共5页
目的探讨孟鲁司特钠联合硫酸镁注射液治疗对支气管哮喘患儿肺功能、免疫功能的影响及安全性。方法选取2020年2月—2022年5月就诊的支气管哮喘患儿115例,按照不同治疗方式分为观察组63例(给予孟鲁司特钠口服联合硫酸镁注射液静脉泵入)和... 目的探讨孟鲁司特钠联合硫酸镁注射液治疗对支气管哮喘患儿肺功能、免疫功能的影响及安全性。方法选取2020年2月—2022年5月就诊的支气管哮喘患儿115例,按照不同治疗方式分为观察组63例(给予孟鲁司特钠口服联合硫酸镁注射液静脉泵入)和对照组52例(仅给予硫酸镁注射液静脉泵入),比较2组临床疗效、治疗后一般指标,以及治疗前后肺功能、免疫功能指标变化和不良反应发生情况。结果治疗后观察组总有效率高于对照组(P<0.01)。2组治疗后72 h内吸痰次数少于对照组,脉搏氧饱和度恢复时间、痉挛性咳嗽好转时间、肺啰音消散时间及白细胞计数降低时间均短于对照组(P<0.01)。治疗后,2组第1秒用力呼气容积(FEV1)占预计值百分比、用力肺活量(FVC)、FEV1/FVC、CD4+、CD4+/CD8+、免疫球蛋白G、免疫球蛋白A、免疫球蛋白M均有上升,其中观察组上升效果更为显著(P<0.05,P<0.01)。2组不良反应发生率比较差异无统计学意义(P>0.05)。结论孟鲁司特钠联合硫酸镁注射液治疗支气管哮喘患儿效果较好,能有效改善患儿免疫功能和肺功能,且具有较高的安全性。 展开更多
关键词 支气管哮喘 儿童 孟鲁司特钠 硫酸镁注射液 用力肺活量 CD4+ 免疫球蛋白 药物毒性
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