The asymmetric borane reduction of carbonyl compounds using chiral catalysts is one of the most active research. Among them,Oxazaborolidines developed by Corey are most significant- Herein. we report the use of sufony...The asymmetric borane reduction of carbonyl compounds using chiral catalysts is one of the most active research. Among them,Oxazaborolidines developed by Corey are most significant- Herein. we report the use of sufonylamides as chiral catalysts to reduce aromatic ketone in high yield and with e.e. of up to 91 %. Scheme:展开更多
A chiral catalyst, Cp＊RhTsDPEN （Cp＊ = pentamethyl cyclopentadiene, TsDPEN = substitutive phenylsulfonyl-l,2-diphenylethylenediamine）, was synthesized and immobilized at the surface of glass. The immobilized cataly...A chiral catalyst, Cp＊RhTsDPEN （Cp＊ = pentamethyl cyclopentadiene, TsDPEN = substitutive phenylsulfonyl-l,2-diphenylethylenediamine）, was synthesized and immobilized at the surface of glass. The immobilized catalyst exhibited good catalytic efficiency for asymmetric transfer hydrogenation of aromatic ketones in water with HCOONa as hydrogen source.展开更多
文摘The asymmetric borane reduction of carbonyl compounds using chiral catalysts is one of the most active research. Among them,Oxazaborolidines developed by Corey are most significant- Herein. we report the use of sufonylamides as chiral catalysts to reduce aromatic ketone in high yield and with e.e. of up to 91 %. Scheme:
基金the Shanghai Sciences and Technologies Development Fund(Nos.13ZR1458700 and 12nm0500500)the Shanghai Municipal Education Commission(Nos.14YZ074,12ZZ135)Shanghai Normal University(Nos.DXL122,SK201329)for financial support
文摘A chiral catalyst, Cp＊RhTsDPEN （Cp＊ = pentamethyl cyclopentadiene, TsDPEN = substitutive phenylsulfonyl-l,2-diphenylethylenediamine）, was synthesized and immobilized at the surface of glass. The immobilized catalyst exhibited good catalytic efficiency for asymmetric transfer hydrogenation of aromatic ketones in water with HCOONa as hydrogen source.
