目的探讨人绒毛膜促性腺激素(human chorionic gonadotrophin,hCG)激发试验在诊断不同分型性发育异常(disorder of sexual development,DSD)患儿中的价值。方法回顾性分析132例DSD患儿,按染色体核型分为46,XX组(n=10)、46,XY组(n=87)、...目的探讨人绒毛膜促性腺激素(human chorionic gonadotrophin,hCG)激发试验在诊断不同分型性发育异常(disorder of sexual development,DSD)患儿中的价值。方法回顾性分析132例DSD患儿,按染色体核型分为46,XX组(n=10)、46,XY组(n=87)、性染色体异常组(n=35),比较各组患儿hCG激发试验前后的性激素水平,分析形态学上是否存在睾丸组织对hCG激发试验结果的影响。结果3组患儿激发试验后睾酮(testosterone,T)增加倍数比较差异无统计学意义(P>0.05)。46,XY组中,5α-还原酶2缺乏症患儿激发试验后的T与双氢睾酮(dihydrotestosterone,DHT)比值高于其他46,XY DSD患儿(P<0.05)。形态学上,有睾丸组织的DSD患儿激发试验后T增加倍数高于无睾丸组织患儿(P<0.05)。结论hCG激发试验对于评估不同类型的DSD患儿的睾丸间质细胞存在和功能均具有重要价值,对于性腺性质不明确的DSD患儿,均建议行hCG激发试验。展开更多
目的探讨在产后I度子宫脱垂患者中实施低频低刺激联合凯格尔训练的应用效果。方法选取2021年8月—2023年8月富川县人民医院妇产科收治的产后I度子宫脱垂患者72例作为研究对象,采用随机数字表法分为A组与B组,每组36例。其中,A组给予凯格...目的探讨在产后I度子宫脱垂患者中实施低频低刺激联合凯格尔训练的应用效果。方法选取2021年8月—2023年8月富川县人民医院妇产科收治的产后I度子宫脱垂患者72例作为研究对象,采用随机数字表法分为A组与B组,每组36例。其中,A组给予凯格尔训练干预,B组在A组基础上联合使用低频电刺激干预,比较两组临床疗效、盆底功能[采用盆底功能障碍问卷(pelvic floor distress inventory-short form 20,PFDI-20)评估]、心理状态[采用抑郁自评量表(self-rating depression scale,SDS)、焦虑自评量表(self-rating anxiety scale,SAS)评估]、性生活质量[采用女性性功能指数评价表(Female Sexual Function Index,FSFI)评估]。结果干预后,B组临床总有效率较A组偏高(P<0.05)。干预后,两组PFDI-20评分均低于干预前,且B组PFDI-20评分低于A组(P<0.05)。干预后,两组SAS评分、SDS评分均低于干预前,且B组各评分均低于A组(P<0.05)。干预后,两组FSFI评分均高于干预前,且B组FSFI评分高于A组(P<0.05)。结论低频电刺激联合凯格尔训练可提高产后I度子宫脱垂患者临床疗效,增强盆底功能,改善患者心理状态及性生活质量,值得借鉴。展开更多
Although the combination of alcohol and sex is frequently observed in human social interaction, many questions concerning alcohol’s effects on the processing of sexual stimuli and brain functionality remain unanswere...Although the combination of alcohol and sex is frequently observed in human social interaction, many questions concerning alcohol’s effects on the processing of sexual stimuli and brain functionality remain unanswered. Erotic films eliciting sexual arousal in humans and affect electroencephalographic (EEG) activity. This study examines the effects of alcohol on cortical EEG activity in young men while viewing an erotic film. Heterosexual males participated in an independent alcohol/placebo group protocol. Thirty-five minutes after beverage ingestion, EEGs were recorded at prefrontal, temporal and parietal derivations in three conditions: baseline, and while watching erotic and neutral films. During the observation of erotic films, only the participants who drank the placebo beverage showed a decrease in alpha1 and an increase in the fast frequencies of the prefrontal regions, as well as a decrease in inter-prefrontal synchronization in the alpha and beta bands. Alcohol suppressed the prefrontal EEG changes associated with watching erotic visual stimuli without affect the sexual arousal. EEG data show that alcohol affecting the functioning of the prefrontal cortex, which could interfere with the adequate processing of visual erotic stimuli. These findings may contribute to improving our understanding of the brain mechanisms that underlie alcohol’s effects on the processing of sexual stimuli.展开更多
目的:分析盆底磁刺激联合点阵CO_(2)激光治疗阴道松弛症(Vaginal laxity,VL)的疗效。方法:选取2020年12月-2021年8月于笔者科室就诊的VL患者118例,按随机数字表法分为磁刺激组(36例)、激光组(42例)和联合组(40例)。磁刺激组给予盆底磁...目的:分析盆底磁刺激联合点阵CO_(2)激光治疗阴道松弛症(Vaginal laxity,VL)的疗效。方法:选取2020年12月-2021年8月于笔者科室就诊的VL患者118例,按随机数字表法分为磁刺激组(36例)、激光组(42例)和联合组(40例)。磁刺激组给予盆底磁刺激治疗,激光组给予阴道内点阵CO_(2)激光治疗,联合组给予盆底磁刺激治疗+阴道内点阵CO_(2)激光治疗。观察三组患者治疗前及治疗后3个月的阴道健康指数调查表(Vaginal health index score,VHIS)、女性性功能量表(Female sexual function index,FSFI)评分、阴道松弛度及盆底Ⅰ、Ⅱ类肌纤维肌力的变化情况。结果:治疗后3个月,激光组、联合组的VHIS、FSFI评分及阴道松弛程度改善情况均优于同组治疗前,并优于治疗后的磁刺激组(P<0.05);磁刺激组、联合组的盆底Ⅰ、Ⅱ类肌纤维肌力改善情况均优于治疗前,并优于治疗后的激光组(P<0.05)。结论:与单一治疗相比,盆底磁刺激联合点阵CO_(2)激光治疗阴道松弛症疗效更好,值得临床推广应用。展开更多
文摘目的探讨人绒毛膜促性腺激素(human chorionic gonadotrophin,hCG)激发试验在诊断不同分型性发育异常(disorder of sexual development,DSD)患儿中的价值。方法回顾性分析132例DSD患儿,按染色体核型分为46,XX组(n=10)、46,XY组(n=87)、性染色体异常组(n=35),比较各组患儿hCG激发试验前后的性激素水平,分析形态学上是否存在睾丸组织对hCG激发试验结果的影响。结果3组患儿激发试验后睾酮(testosterone,T)增加倍数比较差异无统计学意义(P>0.05)。46,XY组中,5α-还原酶2缺乏症患儿激发试验后的T与双氢睾酮(dihydrotestosterone,DHT)比值高于其他46,XY DSD患儿(P<0.05)。形态学上,有睾丸组织的DSD患儿激发试验后T增加倍数高于无睾丸组织患儿(P<0.05)。结论hCG激发试验对于评估不同类型的DSD患儿的睾丸间质细胞存在和功能均具有重要价值,对于性腺性质不明确的DSD患儿,均建议行hCG激发试验。
文摘目的探讨在产后I度子宫脱垂患者中实施低频低刺激联合凯格尔训练的应用效果。方法选取2021年8月—2023年8月富川县人民医院妇产科收治的产后I度子宫脱垂患者72例作为研究对象,采用随机数字表法分为A组与B组,每组36例。其中,A组给予凯格尔训练干预,B组在A组基础上联合使用低频电刺激干预,比较两组临床疗效、盆底功能[采用盆底功能障碍问卷(pelvic floor distress inventory-short form 20,PFDI-20)评估]、心理状态[采用抑郁自评量表(self-rating depression scale,SDS)、焦虑自评量表(self-rating anxiety scale,SAS)评估]、性生活质量[采用女性性功能指数评价表(Female Sexual Function Index,FSFI)评估]。结果干预后,B组临床总有效率较A组偏高(P<0.05)。干预后,两组PFDI-20评分均低于干预前,且B组PFDI-20评分低于A组(P<0.05)。干预后,两组SAS评分、SDS评分均低于干预前,且B组各评分均低于A组(P<0.05)。干预后,两组FSFI评分均高于干预前,且B组FSFI评分高于A组(P<0.05)。结论低频电刺激联合凯格尔训练可提高产后I度子宫脱垂患者临床疗效,增强盆底功能,改善患者心理状态及性生活质量,值得借鉴。
文摘Although the combination of alcohol and sex is frequently observed in human social interaction, many questions concerning alcohol’s effects on the processing of sexual stimuli and brain functionality remain unanswered. Erotic films eliciting sexual arousal in humans and affect electroencephalographic (EEG) activity. This study examines the effects of alcohol on cortical EEG activity in young men while viewing an erotic film. Heterosexual males participated in an independent alcohol/placebo group protocol. Thirty-five minutes after beverage ingestion, EEGs were recorded at prefrontal, temporal and parietal derivations in three conditions: baseline, and while watching erotic and neutral films. During the observation of erotic films, only the participants who drank the placebo beverage showed a decrease in alpha1 and an increase in the fast frequencies of the prefrontal regions, as well as a decrease in inter-prefrontal synchronization in the alpha and beta bands. Alcohol suppressed the prefrontal EEG changes associated with watching erotic visual stimuli without affect the sexual arousal. EEG data show that alcohol affecting the functioning of the prefrontal cortex, which could interfere with the adequate processing of visual erotic stimuli. These findings may contribute to improving our understanding of the brain mechanisms that underlie alcohol’s effects on the processing of sexual stimuli.
文摘目的:分析盆底磁刺激联合点阵CO_(2)激光治疗阴道松弛症(Vaginal laxity,VL)的疗效。方法:选取2020年12月-2021年8月于笔者科室就诊的VL患者118例,按随机数字表法分为磁刺激组(36例)、激光组(42例)和联合组(40例)。磁刺激组给予盆底磁刺激治疗,激光组给予阴道内点阵CO_(2)激光治疗,联合组给予盆底磁刺激治疗+阴道内点阵CO_(2)激光治疗。观察三组患者治疗前及治疗后3个月的阴道健康指数调查表(Vaginal health index score,VHIS)、女性性功能量表(Female sexual function index,FSFI)评分、阴道松弛度及盆底Ⅰ、Ⅱ类肌纤维肌力的变化情况。结果:治疗后3个月,激光组、联合组的VHIS、FSFI评分及阴道松弛程度改善情况均优于同组治疗前,并优于治疗后的磁刺激组(P<0.05);磁刺激组、联合组的盆底Ⅰ、Ⅱ类肌纤维肌力改善情况均优于治疗前,并优于治疗后的激光组(P<0.05)。结论:与单一治疗相比,盆底磁刺激联合点阵CO_(2)激光治疗阴道松弛症疗效更好,值得临床推广应用。
