Maintainability is an important design characterist ic , and also is a design parameter. The essence of maintainability design is to ex pect and solve possible maintenance problems at early stage during product devel ...Maintainability is an important design characterist ic , and also is a design parameter. The essence of maintainability design is to ex pect and solve possible maintenance problems at early stage during product devel opment, maintainability must be designed into product simultaneously. But curren t maintainability methods do not support concurrent engineering. This paper anal yzes the deficiencies of existing maintainability technologies, and introduces t he concept of maintainability analysis visualization. The two major deficiencies are that maintainability analysis time lags behind product design, and the main tainability techniques do not accommodate modern product design concepts. After this, the infrastructure of maintainability analysis visualization system is dis cussed. The system are composed of four subsystems, they are product modeling, d isassembly process modeling, simulation and analysis, and user interface. Produc t modeling is accomplished with the capability of CAD system, disassembly proces s modeling is mainly a reason process based on assembly information. The system is integrated into AutoCAD so that designer can timely analyze their product des ign from the viewpoint of easy maintenance. Human model generation function, hum an task analysis function, tool analysis function, visibility analysis function is implemented, disassembly process planning function is still under developing.展开更多
目的系统评价香砂六君子汤联合化疗治疗中晚期胃癌的安全性和疗效性,并通过GRADE质量评价分析证据等级。方法检索中国知网、万方数据知识服务平台、维普中文科技期刊数据库(中文科技期刊数据库)、PubMed、Cochrane Library、Web of Scie...目的系统评价香砂六君子汤联合化疗治疗中晚期胃癌的安全性和疗效性,并通过GRADE质量评价分析证据等级。方法检索中国知网、万方数据知识服务平台、维普中文科技期刊数据库(中文科技期刊数据库)、PubMed、Cochrane Library、Web of Science数据库建库至2023年7月发表的文章,利用EndNote X9、Review Manager 5.3软件进行文献筛选与剔除、meta分析。结果共纳入18篇文献,研究例数共1430例,其中研究组717例,对照组713例。meta分析结果显示,香砂六君子汤联合化疗可以提高肿瘤治疗有效率(OR=2.17,95%CI:1.65~2.85,P<0.00001)、中医症候评分(OR=4.89,95%CI:2.40~9.98,P<0.0001)及生活质量(MD=6.40,95%CI:4.19~8.60,P<0.00001),减少恶性呕吐(OR=0.14,95%CI:0.08~0.24,P<0.0001)和白细胞减少的发生数(OR=0.35,95%CI:0.17~0.72,P=0.005),主要是减少Ⅲ~Ⅳ级的白细胞减少发生数(OR=0.22,95%CI:0.12~0.38,P<0.00001),但对腹泻(OR=0.31,95%CI:0.09~0.32,P<0.00001)的meta分析有统计学意义,但无显著性差异。结论香砂六君子汤联合化疗可以提高晚期胃癌治疗的效果,减少不良反应的发生,给临床治疗胃癌提供了理论依据。展开更多
文摘Maintainability is an important design characterist ic , and also is a design parameter. The essence of maintainability design is to ex pect and solve possible maintenance problems at early stage during product devel opment, maintainability must be designed into product simultaneously. But curren t maintainability methods do not support concurrent engineering. This paper anal yzes the deficiencies of existing maintainability technologies, and introduces t he concept of maintainability analysis visualization. The two major deficiencies are that maintainability analysis time lags behind product design, and the main tainability techniques do not accommodate modern product design concepts. After this, the infrastructure of maintainability analysis visualization system is dis cussed. The system are composed of four subsystems, they are product modeling, d isassembly process modeling, simulation and analysis, and user interface. Produc t modeling is accomplished with the capability of CAD system, disassembly proces s modeling is mainly a reason process based on assembly information. The system is integrated into AutoCAD so that designer can timely analyze their product des ign from the viewpoint of easy maintenance. Human model generation function, hum an task analysis function, tool analysis function, visibility analysis function is implemented, disassembly process planning function is still under developing.
