It is well established that guidance of axons during neuronal development is regulated by a variety of extracellular signals,governing cytoskeletal dynamics in growth cones.The actin and microtubule(MT)cytoskeleton ...It is well established that guidance of axons during neuronal development is regulated by a variety of extracellular signals,governing cytoskeletal dynamics in growth cones.The actin and microtubule(MT)cytoskeleton have both been shown to play important roles.However,a growing body of work suggests that a critical issue is the proper coordination of changes within these two major cytoskeletal systems(reviewed in Cammara-ta et al., 2016).展开更多
基金supported by the Hungarian Science Foundation(OTKA)(K109330 to JM)the Hungarian Brain Research Program(KTIA_NAP_13-2-2014-0007 to JM)+1 种基金the National Research,Development and Innovation Office(GINOP-2.3.2-15-2016-00001 and GINOP-2.3.2-15-2016-00032 to JM)by an MTA Postdoctoral Fellowship(to IF)
文摘It is well established that guidance of axons during neuronal development is regulated by a variety of extracellular signals,governing cytoskeletal dynamics in growth cones.The actin and microtubule(MT)cytoskeleton have both been shown to play important roles.However,a growing body of work suggests that a critical issue is the proper coordination of changes within these two major cytoskeletal systems(reviewed in Cammara-ta et al., 2016).