Helicobacter pylori(H.pylori)infection has a protective effect on gastroesophageal reflux disease(GERD).Both of these diseases have a very high incidence and prevalence.As a result,GERD often recurs after anti-Helicob...Helicobacter pylori(H.pylori)infection has a protective effect on gastroesophageal reflux disease(GERD).Both of these diseases have a very high incidence and prevalence.As a result,GERD often recurs after anti-Helicobacter therapy.The problem of effective treatment of H.pylori infection and GERD is that the main groups of drugs[proton pump inhibitors(PPIs)and potassium-competitive acid blockers]have the possibility of side effects with use.Such supposed side effects have no evidence in randomized controlled trials that comply with the principles of evidence-based medicine.Morphological changes in the gastric mucosa after long-term use of antisecretory drugs should be considered as compensatory mechanisms of sanogenesis.The greatest concern for doctors who treat patients with antisecretory drugs is the risk of gastric carcinogenesis.This article presents an analysis of morphological and pathophysiological changes that occur after long-term use of antisecretory drugs(PPIs).Hypertrophy(hyperplasia)of G cells,enterochromaffin-like cells and possible fundic gland polyps(hyperplasia)are compensatory mechanisms of sanogenesis during long-term treatment with PPIs.These mechanisms are of primary importance for rehabilitation and prevention of complications in patients with GERD,non-steroidal anti-inflammatory drugsgastropathy and other diseases during long-term treatment with PPIs.Understanding the pathophysiological and morphological mechanisms of compensation and adaptation,the mechanisms of sanogenesis and carcinogenesis will increase the number of indications for long-term use of PPIs with a high level of efficiency and safety of treatment.In addition,understanding the pathophysiological and morphological mechanisms of compensation and adaptation,the mechanisms of sanogenesis will allow us to forecast the side effects of long-term use of potassium-competitive acid blockers.展开更多
A Mobile Ad Hoc Network (MANET) is a collection of mobile nodes that can communicate directly over wireless media, without the need for a preconfigured infrastructure. Several approaches have been suggested to improve...A Mobile Ad Hoc Network (MANET) is a collection of mobile nodes that can communicate directly over wireless media, without the need for a preconfigured infrastructure. Several approaches have been suggested to improve Quality of Service (QoS) in IEEE 802.11-based MANETs through modifying some of the IEEE 802.11 Medium Access Control (MAC) algorithms, such as the backoff algorithm that is used to control the packets collision aftermath. In this work, an adaptive IEEE 802.11 backoff algorithm to improve QoS is de-veloped and tested in simulations as well as in testbed implementation. While the Binary Exponential Backoff (BEB) algorithm deployed by IEEE 802.11 reacts based on individual packet transmit trials, the new algo-rithm takes the history of successive packet transmit trials into account to provide a better QoS performance. The new algorithm has been tested against the legacy IEEE 802.11 through simulations using QualNet and a Linux-based testbed comprising a number of stations. The performed tests have shown significant im-provements in performance, with up to 33.51% improvement in delay and 7.36% improvement in packet delivery fraction compared to the original IEEE 802.11.展开更多
Grant-free random access(RA)is attractive for future network due to the minimized access delay.In this paper,we investigate the grantfree RA in multicell massive multiple-input multipleoutput(MIMO)systems with pilot r...Grant-free random access(RA)is attractive for future network due to the minimized access delay.In this paper,we investigate the grantfree RA in multicell massive multiple-input multipleoutput(MIMO)systems with pilot reuse.With backoff mechanism,user equipments(UEs)in each cell are randomly activated,and active UEs randomly select orthogonal pilots from a predefined pilot pool,which results in a random pilot contamination among cells.With the help of indicators that capture the uncertainties of UE activation and pilot selection,we derive a closed-form approximation of the spectral efficiency per cell after averaging over the channel fading as well as UEs’random behaviors.Based on the analysis,the optimal backoff parameter and pilot length that maximize the spectral efficiency can be obtained.We find that the backoff mechanism is necessary for the system with large number of UEs,as it can bring significant gains on the spectral efficiency.Moreover,as UE number grows,more backoff time is needed.展开更多
Mobile Ad hoc Network (MANET) is a wireless network consisting of mobile devices (laptops, smart phones, etc.) that move and communicate with each other without the use of any existing network infrastructure or centra...Mobile Ad hoc Network (MANET) is a wireless network consisting of mobile devices (laptops, smart phones, etc.) that move and communicate with each other without the use of any existing network infrastructure or centralized server to avoid collisions which have negative effects on the performance of the network. Access to the shared media is controlled by a Backoff algorithm that is a part of the Media Access Protocol. In this paper, we improve the History Based Probabilistic Backoff (HPPB) algorithm by modifying the increment/decrement behavior of the Contention Window to introduce History Based Increment Backoff (HBIB) algorithm which outperforms HBPB in terms of throughput and end-to-end delay with various numbers of nodes and different traffic loads.展开更多
Based on the Distributed Coordination Function (DCF) and the Enhanced DCF (EDCF) mechanisms in IEEE 802.11 and 802.11e, a novel backoff scheme for Wireless Local Area Network (WLAN) is proposed. The scheme is to solve...Based on the Distributed Coordination Function (DCF) and the Enhanced DCF (EDCF) mechanisms in IEEE 802.11 and 802.11e, a novel backoff scheme for Wireless Local Area Network (WLAN) is proposed. The scheme is to solve the problem of the packet loss and the decrease of performance due to the increasing Contention Window (CW) when there are continuous collisions. In the proposed scheme, the CW of the packet will change dynamically with different delay for the different traffics. Mathematic formulas are presented to indicate the relationship between the CW and the delay character. ,The performance of the new scheme is also discussed with simulation results. The results show that it helps WLAN system handle multimedia simultaneously.展开更多
A novel backoff algorithm in CSMA/CA-based medium access control (MAC) protocols for clustered sensor networks was proposed. The algorithm requires that all sensor nodes have the same value of contention window (CW) i...A novel backoff algorithm in CSMA/CA-based medium access control (MAC) protocols for clustered sensor networks was proposed. The algorithm requires that all sensor nodes have the same value of contention window (CW) in a cluster, which is revealed by formulating resource allocation as a network utility maximization problem. Then, by maximizing the total network utility with constrains of minimizing collision probability, the optimal value of CW (Wopt) can be computed according to the number of sensor nodes. The new backoff algorithm uses the common optimal value Wopt and leads to fewer collisions than binary exponential backoff algorithm. The simulation results show that the proposed algorithm outperforms standard 802.11 DCF and S-MAC in average collision times, packet delay, total energy consumption, and system throughput.展开更多
The increased adoption of Internet of Medical Things (IoMT) technologies has resulted in the widespread use ofBody Area Networks (BANs) in medical and non-medical domains. However, the performance of IEEE 802.15.4-bas...The increased adoption of Internet of Medical Things (IoMT) technologies has resulted in the widespread use ofBody Area Networks (BANs) in medical and non-medical domains. However, the performance of IEEE 802.15.4-based BANs is impacted by challenges related to heterogeneous data traffic requirements among nodes, includingcontention during finite backoff periods, association delays, and traffic channel access through clear channelassessment (CCA) algorithms. These challenges lead to increased packet collisions, queuing delays, retransmissions,and the neglect of critical traffic, thereby hindering performance indicators such as throughput, packet deliveryratio, packet drop rate, and packet delay. Therefore, we propose Dynamic Next Backoff Period and Clear ChannelAssessment (DNBP-CCA) schemes to address these issues. The DNBP-CCA schemes leverage a combination ofthe Dynamic Next Backoff Period (DNBP) scheme and the Dynamic Next Clear Channel Assessment (DNCCA)scheme. The DNBP scheme employs a fuzzy Takagi, Sugeno, and Kang (TSK) model’s inference system toquantitatively analyze backoff exponent, channel clearance, collision ratio, and data rate as input parameters. Onthe other hand, the DNCCA scheme dynamically adapts the CCA process based on requested data transmission tothe coordinator, considering input parameters such as buffer status ratio and acknowledgement ratio. As a result,simulations demonstrate that our proposed schemes are better than some existing representative approaches andenhance data transmission, reduce node collisions, improve average throughput, and packet delivery ratio, anddecrease average packet drop rate and packet delay.展开更多
Ad hoc网络是一种特殊的对等式网络。传统的基于固定的或有中心的网络的协议不能满足 Ad hoc网络的需要。首先研究了 Ad hoc网络信道接入协议要考虑的隐终端问题和暴露终端问题 ,并给出了一种可能的双信道解决方案。在分析了现有的两种...Ad hoc网络是一种特殊的对等式网络。传统的基于固定的或有中心的网络的协议不能满足 Ad hoc网络的需要。首先研究了 Ad hoc网络信道接入协议要考虑的隐终端问题和暴露终端问题 ,并给出了一种可能的双信道解决方案。在分析了现有的两种退避算法后 ,提出使用退避计数器广播加信道争用估计技术来消除不公平现象。在这些结果的基础上 ,提出了一种新的信道接入协议。展开更多
文摘Helicobacter pylori(H.pylori)infection has a protective effect on gastroesophageal reflux disease(GERD).Both of these diseases have a very high incidence and prevalence.As a result,GERD often recurs after anti-Helicobacter therapy.The problem of effective treatment of H.pylori infection and GERD is that the main groups of drugs[proton pump inhibitors(PPIs)and potassium-competitive acid blockers]have the possibility of side effects with use.Such supposed side effects have no evidence in randomized controlled trials that comply with the principles of evidence-based medicine.Morphological changes in the gastric mucosa after long-term use of antisecretory drugs should be considered as compensatory mechanisms of sanogenesis.The greatest concern for doctors who treat patients with antisecretory drugs is the risk of gastric carcinogenesis.This article presents an analysis of morphological and pathophysiological changes that occur after long-term use of antisecretory drugs(PPIs).Hypertrophy(hyperplasia)of G cells,enterochromaffin-like cells and possible fundic gland polyps(hyperplasia)are compensatory mechanisms of sanogenesis during long-term treatment with PPIs.These mechanisms are of primary importance for rehabilitation and prevention of complications in patients with GERD,non-steroidal anti-inflammatory drugsgastropathy and other diseases during long-term treatment with PPIs.Understanding the pathophysiological and morphological mechanisms of compensation and adaptation,the mechanisms of sanogenesis and carcinogenesis will increase the number of indications for long-term use of PPIs with a high level of efficiency and safety of treatment.In addition,understanding the pathophysiological and morphological mechanisms of compensation and adaptation,the mechanisms of sanogenesis will allow us to forecast the side effects of long-term use of potassium-competitive acid blockers.
文摘A Mobile Ad Hoc Network (MANET) is a collection of mobile nodes that can communicate directly over wireless media, without the need for a preconfigured infrastructure. Several approaches have been suggested to improve Quality of Service (QoS) in IEEE 802.11-based MANETs through modifying some of the IEEE 802.11 Medium Access Control (MAC) algorithms, such as the backoff algorithm that is used to control the packets collision aftermath. In this work, an adaptive IEEE 802.11 backoff algorithm to improve QoS is de-veloped and tested in simulations as well as in testbed implementation. While the Binary Exponential Backoff (BEB) algorithm deployed by IEEE 802.11 reacts based on individual packet transmit trials, the new algo-rithm takes the history of successive packet transmit trials into account to provide a better QoS performance. The new algorithm has been tested against the legacy IEEE 802.11 through simulations using QualNet and a Linux-based testbed comprising a number of stations. The performed tests have shown significant im-provements in performance, with up to 33.51% improvement in delay and 7.36% improvement in packet delivery fraction compared to the original IEEE 802.11.
基金supported in part by the National Natural Science Foundation of China under Grant 62171231 and 62071247in part by the National Key Research & Development Program of China under Grant No. 2020YFB1807202 and 2020YFB1804900
文摘Grant-free random access(RA)is attractive for future network due to the minimized access delay.In this paper,we investigate the grantfree RA in multicell massive multiple-input multipleoutput(MIMO)systems with pilot reuse.With backoff mechanism,user equipments(UEs)in each cell are randomly activated,and active UEs randomly select orthogonal pilots from a predefined pilot pool,which results in a random pilot contamination among cells.With the help of indicators that capture the uncertainties of UE activation and pilot selection,we derive a closed-form approximation of the spectral efficiency per cell after averaging over the channel fading as well as UEs’random behaviors.Based on the analysis,the optimal backoff parameter and pilot length that maximize the spectral efficiency can be obtained.We find that the backoff mechanism is necessary for the system with large number of UEs,as it can bring significant gains on the spectral efficiency.Moreover,as UE number grows,more backoff time is needed.
文摘Mobile Ad hoc Network (MANET) is a wireless network consisting of mobile devices (laptops, smart phones, etc.) that move and communicate with each other without the use of any existing network infrastructure or centralized server to avoid collisions which have negative effects on the performance of the network. Access to the shared media is controlled by a Backoff algorithm that is a part of the Media Access Protocol. In this paper, we improve the History Based Probabilistic Backoff (HPPB) algorithm by modifying the increment/decrement behavior of the Contention Window to introduce History Based Increment Backoff (HBIB) algorithm which outperforms HBPB in terms of throughput and end-to-end delay with various numbers of nodes and different traffic loads.
基金Supported by the National Natural Science Foundation of China (No.90304008) ShaanxiInternational Cooperation Project 2003KW-08.
文摘Based on the Distributed Coordination Function (DCF) and the Enhanced DCF (EDCF) mechanisms in IEEE 802.11 and 802.11e, a novel backoff scheme for Wireless Local Area Network (WLAN) is proposed. The scheme is to solve the problem of the packet loss and the decrease of performance due to the increasing Contention Window (CW) when there are continuous collisions. In the proposed scheme, the CW of the packet will change dynamically with different delay for the different traffics. Mathematic formulas are presented to indicate the relationship between the CW and the delay character. ,The performance of the new scheme is also discussed with simulation results. The results show that it helps WLAN system handle multimedia simultaneously.
基金Project(60772088) supported by the National Natural Science Foundation of China
文摘A novel backoff algorithm in CSMA/CA-based medium access control (MAC) protocols for clustered sensor networks was proposed. The algorithm requires that all sensor nodes have the same value of contention window (CW) in a cluster, which is revealed by formulating resource allocation as a network utility maximization problem. Then, by maximizing the total network utility with constrains of minimizing collision probability, the optimal value of CW (Wopt) can be computed according to the number of sensor nodes. The new backoff algorithm uses the common optimal value Wopt and leads to fewer collisions than binary exponential backoff algorithm. The simulation results show that the proposed algorithm outperforms standard 802.11 DCF and S-MAC in average collision times, packet delay, total energy consumption, and system throughput.
基金Research Supporting Project Number(RSP2024R421),King Saud University,Riyadh,Saudi Arabia。
文摘The increased adoption of Internet of Medical Things (IoMT) technologies has resulted in the widespread use ofBody Area Networks (BANs) in medical and non-medical domains. However, the performance of IEEE 802.15.4-based BANs is impacted by challenges related to heterogeneous data traffic requirements among nodes, includingcontention during finite backoff periods, association delays, and traffic channel access through clear channelassessment (CCA) algorithms. These challenges lead to increased packet collisions, queuing delays, retransmissions,and the neglect of critical traffic, thereby hindering performance indicators such as throughput, packet deliveryratio, packet drop rate, and packet delay. Therefore, we propose Dynamic Next Backoff Period and Clear ChannelAssessment (DNBP-CCA) schemes to address these issues. The DNBP-CCA schemes leverage a combination ofthe Dynamic Next Backoff Period (DNBP) scheme and the Dynamic Next Clear Channel Assessment (DNCCA)scheme. The DNBP scheme employs a fuzzy Takagi, Sugeno, and Kang (TSK) model’s inference system toquantitatively analyze backoff exponent, channel clearance, collision ratio, and data rate as input parameters. Onthe other hand, the DNCCA scheme dynamically adapts the CCA process based on requested data transmission tothe coordinator, considering input parameters such as buffer status ratio and acknowledgement ratio. As a result,simulations demonstrate that our proposed schemes are better than some existing representative approaches andenhance data transmission, reduce node collisions, improve average throughput, and packet delivery ratio, anddecrease average packet drop rate and packet delay.
文摘Ad hoc网络是一种特殊的对等式网络。传统的基于固定的或有中心的网络的协议不能满足 Ad hoc网络的需要。首先研究了 Ad hoc网络信道接入协议要考虑的隐终端问题和暴露终端问题 ,并给出了一种可能的双信道解决方案。在分析了现有的两种退避算法后 ,提出使用退避计数器广播加信道争用估计技术来消除不公平现象。在这些结果的基础上 ,提出了一种新的信道接入协议。
