Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have ...Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging population.Posture and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous mechanisms.To effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory signals.The mechanisms which underpin the integration of these multisensory signals are the principal topic of the present work.Existing multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older adults.Insufficient emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and balance.In the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s disease.We also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older adults.Lastly,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases.展开更多
A 4-12GHz wideband power amplifier,using a balanced configuration with a strip line Lange coupler, is designed and fabricated. This power amplifier shows a maximum continuous wave output power of 29.5dBm at 8GHz cente...A 4-12GHz wideband power amplifier,using a balanced configuration with a strip line Lange coupler, is designed and fabricated. This power amplifier shows a maximum continuous wave output power of 29.5dBm at 8GHz center frequency with an associated gain of 8.5dB and a gain flatness of ＋ /- 0.6dB in the 4-12GHz frequency range.展开更多
One of the challenging scheduling problems in Cloud data centers is to take the allocation and migration of reconfigurable virtual machines as well as the integrated features of hosting physical machines into consider...One of the challenging scheduling problems in Cloud data centers is to take the allocation and migration of reconfigurable virtual machines as well as the integrated features of hosting physical machines into consideration. We introduce a Dynamic and Integrated Resource Scheduling algorithm (DAIRS) for Cloud data centers. Unlike traditional load-balance scheduling algorithms which often consider only one factor such as the CPU load in physical servers, DAIRS treats CPU, memory and network bandwidth integrated for both physical machines and virtual machines. We develop integrated measurement for the total imbalance level of a Cloud datacenter as well as the average imbalance level of each server. Simulation results show that DAIRS has good performance with regard to total imbalance level, average imbalance level of each server, as well as overall running time.展开更多
There are two key issues in distributed intrusion detection system,that is,maintaining load balance of system and protecting data integrity.To address these issues,this paper proposes a new distributed intrusion detec...There are two key issues in distributed intrusion detection system,that is,maintaining load balance of system and protecting data integrity.To address these issues,this paper proposes a new distributed intrusion detection model for big data based on nondestructive partitioning and balanced allocation.A data allocation strategy based on capacity and workload is introduced to achieve local load balance,and a dynamic load adjustment strategy is adopted to maintain global load balance of cluster.Moreover,data integrity is protected by using session reassemble and session partitioning.The simulation results show that the new model enjoys favorable advantages such as good load balance,higher detection rate and detection efficiency.展开更多
Accurate and detailed information of hydrological balance, and its dynamic nature is needed to develop strategies for sustainable use and management of water resources. In this concern, a fully integrated MIKE SHE mod...Accurate and detailed information of hydrological balance, and its dynamic nature is needed to develop strategies for sustainable use and management of water resources. In this concern, a fully integrated MIKE SHE model was developed to study the hydrological balance of the Chirchik River Basin, Uzbekistan. Parameters in the model were calibrated and simulated results were validated for the periods 2009-2011 and 2012-2013 in term of two observed hydrological parameters: streamflow rate and groundwater table. After the successful calibration of the parameters, the model produced quantitative results of the water cycle and provided better understanding of the surface and groundwater interactions. The results show that the hydrological balance is strongly dependent on the intensity of agricultural activity within the basin. An actual evapotranspiration was found as a main water loss element among the water transport components due to large-scale agricultural irrigation activities. This corresponds to 77% of the total water budget as an average. A satisfactory water balance simulation error was obtained after adjusting model parameters to basin environment.展开更多
文摘Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging population.Posture and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous mechanisms.To effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory signals.The mechanisms which underpin the integration of these multisensory signals are the principal topic of the present work.Existing multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older adults.Insufficient emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and balance.In the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s disease.We also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older adults.Lastly,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases.
文摘A 4-12GHz wideband power amplifier,using a balanced configuration with a strip line Lange coupler, is designed and fabricated. This power amplifier shows a maximum continuous wave output power of 29.5dBm at 8GHz center frequency with an associated gain of 8.5dB and a gain flatness of ＋ /- 0.6dB in the 4-12GHz frequency range.
基金supported by Scientific Research Foundation for the Returned Overseas Chinese ScholarsState Education Ministry under Grant No.2010-2011 and Chinese Post-doctoral Research Foundation
文摘One of the challenging scheduling problems in Cloud data centers is to take the allocation and migration of reconfigurable virtual machines as well as the integrated features of hosting physical machines into consideration. We introduce a Dynamic and Integrated Resource Scheduling algorithm (DAIRS) for Cloud data centers. Unlike traditional load-balance scheduling algorithms which often consider only one factor such as the CPU load in physical servers, DAIRS treats CPU, memory and network bandwidth integrated for both physical machines and virtual machines. We develop integrated measurement for the total imbalance level of a Cloud datacenter as well as the average imbalance level of each server. Simulation results show that DAIRS has good performance with regard to total imbalance level, average imbalance level of each server, as well as overall running time.
文摘There are two key issues in distributed intrusion detection system,that is,maintaining load balance of system and protecting data integrity.To address these issues,this paper proposes a new distributed intrusion detection model for big data based on nondestructive partitioning and balanced allocation.A data allocation strategy based on capacity and workload is introduced to achieve local load balance,and a dynamic load adjustment strategy is adopted to maintain global load balance of cluster.Moreover,data integrity is protected by using session reassemble and session partitioning.The simulation results show that the new model enjoys favorable advantages such as good load balance,higher detection rate and detection efficiency.
文摘Accurate and detailed information of hydrological balance, and its dynamic nature is needed to develop strategies for sustainable use and management of water resources. In this concern, a fully integrated MIKE SHE model was developed to study the hydrological balance of the Chirchik River Basin, Uzbekistan. Parameters in the model were calibrated and simulated results were validated for the periods 2009-2011 and 2012-2013 in term of two observed hydrological parameters: streamflow rate and groundwater table. After the successful calibration of the parameters, the model produced quantitative results of the water cycle and provided better understanding of the surface and groundwater interactions. The results show that the hydrological balance is strongly dependent on the intensity of agricultural activity within the basin. An actual evapotranspiration was found as a main water loss element among the water transport components due to large-scale agricultural irrigation activities. This corresponds to 77% of the total water budget as an average. A satisfactory water balance simulation error was obtained after adjusting model parameters to basin environment.
