Objective:To determine the association of the three umbilical cord blood parameters:umbilical cord pH,base deficit,and lactate levels,with neonatal outcomes.Methods:This prospective observational study was conducted f...Objective:To determine the association of the three umbilical cord blood parameters:umbilical cord pH,base deficit,and lactate levels,with neonatal outcomes.Methods:This prospective observational study was conducted from April 2021 to September 2022 with 100 term and late preterm(>35 weeks)neonates whose umbilical cord blood pH was<7.10,Apgar score was<7 at 1 min,and required positive pressure ventilation.Umbilical cord blood was assessed for pH,base deficit,and blood lactate levels.The neonatal outcomes of neonatal intensive care unit admission,Apgar score at 1 min,and Apgar score at 5 min were assessed.Results:The mean of umbilical cord blood pH was 7.04±0.07,mean base deficit was(−9.3±3.9)mmol/L,and mean lactate levels were(6.51±2.29)mmol/L.Neonatal intensive care unit(NICU)admission was needed in 78(78%)neonates.The mean NICU stay length was(2.4±2.2)days ranging from 0 to 12 days with a median of 2 days.Univariate analysis showed no significant difference in cord blood pH(P=0.736)and base deficit(P=0.393)between neonates without NICU admission and neonates who required NICU admission,but lactate level was significantly higher in neonates who required NICU admission(P<0.001).There was no significant difference in cord blood pH(P=0.400)and base deficit(P>0.999)between neonates with Apgar scores 4-7 at 1 min and neonates with Apgar scores<4,but lactate level was significantly higher in neonates with Apgar scores<4 at 1 min(P<0.001).Conclusions:Umbilical cord blood pH,base deficit,and lactate levels are useful novel markers showing a significant correlation with neonatal intensive care unit admission and adverse neonatal morbidities among hypoxic newborns.Overall,lactate was a better predictor of adverse neonatal outcomes as compared to umbilical cord blood pH and base deficit.展开更多
Children with attention deficit and hyper activity disorder have various problems such as low academic performance, social and communication problems, anxiety, depression, aggression, conduct disorder and delinquency,...Children with attention deficit and hyper activity disorder have various problems such as low academic performance, social and communication problems, anxiety, depression, aggression, conduct disorder and delinquency, and also when they become adults, they have problems in social relationships that these problems can increase or decrease in dealing with family. Hence, this study was performed in order to examine the impact of family-based behavioral treatment compared with Barkley behavior therapy in reducing symptoms of children with attention deficit disorder—ADHD. To meet the aim, 20 of children with age range of 7 to 12 years old with attention deficit disorder—hyperactivity were selected in both experimental and control groups, and exposed to the treatment of behavioral family therapy groups and changes in behavior Barkley. Before and after the treatment, they were evaluated according to the scale of the Conner’s Parent Rating Scale-Revised Short Form (CPRS-R: S). Results of multivariate analysis of covariance indicated that there were significant differences between the experimental group who had received family-based behavioral treatments based on changes in behavior Barkley and a control group who had received drug treatment in variables, including conduct problems, learning problems, psychosomatic symptoms, and signs of impulsive hyperactivity, anxiety and hyperactivity (p < 0.01). These results could be guidance for counsel or sand therapists for children with attention deficit disorder—ADHD.展开更多
文摘Objective:To determine the association of the three umbilical cord blood parameters:umbilical cord pH,base deficit,and lactate levels,with neonatal outcomes.Methods:This prospective observational study was conducted from April 2021 to September 2022 with 100 term and late preterm(>35 weeks)neonates whose umbilical cord blood pH was<7.10,Apgar score was<7 at 1 min,and required positive pressure ventilation.Umbilical cord blood was assessed for pH,base deficit,and blood lactate levels.The neonatal outcomes of neonatal intensive care unit admission,Apgar score at 1 min,and Apgar score at 5 min were assessed.Results:The mean of umbilical cord blood pH was 7.04±0.07,mean base deficit was(−9.3±3.9)mmol/L,and mean lactate levels were(6.51±2.29)mmol/L.Neonatal intensive care unit(NICU)admission was needed in 78(78%)neonates.The mean NICU stay length was(2.4±2.2)days ranging from 0 to 12 days with a median of 2 days.Univariate analysis showed no significant difference in cord blood pH(P=0.736)and base deficit(P=0.393)between neonates without NICU admission and neonates who required NICU admission,but lactate level was significantly higher in neonates who required NICU admission(P<0.001).There was no significant difference in cord blood pH(P=0.400)and base deficit(P>0.999)between neonates with Apgar scores 4-7 at 1 min and neonates with Apgar scores<4,but lactate level was significantly higher in neonates with Apgar scores<4 at 1 min(P<0.001).Conclusions:Umbilical cord blood pH,base deficit,and lactate levels are useful novel markers showing a significant correlation with neonatal intensive care unit admission and adverse neonatal morbidities among hypoxic newborns.Overall,lactate was a better predictor of adverse neonatal outcomes as compared to umbilical cord blood pH and base deficit.
文摘Children with attention deficit and hyper activity disorder have various problems such as low academic performance, social and communication problems, anxiety, depression, aggression, conduct disorder and delinquency, and also when they become adults, they have problems in social relationships that these problems can increase or decrease in dealing with family. Hence, this study was performed in order to examine the impact of family-based behavioral treatment compared with Barkley behavior therapy in reducing symptoms of children with attention deficit disorder—ADHD. To meet the aim, 20 of children with age range of 7 to 12 years old with attention deficit disorder—hyperactivity were selected in both experimental and control groups, and exposed to the treatment of behavioral family therapy groups and changes in behavior Barkley. Before and after the treatment, they were evaluated according to the scale of the Conner’s Parent Rating Scale-Revised Short Form (CPRS-R: S). Results of multivariate analysis of covariance indicated that there were significant differences between the experimental group who had received family-based behavioral treatments based on changes in behavior Barkley and a control group who had received drug treatment in variables, including conduct problems, learning problems, psychosomatic symptoms, and signs of impulsive hyperactivity, anxiety and hyperactivity (p < 0.01). These results could be guidance for counsel or sand therapists for children with attention deficit disorder—ADHD.
