The Earth’s Free Core Nutation(FCN) causes Earth tides and forced nutation with frequencies close to the FCN that exhibit resonance effects.High-precision superconducting gravimeter(SG) and very long baseline interfe...The Earth’s Free Core Nutation(FCN) causes Earth tides and forced nutation with frequencies close to the FCN that exhibit resonance effects.High-precision superconducting gravimeter(SG) and very long baseline interferometry(VLBI) provide good observation techniques for detecting the FCN parameters.However,some choices in data processing and solution procedures increase the uncertainty of the FCN parameters.In this study,we analyzed the differences and the effectiveness of weight function and ocean tide corrections in the FCN parameter detection using synthetic data,SG data from thirty-one stations,and the 10 celestial pole offset(CPO) series.The results show that significant discrepancies are caused by different computing options for a single SG station.The stacking method,which results in a variation of0.24-5 sidereal days(SDs) in the FCN period(T) and 10^(3)-10^(4) in the quality factor(Q) due to the selection of the weighting function and the ocean tide model(OTM),can effectively suppress this influence.The statistical analysis results of synthetic data shows that although different weight choices,while adjusting the proportion of diurnal tidal waves involved,do not significantly improve the accuracy of fitted FCN parameters from gravity observations.The study evaluated a series of OTMs using the loading correction efficiency.The fitting of FCN parameters can be improved by selecting the mean of appropriate OTMs based on the evaluation results.Through the estimation of the FCN parameters based on the forced nutation,it was found that the weight function P_(1) is more suitable than others,and different CPO series(after 2009) resulted in a difference of 0.4 SDs in the T and of 103 in the Q.We estimated the FCN parameters for SG(T=430.4±1.5 SDs and Q=1.52×10^(4)±2.5×10^(3)) and for VLBI(T=429.8±0.7 SDs,Q=1.88×10^(4)±2.1×10^(3)).展开更多
The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship bet...The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship between K-aberration and word length pattern is developed.展开更多
In this study, we explore the application of ACP (asymptotic curve based and proportionality oriented) Alpha Beta (αβ) Nonlinear Math to analyze arithmetic and radiation transmission data. Specifically, we investiga...In this study, we explore the application of ACP (asymptotic curve based and proportionality oriented) Alpha Beta (αβ) Nonlinear Math to analyze arithmetic and radiation transmission data. Specifically, we investigate the relationship between two variables. The novel approach involves collecting elementary “y” data and subsequently analyzing the asymptotic cumulative or demulative (opposite of cumulative) Y data. In part I, we examine the connection between the common linear numbers and ideal nonlinear numbers. In part II, we delve into the relationship between X-ray energy and the radiation transmission for various thin film materials. The fundamental physical law asserts that the nonlinear change in continuous variable Y is negatively proportional to the nonlinear change in continuous variable X, expressed mathematically as dα = −Kdβ. Here: dα {Y, Yu, Yb} represents the change in Y, with Yu and Yb denoting the upper and baseline asymptote of Y. dβ {X, Xu, Xb} represents the change in X, with Xu and Xb denoting the upper and baseline asymptote of X. K represents the proportionality constant or rate constant, which varies based on equation arrangement. K is the key inferential factor for describing physical phenomena.展开更多
For the underwater long baseline(LBL)positioning systems,the traditional distance intersection algorithm simplifies the sound speed to a constant,and calculates the underwa-ter target position parameters with a nonlin...For the underwater long baseline(LBL)positioning systems,the traditional distance intersection algorithm simplifies the sound speed to a constant,and calculates the underwa-ter target position parameters with a nonlinear iteration.However,due to the complex underwater environment,the sound speed changes with time and space,and then the acoustic propagation path is actually a curve,which inevitably causes some errors to the traditional distance intersection positioning algorithm.To reduce the position error caused by the uncertain underwater sound speed,a new time of arrival(TOA)intersection underwater positioning algorithm of LBL system is proposed.Firstly,combined with the vertical layered model of the underwater sound speed,an implicit positioning model of TOA intersection is constructed through the constant gradient acoustic ray tracing.And then an optimization function based on the overall TOA residual square sum is advanced to solve the position parameters for the underwater target.Moreover,the particle swarm optimization(PSO)algorithm is replaced with the tra-ditional nonlinear least square method to optimize the implicit positioning model of TOA intersection.Compared with the traditional distance intersection positioning model,the TOA intersec-tion positioning model is more suitable for the engineering practice and the optimization algorithm is more effective.Simulation results show that the proposed methods in this paper can effectively improve the positioning accuracy for the underwater target.展开更多
A dedicated GPS buoy is designed for calibration and validation(Cal/Val)of satellite altimeters since 2014.In order to evaluate the accuracy of the sea surface height(SSH)measured by the GPS buoy,twelve campaigns have...A dedicated GPS buoy is designed for calibration and validation(Cal/Val)of satellite altimeters since 2014.In order to evaluate the accuracy of the sea surface height(SSH)measured by the GPS buoy,twelve campaigns have been done within China sea area between 2014 and 2021.In six of these campaigns,two static Global Navigation Satellite System stations were installed at distances of<1 km and 19 km from the buoy to assess how the baseline length influenced the derived SSH from the buoy solutions.The GPS buoy data was processed using the GAMIT/GLOBK software+TRACK module and CSRS-PPP tool to achieve the SSH.The SSH was compared with conventionally tide gauge(TG)data to evaluate the accuracy of the buoy with the standard deviation of the height element.The results showed that the difference in the standard deviation of the SSH from the buoy and the TG was less than 16 mm.The SSHs processed with different ephemeris(Ultra-Rapid,Rapid,Final)were not significantly different.When the baseline length was 19 km,the SSH solution of the GPS buoy performed well,with standard bias of less than 26 mm between the heights measured by the buoy and TG,meaning that the buoy could be used for Cal/Val of altimeters.The bias between the Canadian Spatial Reference System-precise point positioning tool and the TRACK varied a lot,and some of them were over 130 mm.This deemed too high to be useful for Cal/Val of satellite altimeters.Moreover,the GPS buoy solutions processed by GAMIT/GLOBK software+TRACK module were used for in-orbit Cal/Val of HY-2B/C satellites in ten campaigns.The SSH and significant wave height of the altimeters showed good agreements with the GPS buoy solutions.展开更多
It is difficult to quantify and certify the greenhouse gas(GHG)emission reduction in the entire process of a project of carbon capture,utilization and storage(CCUS)-enhanced oil recovery(EOR).Under the methodological ...It is difficult to quantify and certify the greenhouse gas(GHG)emission reduction in the entire process of a project of carbon capture,utilization and storage(CCUS)-enhanced oil recovery(EOR).Under the methodological framework for GHG voluntary emission reduction project,the carbon emission reduction accounting method for CCUS-EOR project was established after examining the accounting boundaries in process links,the baseline emission and project emission accounting methods,and the emission and leakage quantification and prediction models,in order to provide a certification basis for the quantification of GHG emission reduction in the CCUS-EOR project.Based on the data of energy consumption,emission and leakage monitoring of the CCUS-EOR industrial demonstration project in Jilin Oilfield,the net emission reduction efficiency is determined to be about 91.1%at the current storage efficiency of 80%.The accounting and prediction of carbon emission reduction for CCUS-EOR projects with different concentrations and scales indicate that within the project accounting boundary,the certified net emission reduction efficiency of the low-concentration gas source CCUS-EOR projects represented by coal-fired power plants is about 37.1%,and the certified net emission reduction efficiency of the high-concentration gas source CCUS-EOR projects represented by natural gas hydrogen production is about 88.9%.The proposed method is applicable to the carbon emission reduction accounting for CCUS-EOR projects under multiple baseline scenarios during the certification period,which can provide decision-making basis for the planning and deployment of CCUS-EOR projects.展开更多
The source area of the Yellow River(SAYR),located above the Huangheyan hydrological station,is important for ecological preservation and water source conservation in the Yellow River Basin.In this area,the impact of w...The source area of the Yellow River(SAYR),located above the Huangheyan hydrological station,is important for ecological preservation and water source conservation in the Yellow River Basin.In this area,the impact of water conservation projects on the hydrology and the ecological environment is pivotal in protecting water resources and alpine vegetation ecosystems.This study investigates the impact of the Yellow River Source Hydropower Station on the runoff and ecological evolution of the SAYR,along with the underlying mechanism,using extensive datasets encompassing long-term meteorological,hydrological and remote sensing data from various time periods.Results show that,over the long term,precipitation is the primary factor driving runoff variations in the SAYR.Nevertheless,from 1990 to 2020,there is a notably inconsistent relationship between precipitation and runoff.After the completion of the Yellow River Source Hydropower Station in 2001,the water level of Eling Lake experienced and elevation of 2–3 m,leading to a gradual recovery of runoff.In addition,the basin's water balance shifted from a negative to a positive equilibrium,oscillating with changes in lake water levels.Consequently,the overflow zone of the Tangchama alluvial–proluvial fan in the upper reaches of the lakeshore shifted by 500 m,and marsh wetlands expanded by 20.78 km^(2).The increased storage of lakes and groundwater in the SAYR is the key controlling factor for the runoff recovery,changes in the basin's water balance,and enhancements in lakeshore vegetation ecology.Under the geological background of the Qinghai–Tibet Plateau's upliftment and intensified upstream river erosion,the basin experienced a substantial water imbalance due to declining discharge base levels,which is the most critical factor behind runoff attenuation in the SAYR towards the end of the 20th century.The construction of the hydropower station objectively raised the drainage base level of the basin,thereby positively contributing to the preservation of water balance,runoff stability,and the enhancement of swamps and wetlands along the lakeshore.展开更多
BACKGROUND Gastroesophageal reflux disease(GERD)might be either a cause or comorbidity in children with extraesophageal problems especially as refractory respiratory symptoms,without any best methods or criterion for ...BACKGROUND Gastroesophageal reflux disease(GERD)might be either a cause or comorbidity in children with extraesophageal problems especially as refractory respiratory symptoms,without any best methods or criterion for diagnosing it in children.AIM To evaluate the prevalence of extraesophageal GERD using conventional and combined-video,multichannel intraluminal impedance-pH(MII-pH),and to propose novel diagnostic parameters.METHODS The study was conducted among children suspected of extraesophageal GERD at King Chulalongkorn Memorial Hospital between 2019 and 2022.The children underwent conventional and/or combined-video MII-pH.The potential parameters were assessed and receiver operating characteristic was used for the significant parameters.RESULTS Of 51 patients(52.9%males),aged 2.24 years were recruited.The common problems were cough,recurrent pneumonia,and hypersecretion.Using MII-pH,35.3%of the children were diagnosed with GERD by reflux index(31.4%),total reflux events(3.9%),and symptom indices(9.8%)with higher symptom recorded in the GERD group(94 vs 171,P=0.033).In the video monitoring group(n=17),there were more symptoms recorded(120 vs 220,P=0.062)and more GERD(11.8%vs 29.4%,P=0.398)by symptom indices.Longest reflux time and mean nocturnal baseline impedance were significant parameters for diagnosis with receiver operating characteristic areas of 0.907(P=0.001)and 0.726(P=0.014).CONCLUSION The prevalence of extraesophageal GERD in children was not high as expected.The diagnostic yield of symptom indices increased using video monitoring.Long reflux time and mean nocturnal baseline impedance are novel parameters that should be integrated into the GERD diagnostic criteria in children.展开更多
Perioperative myocardial ischemia(PMI) is mainly caused by increasesin sympathetic nervous system activity due to stress,which results incoronary endothelial dysfunction,hence that it is hypothesized thatcaptopril may...Perioperative myocardial ischemia(PMI) is mainly caused by increasesin sympathetic nervous system activity due to stress,which results incoronary endothelial dysfunction,hence that it is hypothesized thatcaptopril may improve PMI.In our study,twenty mongrel dogs wererandomized for four groups;group Ⅰ:control,group Ⅱ:myocardialinfarction (MI) model,Group Ⅲ:MI+partial gastrectomy,group Ⅳ:MI+captopril+partial gastrectomy.Myocardial infarction wasproduced by ligation of left anterior descending coronary artery exceptthe group Ⅰ.In the group Ⅲ and Ⅳ,the hemodynamics,plasmaendothelin (ET) and nitric oxide (NO) on baseline,pre-andpostoperation were investigated two weeks after MI All animals werekilled by overdose anesthetic and their cardiac samples of non-infarction area taken for examining nitric oxide synthase (NOS)mRNA expression levels in vascular endothelial cells.Results:ingroup Ⅲ,the operation decreased the maximal rate of left ventricularpressure rise (LV+dP/dtmax),cardiac index (CI) and plasma No level,and increased left ventricular end diastolic pressure (LVEDP),time-course of isovolumic pressure fall (T constant),total peripheralresistance (TPR) and the levels of ET.In group Ⅳ,40 minutes afteradminstration of captopril,the TPR was decresed,and the t constantwas incresed significantly.The operation attenuated the TPR and Tconstant,but didn’t affect the other values.In situ hybridization it wasshowed that the expression levels of NOS mRNA was the highest ingroup Ⅰ,lower in groups Ⅱ and Ⅳ,and the lowest in group Ⅲ.Conclusions:1.Partial gastrectomy performed after myocardialinfarction may induce left ventricular systolic and diastolic dysfunction,and may produce coronary endothelial dysfunction;2.captopril canimprove left ventricular dysfuction and endothelial dysfunctioninduced by noncardiac operation.展开更多
基金supported by the Open Fund of Hubei Luojia Laboratory (No. 220100033)the Strategic Priority Research Program of Chinese Academy of Sciences (Grant No. XDB41000000)+1 种基金National Natural Science Foundation of China (Grant Nos. 42174108, 41874094, 42192535 and 42242015)the Young Top-notch Talent Cultivation Program of Hubei Province。
文摘The Earth’s Free Core Nutation(FCN) causes Earth tides and forced nutation with frequencies close to the FCN that exhibit resonance effects.High-precision superconducting gravimeter(SG) and very long baseline interferometry(VLBI) provide good observation techniques for detecting the FCN parameters.However,some choices in data processing and solution procedures increase the uncertainty of the FCN parameters.In this study,we analyzed the differences and the effectiveness of weight function and ocean tide corrections in the FCN parameter detection using synthetic data,SG data from thirty-one stations,and the 10 celestial pole offset(CPO) series.The results show that significant discrepancies are caused by different computing options for a single SG station.The stacking method,which results in a variation of0.24-5 sidereal days(SDs) in the FCN period(T) and 10^(3)-10^(4) in the quality factor(Q) due to the selection of the weighting function and the ocean tide model(OTM),can effectively suppress this influence.The statistical analysis results of synthetic data shows that although different weight choices,while adjusting the proportion of diurnal tidal waves involved,do not significantly improve the accuracy of fitted FCN parameters from gravity observations.The study evaluated a series of OTMs using the loading correction efficiency.The fitting of FCN parameters can be improved by selecting the mean of appropriate OTMs based on the evaluation results.Through the estimation of the FCN parameters based on the forced nutation,it was found that the weight function P_(1) is more suitable than others,and different CPO series(after 2009) resulted in a difference of 0.4 SDs in the T and of 103 in the Q.We estimated the FCN parameters for SG(T=430.4±1.5 SDs and Q=1.52×10^(4)±2.5×10^(3)) and for VLBI(T=429.8±0.7 SDs,Q=1.88×10^(4)±2.1×10^(3)).
文摘The study on designs for the baseline parameterization has aroused attention in recent years. This paper focuses on two-level regular designs for the baseline parameterization. A general result on the relationship between K-aberration and word length pattern is developed.
文摘In this study, we explore the application of ACP (asymptotic curve based and proportionality oriented) Alpha Beta (αβ) Nonlinear Math to analyze arithmetic and radiation transmission data. Specifically, we investigate the relationship between two variables. The novel approach involves collecting elementary “y” data and subsequently analyzing the asymptotic cumulative or demulative (opposite of cumulative) Y data. In part I, we examine the connection between the common linear numbers and ideal nonlinear numbers. In part II, we delve into the relationship between X-ray energy and the radiation transmission for various thin film materials. The fundamental physical law asserts that the nonlinear change in continuous variable Y is negatively proportional to the nonlinear change in continuous variable X, expressed mathematically as dα = −Kdβ. Here: dα {Y, Yu, Yb} represents the change in Y, with Yu and Yb denoting the upper and baseline asymptote of Y. dβ {X, Xu, Xb} represents the change in X, with Xu and Xb denoting the upper and baseline asymptote of X. K represents the proportionality constant or rate constant, which varies based on equation arrangement. K is the key inferential factor for describing physical phenomena.
基金supported by the National Natural Science Foundation of China(61903086,61903366,62001115)the Natural Science Foundation of Hunan Province(2019JJ50745,2020JJ4280,2021JJ40133)the Fundamentals and Basic of Applications Research Foundation of Guangdong Province(2019A1515110136).
文摘For the underwater long baseline(LBL)positioning systems,the traditional distance intersection algorithm simplifies the sound speed to a constant,and calculates the underwa-ter target position parameters with a nonlinear iteration.However,due to the complex underwater environment,the sound speed changes with time and space,and then the acoustic propagation path is actually a curve,which inevitably causes some errors to the traditional distance intersection positioning algorithm.To reduce the position error caused by the uncertain underwater sound speed,a new time of arrival(TOA)intersection underwater positioning algorithm of LBL system is proposed.Firstly,combined with the vertical layered model of the underwater sound speed,an implicit positioning model of TOA intersection is constructed through the constant gradient acoustic ray tracing.And then an optimization function based on the overall TOA residual square sum is advanced to solve the position parameters for the underwater target.Moreover,the particle swarm optimization(PSO)algorithm is replaced with the tra-ditional nonlinear least square method to optimize the implicit positioning model of TOA intersection.Compared with the traditional distance intersection positioning model,the TOA intersec-tion positioning model is more suitable for the engineering practice and the optimization algorithm is more effective.Simulation results show that the proposed methods in this paper can effectively improve the positioning accuracy for the underwater target.
文摘A dedicated GPS buoy is designed for calibration and validation(Cal/Val)of satellite altimeters since 2014.In order to evaluate the accuracy of the sea surface height(SSH)measured by the GPS buoy,twelve campaigns have been done within China sea area between 2014 and 2021.In six of these campaigns,two static Global Navigation Satellite System stations were installed at distances of<1 km and 19 km from the buoy to assess how the baseline length influenced the derived SSH from the buoy solutions.The GPS buoy data was processed using the GAMIT/GLOBK software+TRACK module and CSRS-PPP tool to achieve the SSH.The SSH was compared with conventionally tide gauge(TG)data to evaluate the accuracy of the buoy with the standard deviation of the height element.The results showed that the difference in the standard deviation of the SSH from the buoy and the TG was less than 16 mm.The SSHs processed with different ephemeris(Ultra-Rapid,Rapid,Final)were not significantly different.When the baseline length was 19 km,the SSH solution of the GPS buoy performed well,with standard bias of less than 26 mm between the heights measured by the buoy and TG,meaning that the buoy could be used for Cal/Val of altimeters.The bias between the Canadian Spatial Reference System-precise point positioning tool and the TRACK varied a lot,and some of them were over 130 mm.This deemed too high to be useful for Cal/Val of satellite altimeters.Moreover,the GPS buoy solutions processed by GAMIT/GLOBK software+TRACK module were used for in-orbit Cal/Val of HY-2B/C satellites in ten campaigns.The SSH and significant wave height of the altimeters showed good agreements with the GPS buoy solutions.
基金Supported by the PetroChina Science and Technology Project (2021ZZ01-06,2021DJ1101)。
文摘It is difficult to quantify and certify the greenhouse gas(GHG)emission reduction in the entire process of a project of carbon capture,utilization and storage(CCUS)-enhanced oil recovery(EOR).Under the methodological framework for GHG voluntary emission reduction project,the carbon emission reduction accounting method for CCUS-EOR project was established after examining the accounting boundaries in process links,the baseline emission and project emission accounting methods,and the emission and leakage quantification and prediction models,in order to provide a certification basis for the quantification of GHG emission reduction in the CCUS-EOR project.Based on the data of energy consumption,emission and leakage monitoring of the CCUS-EOR industrial demonstration project in Jilin Oilfield,the net emission reduction efficiency is determined to be about 91.1%at the current storage efficiency of 80%.The accounting and prediction of carbon emission reduction for CCUS-EOR projects with different concentrations and scales indicate that within the project accounting boundary,the certified net emission reduction efficiency of the low-concentration gas source CCUS-EOR projects represented by coal-fired power plants is about 37.1%,and the certified net emission reduction efficiency of the high-concentration gas source CCUS-EOR projects represented by natural gas hydrogen production is about 88.9%.The proposed method is applicable to the carbon emission reduction accounting for CCUS-EOR projects under multiple baseline scenarios during the certification period,which can provide decision-making basis for the planning and deployment of CCUS-EOR projects.
基金funded by China Geological Survey Program(DD20230422)and Chinese Academy of Geological Sciences Basic Research Fund Program(SK202214).
文摘The source area of the Yellow River(SAYR),located above the Huangheyan hydrological station,is important for ecological preservation and water source conservation in the Yellow River Basin.In this area,the impact of water conservation projects on the hydrology and the ecological environment is pivotal in protecting water resources and alpine vegetation ecosystems.This study investigates the impact of the Yellow River Source Hydropower Station on the runoff and ecological evolution of the SAYR,along with the underlying mechanism,using extensive datasets encompassing long-term meteorological,hydrological and remote sensing data from various time periods.Results show that,over the long term,precipitation is the primary factor driving runoff variations in the SAYR.Nevertheless,from 1990 to 2020,there is a notably inconsistent relationship between precipitation and runoff.After the completion of the Yellow River Source Hydropower Station in 2001,the water level of Eling Lake experienced and elevation of 2–3 m,leading to a gradual recovery of runoff.In addition,the basin's water balance shifted from a negative to a positive equilibrium,oscillating with changes in lake water levels.Consequently,the overflow zone of the Tangchama alluvial–proluvial fan in the upper reaches of the lakeshore shifted by 500 m,and marsh wetlands expanded by 20.78 km^(2).The increased storage of lakes and groundwater in the SAYR is the key controlling factor for the runoff recovery,changes in the basin's water balance,and enhancements in lakeshore vegetation ecology.Under the geological background of the Qinghai–Tibet Plateau's upliftment and intensified upstream river erosion,the basin experienced a substantial water imbalance due to declining discharge base levels,which is the most critical factor behind runoff attenuation in the SAYR towards the end of the 20th century.The construction of the hydropower station objectively raised the drainage base level of the basin,thereby positively contributing to the preservation of water balance,runoff stability,and the enhancement of swamps and wetlands along the lakeshore.
基金Supported by The Ratchadapiseksompotch Fund,Chulalongkorn University's Faculty of Medicine,King Chulalongkorn Memorial Hospital's Department of Pediatrics,and Chulalongkorn University's Faculty of Medicine(GA64/48).
文摘BACKGROUND Gastroesophageal reflux disease(GERD)might be either a cause or comorbidity in children with extraesophageal problems especially as refractory respiratory symptoms,without any best methods or criterion for diagnosing it in children.AIM To evaluate the prevalence of extraesophageal GERD using conventional and combined-video,multichannel intraluminal impedance-pH(MII-pH),and to propose novel diagnostic parameters.METHODS The study was conducted among children suspected of extraesophageal GERD at King Chulalongkorn Memorial Hospital between 2019 and 2022.The children underwent conventional and/or combined-video MII-pH.The potential parameters were assessed and receiver operating characteristic was used for the significant parameters.RESULTS Of 51 patients(52.9%males),aged 2.24 years were recruited.The common problems were cough,recurrent pneumonia,and hypersecretion.Using MII-pH,35.3%of the children were diagnosed with GERD by reflux index(31.4%),total reflux events(3.9%),and symptom indices(9.8%)with higher symptom recorded in the GERD group(94 vs 171,P=0.033).In the video monitoring group(n=17),there were more symptoms recorded(120 vs 220,P=0.062)and more GERD(11.8%vs 29.4%,P=0.398)by symptom indices.Longest reflux time and mean nocturnal baseline impedance were significant parameters for diagnosis with receiver operating characteristic areas of 0.907(P=0.001)and 0.726(P=0.014).CONCLUSION The prevalence of extraesophageal GERD in children was not high as expected.The diagnostic yield of symptom indices increased using video monitoring.Long reflux time and mean nocturnal baseline impedance are novel parameters that should be integrated into the GERD diagnostic criteria in children.
文摘Perioperative myocardial ischemia(PMI) is mainly caused by increasesin sympathetic nervous system activity due to stress,which results incoronary endothelial dysfunction,hence that it is hypothesized thatcaptopril may improve PMI.In our study,twenty mongrel dogs wererandomized for four groups;group Ⅰ:control,group Ⅱ:myocardialinfarction (MI) model,Group Ⅲ:MI+partial gastrectomy,group Ⅳ:MI+captopril+partial gastrectomy.Myocardial infarction wasproduced by ligation of left anterior descending coronary artery exceptthe group Ⅰ.In the group Ⅲ and Ⅳ,the hemodynamics,plasmaendothelin (ET) and nitric oxide (NO) on baseline,pre-andpostoperation were investigated two weeks after MI All animals werekilled by overdose anesthetic and their cardiac samples of non-infarction area taken for examining nitric oxide synthase (NOS)mRNA expression levels in vascular endothelial cells.Results:ingroup Ⅲ,the operation decreased the maximal rate of left ventricularpressure rise (LV+dP/dtmax),cardiac index (CI) and plasma No level,and increased left ventricular end diastolic pressure (LVEDP),time-course of isovolumic pressure fall (T constant),total peripheralresistance (TPR) and the levels of ET.In group Ⅳ,40 minutes afteradminstration of captopril,the TPR was decresed,and the t constantwas incresed significantly.The operation attenuated the TPR and Tconstant,but didn’t affect the other values.In situ hybridization it wasshowed that the expression levels of NOS mRNA was the highest ingroup Ⅰ,lower in groups Ⅱ and Ⅳ,and the lowest in group Ⅲ.Conclusions:1.Partial gastrectomy performed after myocardialinfarction may induce left ventricular systolic and diastolic dysfunction,and may produce coronary endothelial dysfunction;2.captopril canimprove left ventricular dysfuction and endothelial dysfunctioninduced by noncardiac operation.