The era of Precision Medicine (PM) has entered its execution phase where acquisition of human genome variation data is already leading the charge [1,2]. PM has come a long way to this phase from the Human Genome Pro...The era of Precision Medicine (PM) has entered its execution phase where acquisition of human genome variation data is already leading the charge [1,2]. PM has come a long way to this phase from the Human Genome Project started some 25 years ago [3,4]; it marks the beginning of disease-centric research in the field of biomedical sciences. Other than deliver- ing high-coverage human genomes by millions--of course tai- lored to patients and common diseases--in the next decade or so, what else do we expect to have and what should we be doing to make the best out of PM projects beyond the current expectation of genetics?展开更多
基金supported by the‘‘Strategic Priority Research Program"of the Chinese Academy of Sciences(Grant No.XDA08010304)awarded to JY
文摘The era of Precision Medicine (PM) has entered its execution phase where acquisition of human genome variation data is already leading the charge [1,2]. PM has come a long way to this phase from the Human Genome Project started some 25 years ago [3,4]; it marks the beginning of disease-centric research in the field of biomedical sciences. Other than deliver- ing high-coverage human genomes by millions--of course tai- lored to patients and common diseases--in the next decade or so, what else do we expect to have and what should we be doing to make the best out of PM projects beyond the current expectation of genetics?