<strong>Background:</strong><span style="font-family:;" "=""><span> Oral iron supplements, usually in the form of ferrous salts, are associated with gastric side effect...<strong>Background:</strong><span style="font-family:;" "=""><span> Oral iron supplements, usually in the form of ferrous salts, are associated with gastric side effects, poor compliance and failure of anemia treatment. To make iron more bioavailable, reduce the gastric side effects and increase the patient compliance, newer iron form, Ferric Sodium EDTA, has become available on the market. </span><b><span>Objective:</span></b><span> To assess the change in hemog</span><span>lobin level after iron supplementation with Ferric Sodium EDTA during </span><span>pregnancy. </span><b><span>Materials and Methods:</span></b><span> This is a longitudinal study concerning 337 </span><span>women attending antenatal care in maternity hospitals in the Democratic</span> <span>Republic of Congo from May to December 2020. The study included soci</span><span>odemographic and anthropometric variables along with type of feed, hemoglobin </span><span>level at recruitment and after three weeks of taking iron supplement with</span><span> Ferric Sodium EDTA (Hemoforce Plus Zinc</span></span><sup><span><span><sup></span><span>®</span><span></sup></span></span></sup><span style="font-family:;" "=""><span> syrup). For statistical analysis, we used t-test or ANOVA and chi-square test, the significance being stated at p < 0.05. </span><b><span>Results:</span></b><span> The frequency of pregnancy anemia was 51.4%. The mean </span><span>hemoglobin value of the overall study group was 8.7 ± 0.5 g/dL. The mean</span><span> maternal age and weight were 28.9 ± 6.2 years and 65.3 ± 11.7 kg, respectively. Most pregnant women (83.1%) had a diet consisting of food of plant and animal origin in equal proportions. Mean of Body Mass Index (BMI) was 24.6 ± 4.6 Kg/m</span><sup><span>2</span></sup><span> and 44.3% were overweight and obese. The co-morbidities associated were malaria and intestinal parasitosis found in 45% and 5.9% of cases, </span><span>respectively. After iron treatment with Ferric Sodium EDTA, the average</span><span> hemoglobin level increased to 11.2 g/dL with mean gain of 2.5 g/dL (p < 0.001). Pregnant women with excess weight (≥90 kg) and malaria as a comorbidity achieved a significantly lower mean hemoglobin gain (p = 0.014 and p = 0.022, respectively). Majority of women (91.2%) had not experienced the metallic taste of the syrup. </span><b><span>Conclusion:</span></b><span> Ferric Sodium EDTA as a novel iron formulation (Hemoforce Plus Zinc</span></span><sup><span><span><sup></span><span>®</span><span></sup></span></span></sup><span style="font-family:;" "=""><span>) has shown a rapid increase in hemoglobin levels in pregnant women suffering from anemia. The speedy rise in hemoglobin is related to the property of Ferric Sodium EDTA to enhance the iron absorption by inhibiting the dietary iron inhibitors. Thus, Ferric Sodium </span><span>EDTA should be used as an effective and promising iron supplement in</span><span> pregnant women with iron deficiency anemia.</span></span>展开更多
Iron fortification can cause several biophysicochemical modifications. Those depend on many factors, such as iron fortificant and the food carrier. There were four groups of chips： 1） non-fortified wheat flour chips...Iron fortification can cause several biophysicochemical modifications. Those depend on many factors, such as iron fortificant and the food carrier. There were four groups of chips： 1） non-fortified wheat flour chips （K1）; 2） non-fortified cassava flour chips （K2）; 3） fortified cassava flour chips, each with ZnSO4 30 ppm and NaFe EDTA （K3） 30 ppm and 4） fortified cassava flour chips, each with ZnSO4 50 ppm and NaFe EDTA （K4） 50 ppm. The chips were evaluated for sensory characteristic （color, taste, flavor, and texture）, organoleptic characteristics tested by preference test, as well as zinc and iron contents. Zinc and iron contents were analyzed by Atomic Absorption Spectophotometric method. The results showed that both fortificants did not affect the sensory characteristic of cassava flour chips. The preference test showed that color, taste, and flavor of Kl chips as a control, were mostly liked, but there was no significant difference preference of texture. Moreover, preference test using K2 as control showed that color of K3 was mostly liked, but there was no significant difference preference of taste, flavor and texture. Fortification can increase the contents of zinc and iron in cassava flour chips. The panelist can accept the fortified cassava chips as well as wheat flour chip, as a consequence, both can be a potential way to combat the iron deficiency anemia.展开更多
A new bimetallic cyano-bridged complex, [NdFe(CN)6(DMF)4(H2O)3]H2O (DMF = N,N-dimethylformamide) 1, has been obtained by the reaction of hexacyanoferrate potassium with neodymium (Ⅲ) chloride in H2O/EtOH/DMF (volume ...A new bimetallic cyano-bridged complex, [NdFe(CN)6(DMF)4(H2O)3]H2O (DMF = N,N-dimethylformamide) 1, has been obtained by the reaction of hexacyanoferrate potassium with neodymium (Ⅲ) chloride in H2O/EtOH/DMF (volume ratio: 2:2:1), and its structure was determined by means of single-crystal X-ray diffraction. The compound crystallizes in space group P21/n of monoclinic system with cell parameters: a = 17.646(1), b = 8.9011(3), c = 19.945(1) ? b = 95.835(2)? V = 3116.6(3) ?, Z = 4, Dc = 1.536 g/cm3, Mr = 720.66, F(000) = 1456, m = 2.166 mm-1, R = 0.0386, wR = 0.1120 and S = 1.061. The central Nd (Ⅲ) ion is coordinated by seven oxygen atoms of four DMF molecules and three water molecules and one nitrogen atom of the bridging cyanide in a slightly distorted square-antiprism arrangement, and the Fe (Ⅲ) ion is in an almost octahedral environment coordinated to six cyano-ligands, of which one cyanide ligand bridges the Nd (Ⅲ) ion to form a bimetallic complex. Molecules of complexes in the crystal lattice are held together by hydrogen bonding, forming a three-dimensional framework.展开更多
Experimental results here can give some new insights into the mechanism of selective recovery of scandium and sodium from high alkali Bayer red mud（RM） through sulfation-roasting-leaching process. Effects of roastin...Experimental results here can give some new insights into the mechanism of selective recovery of scandium and sodium from high alkali Bayer red mud（RM） through sulfation-roasting-leaching process. Effects of roasting and leaching conditions including roasting time, roasting temperature, concentrated H_2SO_4 addition, leaching temperature, leaching time and liquid to RM solid ratio on the leaching rates of calcium, iron, aluminum, silicon, sodium, titanium, scandium and gallium were studied and analyzed, suggesting that roasting temperature and roasting time were the two primary constraints on selective recovery of Sc and Na. High leaching temperature also brought a negative effect on the iron leaching rate. Phase transitions and thermal behaviors of sulfated RM indicated that sodium had an inhibitory action on the liberation of SO_2 or SO_3 from metal sulfates, which should follow the decomposition order of TiOSO_4〉Ga_2（SO_4）_3〉Fe_2（SO_4）_3〉NaFe（SO_4）_2〉NaAl（SO_4）_2~Al_2（SO_4）_3〉Na_3Sc（SO_4）_3〉Na_2SO_4〉CaSO_4. After water leaching, solid-liquid separation could be carried out extremely smoothly and 〉95 wt.% Na＋, ~60 wt.% Sc in [Sc（H_2O）_x（SO_4）_n]^（3–2n）（x≤6） with impurities of 0 wt.% Fe^（3＋）, 0 wt.% Ti4＋, 0 wt.% Ga^（3＋）, 7 wt.% Al^（3＋）, ~29 wt.% Ca^（2＋） and ~3 wt.% Si^（4＋） could be leached into leachant under the optimized roasting and leaching conditions. The alkali-free residue obtained could then be employed as iron-making or building materials.展开更多
文摘<strong>Background:</strong><span style="font-family:;" "=""><span> Oral iron supplements, usually in the form of ferrous salts, are associated with gastric side effects, poor compliance and failure of anemia treatment. To make iron more bioavailable, reduce the gastric side effects and increase the patient compliance, newer iron form, Ferric Sodium EDTA, has become available on the market. </span><b><span>Objective:</span></b><span> To assess the change in hemog</span><span>lobin level after iron supplementation with Ferric Sodium EDTA during </span><span>pregnancy. </span><b><span>Materials and Methods:</span></b><span> This is a longitudinal study concerning 337 </span><span>women attending antenatal care in maternity hospitals in the Democratic</span> <span>Republic of Congo from May to December 2020. The study included soci</span><span>odemographic and anthropometric variables along with type of feed, hemoglobin </span><span>level at recruitment and after three weeks of taking iron supplement with</span><span> Ferric Sodium EDTA (Hemoforce Plus Zinc</span></span><sup><span><span><sup></span><span>®</span><span></sup></span></span></sup><span style="font-family:;" "=""><span> syrup). For statistical analysis, we used t-test or ANOVA and chi-square test, the significance being stated at p < 0.05. </span><b><span>Results:</span></b><span> The frequency of pregnancy anemia was 51.4%. The mean </span><span>hemoglobin value of the overall study group was 8.7 ± 0.5 g/dL. The mean</span><span> maternal age and weight were 28.9 ± 6.2 years and 65.3 ± 11.7 kg, respectively. Most pregnant women (83.1%) had a diet consisting of food of plant and animal origin in equal proportions. Mean of Body Mass Index (BMI) was 24.6 ± 4.6 Kg/m</span><sup><span>2</span></sup><span> and 44.3% were overweight and obese. The co-morbidities associated were malaria and intestinal parasitosis found in 45% and 5.9% of cases, </span><span>respectively. After iron treatment with Ferric Sodium EDTA, the average</span><span> hemoglobin level increased to 11.2 g/dL with mean gain of 2.5 g/dL (p < 0.001). Pregnant women with excess weight (≥90 kg) and malaria as a comorbidity achieved a significantly lower mean hemoglobin gain (p = 0.014 and p = 0.022, respectively). Majority of women (91.2%) had not experienced the metallic taste of the syrup. </span><b><span>Conclusion:</span></b><span> Ferric Sodium EDTA as a novel iron formulation (Hemoforce Plus Zinc</span></span><sup><span><span><sup></span><span>®</span><span></sup></span></span></sup><span style="font-family:;" "=""><span>) has shown a rapid increase in hemoglobin levels in pregnant women suffering from anemia. The speedy rise in hemoglobin is related to the property of Ferric Sodium EDTA to enhance the iron absorption by inhibiting the dietary iron inhibitors. Thus, Ferric Sodium </span><span>EDTA should be used as an effective and promising iron supplement in</span><span> pregnant women with iron deficiency anemia.</span></span>
文摘Iron fortification can cause several biophysicochemical modifications. Those depend on many factors, such as iron fortificant and the food carrier. There were four groups of chips： 1） non-fortified wheat flour chips （K1）; 2） non-fortified cassava flour chips （K2）; 3） fortified cassava flour chips, each with ZnSO4 30 ppm and NaFe EDTA （K3） 30 ppm and 4） fortified cassava flour chips, each with ZnSO4 50 ppm and NaFe EDTA （K4） 50 ppm. The chips were evaluated for sensory characteristic （color, taste, flavor, and texture）, organoleptic characteristics tested by preference test, as well as zinc and iron contents. Zinc and iron contents were analyzed by Atomic Absorption Spectophotometric method. The results showed that both fortificants did not affect the sensory characteristic of cassava flour chips. The preference test showed that color, taste, and flavor of Kl chips as a control, were mostly liked, but there was no significant difference preference of texture. Moreover, preference test using K2 as control showed that color of K3 was mostly liked, but there was no significant difference preference of taste, flavor and texture. Fortification can increase the contents of zinc and iron in cassava flour chips. The panelist can accept the fortified cassava chips as well as wheat flour chip, as a consequence, both can be a potential way to combat the iron deficiency anemia.
基金This work was supported by the National Natural Science Foundation of China (No. 20001007 20131020) Natural Science Foundation of the Chinese Academy of Sciences (KJCX2-H3) and Fujian province (2000F006)
文摘A new bimetallic cyano-bridged complex, [NdFe(CN)6(DMF)4(H2O)3]H2O (DMF = N,N-dimethylformamide) 1, has been obtained by the reaction of hexacyanoferrate potassium with neodymium (Ⅲ) chloride in H2O/EtOH/DMF (volume ratio: 2:2:1), and its structure was determined by means of single-crystal X-ray diffraction. The compound crystallizes in space group P21/n of monoclinic system with cell parameters: a = 17.646(1), b = 8.9011(3), c = 19.945(1) ? b = 95.835(2)? V = 3116.6(3) ?, Z = 4, Dc = 1.536 g/cm3, Mr = 720.66, F(000) = 1456, m = 2.166 mm-1, R = 0.0386, wR = 0.1120 and S = 1.061. The central Nd (Ⅲ) ion is coordinated by seven oxygen atoms of four DMF molecules and three water molecules and one nitrogen atom of the bridging cyanide in a slightly distorted square-antiprism arrangement, and the Fe (Ⅲ) ion is in an almost octahedral environment coordinated to six cyano-ligands, of which one cyanide ligand bridges the Nd (Ⅲ) ion to form a bimetallic complex. Molecules of complexes in the crystal lattice are held together by hydrogen bonding, forming a three-dimensional framework.
基金supported by National Natural Science Foundation of China(51234008,51274042,51474028)Beijing Technical Development Project(00012132)China Postdoctoral Science Foundation(2016M590046)
文摘Experimental results here can give some new insights into the mechanism of selective recovery of scandium and sodium from high alkali Bayer red mud（RM） through sulfation-roasting-leaching process. Effects of roasting and leaching conditions including roasting time, roasting temperature, concentrated H_2SO_4 addition, leaching temperature, leaching time and liquid to RM solid ratio on the leaching rates of calcium, iron, aluminum, silicon, sodium, titanium, scandium and gallium were studied and analyzed, suggesting that roasting temperature and roasting time were the two primary constraints on selective recovery of Sc and Na. High leaching temperature also brought a negative effect on the iron leaching rate. Phase transitions and thermal behaviors of sulfated RM indicated that sodium had an inhibitory action on the liberation of SO_2 or SO_3 from metal sulfates, which should follow the decomposition order of TiOSO_4〉Ga_2（SO_4）_3〉Fe_2（SO_4）_3〉NaFe（SO_4）_2〉NaAl（SO_4）_2~Al_2（SO_4）_3〉Na_3Sc（SO_4）_3〉Na_2SO_4〉CaSO_4. After water leaching, solid-liquid separation could be carried out extremely smoothly and 〉95 wt.% Na＋, ~60 wt.% Sc in [Sc（H_2O）_x（SO_4）_n]^（3–2n）（x≤6） with impurities of 0 wt.% Fe^（3＋）, 0 wt.% Ti4＋, 0 wt.% Ga^（3＋）, 7 wt.% Al^（3＋）, ~29 wt.% Ca^（2＋） and ~3 wt.% Si^（4＋） could be leached into leachant under the optimized roasting and leaching conditions. The alkali-free residue obtained could then be employed as iron-making or building materials.
