[Objective] The paper was to summarize the advances in studies of toxi- cological effects of benzopyrene on fish immune system. [Method] With the main im- mune factors as the breakthrough points, the paper summarized ...[Objective] The paper was to summarize the advances in studies of toxi- cological effects of benzopyrene on fish immune system. [Method] With the main im- mune factors as the breakthrough points, the paper summarized the toxicity mecha- nism and pathway of benzopyrene on fish immune system, as well as the toxicity mechanism of other environmental organic pollutants on fish immune toxicity. [Remit] Fish immune system was in the special stage of evolution, the study on effect of benzopyrene on fish immune system has great significance. [Conclusion] The paper provided basis for dealing with the immune toxicity caused by organic pollutants and other environmental factors in aquaculture so as to strengthen fish immunity.展开更多
Se malt cakes containing 300μg selenium were taken up daily to men from high risk area in lung cancer and the influences of Ultraviolet (UV) and Benaopyrene (BαP) induced unscheduled DNA synthesis (UDS) were determi...Se malt cakes containing 300μg selenium were taken up daily to men from high risk area in lung cancer and the influences of Ultraviolet (UV) and Benaopyrene (BαP) induced unscheduled DNA synthesis (UDS) were determined. The Se levels in serum, hair and activity of GSH-px were increased by 89%, 67% and 178%, respectively, after Se-supplementation for half year. In the UV treatment, the ratio of UDS was decreased from the mean values of 2. 47 in the control to 1. 61 (P<0. 05) in the Se-group, In the BaP treatment, furthermore, the elevated Se levels of 78% in serum and 83% in the hair accompanied with 56% high in activity of GSH-px were followed by the Se intake for one year, while the mean value of UDS was reduced from 2. 21 in the control to 1. 47(P< 0. 05) in the group of selenium tested. The blocking effects of UV irradiation and BaP treatment induced UDS of peripheral lymphocytes were showed in the Se-supplementation.展开更多
基金Supported by China Agriculture Research System (CARS-49) National NonprofitInstitute Research Grant of Freshwater Fisheries Research Center,CAFS(2011JBFA16)~~
文摘[Objective] The paper was to summarize the advances in studies of toxi- cological effects of benzopyrene on fish immune system. [Method] With the main im- mune factors as the breakthrough points, the paper summarized the toxicity mecha- nism and pathway of benzopyrene on fish immune system, as well as the toxicity mechanism of other environmental organic pollutants on fish immune toxicity. [Remit] Fish immune system was in the special stage of evolution, the study on effect of benzopyrene on fish immune system has great significance. [Conclusion] The paper provided basis for dealing with the immune toxicity caused by organic pollutants and other environmental factors in aquaculture so as to strengthen fish immunity.
文摘Se malt cakes containing 300μg selenium were taken up daily to men from high risk area in lung cancer and the influences of Ultraviolet (UV) and Benaopyrene (BαP) induced unscheduled DNA synthesis (UDS) were determined. The Se levels in serum, hair and activity of GSH-px were increased by 89%, 67% and 178%, respectively, after Se-supplementation for half year. In the UV treatment, the ratio of UDS was decreased from the mean values of 2. 47 in the control to 1. 61 (P<0. 05) in the Se-group, In the BaP treatment, furthermore, the elevated Se levels of 78% in serum and 83% in the hair accompanied with 56% high in activity of GSH-px were followed by the Se intake for one year, while the mean value of UDS was reduced from 2. 21 in the control to 1. 47(P< 0. 05) in the group of selenium tested. The blocking effects of UV irradiation and BaP treatment induced UDS of peripheral lymphocytes were showed in the Se-supplementation.
