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计算机模拟在物理化学BET多分子层吸附理论教学中的应用 被引量:1
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作者 黄建花 张伟 《大学化学》 CAS 2024年第1期369-376,共8页
BET多分子层吸附理论抽象但应用广泛,BET公式的推导过程涉及较多数学知识,学生很难透彻理解BET公式的物理意义。面对比表面分析仪输出的吸附脱附等温线和比表面积,学生只能生搬硬套,难以达到预期的教学效果。本文利用计算机模拟气体分... BET多分子层吸附理论抽象但应用广泛,BET公式的推导过程涉及较多数学知识,学生很难透彻理解BET公式的物理意义。面对比表面分析仪输出的吸附脱附等温线和比表面积,学生只能生搬硬套,难以达到预期的教学效果。本文利用计算机模拟气体分子在固体表面的吸附脱附过程,通过调整吸附脱附常数,可分别得到第I、II、III类吸附等温线;结合实时可视化使学生能直观看到气体分子在固体表面的吸附脱附动力学,从而能更好地理解BET理论。计算机模拟辅助教学还能活跃课堂气氛,实现教与学互动,激发学生的求知欲和科研兴趣,提高教学质量。 展开更多
关键词 计算机模拟 固体表面 bet公式 吸附-脱附动力学 吸附等温线
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基于改进的BET多层吸附模型的深层页岩吸附气含量测井评价方法
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作者 钟光海 李跃纲 李生杰 《测井技术》 CAS 2024年第1期84-93,共10页
含气量是页岩储层评价的一项关键指标,页岩含气量受温度-压力耦合影响,特别在地层压力较高情况下,准确预测页岩储层吸附气含量较为困难。针对深层页岩气储层高温高压环境下甲烷吸附特性,提出了改进的BET多层吸附模型,建立了一套深层页... 含气量是页岩储层评价的一项关键指标,页岩含气量受温度-压力耦合影响,特别在地层压力较高情况下,准确预测页岩储层吸附气含量较为困难。针对深层页岩气储层高温高压环境下甲烷吸附特性,提出了改进的BET多层吸附模型,建立了一套深层页岩储层吸附气含量测井评价方法。应用该方法对川南深层页岩储层进行含气量评价,结果表明:利用改进的BET多层吸附模型计算的吸附气含量更符合实际地质情况,结合相应层段游离气含量,计算所得的页岩总含气量精度较高,且与现场保压取心获取的总含气量较为一致。基于改进的BET多层吸附模型的吸附气含量评价方法在川南深层页岩气区块具有较好的适应性,可为深层页岩地质甜点评价和资源潜力分析提供技术支撑。 展开更多
关键词 四川盆地 吸附气含量 等温吸附实验 bet吸附 含气量
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High Altitude Frogs (Rana kukonoris) Adopt a Diversified Bethedging Strategy in the Face of Environmental Unpredictability 被引量:1
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作者 Wei CHEN Liqing PENG +3 位作者 Lichun JIANG David A.PIKE Christopher R.FRIESEN Gregory BROWN 《Asian Herpetological Research》 SCIE CSCD 2018年第1期43-49,共7页
Environmental unpredictability can influence strategies of maternal investment among eggs within a clutch. Models predict that breeding females should adopt a diversified bet-hedging strategy in unpredictable environm... Environmental unpredictability can influence strategies of maternal investment among eggs within a clutch. Models predict that breeding females should adopt a diversified bet-hedging strategy in unpredictable environments, but empirical field evidence from Asia is scarce. Here we tested this hypothesis by exploring spatial patterns in egg size along an altitudinal gradient in a frog species (Rana kukunoris) inhabiting the Tibetan Plateau. Within-clutch variability in egg size increased as the environment became variable (e.g., lower mean monthly temperature and mean monthly rainfall at higher altitudes), and populations in environments with more unpredictable rainfall produced eggs that were smaller and more variable in size. We provide support for a diversified bet-hedging strategy in high-altitude environments, which experience dynamic weather patterns and therefore are of unpredictable environmental quality. This strategy may be an adaptive response to lower environmental quality and higher unpredictable environmental variance. Such a strategy should increase the likelihood of breeding success and maximize maternal lifetime fitness by producing offspring that are adapted to current environmental conditions. We speculate that in high-altitude environments prone to physical disturbance, breeding females are unable to consistently produce the optimal egg size due to physiological constraints imposed by environmental conditions (e.g., duration of the active season, food availability). Species and populations whose breeding strategies are adapted to cope with uncertain environmental conditions by adjusting offspring size and therefore quality show a remarkable degree of ability to cope with future climatic changes. 展开更多
关键词 altitude bet-hedging strategy environmental quality egg size within-clutch variation unpredictable environment
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A Corpus-based Contrastive Study on Hedging in English Business Cor-respondences between Chinese English Learners and Native Speakers
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作者 周敏仪 《海外英语》 2013年第1X期261-262,共2页
This is a corpus-based contrastive study projected to find out the differences in using hedges in English business corre spondences between Chinese English learners and native speakers.
关键词 hedgES CORPUS CONTRASTIVE study NS CEL
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An Exploratory Study of Hedging in Chinese ESL Learners' Academic
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作者 陈玮 《海外英语》 2013年第11X期41-43,49,共4页
Hedging, referring to the use of various lexical and syntactic features modifying and mitigating propositions and claims, is extensively employed in effective academic writing. However, the use of hedges seems to be q... Hedging, referring to the use of various lexical and syntactic features modifying and mitigating propositions and claims, is extensively employed in effective academic writing. However, the use of hedges seems to be quite problematic for lots of Chinese ESL learners. In view of the situation, this study explores the use of hedges in academic abstracts by a group of undergraduate English majors in a university in Hainan Province. After analyzing data from a corpus and interviews, several problems have been found in the use of hedging devices of these students, and relevant implications have been drawn to the teaching of hedging in the context, which can help the students produce more effective academic writing and to achieve greater university success. 展开更多
关键词 hedging use of hedgES ACADEMIC abstracts problems
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BET蛋白抑制剂JQ1对MRL/lpr狼疮小鼠外周B细胞分化的影响 被引量:2
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作者 曾珊 肖游君 +6 位作者 邱茜 李昊 徐思琪 王竞男 石茂华 梁柳琴 许韩师 《中国免疫学杂志》 CAS CSCD 北大核心 2023年第7期1345-1350,共6页
目的:探讨BET蛋白抑制剂JQ1对MRL/lpr狼疮小鼠外周B细胞分化的影响及其治疗作用。方法:12周龄MRL/lpr小鼠分别腹腔注射JQ150 mg/(kg·d)或10%DMSO;每2周检测24 h尿蛋白定量;6周后检测血清中尿素氮(BUN)、肌酐(Cr)、补体C3、补体C4、... 目的:探讨BET蛋白抑制剂JQ1对MRL/lpr狼疮小鼠外周B细胞分化的影响及其治疗作用。方法:12周龄MRL/lpr小鼠分别腹腔注射JQ150 mg/(kg·d)或10%DMSO;每2周检测24 h尿蛋白定量;6周后检测血清中尿素氮(BUN)、肌酐(Cr)、补体C3、补体C4、抗ds-DNA抗体、ANA及IgG、IgG1、IgG2a、IgM等免疫球蛋白水平;PAS染色观察肾脏组织病理学改变,免疫荧光染色观察IgG和C3免疫复合物沉积情况。利用流式细胞术检测小鼠B细胞各亚群细胞的比例;RT-qPCR检测脾脏prdm1 mRNA表达水平。结果:与DMSO组相比,JQ1治疗组小鼠24 h尿蛋白定量显著减少,血清BUN、Cr水平明显降低,补体C3、C4水平明显升高,抗ds-DNA抗体、ANA以及IgG、IgG1、IgG2a和IgM等免疫球蛋白水平明显降低;此外,JQ1治疗组小鼠肾小球、肾血管的病理损害程度均明显减轻,肾脏IgG和C3免疫复合物沉积显著减少。同时,JQ1治疗组小鼠脾脏、淋巴结、外周血B细胞中浆细胞和记忆B细胞亚群的比例显著下降;JQ1治疗亦显著抑制狼疮小鼠B细胞内调节浆细胞分化的关键转录因子prdm1 mRNA表达。结论:BET蛋白抑制剂JQ1对MRL/lpr狼疮小鼠具有显著的治疗作用,通过抑制Blimp1表达进而调节浆细胞分化可能是其发挥治疗作用的机制之一。BET蛋白可能是SLE治疗的新靶标。 展开更多
关键词 bet蛋白抑制剂 MRL/lpr狼疮小鼠 B细胞
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BET溴域抑制通过阻断VEGFR2介导的PAK1和eNOS激活抑制糖尿病大鼠视网膜病变机制
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作者 余婧 祝莹 +2 位作者 孙李永眷 许琳 侯桂梅 《临床和实验医学杂志》 2023年第8期791-795,共5页
目的探究BET溴域抑制通过阻断血管内皮生长因子受体2(VEGFR2)介导的p21激活激酶1(PAK1)和内皮型一氧化氮合成酶(eNOS)激活抑制糖尿病大鼠视网膜病变机制。方法选择36只雄性SD大鼠,随机选取10只大鼠作为对照组,余下大鼠采用单次注射链脲... 目的探究BET溴域抑制通过阻断血管内皮生长因子受体2(VEGFR2)介导的p21激活激酶1(PAK1)和内皮型一氧化氮合成酶(eNOS)激活抑制糖尿病大鼠视网膜病变机制。方法选择36只雄性SD大鼠,随机选取10只大鼠作为对照组,余下大鼠采用单次注射链脲霉素60 mg/kg建立糖尿病模型。将建模成功的20只大鼠随机分为模型组和BET抑制组,每组10只。对照组大鼠不建模。BET抑制组大鼠建模后,腹腔注射80 mg·kg^(-1)·d^(-1)剂量的JQ1。使用ZEISS数码显微镜和免疫组织化学分析大鼠视网膜心血管生成。通过蛋白质印迹法分析视网膜屏障功能相关蛋白的表达。通过FITC-葡聚糖泄漏实验检测大鼠内外视网膜屏障完整性。通过RT-qPCR分析大鼠视网膜炎症因子的表达。通过酶联免疫吸附试验试剂盒检测大鼠房水VEGF浓度。通过蛋白质印迹法分析视网膜VEGFR2/PAK1/eNOS的蛋白表达。结果与对照组相比,模型组和BET抑制组视网膜新血管生成量、CD34表达、albumin蛋白表达、内外视网膜FITC-葡聚糖泄漏量、IL-1β、iNOS和ICAM-1 mRNA表达、VEGF浓度、视网膜P-PAK1、P-VEGFR2和eNOS蛋白表达均升高,ZO-1和occludin蛋白表达均降低,差异均有统计学意义(P<0.05);与模型组相比,BET抑制组视网膜新血管生成量、CD34表达、albumin表达、内外视网膜FITC-葡聚糖泄漏量、IL-1β、iNOS和ICAM-1mRNA表达、VEGF浓度、P-PAK1、P-VEGFR2和eNOS蛋白表达均降低,ZO-1和occludin蛋白表达均升高,差异均有统计学意义(P<0.05)。结论BET溴化域通过调节VEGFR2介导的PAK1和eNOS信号通路激活抑制血管生成,降低血管通透性,改善糖尿病大鼠视网膜病变。抑制BET溴化域的策略可能为限制血管生成相关疾病提供一种新的治疗方法。 展开更多
关键词 bet溴域抑制 VEGFR2 PAK1 eNOS 视网膜病变
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COVID‑19 pandemic and the crude oil market risk:hedging options with non‑energy financial innovations 被引量:1
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作者 Afees A.Salisu Kingsley Obiora 《Financial Innovation》 2021年第1期722-740,共19页
This study examines the hedging effectiveness of financial innovations against crude oil investment risks,both before and during the COVID-19 pandemic.We focus on the non-energy exchange traded funds(ETFs)as proxies f... This study examines the hedging effectiveness of financial innovations against crude oil investment risks,both before and during the COVID-19 pandemic.We focus on the non-energy exchange traded funds(ETFs)as proxies for financial innovations given the potential positive correlation between energy variants and crude oil proxies.We employ a multivariate volatility modeling framework that accounts for important statistical features of the non-energy ETFs and oil price series in the computation of optimal weights and optimal hedging ratios.Results show evidence of hedging effectiveness for the financial innovations against oil market risks,with higher hedging performance observed during the pandemic.Overall,we show that sectoral financial innovations provide resilient investment options.Therefore,we propose that including the ETFs in an investment portfolio containing oil could improve risk-adjusted returns,especially in similar financial crisis as witnessed during the pandemic.In essence,our results are useful for investors in the global oil market seeking to maximize risk-adjusted returns when making investment decisions.Moreover,by exploring the role of structural breaks in the multivariate volatility framework,our attempts at establishing robustness for the results reveal that ignoring the same may lead to wrong conclusions about the hedging effectiveness. 展开更多
关键词 Pandemics Financial innovations Energy markets hedging Optimal portfolio
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Hedging in Discourse Analysis
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作者 肖欣 《海外英语》 2015年第12期232-234,共3页
In this article an attempt to enhance the awareness of hedging use in discourse analysis and academic writing is madeby analyzing hedges employed in two comparable texts.The discourse analysis is conducted from"c... In this article an attempt to enhance the awareness of hedging use in discourse analysis and academic writing is madeby analyzing hedges employed in two comparable texts.The discourse analysis is conducted from"content-oriented"hedges and"reader-oriented"hedges.The article suggests that hedging can dampen utterances and statements,weaken the force of what onesays and show politeness to the listeners or readers,which varies from different discourse styles of various genres.discourse marker;hedging;research article;news 展开更多
关键词 DISCOURSE MARKER hedging research ARTICLE NEWS report
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The Relative Ordering of Optimal Hedging Points in a Class of Failure Prone Manufacturing Systems
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作者 俞新贞 宋文忠 《Journal of Southeast University(English Edition)》 EI CAS 1997年第1期114-117,共4页
TheRelativeOrderingofOptimalHedgingPointsinaClassofFailureProneManufacturingSystemsYuXinzhen(俞新贞)SongWenzhon... TheRelativeOrderingofOptimalHedgingPointsinaClassofFailureProneManufacturingSystemsYuXinzhen(俞新贞)SongWenzhong(宋文忠)(Automation... 展开更多
关键词 MANUFACTURING SYSTEM MARKOV chain transition rate SYSTEM state hedging point policy
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Insiders' Hedging for Jump Diffusion Processes with Applications to Index Tracking
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作者 苏小囡 王伟 王文胜 《Journal of Donghua University(English Edition)》 EI CAS 2011年第6期571-575,共5页
The hedging problem for insiders is very important in the financial market.The locally risk minimizing hedging was adopted to solve this problem.Since the market was incomplete,the minimal martingale measure was chose... The hedging problem for insiders is very important in the financial market.The locally risk minimizing hedging was adopted to solve this problem.Since the market was incomplete,the minimal martingale measure was chosen as the equivalent martingale measure.By the F-S decomposition,the expression of the locally risk minimizing strategy was presented.Finally,the local risk minimization was applied to index tracking and its relationship with tracking error variance (TEV)-minimizing strategy was obtained. 展开更多
关键词 jump diffusion processes local risk minimization insiders’ hedging index tracking
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Power Purchase Model of Provincial Grids Based on Diverse Energy Coordination Hedging Optimization
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作者 Dunnan Liu Yujie Xu +3 位作者 Weimin Zeng Jiangping Liu Min Fan Xinming Liu 《Journal of Power and Energy Engineering》 2014年第4期463-469,共7页
Under the background of energy conservation, the grid companies should give priority to consumptive hydropower, wind power and other clean electricity to fulfill their social responsibility and promote the carbon emis... Under the background of energy conservation, the grid companies should give priority to consumptive hydropower, wind power and other clean electricity to fulfill their social responsibility and promote the carbon emission reduction in power industry. But under the current power purchase mode, grid companies must first perform the contract. This is extremely uneconomical and not environmentally friendly. Based on hedging theory, this paper proposes a power purchase optimization model using the strategy of “compression and compensation”. If outer price is lower than the contract price, the grid can compress contract power appropriately, leaving more space for purchasing electricity;if outer price is not attractive enough, the grid should timely improve contract proportion, compensating the deviations of contract caused by "compression". Based on the strategy of "compression and compensation", it can effectively reduce the abandoned wind and water, enhance the economic and social benefits of provincial power grid. 展开更多
关键词 Power PURCHASE OPTIMIZATION hedging "Compression and Compensation" Large-Scale System Decomposition-Coordination
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Optimal Hedging Strategies of Stock Index Futures Based on the Perspective of Information Asymmetry
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作者 Jianhua Guo 《Open Journal of Applied Sciences》 2020年第2期15-24,共10页
Based on two different risk measurement criteria, this article studied the optimal hedging strategies of stock index futures in the case of asymmetric information, and discussed the influence of insider information on... Based on two different risk measurement criteria, this article studied the optimal hedging strategies of stock index futures in the case of asymmetric information, and discussed the influence of insider information on the hedging effect. Through simulation analysis, it can be shown that hedging people with insider information can save hedging costs to a certain extent, which also explains the reason why investors try to obtain corporate information in actual investment activities. 展开更多
关键词 STOCK INDEX FUTURES OPTIMAL hedging Strategy Information Asymmetry
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转录因子T-bet在慢性阻塞性肺疾病发病中作用的研究进展
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作者 陈瑜婷 黄玲 +3 位作者 夏俊杰 邱宇 弋可 王金诚 《基础医学与临床》 2023年第8期1322-1325,共4页
慢性阻塞性肺疾病(COPD)是一种慢性进行性发展的呼吸系统疾病。转录因子T-bet在抗炎作用、免疫调节等方面参与COPD发病的炎性反应及肺功能改变,有望成为防治COPD发病的新靶点,为COPD的靶向研究提供新思路。
关键词 T-bet TH1细胞 TH2细胞 TH17细胞 慢性阻塞性肺疾病
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On discrete time hedging errors in a fractional Black-Scholes model
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作者 WANG Wen-sheng 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2017年第2期211-224,共14页
In this paper we investigate asymptotic behavior of error of a discrete time hedging strategy in a fractional Black-Scholes model in the sense of Wick-ItS-Skorohod integration. The rate of convergence of the hedging e... In this paper we investigate asymptotic behavior of error of a discrete time hedging strategy in a fractional Black-Scholes model in the sense of Wick-ItS-Skorohod integration. The rate of convergence of the hedging error due to discrete-time trading when the true strategy is known for the trader, is investigated. The result provides new statistical tools to study and detect the effect of the long-memory and the Hurst parameter for the error of discrete time hedging. 展开更多
关键词 discrete time hedging Wick-Itö-Skorohod integral rate of convergence weak convergence incomplete market fractional Brownian motion replicate Black-Scholes model
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Hedging Devices used in the Opinion Column'S Editorials of China Daily
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作者 刘善榕 《海外英语》 2019年第4期131-133,共3页
The editorials of the opinion column in a newspaper express the view of its editors. The application of hedging devices isemployed, in order to support the writers' writing. In this study, the data were gathered f... The editorials of the opinion column in a newspaper express the view of its editors. The application of hedging devices isemployed, in order to support the writers' writing. In this study, the data were gathered from 15 editorials in the opinion column ofChina Daily: 5 editorials are about world issues, the other 5 editorials about Chinese social life, and the last 5 editorials are the edu-cational issues popularly discussed in China. The categorization of hedging devices draws from salvager-Meyer's paper Hedges and Textual Communicative Function in Medical English Written Discourse(1994, p. 154) and Mojica(2005, p. 3). Results revealed thatmost writers of the editorials opted to use approximators and modals. Furthermore, the hedging devices used in the selected editori-als on China Daily mainly had three functions: Show respects of the people or organization or in order for protection; in order to pub-lish timely; and make the prediction more reliable. In general, the Chinese writers seem to be conscious to use hedges appropriatelyin order to make their writing more reliable and avoid some arguments or disparagement. 展开更多
关键词 hedging DEVICES APPROXIMATORS and MODALS EDITORIALS China Daily
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Hedging in English Academic Papers in Linguistics Written by Chinese Authors
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作者 林妹妹 《海外英语》 2010年第11X期359-360,共2页
Hedges in academic writing are drawn attention by scholars. Hedging devices enable writers to express their uncertainty con-cerning the factuality of their statements or to indicate deference to their readers. In this... Hedges in academic writing are drawn attention by scholars. Hedging devices enable writers to express their uncertainty con-cerning the factuality of their statements or to indicate deference to their readers. In this paper,ten English linguistic academic articles written by Chinese scholars were chosen for the study. Hedges were categorized to four types. The analysis showed the total number of hedges per category in all articles. The results indicated that modals/probabilities and semi-auxiliaries or epistemic verbs were preferred by Chinese linguists. It is suggested that for non-native English speakers mastery of hedging devices is requisite in their graduate programs. 展开更多
关键词 hedging devices ENGLISH linguistic academic articles CHINESE SCHOLARS
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Mean-Variance Hedging for General Claims in an Incomplete Market: Numeraire Method
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作者 王桂兰 叶中行 《Journal of Shanghai Jiaotong university(Science)》 EI 2003年第2期175-178,共4页
This paper considered the problem of hedging a European call (put) option for a diffusion model where the asset price is influenced by n uncertain factors. The market is thus incomplete implying that perfect hedging i... This paper considered the problem of hedging a European call (put) option for a diffusion model where the asset price is influenced by n uncertain factors. The market is thus incomplete implying that perfect hedging is not possible. To derive a hedging strategy, it follows the approach based on the idea of hedging under a mean-variance criterion suggested by Schweizer. A very simple solution of this hedging problem by using the numeraire method was presented and some examples with explicit solutions were given. 展开更多
关键词 套期保值 平均误差 赔偿金 权利要求 不完全市场买卖 货币汇率 资本资产定价模型
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STUDY ON CONTINUOUS-TIME HEDGING PROBLEM IN INCOMPLETE MARKETS
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作者 LIU Hai-long(刘海龙) +1 位作者 WU Chong-feng(吴冲锋) 《Journal of Shanghai Jiaotong university(Science)》 EI 2002年第1期105-109,共5页
This paper extended the continuous time dynamic hedging theorem for the incomplete markets of Bertsimas, Kogan and Lo’s to the case in which riskless interest rate is not zero. The theorem was then proved with the st... This paper extended the continuous time dynamic hedging theorem for the incomplete markets of Bertsimas, Kogan and Lo’s to the case in which riskless interest rate is not zero. The theorem was then proved with the stochastic dynamic programming theory, by constructing a self financing dynamic strategy that best approximates an arbitrary payoff function in the mean squared sense. When the riskless interest rate is zero, our optimal hedging strategy coincides with the results of Bertsimas, Kogan and Lo,i.e. their results are special cases of ours. 展开更多
关键词 dynamic-hedging INCOMPLETE MARKETS SELF-FINANCING stochastic dynamic PROGRAMMING
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BET蛋白与脑认知功能关系的研究进展
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作者 孟辉 邹广菁 黄伏连 《中南医学科学杂志》 CAS 2023年第1期146-149,共4页
溴结构域和超末端结构域(BET)蛋白能识别乙酰化组蛋白并与之结合,同时与染色质调节因子相互作用或招募转录起始复合物,从而启动基因转录。近几年,BET蛋白抑制剂的合成推进了BET蛋白相关表观遗传学研究。本文综述BET蛋白的结构和功能、BE... 溴结构域和超末端结构域(BET)蛋白能识别乙酰化组蛋白并与之结合,同时与染色质调节因子相互作用或招募转录起始复合物,从而启动基因转录。近几年,BET蛋白抑制剂的合成推进了BET蛋白相关表观遗传学研究。本文综述BET蛋白的结构和功能、BET蛋白抑制剂、BET蛋白在学习和记忆中的作用、BET蛋白在老年痴呆症中的作用以及BET蛋白在药物成瘾中的作用。 展开更多
关键词 bet蛋白 组蛋白乙酰化 学习与记忆 表观遗传学
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