Traditional Chinese Medicine in colorectal cancer treatment:a bibliometrics study and visualization analysis via CiteSpace

Objective:To evaluate the current state of research and areas of interest for traditional Chinese medicine(TCM)in the field of colorectal cancer treatment.Methods:Related papers published between January 1,2012,and November 27,2021,were found using the Web of Science Core Collection Science Citation Index Expanded.Using CiteSpace's network map generation capability,we then determined the top writers,organizations,countries,keywords,co-cited writers,journals,references,and research trends.Results:This investigation yielded a total of 336 relevant papers.China is the most productive country.Shanghai University of Traditional Chinese Medicine is the leading institution.The journal with the most popularity and publishing volume is Evidence-based Complementary and Alternative Medicine.The author with the most citations and centrality is Lin JM.The terms"epithelial-mesenchymal transition,""cell cycle arrest,""apoptosis,"and"autophagy"are highly frequent and have a high betweenness centrality.Conclusion:According to the results,research on natural products,traditional Chinese medicine(TCM)extracts,and the molecular mechanisms of TCM chemical constituents constitutes the primary focus within TCM cancer treatment investigations.In recent years,there has been a surge of interest in exploring the role of gut microbiota in TCM chemical constituents research,particularly in its ability to induce apoptosis and autophagy in tumor cells,thereby suppressing tumor cell proliferation,metastasis,and invasion.However,due to the intricate composition of TCM and existing technical limitations,the underlying principles guiding TCM's efficacy in treating colorectal cancer remain unclear and warrant further investigation.

Outlining the keyword co-occurrence trends in Shuanghuanglian injection research: A bibliometric study using CiteSpace Ⅲ

Objective:To explore the evolvement and new trends in the use of Shuanghuanglian injection(SHLI).Methods:China National Knowledge Infrastructure(CNKI),PubMed,and Embase were extensively searched using the search terms“Shuanghuanglian injection”and“Shuanghuanglian fenzhen”to retrieve articles relevant to SHLI(1992e2020).Retrieved articles were further investigated by two authors to exclude those unrelated to SHLI.The bibliographical references of the included articles were exported as raw data and then treated using the CiteSpace tool to visualize the mapping of the SHLI research domain.Essential clusters and highly frequent keywords were quantified for further analysis.The clusters were automatically labeled by the algorithm of tf*idf for objective analysis.Basic bibliometric features,including article types and yearly trend in article numbers were also determined and discussed.Results:The modules of the keywords of interest presented clear boundaries with a high modularity score(Q=0.73).High-confidence clusters were identified,including bioactivity fingerprint(S=0.99),equal pupils(S=0.91),drug preparation department(S=0.87),difficulty in respiration(S=0.85),peristalsis(0.88),and Danshen powder injection(S=0.94).The characteristic keywords in terms of frequency and burstiness were Shuanghuanglian powder for injection(F=235,B=5.22),SHLI(F=112,B=11.39),and adverse drug reactions(ADRs;F=104,B=7.35).Conclusion:In the field of SHLI study,there are five major topic categories:bioactivity fingerprint;ADR mechanism and cause detection;proper preparation;clinical evidence accumulation;and efficacy in diseases with no effective treatment and combination usage.The trend for using modern methodologies from a science-based perspective to study SHLI will continue to exist.The causes of multi-factorial ADRs may be an important topic for future studies.

Bibliometric study of diabetic retinopathy during 2000-2010 by ISI

AIM: To analyze the progress in diabetic retinopathy (DR) researches between 2000 and 2010 through bibliometric study. METHODS: Using ISI Web of Science database for statistical sources, we retrieved DR literatures during 2000-2010, analyzed 'the number of published articles per year, authors, source publications, subject category, document type, document language, institution and country/region' by bibliometric statistical methods. RESULTS: The total number of published articles that were retrieved for the years during 2000-2010 was 8590. DR researches changed as a linear upward trend, the main researches focused on ophthalmology, endocrine and metabolic diseases. Article was the main document type. Harvard University was the major research institution. CONCLUSION: There has achieved a significant increase in the number of ISI publications and collaborations in DR literatures from 2000 to 2010. With the rising of the number of diabetes in the world, diabetic retinopathy has become a focus of scientific researches.

Artificial Neural Networks in Risk Management: A Bibliometric Study

This study presents a bibliometric analysis of Artificial Neural Networks in Risk Management.The study considered articles from the I.S.I.Web of Knowledge and Scopus databases,Identification of publishers,countries,periodicals and the keywords most frequently cited.We used the CiteSpace® software to analyze this material,which provides a set of features to support bibliometrics,including the reference maps.This study provides data collection on Artificial Neural Networks applied to risk management.The number of works identified in this study is significant,and in the last ten years,the number of citations has increased.We did not identify the increase in paper count within the same period.

Scientific publications in nursing journals from East Asia:A survey of literature

Background:East Asia is one of the most important economy and research force in the world.However,the trend of published articles in various areas of East Asia has not been reported.Methods:We used PubMed and Web of Science databases to search for articles published from China,South Korea,and Japan in 59 nursing journals,from January 2008 to December 2017.Results:The results indicated that Journal of Clinical Nursing is the most popular journal in East Asia and the number of articles published in China has shown a steady upward trend,surpassing Japan and South Korea(from 204 in 2008 to 320 in 2017).South Korea has increased rapidly since 2013(from 65 in 2013 to 144 in 2017).Conclusion:We conclude that China is the most influenced country with the largest number of articles in the field of nursing in East Asia.It is worth noting that the number of articles published in Japan has been slowly declining since 2015.

Fifty-year of Global Research in Calendula Officinalis L.(1971−2021):A Bibliometric Study

Background:Calendula officinalis L.(Compositae)is a Mediterranean annual plant widely used for its versatile biological activities.Objective:A bibliometric study of research data conducted from 1971 to 2021 was conducted.Methods:Bibliographic data was retrieved from the Scopus database and analyzed using VOSviewer and MS Excel.Polynomial regression was used to assess the annual production of research documents related to C.officinalis.Results:A total of 1,252 journal articles and conference papers were published by 4,452 authors,originated from 98 countries and disseminated in 706 sources.Iran(n=131),Brazil(n=119),India(n=113),Poland(n=112),and Italy(n=72)are the top-publishing countries.Journal of Ethnopharmacology is the top-cited journal,while Italy is the top-cited country.Steady growth was observed in the last fifty years,from 1971 to 2021.The anti-inflammatory,wound-healing,and anti-microbial properties are among the most prolific studies that have been conducted on this plant.Extensive research has been carried out on antioxidant compounds,terpenes,and volatile oils.Skin care and wound healing are the most common clinical applications.Co-citation analysis,keywords co-occurrence,and bibliographic coupling revealed diverse knowledge structures and intellectual dynamics.Conclusion:This comprehensive bibliometric study indicates that Calendula officinalis received significant re-search.The structured information may help understand research trends and locate this plant’s research hot spots and gaps.

Assessment of public health research output by Bangladeshi authors:A scientometric study

The main objective of the study is to assess the growth and expansion of public health(PH)research works by Bangladeshi authors from various perspectives such as quantum of growth,patterns of collaboration, and productivity of authorship, among others. The present research uses a scientometric technique to examine secondary literature. Between 2000 and 2015, 871literature by Bangladeshi writers and 3,71,389 literature by worldwide authors on PH were retrieved from the Scopus database and evaluated using quantitative indicators to study growth and development from various perspectives. The highest growth in terms of the number of publications has been observed in the year 2015(133) and the lowest in 2001(10). The PR(Percent of Growth Rate) shows that 2001 was the deepest decreasing year(-38%) whereas 2002was the most increasing year(90%). During the study, RGR(Relative Growth Rate) values of Bangladeshi contributions to PH literature varied from 0.16 to 0.55, with an average of 0.27. The CC(Collaborative Coefficient) value indicates that during the research period, there was a substantial amount of collaboration among the authors. At the same time, the PPA(Productivity Per Author) value(0.31) denotes that throughout the era, each Bangladeshi author produced less than half of a publication per year. The mean Activity Index(AI) during 2000-2015 was 89.14,which reflects lower activity than the world’s average in PH literature. It was also observed that research productivity in public health of Bangladesh follows Lotka’s inverse rule of author production. According to the findings, there is a strong link between public health research output in emerging and developed nations.