This paper aims to enhance the compression capacity of underwater cylindrical shells by adopting the corrugated sandwich structure of cuttlebone.The cuttlebone suffers uniaxial external compression,while underwater cy...This paper aims to enhance the compression capacity of underwater cylindrical shells by adopting the corrugated sandwich structure of cuttlebone.The cuttlebone suffers uniaxial external compression,while underwater cylindrical shells are in a biaxial compressive stress state.To suit the biaxial compressive stress state,a novel bidirectional corrugated sandwich structure is proposed to improve the bearing capacity of cylindrical shells.The static and buckling analysis for the sandwich shell and the unstiffened cylindrical shell with the same volume-weight ratio are studied by numerical simulation.It is indicated that the proposed sandwich shell can effectively reduce the ratio between circumferential and axial stress from 2 to 1.25 and improve the critical buckling load by about 1.63 times.Numerical simulation shows that optimizing and adjusting the structural parameters could significantly improve the advantage of the sandwich shell.Then,the hydrostatic pressure tests for shell models fabricated by 3D printing are carried out.According to the experimental results,the overall failure position of the sandwich shell is at the center part of the sandwich shell.It has been found the average critical load of the proposed sandwich shell models exceeds two times that of the unstiffened shell models.Hence,the proposed bio-inspired bidirectional corrugated sandwich structure can significantly enhance the pressure resistance capability of cylindrical shells.展开更多
Typical application scenarios,such as vehicle to grid(V2G)and frequency regulation,have imposed significant long-life demands on lithium-ion batteries.Herein,we propose an advanced battery life-extension method employ...Typical application scenarios,such as vehicle to grid(V2G)and frequency regulation,have imposed significant long-life demands on lithium-ion batteries.Herein,we propose an advanced battery life-extension method employing bidirectional pulse charging(BPC)strategy.Unlike traditional constant current charging methods,BPC strategy not only achieves comparable charging speeds but also facilitates V2G frequency regulation simultaneously.It significantly enhances battery cycle ampere-hour throughput and demonstrates remarkable life extension capabilities.For this interesting conclusion,adopting model identification and postmortem characterization to reveal the life regulation mechanism of BPC:it mitigates battery capacity loss attributed to loss of lithium-ion inventory(LLI)in graphite anodes by intermittently regulating the overall battery voltage and anode potential using a negative charging current.Then,from the perspective of internal side reaction,the life extension mechanism is further revealed as inhibition of solid electrolyte interphase(SEI)and lithium dendrite growth by regulating voltage with a bidirectional pulse current,and a semi-empirical life degradation model combining SEI and lithium dendrite growth is developed for BPC scenarios health management,the model parameters are identified by genetic algorithm with the life simulation exhibiting an accuracy exceeding 99%.This finding indicates that under typical rate conditions,adaptable BPC strategies can extend the service life of LFP battery by approximately 123%.Consequently,the developed advanced BPC strategy offers innovative perspectives and insights for the development of long-life battery applications in the future.展开更多
Objective To investigate the causal relationships between plasma metabolites and osteoporosis via Mendelian randomization(MR) analysis.Methods Bidirectional MR was used to analyze pooled data from different genome-wid...Objective To investigate the causal relationships between plasma metabolites and osteoporosis via Mendelian randomization(MR) analysis.Methods Bidirectional MR was used to analyze pooled data from different genome-wide association studies(GWAS). The causal effect of plasma metabolites on osteoporosis was estimated using the inverse variance weighted method, intersections of statistically significant metabolites obtained from different sources of osteoporosis-related GWAS aggregated data was determined, and then sensitivity analysis was performed on these metabolites. Heterogeneity between single nucleotide polymorphisms was evaluated by Cochran's Q test. Horizontal pleiotropy was assessed through the application of the MR-Egger intercept method and the MRPRESSO method. The causal effect of osteoporosis on plasma metabolites was also evaluated using the inverse variance weighted method. Additionally, pathway analysis was conducted to identify potential metabolic pathways involved in the regulation of osteoporosis.Results Primary analysis and sensitivity analysis showed that 77 and 61 plasma metabolites had a causal relationship with osteoporosis from the GWAS data in the GCST90038656 and GCST90044600 datasets, respectively. Five common metabolites were identified via intersection. X-13684 levels and the glucose-to-maltose ratio were negatively associated with osteoporosis, whereas glycoursodeoxycholate levels and arachidoylcarnitine(C20) levels were positively associated with osteoporosis(all P < 0.05). The relationship between X-11299 levels and osteoporosis showed contradictory results(all P < 0.05). Pathway analysis indicated that glycine, serine, and threonine metabolism, valine, leucine, and isoleucine biosynthesis, galactose metabolism, arginine biosynthesis, and starch and sucrose metabolism pathways were participated in the development of osteoporosis.Conclusion We found a causal relationship between plasma metabolites and osteoporosis. These results offer novel perspectives with important implications for targeted metabolite-focused interventions in the management of osteoporosis.展开更多
This study delves into the formation dynamics of alliances within a closed-loop supply chain(CLSC)that encom-passes a manufacturer,a retailer,and an e-commerce platform.It leverages Stackelberg game for this explorati...This study delves into the formation dynamics of alliances within a closed-loop supply chain(CLSC)that encom-passes a manufacturer,a retailer,and an e-commerce platform.It leverages Stackelberg game for this exploration,contrasting the equilibrium outcomes of a non-alliance model with those of three differentiated alliance models.The non-alliance model acts as a crucial benchmark,enabling the evaluation of the motivations for various supply chain entities to engage in alliance formations.Our analysis is centered on identifying the most effective alliance strategies and establishing a coordination within these partnerships.We thoroughly investigate the consequences of diverse alliance behaviors,bidirectional free-riding and cost-sharing,and the resultant effects on the optimal decision-making among supply chain actors.The findings underscore several pivotal insights:(1)The behavior of alliances within the supply chain exerts variable impacts on the optimal pricing and demand of its members.In comparison to the non-alliance(D)model,the manufacturer-retailer(MR)and manufacturer-e-commerce platform(ME)alliances significantly lower both offline and online resale prices for new and remanufactured goods.This adjustment leads to an enhanced demand for products via the MR alliance’s offline outlets and the ME alliance’s online platforms,thereby augmenting the profits for those within the alliance.Conversely,retailer-e-commerce platform(ER)alliance tends to increase the optimal retail price and demand across both online and offline channels.Under specific conditions,alliance behavior can also increase the profits of non-alliance members,and the profits derived through alliance channels also exceed those from non-alliance channels.(2)The prevalence of bidirectional free-riding behavior largely remains constant across different alliance configurations.Across these models,bidirectional free-riding typically elevates the equilibrium prices in offline channel while negatively affecting the equilibrium prices in other channel.(3)The effect of cost-sharing shows relative uniformity across the various alliance models.Across all configurations,cost-sharing tends to reduce the manufacturer’s profits.Nonetheless,alliances initiated by the manufacturer can counteract these negative impacts,providing a strategic pathway to bolster CLSC profitability.展开更多
Since backlash nonlinearity is inevitably existing in actuators for bidirectional stabilization system of allelectric tank,it behaves more drastically in high maneuvering environments.In this work,the accurate trackin...Since backlash nonlinearity is inevitably existing in actuators for bidirectional stabilization system of allelectric tank,it behaves more drastically in high maneuvering environments.In this work,the accurate tracking control for bidirectional stabilization system of moving all-electric tank with actuator backlash and unmodeled disturbance is solved.By utilizing the smooth adaptive backlash inverse model,a nonlinear robust adaptive feedback control scheme is presented.The unknown parameters and unmodelled disturbance are addressed separately through the derived parametric adaptive function and the continuous nonlinear robust term.Because the unknown backlash parameters are updated via adaptive function and the backlash effect can be suppressed successfully by inverse operation,which ensures the system stability.Meanwhile,the system disturbance in the high maneuverable environment can be estimated with the constructed adaptive law online improving the engineering practicality.Finally,Lyapunov-based analysis proves that the developed controller can ensure the tracking error asymptotically converges to zero even with unmodeled disturbance and unknown actuator backlash.Contrast co-simulations and experiments illustrate the advantages of the proposed approach.展开更多
Diabetes mellitus and depression exhibit a complex bidirectional relationship that profoundly impacts patient health and quality of life.This review explores the physiological mechanisms,including inflammation,oxidati...Diabetes mellitus and depression exhibit a complex bidirectional relationship that profoundly impacts patient health and quality of life.This review explores the physiological mechanisms,including inflammation,oxidative stress,and neu-roendocrine dysregulation,that link these conditions.Psychosocial factors such as social support and lifestyle choices also contribute significantly.Epidemiological insights reveal a higher prevalence of depression among diabetics and an in-creased risk of diabetes in depressed individuals,influenced by demographic variables.Integrated management strategies combining mental health asse-ssments and personalized treatments are essential.Future research should focus on longitudinal and multi-omics studies to deepen understanding and improve therapeutic outcomes.展开更多
Breast cancer is a significant threat to the global population,affecting not only women but also a threat to the entire population.With recent advancements in digital pathology,Eosin and hematoxylin images provide enh...Breast cancer is a significant threat to the global population,affecting not only women but also a threat to the entire population.With recent advancements in digital pathology,Eosin and hematoxylin images provide enhanced clarity in examiningmicroscopic features of breast tissues based on their staining properties.Early cancer detection facilitates the quickening of the therapeutic process,thereby increasing survival rates.The analysis made by medical professionals,especially pathologists,is time-consuming and challenging,and there arises a need for automated breast cancer detection systems.The upcoming artificial intelligence platforms,especially deep learning models,play an important role in image diagnosis and prediction.Initially,the histopathology biopsy images are taken from standard data sources.Further,the gathered images are given as input to the Multi-Scale Dilated Vision Transformer,where the essential features are acquired.Subsequently,the features are subjected to the Bidirectional Long Short-Term Memory(Bi-LSTM)for classifying the breast cancer disorder.The efficacy of the model is evaluated using divergent metrics.When compared with other methods,the proposed work reveals that it offers impressive results for detection.展开更多
Two-dimensional(2D)WSe_(2)has received increasing attention due to its unique optical properties and bipolar behavior.Several WSe_(2)-based heterojunctions exhibit bidirectional rectification characteristics,but most ...Two-dimensional(2D)WSe_(2)has received increasing attention due to its unique optical properties and bipolar behavior.Several WSe_(2)-based heterojunctions exhibit bidirectional rectification characteristics,but most devices have a lower rectification ratio.In this work,the Bi_(2)O_(2)Se/WSe_(2)heterojunction prepared by us has a typeⅡband alignment,which can vastly suppress the channel current through the interface barrier so that the Bi_(2)O_(2)Se/WSe_(2)heterojunction device has a large rectification ratio of about 10^(5).Meanwhile,under different gate voltage modulation,the current on/off ratio of the device changes by nearly five orders of magnitude,and the maximum current on/off ratio is expected to be achieved 106.The photocurrent measurement reveals the behavior of recombination and space charge confinement,further verifying the bidirectional rectification behavior of heterojunctions,and it also exhibits excellent performance in light response.In the future,Bi_(2)O_(2)Se/WSe_(2)heterojunction field-effect transistors have great potential to reduce the volume of integrated circuits as a bidirectional controlled switching device.展开更多
Unsupervised methods based on density representation have shown their abilities in anomaly detection,but detection performance still needs to be improved.Specifically,approaches using normalizing flows can accurately ...Unsupervised methods based on density representation have shown their abilities in anomaly detection,but detection performance still needs to be improved.Specifically,approaches using normalizing flows can accurately evaluate sample distributions,mapping normal features to the normal distribution and anomalous features outside it.Consequently,this paper proposes a Normalizing Flow-based Bidirectional Mapping Residual Network(NF-BMR).It utilizes pre-trained Convolutional Neural Networks(CNN)and normalizing flows to construct discriminative source and target domain feature spaces.Additionally,to better learn feature information in both domain spaces,we propose the Bidirectional Mapping Residual Network(BMR),which maps sample features to these two spaces for anomaly detection.The two detection spaces effectively complement each other’s deficiencies and provide a comprehensive feature evaluation from two perspectives,which leads to the improvement of detection performance.Comparative experimental results on the MVTec AD and DAGM datasets against the Bidirectional Pre-trained Feature Mapping Network(B-PFM)and other state-of-the-art methods demonstrate that the proposed approach achieves superior performance.On the MVTec AD dataset,NF-BMR achieves an average AUROC of 98.7%for all 15 categories.Especially,it achieves 100%optimal detection performance in five categories.On the DAGM dataset,the average AUROC across ten categories is 98.7%,which is very close to supervised methods.展开更多
The rate equation model is setup for the signal gain, pump absorption and output noise spectrum of bidirectional EDFA (Bi EDFA) including numbers of signals, pumps of arbitrary direction, amplified spontaneous emissi...The rate equation model is setup for the signal gain, pump absorption and output noise spectrum of bidirectional EDFA (Bi EDFA) including numbers of signals, pumps of arbitrary direction, amplified spontaneous emission (ASE) and inherent loss. The influence of erbium doped fiber length, input signal power, pump style and pump power on the gain characteristics of Bi EDFA is analyzed. Forward and backward noise figure for different pump style versus bidirectional input signal power is investigated.展开更多
To study the seismic performance of double-skin steelconcrete composite box( DSCB) piers, a total of 11 DSCB pier specimens were tested under bidirectional cyclic loading. The effects of the loading pattern, the ste...To study the seismic performance of double-skin steelconcrete composite box( DSCB) piers, a total of 11 DSCB pier specimens were tested under bidirectional cyclic loading. The effects of the loading pattern, the steel plate thickness, the axial load ratio, the slenderness ratio and the aspect ratio were taken into consideration. The damage evolution process and failure modes of the tested specimens are presented in detail. Test results are also discussed in terms of the hysteretic curve, skeleton curve, ductility and energy dissipation capacity of DSCB pier specimens. It can be concluded that the hysteretic performance of DSCB piers in one direction is affected and weakened by the cyclic loading in the other direction. DSCB piers under bidirectional cyclic loading exhibit good performance in terms of load carrying capacity, ductility, and energy dissipation capacity. Overall, DSCB piers can meet the basic aseismic requirements. The research results can be taken as a reference for using DSCB piers as high piers in bridges in strong earthquakeprone areas.展开更多
The multiple classifier system (MCS), composed of multiple diverse classifiers or feed-forward neural networks, can significantly improve the classification or generalization ability of a single classifier. Enlighte...The multiple classifier system (MCS), composed of multiple diverse classifiers or feed-forward neural networks, can significantly improve the classification or generalization ability of a single classifier. Enlightened by the fundamental idea of MCS, the ensemble is introduced into the quick learning for bidirectional associative memory (QLBAM) to construct a BAM ensemble, for improving the storage capacity and the error-correction capability without destroying the simple structure of the component BAM. Simulations show that, with an appropriate "overproduce and choose" strategy or "thinning" algorithm, the proposed BAM ensemble significantly outperforms the single QLBAM in both storage capacity and noise-tolerance capability.展开更多
In this paper we propose a new discrete bidirectional associative memory (DBAM) which is derived from our previous continuous linear bidirectional associative memory (LBAM). The DBAM performs bidirectionally the opti...In this paper we propose a new discrete bidirectional associative memory (DBAM) which is derived from our previous continuous linear bidirectional associative memory (LBAM). The DBAM performs bidirectionally the optimal associative mapping proposed by Kohonen. Like LBAM and NBAM proposed by one of the present authors,the present BAM ensures the guaranteed recall of all stored patterns,and possesses far higher capacity compared with other existing BAMs,and like NBAM, has the strong ability to suppress the noise occurring in the output patterns and therefore reduce largely the spurious patterns. The derivation of DBAM is given and the stability of DBAM is proved. We also derive a learning algorithm for DBAM,which has iterative form and make the network learn new patterns easily. Compared with NBAM the present BAM can be easily implemented by software.展开更多
This paper reports on an investigation of the seismic response of base-isolated reinforced concrete buildings, which considers various isolation system parameters under bidirectional near-fault and far-fault motions. ...This paper reports on an investigation of the seismic response of base-isolated reinforced concrete buildings, which considers various isolation system parameters under bidirectional near-fault and far-fault motions. Three-dimensional models of 4-, 8-, and 12-story base-isolated buildings with nonlinear effects in the isolation system and the superstructure are investigated, and nonlinear response history analysis is carried out. The bounding values of isolation system properties that incorporate the aging effect of isolators are also taken into account, as is the current state of practice in the design and analysis of base-isolated buildings. The response indicators of the buildings are studied for near-fault and far-fault motions weight-scaled to represent the design earthquake (DE) level and the risk-targeted maximum considered earthquake (MCER) level. Results of the nonlinear response history analyses indicate no structural damage under DE-level motions for near-fault and far-fault motions and for MCER-level far-fault motions, whereas minor structural damage is observed under MCER- level near-fault motions. Results of the base-isolated buildings are compared with their fixed-base counterparts. Significant reduction of the superstructure response of the 12-story base-isolated building compared to the fixed-base condition indicates that base isolation can be effectively used in taller buildings to enhance performance. Additionally, the applicability of a rigid superstructure to predict the isolator displacement demand is also investigated. It is found that the isolator displacements can be estimated accurately using a rigid body model for the superstructure for the buildings considered.展开更多
In traditional networks , the authentication is performed by certificate authoritys(CA),which can't be built in distributed mobile Ad Hoc Networks however. In this pa per, we propose a fully self-organized public k...In traditional networks , the authentication is performed by certificate authoritys(CA),which can't be built in distributed mobile Ad Hoc Networks however. In this pa per, we propose a fully self-organized public key management based on bidirectional trust model without any centralized authority that allows users to generate their public-private key pairs, to issue certificates, and the trust relation spreads rationally according to the truly human relations. In contrast with the traditional self-organized public-key management, the average certificates paths get more short, the authentication passing rate gets more high and the most important is that the bidirectional trust based model satisfys the trust re quirement of hosts better.展开更多
In this study,dynamic responses of two buildings connected by viscoelastic dampers under bidirectional excitations are extensively investigated.The two buildings are a 10-story building and a 16-story building,with th...In this study,dynamic responses of two buildings connected by viscoelastic dampers under bidirectional excitations are extensively investigated.The two buildings are a 10-story building and a 16-story building,with the shorter building on the left.Viscoelastic dampers are installed at all fl oors of the shorter building.Equations of motion are formulated using a fractional derivative model to represent the viscoelastic dampers.Three cases are considered with mass eccentricities at 0,10% and-10% with respect to the dimensions of the buildings.The responses of the buildings are numerically predicted at different damper properties.The simulation results indicated that the maximum horizontal responses of the buildings without eccentricities are signifi cantly mitigated.However,torsional effects are adversely increased.For asymmetric buildings,the effectiveness of the connecting dampers is affected by building eccentricities.As a result,mass eccentricities must be taken into account in damper selection.When compared with vibrations induced by unidirectional excitations,bidirectional excitations can increase the responses of coupled asymmetric buildings.In addition,installing dampers only at the top fl oor of the shorter building may cause a sudden change in lateral stiffness of the taller building.Consequently,the story shear envelopes of the taller building are changed.展开更多
Bidirectional Dijkstra algorithm whose time complexity is 8O(n~2) is proposed. The theory foundation is that the classical Dijkstra algorithm has not any directional feature during searching the shortest path. The alg...Bidirectional Dijkstra algorithm whose time complexity is 8O(n~2) is proposed. The theory foundation is that the classical Dijkstra algorithm has not any directional feature during searching the shortest path. The algorithm takes advantage of the adjacent link and the mechanism of bidirectional search, that is, the algorithm processes the positive search from start point to destination point and the negative search from destination point to start point at the same time. Finally, combining with the practical application of route-planning algorithm in embedded real-time vehicle navigation system (ERTVNS), one example of its practical applications is given, analysis in theory and the experimental results show that compared with the Dijkstra algorithm, the new algorithm can reduce time complexity, and guarantee the searching precision, it satisfies the needs of ERTVNS.展开更多
Multiple cellular components, including neuronal, glial and endothelial ceils, are involved in the sophis- ticated pathological processes following central nervous system injury. The pathological process cannot reduce...Multiple cellular components, including neuronal, glial and endothelial ceils, are involved in the sophis- ticated pathological processes following central nervous system injury. The pathological process cannot reduce damage or improve functional recovery by merely targeting the molecular mechanisms of neuronal cell death after central nerve system injuries. Eph receptors and ephrin ligands have drawn wide attention since the discovery of their extensive distribution and unique bidirectional signaling between astrocytes and neurons. The roles of Eph/ephrin bidirectional signaling in the developmental processes have been re- ported in previous research. Recent observations suggest that Eph/ephrin bidirectional signaling continues to be expressed in most regions and cell types in the adult central nervous system, playing diverse roles. The Eph/ephrin complex mediates neurogenesis and angiogenesis, promotes glial scar formation, regulates endocrine levels, inhibits myelin formation and aggravates inflammation and nerve pain caused by injury. ~lhe interaction between Eph and ephrin is also considered to be the key to angiogenesis. This review focus- es on the roles of Eph/ephrin bidirectional signaling in the repair of central nervous system injuries.展开更多
Modelling of bidirectional full bridge DC-DC converter as one of the most applicable converters has received significant attention. Mathematical modelling reduces the simulation time in comparison with detailed circui...Modelling of bidirectional full bridge DC-DC converter as one of the most applicable converters has received significant attention. Mathematical modelling reduces the simulation time in comparison with detailed circuit response;moreover it is convenient for controller design purpose. Due to simple and effective methodology, average state space is the most common method among the modelling methods. In this paper a bidirectional full bridge converter is modelled by average state space and for each mode of operations a controller is designed. Attained mathematical model results are in a close agreement with detailed circuit simulation.展开更多
An effective approach is presented to extract welds from real-time radiographs, Firstly an algorithm based on an adaptive bidirectional threshold was proposed to segment the gradient image into ternary image, and then...An effective approach is presented to extract welds from real-time radiographs, Firstly an algorithm based on an adaptive bidirectional threshold was proposed to segment the gradient image into ternary image, and then the bidirectional accumulator Hough Transform was developed to extract weld edges from the ternary image. Different values of the coefficient proposed in the threshold algorithm were tested, and the proposed approach was applied to extract welds from real-time radiographic images of different types of welds with defects. Results show that the proposed method is adaptive and effective to extract welds from real-time radiographs of linear welds.展开更多
基金financially supported by the National Key Research and Development Program of China(Grant No.2022YFB2602800)the National Natural Science Foundation of China(Grant Nos.51879231,51679214)。
文摘This paper aims to enhance the compression capacity of underwater cylindrical shells by adopting the corrugated sandwich structure of cuttlebone.The cuttlebone suffers uniaxial external compression,while underwater cylindrical shells are in a biaxial compressive stress state.To suit the biaxial compressive stress state,a novel bidirectional corrugated sandwich structure is proposed to improve the bearing capacity of cylindrical shells.The static and buckling analysis for the sandwich shell and the unstiffened cylindrical shell with the same volume-weight ratio are studied by numerical simulation.It is indicated that the proposed sandwich shell can effectively reduce the ratio between circumferential and axial stress from 2 to 1.25 and improve the critical buckling load by about 1.63 times.Numerical simulation shows that optimizing and adjusting the structural parameters could significantly improve the advantage of the sandwich shell.Then,the hydrostatic pressure tests for shell models fabricated by 3D printing are carried out.According to the experimental results,the overall failure position of the sandwich shell is at the center part of the sandwich shell.It has been found the average critical load of the proposed sandwich shell models exceeds two times that of the unstiffened shell models.Hence,the proposed bio-inspired bidirectional corrugated sandwich structure can significantly enhance the pressure resistance capability of cylindrical shells.
基金supported by the National Natural Science Foundation of China(52177217)。
文摘Typical application scenarios,such as vehicle to grid(V2G)and frequency regulation,have imposed significant long-life demands on lithium-ion batteries.Herein,we propose an advanced battery life-extension method employing bidirectional pulse charging(BPC)strategy.Unlike traditional constant current charging methods,BPC strategy not only achieves comparable charging speeds but also facilitates V2G frequency regulation simultaneously.It significantly enhances battery cycle ampere-hour throughput and demonstrates remarkable life extension capabilities.For this interesting conclusion,adopting model identification and postmortem characterization to reveal the life regulation mechanism of BPC:it mitigates battery capacity loss attributed to loss of lithium-ion inventory(LLI)in graphite anodes by intermittently regulating the overall battery voltage and anode potential using a negative charging current.Then,from the perspective of internal side reaction,the life extension mechanism is further revealed as inhibition of solid electrolyte interphase(SEI)and lithium dendrite growth by regulating voltage with a bidirectional pulse current,and a semi-empirical life degradation model combining SEI and lithium dendrite growth is developed for BPC scenarios health management,the model parameters are identified by genetic algorithm with the life simulation exhibiting an accuracy exceeding 99%.This finding indicates that under typical rate conditions,adaptable BPC strategies can extend the service life of LFP battery by approximately 123%.Consequently,the developed advanced BPC strategy offers innovative perspectives and insights for the development of long-life battery applications in the future.
文摘Objective To investigate the causal relationships between plasma metabolites and osteoporosis via Mendelian randomization(MR) analysis.Methods Bidirectional MR was used to analyze pooled data from different genome-wide association studies(GWAS). The causal effect of plasma metabolites on osteoporosis was estimated using the inverse variance weighted method, intersections of statistically significant metabolites obtained from different sources of osteoporosis-related GWAS aggregated data was determined, and then sensitivity analysis was performed on these metabolites. Heterogeneity between single nucleotide polymorphisms was evaluated by Cochran's Q test. Horizontal pleiotropy was assessed through the application of the MR-Egger intercept method and the MRPRESSO method. The causal effect of osteoporosis on plasma metabolites was also evaluated using the inverse variance weighted method. Additionally, pathway analysis was conducted to identify potential metabolic pathways involved in the regulation of osteoporosis.Results Primary analysis and sensitivity analysis showed that 77 and 61 plasma metabolites had a causal relationship with osteoporosis from the GWAS data in the GCST90038656 and GCST90044600 datasets, respectively. Five common metabolites were identified via intersection. X-13684 levels and the glucose-to-maltose ratio were negatively associated with osteoporosis, whereas glycoursodeoxycholate levels and arachidoylcarnitine(C20) levels were positively associated with osteoporosis(all P < 0.05). The relationship between X-11299 levels and osteoporosis showed contradictory results(all P < 0.05). Pathway analysis indicated that glycine, serine, and threonine metabolism, valine, leucine, and isoleucine biosynthesis, galactose metabolism, arginine biosynthesis, and starch and sucrose metabolism pathways were participated in the development of osteoporosis.Conclusion We found a causal relationship between plasma metabolites and osteoporosis. These results offer novel perspectives with important implications for targeted metabolite-focused interventions in the management of osteoporosis.
基金This work was supported by the Humanities and Social Science Fund of Ministry of Education of China(No.20YJA630009)Shandong Natural Science Foundation of China(No.ZR2022MG002).
文摘This study delves into the formation dynamics of alliances within a closed-loop supply chain(CLSC)that encom-passes a manufacturer,a retailer,and an e-commerce platform.It leverages Stackelberg game for this exploration,contrasting the equilibrium outcomes of a non-alliance model with those of three differentiated alliance models.The non-alliance model acts as a crucial benchmark,enabling the evaluation of the motivations for various supply chain entities to engage in alliance formations.Our analysis is centered on identifying the most effective alliance strategies and establishing a coordination within these partnerships.We thoroughly investigate the consequences of diverse alliance behaviors,bidirectional free-riding and cost-sharing,and the resultant effects on the optimal decision-making among supply chain actors.The findings underscore several pivotal insights:(1)The behavior of alliances within the supply chain exerts variable impacts on the optimal pricing and demand of its members.In comparison to the non-alliance(D)model,the manufacturer-retailer(MR)and manufacturer-e-commerce platform(ME)alliances significantly lower both offline and online resale prices for new and remanufactured goods.This adjustment leads to an enhanced demand for products via the MR alliance’s offline outlets and the ME alliance’s online platforms,thereby augmenting the profits for those within the alliance.Conversely,retailer-e-commerce platform(ER)alliance tends to increase the optimal retail price and demand across both online and offline channels.Under specific conditions,alliance behavior can also increase the profits of non-alliance members,and the profits derived through alliance channels also exceed those from non-alliance channels.(2)The prevalence of bidirectional free-riding behavior largely remains constant across different alliance configurations.Across these models,bidirectional free-riding typically elevates the equilibrium prices in offline channel while negatively affecting the equilibrium prices in other channel.(3)The effect of cost-sharing shows relative uniformity across the various alliance models.Across all configurations,cost-sharing tends to reduce the manufacturer’s profits.Nonetheless,alliances initiated by the manufacturer can counteract these negative impacts,providing a strategic pathway to bolster CLSC profitability.
基金the National Natural Science Foundation of China(No.52275062)and(No.52075262).
文摘Since backlash nonlinearity is inevitably existing in actuators for bidirectional stabilization system of allelectric tank,it behaves more drastically in high maneuvering environments.In this work,the accurate tracking control for bidirectional stabilization system of moving all-electric tank with actuator backlash and unmodeled disturbance is solved.By utilizing the smooth adaptive backlash inverse model,a nonlinear robust adaptive feedback control scheme is presented.The unknown parameters and unmodelled disturbance are addressed separately through the derived parametric adaptive function and the continuous nonlinear robust term.Because the unknown backlash parameters are updated via adaptive function and the backlash effect can be suppressed successfully by inverse operation,which ensures the system stability.Meanwhile,the system disturbance in the high maneuverable environment can be estimated with the constructed adaptive law online improving the engineering practicality.Finally,Lyapunov-based analysis proves that the developed controller can ensure the tracking error asymptotically converges to zero even with unmodeled disturbance and unknown actuator backlash.Contrast co-simulations and experiments illustrate the advantages of the proposed approach.
文摘Diabetes mellitus and depression exhibit a complex bidirectional relationship that profoundly impacts patient health and quality of life.This review explores the physiological mechanisms,including inflammation,oxidative stress,and neu-roendocrine dysregulation,that link these conditions.Psychosocial factors such as social support and lifestyle choices also contribute significantly.Epidemiological insights reveal a higher prevalence of depression among diabetics and an in-creased risk of diabetes in depressed individuals,influenced by demographic variables.Integrated management strategies combining mental health asse-ssments and personalized treatments are essential.Future research should focus on longitudinal and multi-omics studies to deepen understanding and improve therapeutic outcomes.
基金Deanship of Research and Graduate Studies at King Khalid University for funding this work through Small Group Research Project under Grant Number RGP1/261/45.
文摘Breast cancer is a significant threat to the global population,affecting not only women but also a threat to the entire population.With recent advancements in digital pathology,Eosin and hematoxylin images provide enhanced clarity in examiningmicroscopic features of breast tissues based on their staining properties.Early cancer detection facilitates the quickening of the therapeutic process,thereby increasing survival rates.The analysis made by medical professionals,especially pathologists,is time-consuming and challenging,and there arises a need for automated breast cancer detection systems.The upcoming artificial intelligence platforms,especially deep learning models,play an important role in image diagnosis and prediction.Initially,the histopathology biopsy images are taken from standard data sources.Further,the gathered images are given as input to the Multi-Scale Dilated Vision Transformer,where the essential features are acquired.Subsequently,the features are subjected to the Bidirectional Long Short-Term Memory(Bi-LSTM)for classifying the breast cancer disorder.The efficacy of the model is evaluated using divergent metrics.When compared with other methods,the proposed work reveals that it offers impressive results for detection.
基金This work was supported by the National Natural Science Foundation of China(61704054,92161115,62374099,and 62022047)the Fundamental Research Funds for the Central Universities(JB2020MS042 and JB2019MS051).
文摘Two-dimensional(2D)WSe_(2)has received increasing attention due to its unique optical properties and bipolar behavior.Several WSe_(2)-based heterojunctions exhibit bidirectional rectification characteristics,but most devices have a lower rectification ratio.In this work,the Bi_(2)O_(2)Se/WSe_(2)heterojunction prepared by us has a typeⅡband alignment,which can vastly suppress the channel current through the interface barrier so that the Bi_(2)O_(2)Se/WSe_(2)heterojunction device has a large rectification ratio of about 10^(5).Meanwhile,under different gate voltage modulation,the current on/off ratio of the device changes by nearly five orders of magnitude,and the maximum current on/off ratio is expected to be achieved 106.The photocurrent measurement reveals the behavior of recombination and space charge confinement,further verifying the bidirectional rectification behavior of heterojunctions,and it also exhibits excellent performance in light response.In the future,Bi_(2)O_(2)Se/WSe_(2)heterojunction field-effect transistors have great potential to reduce the volume of integrated circuits as a bidirectional controlled switching device.
基金This work was supported in part by the National Key R&D Program of China 2021YFE0110500in part by the National Natural Science Foundation of China under Grant 62062021in part by the Guiyang Scientific Plan Project[2023]48-11.
文摘Unsupervised methods based on density representation have shown their abilities in anomaly detection,but detection performance still needs to be improved.Specifically,approaches using normalizing flows can accurately evaluate sample distributions,mapping normal features to the normal distribution and anomalous features outside it.Consequently,this paper proposes a Normalizing Flow-based Bidirectional Mapping Residual Network(NF-BMR).It utilizes pre-trained Convolutional Neural Networks(CNN)and normalizing flows to construct discriminative source and target domain feature spaces.Additionally,to better learn feature information in both domain spaces,we propose the Bidirectional Mapping Residual Network(BMR),which maps sample features to these two spaces for anomaly detection.The two detection spaces effectively complement each other’s deficiencies and provide a comprehensive feature evaluation from two perspectives,which leads to the improvement of detection performance.Comparative experimental results on the MVTec AD and DAGM datasets against the Bidirectional Pre-trained Feature Mapping Network(B-PFM)and other state-of-the-art methods demonstrate that the proposed approach achieves superior performance.On the MVTec AD dataset,NF-BMR achieves an average AUROC of 98.7%for all 15 categories.Especially,it achieves 100%optimal detection performance in five categories.On the DAGM dataset,the average AUROC across ten categories is 98.7%,which is very close to supervised methods.
文摘The rate equation model is setup for the signal gain, pump absorption and output noise spectrum of bidirectional EDFA (Bi EDFA) including numbers of signals, pumps of arbitrary direction, amplified spontaneous emission (ASE) and inherent loss. The influence of erbium doped fiber length, input signal power, pump style and pump power on the gain characteristics of Bi EDFA is analyzed. Forward and backward noise figure for different pump style versus bidirectional input signal power is investigated.
基金The National Natural Science Foundation of China(No.5117810151378112)the Doctoral Fund of Ministry of Education(No.20110092110011)
文摘To study the seismic performance of double-skin steelconcrete composite box( DSCB) piers, a total of 11 DSCB pier specimens were tested under bidirectional cyclic loading. The effects of the loading pattern, the steel plate thickness, the axial load ratio, the slenderness ratio and the aspect ratio were taken into consideration. The damage evolution process and failure modes of the tested specimens are presented in detail. Test results are also discussed in terms of the hysteretic curve, skeleton curve, ductility and energy dissipation capacity of DSCB pier specimens. It can be concluded that the hysteretic performance of DSCB piers in one direction is affected and weakened by the cyclic loading in the other direction. DSCB piers under bidirectional cyclic loading exhibit good performance in terms of load carrying capacity, ductility, and energy dissipation capacity. Overall, DSCB piers can meet the basic aseismic requirements. The research results can be taken as a reference for using DSCB piers as high piers in bridges in strong earthquakeprone areas.
文摘The multiple classifier system (MCS), composed of multiple diverse classifiers or feed-forward neural networks, can significantly improve the classification or generalization ability of a single classifier. Enlightened by the fundamental idea of MCS, the ensemble is introduced into the quick learning for bidirectional associative memory (QLBAM) to construct a BAM ensemble, for improving the storage capacity and the error-correction capability without destroying the simple structure of the component BAM. Simulations show that, with an appropriate "overproduce and choose" strategy or "thinning" algorithm, the proposed BAM ensemble significantly outperforms the single QLBAM in both storage capacity and noise-tolerance capability.
文摘In this paper we propose a new discrete bidirectional associative memory (DBAM) which is derived from our previous continuous linear bidirectional associative memory (LBAM). The DBAM performs bidirectionally the optimal associative mapping proposed by Kohonen. Like LBAM and NBAM proposed by one of the present authors,the present BAM ensures the guaranteed recall of all stored patterns,and possesses far higher capacity compared with other existing BAMs,and like NBAM, has the strong ability to suppress the noise occurring in the output patterns and therefore reduce largely the spurious patterns. The derivation of DBAM is given and the stability of DBAM is proved. We also derive a learning algorithm for DBAM,which has iterative form and make the network learn new patterns easily. Compared with NBAM the present BAM can be easily implemented by software.
文摘This paper reports on an investigation of the seismic response of base-isolated reinforced concrete buildings, which considers various isolation system parameters under bidirectional near-fault and far-fault motions. Three-dimensional models of 4-, 8-, and 12-story base-isolated buildings with nonlinear effects in the isolation system and the superstructure are investigated, and nonlinear response history analysis is carried out. The bounding values of isolation system properties that incorporate the aging effect of isolators are also taken into account, as is the current state of practice in the design and analysis of base-isolated buildings. The response indicators of the buildings are studied for near-fault and far-fault motions weight-scaled to represent the design earthquake (DE) level and the risk-targeted maximum considered earthquake (MCER) level. Results of the nonlinear response history analyses indicate no structural damage under DE-level motions for near-fault and far-fault motions and for MCER-level far-fault motions, whereas minor structural damage is observed under MCER- level near-fault motions. Results of the base-isolated buildings are compared with their fixed-base counterparts. Significant reduction of the superstructure response of the 12-story base-isolated building compared to the fixed-base condition indicates that base isolation can be effectively used in taller buildings to enhance performance. Additionally, the applicability of a rigid superstructure to predict the isolator displacement demand is also investigated. It is found that the isolator displacements can be estimated accurately using a rigid body model for the superstructure for the buildings considered.
基金Supported by the National Natural Science Funda-tion of China (60403027)
文摘In traditional networks , the authentication is performed by certificate authoritys(CA),which can't be built in distributed mobile Ad Hoc Networks however. In this pa per, we propose a fully self-organized public key management based on bidirectional trust model without any centralized authority that allows users to generate their public-private key pairs, to issue certificates, and the trust relation spreads rationally according to the truly human relations. In contrast with the traditional self-organized public-key management, the average certificates paths get more short, the authentication passing rate gets more high and the most important is that the bidirectional trust based model satisfys the trust re quirement of hosts better.
文摘In this study,dynamic responses of two buildings connected by viscoelastic dampers under bidirectional excitations are extensively investigated.The two buildings are a 10-story building and a 16-story building,with the shorter building on the left.Viscoelastic dampers are installed at all fl oors of the shorter building.Equations of motion are formulated using a fractional derivative model to represent the viscoelastic dampers.Three cases are considered with mass eccentricities at 0,10% and-10% with respect to the dimensions of the buildings.The responses of the buildings are numerically predicted at different damper properties.The simulation results indicated that the maximum horizontal responses of the buildings without eccentricities are signifi cantly mitigated.However,torsional effects are adversely increased.For asymmetric buildings,the effectiveness of the connecting dampers is affected by building eccentricities.As a result,mass eccentricities must be taken into account in damper selection.When compared with vibrations induced by unidirectional excitations,bidirectional excitations can increase the responses of coupled asymmetric buildings.In addition,installing dampers only at the top fl oor of the shorter building may cause a sudden change in lateral stiffness of the taller building.Consequently,the story shear envelopes of the taller building are changed.
文摘Bidirectional Dijkstra algorithm whose time complexity is 8O(n~2) is proposed. The theory foundation is that the classical Dijkstra algorithm has not any directional feature during searching the shortest path. The algorithm takes advantage of the adjacent link and the mechanism of bidirectional search, that is, the algorithm processes the positive search from start point to destination point and the negative search from destination point to start point at the same time. Finally, combining with the practical application of route-planning algorithm in embedded real-time vehicle navigation system (ERTVNS), one example of its practical applications is given, analysis in theory and the experimental results show that compared with the Dijkstra algorithm, the new algorithm can reduce time complexity, and guarantee the searching precision, it satisfies the needs of ERTVNS.
基金supported by the National Natural Science Foundation of China,No.81371312,81030021the National Basic Research Development Program of China(973 Program),No.2011CB504403
文摘Multiple cellular components, including neuronal, glial and endothelial ceils, are involved in the sophis- ticated pathological processes following central nervous system injury. The pathological process cannot reduce damage or improve functional recovery by merely targeting the molecular mechanisms of neuronal cell death after central nerve system injuries. Eph receptors and ephrin ligands have drawn wide attention since the discovery of their extensive distribution and unique bidirectional signaling between astrocytes and neurons. The roles of Eph/ephrin bidirectional signaling in the developmental processes have been re- ported in previous research. Recent observations suggest that Eph/ephrin bidirectional signaling continues to be expressed in most regions and cell types in the adult central nervous system, playing diverse roles. The Eph/ephrin complex mediates neurogenesis and angiogenesis, promotes glial scar formation, regulates endocrine levels, inhibits myelin formation and aggravates inflammation and nerve pain caused by injury. ~lhe interaction between Eph and ephrin is also considered to be the key to angiogenesis. This review focus- es on the roles of Eph/ephrin bidirectional signaling in the repair of central nervous system injuries.
文摘Modelling of bidirectional full bridge DC-DC converter as one of the most applicable converters has received significant attention. Mathematical modelling reduces the simulation time in comparison with detailed circuit response;moreover it is convenient for controller design purpose. Due to simple and effective methodology, average state space is the most common method among the modelling methods. In this paper a bidirectional full bridge converter is modelled by average state space and for each mode of operations a controller is designed. Attained mathematical model results are in a close agreement with detailed circuit simulation.
文摘An effective approach is presented to extract welds from real-time radiographs, Firstly an algorithm based on an adaptive bidirectional threshold was proposed to segment the gradient image into ternary image, and then the bidirectional accumulator Hough Transform was developed to extract weld edges from the ternary image. Different values of the coefficient proposed in the threshold algorithm were tested, and the proposed approach was applied to extract welds from real-time radiographic images of different types of welds with defects. Results show that the proposed method is adaptive and effective to extract welds from real-time radiographs of linear welds.