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The Influence of Saturated and Bilinear Incidence Functions on the Dynamical Behavior of HIV Model Using Galerkin Scheme Having a Polynomial of Order Two
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作者 Attaullah Kamil Zeb Abdullah Mohamed 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第8期1661-1685,共25页
Mathematical modelling has been extensively used to measure intervention strategies for the control of contagious conditions.Alignment between different models is pivotal for furnishing strong substantiation for polic... Mathematical modelling has been extensively used to measure intervention strategies for the control of contagious conditions.Alignment between different models is pivotal for furnishing strong substantiation for policymakers because the differences in model features can impact their prognostications.Mathematical modelling has been widely used in order to better understand the transmission,treatment,and prevention of infectious diseases.Herein,we study the dynamics of a human immunodeficiency virus(HIV)infection model with four variables:S(t),I(t),C(t),and A(t)the susceptible individuals;HIV infected individuals(with no clinical symptoms of AIDS);HIV infected individuals(under ART with a viral load remaining low),and HIV infected individuals with two different incidence functions(bilinear and saturated incidence functions).A novel numerical scheme called the continuous Galerkin-Petrov method is implemented for the solution of themodel.The influence of different clinical parameters on the dynamical behavior of S(t),I(t),C(t)and A(t)is described and analyzed.All the results are depicted graphically.On the other hand,we explore the time-dependent movement of nanofluid in porous media on an extending sheet under the influence of thermal radiation,heat flux,hall impact,variable heat source,and nanomaterial.The flow is considered to be 2D,boundary layer,viscous,incompressible,laminar,and unsteady.Sufficient transformations turn governing connected PDEs intoODEs,which are solved using the proposed scheme.To justify the envisaged problem,a comparison of the current work with previous literature is presented. 展开更多
关键词 HIV/AIDS Galerkin technique bilinear and saturated incidence functions
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THE DYNAMICS AND THERAPEUTIC STRATEGIES OF A SEIS EPIDEMIC MODEL
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作者 XINZHU MENG ZHITAO WU TONGQIAN ZHANG 《International Journal of Biomathematics》 2013年第5期41-58,共18页
Based on an epidemic model which Manvendra and Vinay [Mathematical model to simulate infections disease, VSRD-TNTJ 3(2) (2012) 60 68] have proposed, we consider the dynamics and therapeutic strategy of a SEIS epid... Based on an epidemic model which Manvendra and Vinay [Mathematical model to simulate infections disease, VSRD-TNTJ 3(2) (2012) 60 68] have proposed, we consider the dynamics and therapeutic strategy of a SEIS epidemic model with latent patients and active patients. First, the basic reproduction number is established by applying the method of the next generation matrix. By means of appropriate Lyapunov functions, it is proven that while the basic reproduction number 0 〈 R0 〈 1, the disease-free equilibrium is globally asymptotically stable and the disease eliminates; and if the basic reproduction number R0 〉 1, the endemic equilibrium is globally asymptotically stable and therefore the disease becomes endemic. Numerical investigations of their basin of attraction indicate that the locally stable equilibria are global attractors. Second, we consider the impact of treatment on epidemic disease and analytically determine the most effective therapeutic strategy. We conclude that the most effective therapeutic strategy consists of treating both the exposed and the infectious, while treating only the exposed is the least effective therapeutic strategy. Finally, numerical simulations are given to illustrate the effectiveness of the proposed results. 展开更多
关键词 Endemic disease bilinear incidence local stability global stability treatmentstrategies.
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