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Expression of insulin-like growth factor Ⅱ and its receptor in hepatocellular carcinogenesis 被引量:24
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作者 Zi Rong Fan Dong Hua Yang +2 位作者 Jun Cui Han Rong Qin Chun Chi Huang Department of Gastroenterology, Zhujiang Hospital. The First Military Medical University, Guangzhou 510282.Guangdong Province. China 《World Journal of Gastroenterology》 SCIE CAS CSCD 2001年第2期285-288,共4页
INTRODUCTIONInsulin-like growth factor Ⅱ(IGF-Ⅱ) is a mitogenic peptide of 74 kD and is mostly synthesized in fetal liver tissue .IGF-Ⅱ is believed to play an important role in fetal growth and development and is in... INTRODUCTIONInsulin-like growth factor Ⅱ(IGF-Ⅱ) is a mitogenic peptide of 74 kD and is mostly synthesized in fetal liver tissue .IGF-Ⅱ is believed to play an important role in fetal growth and development and is involved in cellular proliferation and differentiation[1-5]. Recently ,several researchers have reported increased expression of the IGF-Ⅱgene in human hepatocellular carcinoma (HCC) and adjacent non-cancerous liver tissues [6-10]. 展开更多
关键词 liver neoplasms/pathology insulin-like growth factor Ⅱ/biosynthesis receptors somatomedin/biosynthesis RNA messenger/biosynthesis in situ hybridization hepatitis chronic/pathology
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