Background: Oral health has been implicated in low birth weight or preterm birth. However, this relationship has not yet been studied in twins. We investigated whether maternal oral health was associated with the birt...Background: Oral health has been implicated in low birth weight or preterm birth. However, this relationship has not yet been studied in twins. We investigated whether maternal oral health was associated with the birth weights of twins by a cross-sectional study conducted at Helsinki University Central Hospital. Methods: Utilizing linear mixed effect models to recognize the correlation between twins from the same mothers and the independence between different mothers. 40 birth weights of twins were modeled as main outcomes. In model 1, poor periodontal health (PPH) was fitted as the main explanatory variable. In model 2, presence of non-specific oral mucositis (NSOM) was fitted as the main predictor. Results: In model 1, babies from mothers with PPH weighed approximately 158.2 grams less than babies of mothers without PPH. However, this association was not statistically significant (p = 0.11). When a stricter criterion for PPH (3 sites of pocket depth > 4 mm) was used, p-value decreased to 0.09 showing a dose response to PPH. In model 2, mothers with NSOM had babies weighing 224.9 grams less than mothers without these lesions. This was nearly significant (p = 0.08). Conclusion: Although not significant, the results from this small data of twins suggest that maternal oral health may be associated with birth weight of twin neonates. Our results are appropriate to generate hypothesis for future studies.展开更多
目的基于家庭支持的中介效应探讨妊娠期糖尿病(GDM)自我管理能力与新生儿出生体质量、Apgar评分的关系。方法选取许昌市中心医院2022年4月至2023年4月收治的92例GDM患者,采用GDM专用自我管理能力量表评价其自我管理能力,利用糖尿病专用...目的基于家庭支持的中介效应探讨妊娠期糖尿病(GDM)自我管理能力与新生儿出生体质量、Apgar评分的关系。方法选取许昌市中心医院2022年4月至2023年4月收治的92例GDM患者,采用GDM专用自我管理能力量表评价其自我管理能力,利用糖尿病专用家庭支持问卷评价其家庭支持情况,且均随访统计新生儿出生体质量、出生1 min Apgar评分。Pearson法分析自我管理能力与家庭支持、新生儿出生体质量、Apgar评分及家庭支持与新生儿出生体质量、Apgar评分的相关性;Mplus8.3软件分析家庭支持在GDM自我管理能力与新生儿出生体质量、Apgar评分间的中介效应,并经Bootstrap法验证。结果患者自我管理能力评分(72.08±13.03)分,家庭支持总分(20.33±4.21),新生儿出生体质量(3308.10±1005.31)g,Apgar评分(8.23±1.69)分;患者自我管理能力总分与家庭支持总分、Apgar评分均呈正相关,差异有统计学意义(P<0.05),与新生儿出生体质量呈负相关,差异有统计学意义(P<0.05);患者家庭支持总分与新生儿出生体质量呈负相关,差异有统计学意义(P<0.05),与Apgar评分呈正相关,差异有统计学意义(P<0.05);患者自我管理能力可影响新生儿出生体质量、Apgar评分,差异均有统计学意义(P<0.05),患者自我管理能力可影响家庭支持,差异有统计学意义(P<0.05),家庭支持在患者自我管理能力与新生儿出生体质量、Apgar评分间呈部分中介效应,差异有统计学意义(P<0.05);自我管理能力对新生儿出生体质量、Apgar评分的直接效应为0.65、0.68,家庭支持对新生儿出生体质量、Apgar评分的间接效应为0.24、0.22,总效应为0.89、0.90。结论GDM自我管理能力待提升、家庭支持水平低,且二者均与新生儿出生体质量、Apgar评分有关,家庭支持在自我管理能力与新生儿出生体质量、Apgar评分间起中介效应。展开更多
文摘Background: Oral health has been implicated in low birth weight or preterm birth. However, this relationship has not yet been studied in twins. We investigated whether maternal oral health was associated with the birth weights of twins by a cross-sectional study conducted at Helsinki University Central Hospital. Methods: Utilizing linear mixed effect models to recognize the correlation between twins from the same mothers and the independence between different mothers. 40 birth weights of twins were modeled as main outcomes. In model 1, poor periodontal health (PPH) was fitted as the main explanatory variable. In model 2, presence of non-specific oral mucositis (NSOM) was fitted as the main predictor. Results: In model 1, babies from mothers with PPH weighed approximately 158.2 grams less than babies of mothers without PPH. However, this association was not statistically significant (p = 0.11). When a stricter criterion for PPH (3 sites of pocket depth > 4 mm) was used, p-value decreased to 0.09 showing a dose response to PPH. In model 2, mothers with NSOM had babies weighing 224.9 grams less than mothers without these lesions. This was nearly significant (p = 0.08). Conclusion: Although not significant, the results from this small data of twins suggest that maternal oral health may be associated with birth weight of twin neonates. Our results are appropriate to generate hypothesis for future studies.
文摘目的基于家庭支持的中介效应探讨妊娠期糖尿病(GDM)自我管理能力与新生儿出生体质量、Apgar评分的关系。方法选取许昌市中心医院2022年4月至2023年4月收治的92例GDM患者,采用GDM专用自我管理能力量表评价其自我管理能力,利用糖尿病专用家庭支持问卷评价其家庭支持情况,且均随访统计新生儿出生体质量、出生1 min Apgar评分。Pearson法分析自我管理能力与家庭支持、新生儿出生体质量、Apgar评分及家庭支持与新生儿出生体质量、Apgar评分的相关性;Mplus8.3软件分析家庭支持在GDM自我管理能力与新生儿出生体质量、Apgar评分间的中介效应,并经Bootstrap法验证。结果患者自我管理能力评分(72.08±13.03)分,家庭支持总分(20.33±4.21),新生儿出生体质量(3308.10±1005.31)g,Apgar评分(8.23±1.69)分;患者自我管理能力总分与家庭支持总分、Apgar评分均呈正相关,差异有统计学意义(P<0.05),与新生儿出生体质量呈负相关,差异有统计学意义(P<0.05);患者家庭支持总分与新生儿出生体质量呈负相关,差异有统计学意义(P<0.05),与Apgar评分呈正相关,差异有统计学意义(P<0.05);患者自我管理能力可影响新生儿出生体质量、Apgar评分,差异均有统计学意义(P<0.05),患者自我管理能力可影响家庭支持,差异有统计学意义(P<0.05),家庭支持在患者自我管理能力与新生儿出生体质量、Apgar评分间呈部分中介效应,差异有统计学意义(P<0.05);自我管理能力对新生儿出生体质量、Apgar评分的直接效应为0.65、0.68,家庭支持对新生儿出生体质量、Apgar评分的间接效应为0.24、0.22,总效应为0.89、0.90。结论GDM自我管理能力待提升、家庭支持水平低,且二者均与新生儿出生体质量、Apgar评分有关,家庭支持在自我管理能力与新生儿出生体质量、Apgar评分间起中介效应。
