Effect of black and white sesame on lowering blood lipids of rats with hyperlipidemia induced by high-fat diet

Sesamum indicum has various biological effects,and this study aimed to investigate its hypolipidemic effect.A hyperlipidemia rat model was established by feeding rats with high-fat diets in this study,then the hyperlipidemia rats were fed with different doses of black and white sesame seeds and black and white sesame kernels.The serum and liver biochemical indicators of the rats were determined,and liver pathology analysis was conducted to evaluate the hypolipidemic effect of sesame.The results showed that the blood lipid of SD(Sprague-Dawley)rats fed with high-fat diet for three weeks was higher than 200 mg/d L,indicating that the hyperlipidemia rat model was successfully established.At the same dose,the final body weights of the rats of white sesame seed and kernel groups were higher than those of the black sesame seed and kernel groups;and the weights of the black and white sesame seed groups were lower than those of the black and white sesame kernel groups.The liver indexes of the normal control group and the experimental groups were significantly lower than the model control group(P<0.05),indicating that black and white sesame seed and kernel could reduce the lipid accumulation on the liver.The malondialdehyde(MDA)values of the liver in the normal control group and the experimental groups were significantly lower than that in the model control group(P<0.05).The total antioxidant capacity(T-AOC),high density lipoprotein cholesterol(HDL-C),glutathione peroxidase(GSH-Px)and total superoxide dismutase(T-SOD)in the liver of each experimental group were significantly higher than those in the model control group(P<0.05).Based on the above results as well as pathological observation and analysis,we found that the black and white sesame seeds and kernels could improve fatty liver lesions and lipid metabolism disorder and could reduce lipid accumulation on the liver,thereby protecting the liver from damage and reducing the risk of fatty liver.Moreover,black and white sesame seeds,black and white sesame kernels can reduce the levels of total cholesterol(TC)and triglyceride(TG)in serum,and high dose of black sesame seeds(30%black sesame seeds)and low dose of black sesame kernels(10%black sesame kernels)were more beneficial for the recovery of hyperlipidemia and fatty liver.The above results indicated that black and white sesame has hypolipidemic effect.

BLACK AND WHITE

IN 1958,the renowned dancing master B.Gusev,directed thefirst complete balletic drama in China——Swan Lake.It symbolizedthe birth of the art of ballet in a country with over 5,000 yearsworth of civilization.By succeeding in the traditions of Westernclassical ballet,China has made great straits on the nationalizationof this art form.In 1986,he China Central Ballet Troupe(CCBT)

Ether as the Fundamental Substance of the Creation of the Universe

The paper analyzes the concept of Ether and substantiates the necessity of its existence as a physical reality, which arises within the framework of the concept developed by the authors of the work. The authors come to the conclusion that the existence of Ether in two different forms, plays an exceptional role in the formation of Dark Matter and Dark Energy and leads to the emergence of exotic cosmological structures and their hierarchy in energy, temporal, and spatial scale. The mechanism of the formation of physical structures before the Big Bang and their further evolution, up to the formation of worlds of galaxies and stars, is considered. The necessity of the emergence of exotic structures, such as 3 spheres of the Primary Relict, is shown, its structure and dynamic properties leading to the formation of Order from Chaos are considered. The role of the 1st and 2nd type Ether in the formation of the mechanism of transformation of cosmic energies and quantum phase transitions, in the process of the birth and evolution of the Universe is discussed. The conclusion is made about the existence of universal properties of matter, at the level of Macro and Microcosms, and a multidimensional cosmological model with an isothermal temperature distribution is constructed, leading to a discrete distribution of matter separated by transitions, by analogy with Black-and-White Holes. It is shown that the postulate of the constancy of the speed of light in any inertial system is a consequence of the principle of covariance.

The Dark Side of the Screen—A Resistance to Changing Times

This essay argues that black and white cinema spawned a resistance to changing times that is still very present in the new generation of directors who follow classic film traditions while subverting them with consistent narrative inventions.The Artist,the best picture Oscar award winner in 2012,is an example of this resistance as it pays homage to some of the greatest silent films of the first two or three decades of cinema history.“The Dark Side of the Screen”aims to underline that there is an unchanging power of the phantasmagoria so present in black and white movies,produced not only in the silent era but also in film noir through lighting effects and camera angles which characterize the work of major noir directors like Fritz Lang,Billy Wilder,and Orson Welles,who knew everything about the unutterable mysteries hidden on the dark side of the screen.

Implicit Heaviside filter with high continuity based on suitably graded THB splines

The variable density topology optimization(TO)method has been applied to various engineering fields because it can effectively and efficiently generate the conceptual design for engineering structures.However,it suffers from the problem of low continuity resulting from the discreteness of both design variables and explicit Heaviside filter.In this paper,an implicit Heaviside filter with high continuity is introduced to generate black and white designs for TO where the design space is parameterized by suitably graded truncated hierarchical B-splines(THB).In this approach,the fixed analysis mesh of isogeometric analysis is decoupled from the design mesh,whose adaptivity is implemented by truncated hierarchical B-spline subjected to an admissible requirement.Through the intrinsic local support and high continuity of THB basis,an implicit adaptively adjusted Heaviside filter is obtained to remove the checkboard patterns and generate black and white designs.Threefold advantages are attained in the proposed filter:a)The connection between analysis mesh and adaptive design mesh is easily established compared with the traditional adaptive TO method using nodal density;b)the efficiency in updating design variables is remarkably improved than the traditional implicit sensitivity filter based on B-splines under successive global refinement;and c)the generated black and white designs are preliminarily compatible with current commercial computer aided design system.Several numerical examples are used to verify the effectiveness of the proposed implicit Heaviside filter in compliance and compliant mechanism as well as heat conduction TO problems.