Background： About 50% of the cerebral ischemia events are induced by intracranial and extracranial atheroscterosis. This study aimed to evaluate the feasibility and accuracy for displaying atherosclerotic plaques in ...Background： About 50% of the cerebral ischemia events are induced by intracranial and extracranial atheroscterosis. This study aimed to evaluate the feasibility and accuracy for displaying atherosclerotic plaques in carotid arteries and analyzing their ingredients by using high-resolution new magnetic resonance imaging （MRI） techniques. Methods： Totally, 49 patients suspected ofextracranial carotid artery stenosis were subjected to cranial MRI scan and magnetic resonance angiography （MRA） examination on carotid arteries, and high-resolution bright-blood and black-blood MRI analysis was carried out within 1 week. Digital subtraction angiography （DSA） examination was carried out for 16 patients within I month. Results： Totally, 103 plaques were detected in the 49 patients, which were characterized by localized or diffusive thickening of the vessel wall, with the intrusion of crescent-shaped abnormal signal into lumens. Fibrous cap was displayed as isointensity in T I -weighted image （T I WI） and hyperintensities in proton density weighted image （PDWI） and T2-weighted image （T2WI）, lipid core was displayed as isointensity or slight hyperintensities in T1WI, isointensity, hyperintensities or hypointensity in PDWI, and hypointensity in T2WI. Calcification in plaques was detected in 11 patients. Eight patients were detected with irregular plaque surface or ulcerative plaques, which were characterized by irregular intravascular space surface in the black-blood sequences, black hypointensity band was not detected in three-dimensional time-of-flight, or the hypointensity band was not continuous, and intrusion of hyperintensities into plaques can be detected. Bright-blood and black-blood techniques were highly correlated with the diagnosis of contrast-enhanced MRA in angiostenosis degree, Rs 0.97, P 〈 0.001. In comparison to DSA, the sensitivity, specificity, and accuracy of MRI diagnosis of stenosis for ≥50% were 88.9%. 100%, and 97.9%, respectively. Conclusions： High-resolution bright-blood and black-blood sequential MRI analysis can accurately analyze ingredients in atherosclerotic plaques, Determined by DSA, MRI diagnosis of stenosis can correctly evaluate the serious degree of arteriostenosis.展开更多
目的:探讨3.0T磁共振流动敏感黑血序列三维T_(1)加权增强扫描(FSBB 3D CE-T_(1)WI)在脑转移瘤中的应用价值。方法:回顾性将2021年1月-2022年8月在本院就诊且经临床和影像检查证实的52例脑转移患者纳入研究。所有患者分别行颅脑FSBB 3D C...目的:探讨3.0T磁共振流动敏感黑血序列三维T_(1)加权增强扫描(FSBB 3D CE-T_(1)WI)在脑转移瘤中的应用价值。方法:回顾性将2021年1月-2022年8月在本院就诊且经临床和影像检查证实的52例脑转移患者纳入研究。所有患者分别行颅脑FSBB 3D CE-T_(1)WI、FSE CE-T_(1)WI和快速梯度回波序列三维T_(1)加权对比增强(FFE 3D CE-T_(1)WI)扫描,采用卡方检验或Fisher精确概率检验比较3个序列之间病灶检出率的差异。结果:经随访证实颅内转移灶总数为371个,FSBB 3D CE-T_(1)WI的检出率99.73%(370/371),FFE 3D CE-T_(1)WI的检出率为83.02%(308/371),FSE CE-T_(1)WI的检出率为78.44%(291/371),三者之间检出率的差异有统计学意义(χ^(2)=82.748,P<0.05)。分层分析:直径<3 mm的转移灶共160个,FSE CE-T_(1)WI、FFE 3D CE-T_(1)WI和FSBB 3D CE-T_(1)WI的检出率分别为50.62%、60.62%和99.37%,三个序列之间检出率的差异有统计学意义(χ^(2)=101.436,P<0.05);对于直径3~10 mm的转移灶,FSE CE-T_(1)WI、FFE 3D CE-T_(1)WI和FSBB 3D CE-T_(1)WI的检出率分别为99.38%、100%和100%,三个序列之间检出率的差异无统计学意义(P>0.05);对直径>10 mm的转移灶,三个序列的检出率均为100%,差异无统计学意义(P>0.05)。结论:FSBB 3D CE-T_(1)WI在检出脑转移瘤方面要优于常规和高分辨序列MR增强扫描,值得临床推广。展开更多
目的探讨分别采用相位排序自动门控窗选择(PAWS)及同时多重容积(SMV)算法双呼吸导航门控与屏气二维双反转恢复快速自旋回波(2DNAV DIR FSE,2DBH DIR FSE)黑血心脏MR序列的图像质量,评价前者的临床应用可行性及价值。方法对15名健康成年...目的探讨分别采用相位排序自动门控窗选择(PAWS)及同时多重容积(SMV)算法双呼吸导航门控与屏气二维双反转恢复快速自旋回波(2DNAV DIR FSE,2DBH DIR FSE)黑血心脏MR序列的图像质量,评价前者的临床应用可行性及价值。方法对15名健康成年志愿者分别进行2DNAV DIR FSE及2DBH DIR FSE黑血MR心脏成像,对比评价两个序列对应层面的图像质量(定性评价及定量分析)。结果 2名医师评估2DNAV DIR FSE序列图像质量的一致性较好(Kappa=0.573,P<0.01);2名医师对2DNAV DIR FSE序列相对诊断可信性主观评分显著相关(r=0.733,P<0.01)。2DNAV DIR FSE序列各层面图像左心室心肌、心腔信噪比及左心室心肌/心腔对比噪声比均低于2DBH DIRFSE序列(t=-15.847、-18.399、-14.824,P均<0.05)。结论采用PAWS及SMV算法的2DNAV DIR FSE黑血MR序列对于屏气配合差的患者优势明显,但对屏气配合良好者不宜作为首选。展开更多
文摘Background： About 50% of the cerebral ischemia events are induced by intracranial and extracranial atheroscterosis. This study aimed to evaluate the feasibility and accuracy for displaying atherosclerotic plaques in carotid arteries and analyzing their ingredients by using high-resolution new magnetic resonance imaging （MRI） techniques. Methods： Totally, 49 patients suspected ofextracranial carotid artery stenosis were subjected to cranial MRI scan and magnetic resonance angiography （MRA） examination on carotid arteries, and high-resolution bright-blood and black-blood MRI analysis was carried out within 1 week. Digital subtraction angiography （DSA） examination was carried out for 16 patients within I month. Results： Totally, 103 plaques were detected in the 49 patients, which were characterized by localized or diffusive thickening of the vessel wall, with the intrusion of crescent-shaped abnormal signal into lumens. Fibrous cap was displayed as isointensity in T I -weighted image （T I WI） and hyperintensities in proton density weighted image （PDWI） and T2-weighted image （T2WI）, lipid core was displayed as isointensity or slight hyperintensities in T1WI, isointensity, hyperintensities or hypointensity in PDWI, and hypointensity in T2WI. Calcification in plaques was detected in 11 patients. Eight patients were detected with irregular plaque surface or ulcerative plaques, which were characterized by irregular intravascular space surface in the black-blood sequences, black hypointensity band was not detected in three-dimensional time-of-flight, or the hypointensity band was not continuous, and intrusion of hyperintensities into plaques can be detected. Bright-blood and black-blood techniques were highly correlated with the diagnosis of contrast-enhanced MRA in angiostenosis degree, Rs 0.97, P 〈 0.001. In comparison to DSA, the sensitivity, specificity, and accuracy of MRI diagnosis of stenosis for ≥50% were 88.9%. 100%, and 97.9%, respectively. Conclusions： High-resolution bright-blood and black-blood sequential MRI analysis can accurately analyze ingredients in atherosclerotic plaques, Determined by DSA, MRI diagnosis of stenosis can correctly evaluate the serious degree of arteriostenosis.
文摘目的:探讨3.0T磁共振流动敏感黑血序列三维T_(1)加权增强扫描(FSBB 3D CE-T_(1)WI)在脑转移瘤中的应用价值。方法:回顾性将2021年1月-2022年8月在本院就诊且经临床和影像检查证实的52例脑转移患者纳入研究。所有患者分别行颅脑FSBB 3D CE-T_(1)WI、FSE CE-T_(1)WI和快速梯度回波序列三维T_(1)加权对比增强(FFE 3D CE-T_(1)WI)扫描,采用卡方检验或Fisher精确概率检验比较3个序列之间病灶检出率的差异。结果:经随访证实颅内转移灶总数为371个,FSBB 3D CE-T_(1)WI的检出率99.73%(370/371),FFE 3D CE-T_(1)WI的检出率为83.02%(308/371),FSE CE-T_(1)WI的检出率为78.44%(291/371),三者之间检出率的差异有统计学意义(χ^(2)=82.748,P<0.05)。分层分析:直径<3 mm的转移灶共160个,FSE CE-T_(1)WI、FFE 3D CE-T_(1)WI和FSBB 3D CE-T_(1)WI的检出率分别为50.62%、60.62%和99.37%,三个序列之间检出率的差异有统计学意义(χ^(2)=101.436,P<0.05);对于直径3~10 mm的转移灶,FSE CE-T_(1)WI、FFE 3D CE-T_(1)WI和FSBB 3D CE-T_(1)WI的检出率分别为99.38%、100%和100%,三个序列之间检出率的差异无统计学意义(P>0.05);对直径>10 mm的转移灶,三个序列的检出率均为100%,差异无统计学意义(P>0.05)。结论:FSBB 3D CE-T_(1)WI在检出脑转移瘤方面要优于常规和高分辨序列MR增强扫描,值得临床推广。
文摘目的探讨分别采用相位排序自动门控窗选择(PAWS)及同时多重容积(SMV)算法双呼吸导航门控与屏气二维双反转恢复快速自旋回波(2DNAV DIR FSE,2DBH DIR FSE)黑血心脏MR序列的图像质量,评价前者的临床应用可行性及价值。方法对15名健康成年志愿者分别进行2DNAV DIR FSE及2DBH DIR FSE黑血MR心脏成像,对比评价两个序列对应层面的图像质量(定性评价及定量分析)。结果 2名医师评估2DNAV DIR FSE序列图像质量的一致性较好(Kappa=0.573,P<0.01);2名医师对2DNAV DIR FSE序列相对诊断可信性主观评分显著相关(r=0.733,P<0.01)。2DNAV DIR FSE序列各层面图像左心室心肌、心腔信噪比及左心室心肌/心腔对比噪声比均低于2DBH DIRFSE序列(t=-15.847、-18.399、-14.824,P均<0.05)。结论采用PAWS及SMV算法的2DNAV DIR FSE黑血MR序列对于屏气配合差的患者优势明显,但对屏气配合良好者不宜作为首选。
