This paper investigated the existence of splitting balanced incomplete block designs with blck size 2× k .The necessary conditions for such a design are λ(v-1) ≡0(mod k ),and λv(v- 1)≡0(mod 2 k 2).It will sho...This paper investigated the existence of splitting balanced incomplete block designs with blck size 2× k .The necessary conditions for such a design are λ(v-1) ≡0(mod k ),and λv(v- 1)≡0(mod 2 k 2).It will show that the above necessary conditions are also sufficient for k =3 with the definite exception( v,λ )=(10,1) and with several possible exceptions.展开更多
The necessary conditions for the existence of weak designs are given in the form of two inequalities in this paper. The relations among weak block designs (WBDs) , Balanced incomplete block designs ( BIBDs) and differ...The necessary conditions for the existence of weak designs are given in the form of two inequalities in this paper. The relations among weak block designs (WBDs) , Balanced incomplete block designs ( BIBDs) and differential balanced block designs (DBBDs) are researched.展开更多
General solution of normal equations in the general intra-block analysis of partially balanced incomplete block designs involving four associates is presented in this talk as they are quite useful in practice. Only in...General solution of normal equations in the general intra-block analysis of partially balanced incomplete block designs involving four associates is presented in this talk as they are quite useful in practice. Only intra-block estimates are given as the necessary formulae for inter-block estimates can be derived from them by changing the parameters as discussed in Rao[5]. We have obtained the general formulae for computation of four types of efficiencies, the average efficiency factor and the variance of the estimated elementary treatment contrast of the four types of comparisons irrespective of the type of association scheme a PBIB Design follows.展开更多
By taking as blocks certain subspace-pairs of an orthogonal geometry over a finite field with characteristic≠2 we construct some new types of BIB designs and PBIB designs whose parameters are also given.
The necessary and sufficient conditions for the existence of simple incomplete block design (v, ω; 4, 2)-IPBDs are determined. As a consequence, the necessary and sufficient conditions for the embeddings of simple ...The necessary and sufficient conditions for the existence of simple incomplete block design (v, ω; 4, 2)-IPBDs are determined. As a consequence, the necessary and sufficient conditions for the embeddings of simple two-fold balanced incomplete block designs with block size 4 are also determined.展开更多
In the experimental field, researchers need very often to select the best subset model as well as reach the best model estimation simultaneously. Selecting the best subset of variables will improve the prediction accu...In the experimental field, researchers need very often to select the best subset model as well as reach the best model estimation simultaneously. Selecting the best subset of variables will improve the prediction accuracy as noninformative variables will be removed. Having a model with high prediction accuracy allows the researchers to use the model for future forecasting. In this paper, we investigate the differences between various variable selection methods. The aim is to compare the analysis of the frequentist methodology (the backward elimination), penalised shrinkage method (the Adaptive LASSO) and the Least Angle Regression (LARS) for selecting the active variables for data produced by the blocked design experiment. The result of the comparative study supports the utilization of the LARS method for statistical analysis of data from blocked experiments.展开更多
This paper studies the nonsystematic Low-Density Parity-Check(LDPC)codes based onSymmetric Balanced Incomplete Block Design(SBIBD).First,it is concluded that the performancedegradation of nonsystematic linear block co...This paper studies the nonsystematic Low-Density Parity-Check(LDPC)codes based onSymmetric Balanced Incomplete Block Design(SBIBD).First,it is concluded that the performancedegradation of nonsystematic linear block codes is bounded by the average row weight of generalizedinverses of their generator matrices and code rate.Then a class of nonsystematic LDPC codes con-structed based on SBIBD is presented.Their characteristics include:both generator matrices andparity-check matrices are sparse and cyclic,which are simple to encode and decode;and almost arbi-trary rate codes can be easily constructed,so they are rate-compatible codes.Because there aresparse generalized inverses of generator matrices,the performance of the proposed codes is only0.15dB away from that of the traditional systematic LDPC codes.展开更多
A collection of k-matchings of bipartite graph Kn,n with the property thatevery pair of independent edges lies in exactly λ of the k-matchings is called aBIMATCH(n,k,λ)-design. Existences and constructions for vario...A collection of k-matchings of bipartite graph Kn,n with the property thatevery pair of independent edges lies in exactly λ of the k-matchings is called aBIMATCH(n,k,λ)-design. Existences and constructions for various BIMATCH (n,k,λ)designs are given.展开更多
Methods of constructing the optimum chemical balance weighing designs from symmetric balanced incomplete block designs are proposed with illustration. As a by-product pairwise efficiency and variance balanced designs ...Methods of constructing the optimum chemical balance weighing designs from symmetric balanced incomplete block designs are proposed with illustration. As a by-product pairwise efficiency and variance balanced designs are also obtained.展开更多
A new set of binary sequences-Periodic Complementary Binary Sequence Pair (PCSP) is proposed. A new class of block design-Difference Family Pair (DFP) is also proposed.The relationship between PCSP and DFP, the proper...A new set of binary sequences-Periodic Complementary Binary Sequence Pair (PCSP) is proposed. A new class of block design-Difference Family Pair (DFP) is also proposed.The relationship between PCSP and DFP, the properties and existing conditions of PCSP and the recursive constructions for PCSP are given.展开更多
Facial synkinesis,a sequela of peripheral facial nerve palsy,is characterized by simultaneous involuntary facial movement during a voluntary desired one.Maladaptive cortical plasticity might be involved in the dysfunc...Facial synkinesis,a sequela of peripheral facial nerve palsy,is characterized by simultaneous involuntary facial movement during a voluntary desired one.Maladaptive cortical plasticity might be involved in the dysfunction of facial muscles.This cohort study investigated the cortical functional alterations in patients with unilateral facial synkinesis,using the task functional magnetic resonance imaging.Facial motor tasks,including blinking and smiling,were performed by 16 patients(aged 30.6 ± 4.5 years,14 females/2 males) and 24 age-and sex-matched healthy controls(aged 29.1 ± 4.2 years,19 females/5 males).Results demonstrated that activation in the cortico-facial motor representation area was lower during tasks in patients with facial synkinesis compared with healthy controls.Facial movements on either side performed by patients caused more intensive activation of the supplementary motor area on the contralateral side of the affected face,than those on the unaffected side.Our results revealed that there was cortical reorganization in the primary sensorimotor area and the supplementary motor area.This study was registered in Chinese Clinical Trial Registry(registration number: Chi CTR1800014630).展开更多
In this work,an optimal Q algorithm based on a collision recovery scheme is presented. Tags use BIBD-( 16,4,1) codes instead of RN16 s. Therefore,readers can make a valid recognition even in collision slots. A way of ...In this work,an optimal Q algorithm based on a collision recovery scheme is presented. Tags use BIBD-( 16,4,1) codes instead of RN16 s. Therefore,readers can make a valid recognition even in collision slots. A way of getting the optimal slot-count parameter is studied and an optimal Q algorithm is proposed. The theoretical and simulation results show that the proposed algorithm can improve reading efficiency by 100% more than the conventional Q algorithm. Moreover,the proposed scheme changes little to the existing standard. Thus,it is easy to implement and compatible with ISO 18000-6C.展开更多
This article is a contribution to the study of block-transitive automorphism groups of 2-(v,k,1) block designs. Let D be a 2-(v,k,1) design admitting a block-transitive, pointprimitive but not flag-transitive auto...This article is a contribution to the study of block-transitive automorphism groups of 2-(v,k,1) block designs. Let D be a 2-(v,k,1) design admitting a block-transitive, pointprimitive but not flag-transitive automorphism group G. Let kr = (k,v-1) and q = pf for prime p. In this paper we prove that if G and D are as above and q (3(krk-kr + 1)f)1/3, then G does not admit a simple group E6(q) as its socle.展开更多
When running an experiment, inhomogeneity of the experimental units may result in poor estimations of treatment effects. Thus, it is desirable to select a good blocked design before running the experiment. Mostly, a s...When running an experiment, inhomogeneity of the experimental units may result in poor estimations of treatment effects. Thus, it is desirable to select a good blocked design before running the experiment. Mostly, a single block variable was used in the literature to treat the inhomogeneity for simplicity. However, in practice, the inhomogeneity often comes from multi block variables. Recently, a new criterion called B2-GMC was proposed for two-level regular designs with multi block variables. This paper proposes a systematic theory on constructing some B^2-GMC designs for the first time. Experimenters can easily obtain the B^2-GMC designs according to the construction method. Pros of B^2-GMC designs are highlighted in Section 4, and the designs with small run sizes are tabulated in Appendix B for practical use.展开更多
Although some patients have successful peripheral nerve regeneration,a poor recovery of hand function often occurs after peripheral nerve injury.It is believed that the capability of brain plasticity is crucial for th...Although some patients have successful peripheral nerve regeneration,a poor recovery of hand function often occurs after peripheral nerve injury.It is believed that the capability of brain plasticity is crucial for the recovery of hand function.The supplementary motor area may play a key role in brain remodeling after peripheral nerve injury.In this study,we explored the activation mode of the supplementary motor area during a motor imagery task.We investigated the plasticity of the central nervous system after brachial plexus injury,using the motor imagery task.Results from functional magnetic resonance imaging showed that after brachial plexus injury,the motor imagery task for the affected limbs of the patients triggered no obvious activation of bilateral supplementary motor areas.This result indicates that it is difficult to excite the supplementary motor areas of brachial plexus injury patients during a motor imagery task,thereby impacting brain remodeling.Deactivation of the supplementary motor area is likely to be a serious problem for brachial plexus injury patients in terms of preparing,initiating and executing certain movements,which may be partly responsible for the unsatisfactory clinical recovery of hand function.展开更多
Chinese Remainder Codes are constructed by applying weak block designs and Chinese Remainder Theorem of ring theory. The new type of linear codes take the congruence class in the congruence class ring R/I 1∩I 2∩.....Chinese Remainder Codes are constructed by applying weak block designs and Chinese Remainder Theorem of ring theory. The new type of linear codes take the congruence class in the congruence class ring R/I 1∩I 2∩...∩I n for the information bit, embed R/J i into R/I 1∩I 2∩...∩I n, and asssign the cosets of R/J i as the subring of R/I 1∩I 2∩...∩I n and the cosets of R/J i in R/I 1∩I 2∩...∩I n as check lines. There exist many code classes in Chinese Remainder Codes, which have high code rates. Chinese Remainder Codes are the essential generalization of Sun Zi Codes.展开更多
In many experiments, the performance of a subject may be affected by some previous treatments applied to it apart from the current treatment. This motivates the studies of the residual effects of the treatments in a b...In many experiments, the performance of a subject may be affected by some previous treatments applied to it apart from the current treatment. This motivates the studies of the residual effects of the treatments in a block design. This paper shows that a circular block design neighbor-balanced at distances up toγ≤k - 1, where k is the block size, is universally optimal for total effects under the linear models containing the neighbor effects at distances up toγamong the class of all circular binary block designs. Some combinatorial approaches to constructing these circular block designs neighbor-balanced at distances up to k - 1 are provided.展开更多
Given any positive integers k3 and λ,let c(k,λ)denote the smallest integer such that u ∈ B(k,λ)for every integer uc(k,λ)that satisfies the congruences λv(v-1)≡0(mod k(k-1))and λ(u-1)≡0(mod k-1...Given any positive integers k3 and λ,let c(k,λ)denote the smallest integer such that u ∈ B(k,λ)for every integer uc(k,λ)that satisfies the congruences λv(v-1)≡0(mod k(k-1))and λ(u-1)≡0(mod k-1).In this article we make an improvement on the bound of c(k,λ)provided by Chang in[4]and prove that c(k,λ)exp{k<sup>3k<sup>6</sup></sup>}.In particular,c(k,1)exp{k<sup>k<sup>2</sup></sup>}.展开更多
Let (v, u × c,λ)-splitting BIBD denote a (v, u × c,λ)-splitting balanced incomplete block design of order v with block size u × c and index A. The necessary conditions for the existence of a (v, ...Let (v, u × c,λ)-splitting BIBD denote a (v, u × c,λ)-splitting balanced incomplete block design of order v with block size u × c and index A. The necessary conditions for the existence of a (v, u × c,λ)-splitting BIBD are v ≥ uc, λ(v- 1) -- 0 0 mod (c(u- 1)) and Av(v- 1) - 0 mod (c^2u(u- 1)). In this paper, for 2 ≤λ≤ 9 the necessary conditions for the existence of a (v, 3 × 3, λ)-splitting BIBD are also sufficient with one possible exception for (v, λ) = (39, 9).展开更多
The conventional approach to investigating functional connectivity in the block-designed study usually concatenates task blocks or employs residuals of task activation.While providing many insights into brain function...The conventional approach to investigating functional connectivity in the block-designed study usually concatenates task blocks or employs residuals of task activation.While providing many insights into brain functions,the block design adds more manipulation in functional network analysis that may reduce the purity of the blood oxygenation level-dependent signal.Recent studies utilized one single long run for task trials of the same condition,the so-called continuous design,to investigate functional connectivity based on task functional magnetic resonance imaging.Continuous brain activities associated with the single-task condition can be directly utilized for task-related functional connectivity assessment,which has been examined for working memory,sensory,motor,and semantic task experiments in previous research.But it remains unclear how the block and continuous design influence the assessment of task-related functional connectivity networks.This study aimed to disentangle the separable effects of block/continuous design and working memory load on task-related functional connectivity networks,by using repeated-measures analysis of variance.Across 50 young healthy adults,behavioral results of accuracy and reaction time showed a significant main effect of design as well as interaction between design and load.Imaging results revealed that the cingulo-opercular,fronto-parietal,and default model networks were associated with not only task activation,but significant main effects of design and load as well as their interaction on intra-and inter-network functional connectivity and global network topology.Moreover,a significant behavior-brain association was identified for the continuous design.This work has extended the evidence that continuous design can be used to study task-related functional connectivity and subtle brain-behavioral relationships.展开更多
基金National Natural Science Foundation ofChina(No.10 4710 93)
文摘This paper investigated the existence of splitting balanced incomplete block designs with blck size 2× k .The necessary conditions for such a design are λ(v-1) ≡0(mod k ),and λv(v- 1)≡0(mod 2 k 2).It will show that the above necessary conditions are also sufficient for k =3 with the definite exception( v,λ )=(10,1) and with several possible exceptions.
文摘The necessary conditions for the existence of weak designs are given in the form of two inequalities in this paper. The relations among weak block designs (WBDs) , Balanced incomplete block designs ( BIBDs) and differential balanced block designs (DBBDs) are researched.
文摘General solution of normal equations in the general intra-block analysis of partially balanced incomplete block designs involving four associates is presented in this talk as they are quite useful in practice. Only intra-block estimates are given as the necessary formulae for inter-block estimates can be derived from them by changing the parameters as discussed in Rao[5]. We have obtained the general formulae for computation of four types of efficiencies, the average efficiency factor and the variance of the estimated elementary treatment contrast of the four types of comparisons irrespective of the type of association scheme a PBIB Design follows.
文摘By taking as blocks certain subspace-pairs of an orthogonal geometry over a finite field with characteristic≠2 we construct some new types of BIB designs and PBIB designs whose parameters are also given.
基金Project supported by the National Natural Science Foundation of China (No. 10471093).
文摘The necessary and sufficient conditions for the existence of simple incomplete block design (v, ω; 4, 2)-IPBDs are determined. As a consequence, the necessary and sufficient conditions for the embeddings of simple two-fold balanced incomplete block designs with block size 4 are also determined.
文摘In the experimental field, researchers need very often to select the best subset model as well as reach the best model estimation simultaneously. Selecting the best subset of variables will improve the prediction accuracy as noninformative variables will be removed. Having a model with high prediction accuracy allows the researchers to use the model for future forecasting. In this paper, we investigate the differences between various variable selection methods. The aim is to compare the analysis of the frequentist methodology (the backward elimination), penalised shrinkage method (the Adaptive LASSO) and the Least Angle Regression (LARS) for selecting the active variables for data produced by the blocked design experiment. The result of the comparative study supports the utilization of the LARS method for statistical analysis of data from blocked experiments.
基金the National Natural Science Foundation of China(No.60272009,No.60472045,and No.60496313).
文摘This paper studies the nonsystematic Low-Density Parity-Check(LDPC)codes based onSymmetric Balanced Incomplete Block Design(SBIBD).First,it is concluded that the performancedegradation of nonsystematic linear block codes is bounded by the average row weight of generalizedinverses of their generator matrices and code rate.Then a class of nonsystematic LDPC codes con-structed based on SBIBD is presented.Their characteristics include:both generator matrices andparity-check matrices are sparse and cyclic,which are simple to encode and decode;and almost arbi-trary rate codes can be easily constructed,so they are rate-compatible codes.Because there aresparse generalized inverses of generator matrices,the performance of the proposed codes is only0.15dB away from that of the traditional systematic LDPC codes.
文摘A collection of k-matchings of bipartite graph Kn,n with the property thatevery pair of independent edges lies in exactly λ of the k-matchings is called aBIMATCH(n,k,λ)-design. Existences and constructions for various BIMATCH (n,k,λ)designs are given.
文摘Methods of constructing the optimum chemical balance weighing designs from symmetric balanced incomplete block designs are proposed with illustration. As a by-product pairwise efficiency and variance balanced designs are also obtained.
基金Supported by National Natural Science Foundation of China (69972042),Natural Science Fund of Hebei Provice(599245)and Science Foundation of Yanshan University
文摘A new set of binary sequences-Periodic Complementary Binary Sequence Pair (PCSP) is proposed. A new class of block design-Difference Family Pair (DFP) is also proposed.The relationship between PCSP and DFP, the properties and existing conditions of PCSP and the recursive constructions for PCSP are given.
基金supported by the Youth Researcher Foundation of Shanghai Municipal Commission of Health and Family Planning,No.20144Y0095
文摘Facial synkinesis,a sequela of peripheral facial nerve palsy,is characterized by simultaneous involuntary facial movement during a voluntary desired one.Maladaptive cortical plasticity might be involved in the dysfunction of facial muscles.This cohort study investigated the cortical functional alterations in patients with unilateral facial synkinesis,using the task functional magnetic resonance imaging.Facial motor tasks,including blinking and smiling,were performed by 16 patients(aged 30.6 ± 4.5 years,14 females/2 males) and 24 age-and sex-matched healthy controls(aged 29.1 ± 4.2 years,19 females/5 males).Results demonstrated that activation in the cortico-facial motor representation area was lower during tasks in patients with facial synkinesis compared with healthy controls.Facial movements on either side performed by patients caused more intensive activation of the supplementary motor area on the contralateral side of the affected face,than those on the unaffected side.Our results revealed that there was cortical reorganization in the primary sensorimotor area and the supplementary motor area.This study was registered in Chinese Clinical Trial Registry(registration number: Chi CTR1800014630).
基金Supported by the National Natural Science Foundation of China(No.61340005)Beijing Natural Science Foundation(No.4132012)+2 种基金Beijing Education Committee Science and Technology Development Plan(No.KM201411232011)Beijing Outstanding Personnel Training Project(No.2013D005007000006)Scientific Research Improving Project-Intelligent Sense and Information Processing(No.5211524100)
文摘In this work,an optimal Q algorithm based on a collision recovery scheme is presented. Tags use BIBD-( 16,4,1) codes instead of RN16 s. Therefore,readers can make a valid recognition even in collision slots. A way of getting the optimal slot-count parameter is studied and an optimal Q algorithm is proposed. The theoretical and simulation results show that the proposed algorithm can improve reading efficiency by 100% more than the conventional Q algorithm. Moreover,the proposed scheme changes little to the existing standard. Thus,it is easy to implement and compatible with ISO 18000-6C.
基金Supported by the National Natural Science Foundation of China (Grant No.10871205)China Postdoctoral Science Foundation Funded Project (Grant No.20080441323) Scientific Research Fund of Zhejiang Education Department (Grant No.Y200804780)
文摘This article is a contribution to the study of block-transitive automorphism groups of 2-(v,k,1) block designs. Let D be a 2-(v,k,1) design admitting a block-transitive, pointprimitive but not flag-transitive automorphism group G. Let kr = (k,v-1) and q = pf for prime p. In this paper we prove that if G and D are as above and q (3(krk-kr + 1)f)1/3, then G does not admit a simple group E6(q) as its socle.
基金supported by the National Natural Science Foundation of China under Grant Nos.11271205,11371223,11431006 and 11601244the Specialized Research Fund for the Doctoral Program of Higher Education of China under Grant No.20130031110002+1 种基金the“131”Talents Program of Tianjinthe Program for Scientific Research Innovation Team in Applied Probability and Statistics of Qufu Normal University under Grant No.0230518
文摘When running an experiment, inhomogeneity of the experimental units may result in poor estimations of treatment effects. Thus, it is desirable to select a good blocked design before running the experiment. Mostly, a single block variable was used in the literature to treat the inhomogeneity for simplicity. However, in practice, the inhomogeneity often comes from multi block variables. Recently, a new criterion called B2-GMC was proposed for two-level regular designs with multi block variables. This paper proposes a systematic theory on constructing some B^2-GMC designs for the first time. Experimenters can easily obtain the B^2-GMC designs according to the construction method. Pros of B^2-GMC designs are highlighted in Section 4, and the designs with small run sizes are tabulated in Appendix B for practical use.
基金supported by the Youth Researcher Foundation of Shanghai Health Development Planning Commission,No.20124319
文摘Although some patients have successful peripheral nerve regeneration,a poor recovery of hand function often occurs after peripheral nerve injury.It is believed that the capability of brain plasticity is crucial for the recovery of hand function.The supplementary motor area may play a key role in brain remodeling after peripheral nerve injury.In this study,we explored the activation mode of the supplementary motor area during a motor imagery task.We investigated the plasticity of the central nervous system after brachial plexus injury,using the motor imagery task.Results from functional magnetic resonance imaging showed that after brachial plexus injury,the motor imagery task for the affected limbs of the patients triggered no obvious activation of bilateral supplementary motor areas.This result indicates that it is difficult to excite the supplementary motor areas of brachial plexus injury patients during a motor imagery task,thereby impacting brain remodeling.Deactivation of the supplementary motor area is likely to be a serious problem for brachial plexus injury patients in terms of preparing,initiating and executing certain movements,which may be partly responsible for the unsatisfactory clinical recovery of hand function.
文摘Chinese Remainder Codes are constructed by applying weak block designs and Chinese Remainder Theorem of ring theory. The new type of linear codes take the congruence class in the congruence class ring R/I 1∩I 2∩...∩I n for the information bit, embed R/J i into R/I 1∩I 2∩...∩I n, and asssign the cosets of R/J i as the subring of R/I 1∩I 2∩...∩I n and the cosets of R/J i in R/I 1∩I 2∩...∩I n as check lines. There exist many code classes in Chinese Remainder Codes, which have high code rates. Chinese Remainder Codes are the essential generalization of Sun Zi Codes.
基金This work was partially supported by the National Natural Science Foundation of China (Grant Nos. 10671007,10471127)Zhejiang Provincial Natural Science Foundation of China (Grant No. R604001)the Scientific Research Foundation for the Returned Overseas Chinese Scholars, Ministry of Education of China and a CERG grant from Research Grants Council of Hong Kong
文摘In many experiments, the performance of a subject may be affected by some previous treatments applied to it apart from the current treatment. This motivates the studies of the residual effects of the treatments in a block design. This paper shows that a circular block design neighbor-balanced at distances up toγ≤k - 1, where k is the block size, is universally optimal for total effects under the linear models containing the neighbor effects at distances up toγamong the class of all circular binary block designs. Some combinatorial approaches to constructing these circular block designs neighbor-balanced at distances up to k - 1 are provided.
基金Supported by NSFC Grant No.19701002 and Huo Yingdong Foundation
文摘Given any positive integers k3 and λ,let c(k,λ)denote the smallest integer such that u ∈ B(k,λ)for every integer uc(k,λ)that satisfies the congruences λv(v-1)≡0(mod k(k-1))and λ(u-1)≡0(mod k-1).In this article we make an improvement on the bound of c(k,λ)provided by Chang in[4]and prove that c(k,λ)exp{k<sup>3k<sup>6</sup></sup>}.In particular,c(k,1)exp{k<sup>k<sup>2</sup></sup>}.
基金the National Natural Science Foundation of China (No. 10771193)the Starter Foundation for the Doctors of Zhejiang Gongshang University(No. 1020XJ030517)+1 种基金the Natural Science Foundationof Universities of Jiangsu Province (No. 07KJB110090)the Starter Foundation for the Doctors of Nantong University (No. 07B12)
文摘Let (v, u × c,λ)-splitting BIBD denote a (v, u × c,λ)-splitting balanced incomplete block design of order v with block size u × c and index A. The necessary conditions for the existence of a (v, u × c,λ)-splitting BIBD are v ≥ uc, λ(v- 1) -- 0 0 mod (c(u- 1)) and Av(v- 1) - 0 mod (c^2u(u- 1)). In this paper, for 2 ≤λ≤ 9 the necessary conditions for the existence of a (v, 3 × 3, λ)-splitting BIBD are also sufficient with one possible exception for (v, λ) = (39, 9).
基金supported by the National Natural Science Foundation of China(62071109 and 61871420)the Provincial Natural Science Foundation of Sichuan(2022NSFSC0504).
文摘The conventional approach to investigating functional connectivity in the block-designed study usually concatenates task blocks or employs residuals of task activation.While providing many insights into brain functions,the block design adds more manipulation in functional network analysis that may reduce the purity of the blood oxygenation level-dependent signal.Recent studies utilized one single long run for task trials of the same condition,the so-called continuous design,to investigate functional connectivity based on task functional magnetic resonance imaging.Continuous brain activities associated with the single-task condition can be directly utilized for task-related functional connectivity assessment,which has been examined for working memory,sensory,motor,and semantic task experiments in previous research.But it remains unclear how the block and continuous design influence the assessment of task-related functional connectivity networks.This study aimed to disentangle the separable effects of block/continuous design and working memory load on task-related functional connectivity networks,by using repeated-measures analysis of variance.Across 50 young healthy adults,behavioral results of accuracy and reaction time showed a significant main effect of design as well as interaction between design and load.Imaging results revealed that the cingulo-opercular,fronto-parietal,and default model networks were associated with not only task activation,but significant main effects of design and load as well as their interaction on intra-and inter-network functional connectivity and global network topology.Moreover,a significant behavior-brain association was identified for the continuous design.This work has extended the evidence that continuous design can be used to study task-related functional connectivity and subtle brain-behavioral relationships.