Premixed insulin combines two types of insulin in a single injection.This combination streamlines dosing for patients with type 1 or type 2 diabetes,thereby enhancing convenience.However,patients receiving premixed in...Premixed insulin combines two types of insulin in a single injection.This combination streamlines dosing for patients with type 1 or type 2 diabetes,thereby enhancing convenience.However,patients receiving premixed insulin commonly have less satisfactory blood glucose control.The fixed ratio of insulin in these formulations frequently fails to account for the nuanced demands of individualized glucose-lowering therapy.Moreover,local absorption of mixed insulin and potential systemic autoimmune responses may further compromise glycaemic control.The co-formulation of insulin degludec and insulin aspart introduces a new combination of the two insulin types within a single injection,offering a promising solution for mitigating the limitations inherent in premixed insulin.展开更多
文摘Premixed insulin combines two types of insulin in a single injection.This combination streamlines dosing for patients with type 1 or type 2 diabetes,thereby enhancing convenience.However,patients receiving premixed insulin commonly have less satisfactory blood glucose control.The fixed ratio of insulin in these formulations frequently fails to account for the nuanced demands of individualized glucose-lowering therapy.Moreover,local absorption of mixed insulin and potential systemic autoimmune responses may further compromise glycaemic control.The co-formulation of insulin degludec and insulin aspart introduces a new combination of the two insulin types within a single injection,offering a promising solution for mitigating the limitations inherent in premixed insulin.
