AIM： To investigate the incidence of various types of postoperative pulmonary complications （POPCs） and to evaluate the significance of perioperative arterial blood gases in patients with esophageal cancer accompan...AIM： To investigate the incidence of various types of postoperative pulmonary complications （POPCs） and to evaluate the significance of perioperative arterial blood gases in patients with esophageal cancer accompanied with chronic obstructive pulmonary disease （COPD） after esophagectomy. MEHTODS： Three hundred and fifty-eight patients were divided into POPC group and COPD group. We performed a retrospective review of the 358 consecutive patients after esophagectomy for esophageal cancer with or without COPD to assess the possible influence of COPD on postoperative pulmonary complications. We classified COPD into four grades according to percent-predicted forced expiratory volume in 1 s （FEV1） and analyzed the incidence rate of complications among the four grades. Perioperative arterial blood gases were tested in patients with or without pulmonary complications in COPD group and compared with POP（： group. RESULTS： Patients with COPD （29/86, 33.7%）had more pulmonary complications than those without COPD （36/272, 13.2%） （P〈0.001）. Pneumonia （15/29, 51.7%）, atelectasis （13/29, 44.8%）, prolonged 02 supplement （10/29, 34.5%）, and prolonged mechanical ventilation （8/29, 27.6%） were the major complications in COPD group. Moreover, patients with severe COPD （grade Ⅱ B, FEV1 〈 50% of predicted） had more POPCs than those with moderate（gradeⅡA,50%-80% of predicted） and mild （grade Ⅰ≥80% of predicted） COPD （P〈0.05）. PaO2 was decreased and PaCO2 was increased in patients with pulmonary complications in COPD group in the first postoperative week.CONCLUSION： The criteria of COPD are the critical predictor for pulmonary complications in esophageal cancer patients undergoing esophagectomy. Severity of COPD affects the incidence rate of the pulmonary complication,and percent-predicted FEV1 is a good predictive variable for pulmonary complication in patients-with COPD.Arterial blood gases are helpful in directing perioperative management.展开更多
目的分析慢性阻塞性肺疾病急性加重期(acute exacerbation phase of chronic obstructive pulmonary disease,AECOPD)炎症介质与肺功能的相关性。方法选取2021年6月—2023年6月泰州市姜堰中医院收治的110例AECOPD患者为加重组,另外选取7...目的分析慢性阻塞性肺疾病急性加重期(acute exacerbation phase of chronic obstructive pulmonary disease,AECOPD)炎症介质与肺功能的相关性。方法选取2021年6月—2023年6月泰州市姜堰中医院收治的110例AECOPD患者为加重组,另外选取71例COPD患者作为稳定组,选取同期健康体检者67例作为对照组。观察3组患者一般资料、检测患者炎症介质、肺功能指标。分析不同肺功能分级患者炎症介质、肺功能指标水平,并分析炎症介质与肺功能的相关性。结果与对照组相比,稳定组、加重组患者舒张压、收缩压、血肌酐、空腹血糖、白细胞(white blood cell,WBC)、降钙素原(procalcitonin,PCT)、超敏C反应蛋白(hypersensitive c reactive protein,hs-CRP)、白介素-6(interleukin-6,IL-6)、血清淀粉样蛋白A(serum amyloid A,SAA)表达水平逐渐升高,第1秒用力呼气容量/用力肺活量比值(forced expiratory volume in the first second/forced vital capacity,FEV1/FVC)、第1秒用力呼气容量(forced expiratory volume in the first second,FEV1)表达水平逐渐降低(P<0.05)。与Ⅰ级相比,Ⅱ级、Ⅲ级患者PCT、hs-CRP、IL-6、SAA表达水平逐渐升高,FEV1/FVC、FEV1水平逐渐降低(P<0.05)。相关性分析显示,FEV1/FVC、FEV1水平与PCT、hs-CRP、IL-6、SAA呈负相关(P<0.05)。多因素logistic回归分析显示,舒张压、收缩压、血肌酐、空腹血糖、WBC水平为AECOPD的主要危险因素(P<0.05)。结论AECOPD患者肺功能与炎症介质相关,检测患者炎症介质、肺功能状态,可用于患者病情的评估。展开更多
<em>Diabetes </em>is a chronic illness that occurs when the pancreas stops producing insulin or when the body cannot use the produced insulin. <em>Insulin</em> is a hormone produced by the panc...<em>Diabetes </em>is a chronic illness that occurs when the pancreas stops producing insulin or when the body cannot use the produced insulin. <em>Insulin</em> is a hormone produced by the pancreas that helps glucose from meals enters the body’s cells for energy. The overall goal is to assess diabetes patients’ knowledge, attitudes, and behaviors about prevalent diabetic complications. This research used a descriptive qualitative methodology to assess diabetes complication knowledge, attitude, and practice. Ninety-eight diabetic patients were visiting the Egyptian Hospital in Mogadishu for four weeks. The data was collected using questionnaires. Finally, SPSS 20 was utilized for analysis. The research was performed from May to July 2020 with a non-probability sample size of 98 diabetics. The bulk of responders were aged 40 - 60 (36.7%). Type 2 was the most common (47.96%). 44.9% of respondents had diabetes for more than ten years. 60.2% had regular checkups, and 54.1 percent had therapy. 52% of participants were on a diet. 63.3% of respondents do not exercise often. However, most responders know the common issues (75%). Less than half of those polled had problems (41.8%). 22% incidence of Diabetic ketoacidosis. 78.6% of respondents know variables that decrease diabetes complications, whereas 22.4% do not. 37.8% of respondents saw a doctor for diabetes problems, whereas 62.2% did not. Diabetic patients’ knowledge, attitude, and practice were satisfactory for fundamental illness entanglements and self-testing. These findings may also be due to patient notification and, therefore, long-term illness that leads them to get acquainted with things alone. However, the tendency for regular exercise was low, which may produce more specific consequences of illness. <strong>Conclusion:</strong> We find that DM patients’ KAP was adequate in terms of knowledge of diabetic complications. These results may explain the patients’ long-standing illness, which forces them to discover things independently. At the same time, just a handful of them were familiar with vasculopathy and cardiovascular disorders. However, the researchers discovered low level of attitudes and practice toward regular exercise and insufficient levels of attitudes and practice toward diet management and treatment adherence. In general, this degree of KAP is suboptimal and requires further assessment of KAP obstacles in Somalia.展开更多
文摘AIM： To investigate the incidence of various types of postoperative pulmonary complications （POPCs） and to evaluate the significance of perioperative arterial blood gases in patients with esophageal cancer accompanied with chronic obstructive pulmonary disease （COPD） after esophagectomy. MEHTODS： Three hundred and fifty-eight patients were divided into POPC group and COPD group. We performed a retrospective review of the 358 consecutive patients after esophagectomy for esophageal cancer with or without COPD to assess the possible influence of COPD on postoperative pulmonary complications. We classified COPD into four grades according to percent-predicted forced expiratory volume in 1 s （FEV1） and analyzed the incidence rate of complications among the four grades. Perioperative arterial blood gases were tested in patients with or without pulmonary complications in COPD group and compared with POP（： group. RESULTS： Patients with COPD （29/86, 33.7%）had more pulmonary complications than those without COPD （36/272, 13.2%） （P〈0.001）. Pneumonia （15/29, 51.7%）, atelectasis （13/29, 44.8%）, prolonged 02 supplement （10/29, 34.5%）, and prolonged mechanical ventilation （8/29, 27.6%） were the major complications in COPD group. Moreover, patients with severe COPD （grade Ⅱ B, FEV1 〈 50% of predicted） had more POPCs than those with moderate（gradeⅡA,50%-80% of predicted） and mild （grade Ⅰ≥80% of predicted） COPD （P〈0.05）. PaO2 was decreased and PaCO2 was increased in patients with pulmonary complications in COPD group in the first postoperative week.CONCLUSION： The criteria of COPD are the critical predictor for pulmonary complications in esophageal cancer patients undergoing esophagectomy. Severity of COPD affects the incidence rate of the pulmonary complication,and percent-predicted FEV1 is a good predictive variable for pulmonary complication in patients-with COPD.Arterial blood gases are helpful in directing perioperative management.
文摘目的分析慢性阻塞性肺疾病急性加重期(acute exacerbation phase of chronic obstructive pulmonary disease,AECOPD)炎症介质与肺功能的相关性。方法选取2021年6月—2023年6月泰州市姜堰中医院收治的110例AECOPD患者为加重组,另外选取71例COPD患者作为稳定组,选取同期健康体检者67例作为对照组。观察3组患者一般资料、检测患者炎症介质、肺功能指标。分析不同肺功能分级患者炎症介质、肺功能指标水平,并分析炎症介质与肺功能的相关性。结果与对照组相比,稳定组、加重组患者舒张压、收缩压、血肌酐、空腹血糖、白细胞(white blood cell,WBC)、降钙素原(procalcitonin,PCT)、超敏C反应蛋白(hypersensitive c reactive protein,hs-CRP)、白介素-6(interleukin-6,IL-6)、血清淀粉样蛋白A(serum amyloid A,SAA)表达水平逐渐升高,第1秒用力呼气容量/用力肺活量比值(forced expiratory volume in the first second/forced vital capacity,FEV1/FVC)、第1秒用力呼气容量(forced expiratory volume in the first second,FEV1)表达水平逐渐降低(P<0.05)。与Ⅰ级相比,Ⅱ级、Ⅲ级患者PCT、hs-CRP、IL-6、SAA表达水平逐渐升高,FEV1/FVC、FEV1水平逐渐降低(P<0.05)。相关性分析显示,FEV1/FVC、FEV1水平与PCT、hs-CRP、IL-6、SAA呈负相关(P<0.05)。多因素logistic回归分析显示,舒张压、收缩压、血肌酐、空腹血糖、WBC水平为AECOPD的主要危险因素(P<0.05)。结论AECOPD患者肺功能与炎症介质相关,检测患者炎症介质、肺功能状态,可用于患者病情的评估。
文摘<em>Diabetes </em>is a chronic illness that occurs when the pancreas stops producing insulin or when the body cannot use the produced insulin. <em>Insulin</em> is a hormone produced by the pancreas that helps glucose from meals enters the body’s cells for energy. The overall goal is to assess diabetes patients’ knowledge, attitudes, and behaviors about prevalent diabetic complications. This research used a descriptive qualitative methodology to assess diabetes complication knowledge, attitude, and practice. Ninety-eight diabetic patients were visiting the Egyptian Hospital in Mogadishu for four weeks. The data was collected using questionnaires. Finally, SPSS 20 was utilized for analysis. The research was performed from May to July 2020 with a non-probability sample size of 98 diabetics. The bulk of responders were aged 40 - 60 (36.7%). Type 2 was the most common (47.96%). 44.9% of respondents had diabetes for more than ten years. 60.2% had regular checkups, and 54.1 percent had therapy. 52% of participants were on a diet. 63.3% of respondents do not exercise often. However, most responders know the common issues (75%). Less than half of those polled had problems (41.8%). 22% incidence of Diabetic ketoacidosis. 78.6% of respondents know variables that decrease diabetes complications, whereas 22.4% do not. 37.8% of respondents saw a doctor for diabetes problems, whereas 62.2% did not. Diabetic patients’ knowledge, attitude, and practice were satisfactory for fundamental illness entanglements and self-testing. These findings may also be due to patient notification and, therefore, long-term illness that leads them to get acquainted with things alone. However, the tendency for regular exercise was low, which may produce more specific consequences of illness. <strong>Conclusion:</strong> We find that DM patients’ KAP was adequate in terms of knowledge of diabetic complications. These results may explain the patients’ long-standing illness, which forces them to discover things independently. At the same time, just a handful of them were familiar with vasculopathy and cardiovascular disorders. However, the researchers discovered low level of attitudes and practice toward regular exercise and insufficient levels of attitudes and practice toward diet management and treatment adherence. In general, this degree of KAP is suboptimal and requires further assessment of KAP obstacles in Somalia.
