Beirang brand dyestuff is the product of the Beijing Dyestuff Plant,a large and key chemical enterprise recognized by the Ministry of Chemical Industry, producing dyestuff for production,organic pigment and industrial...Beirang brand dyestuff is the product of the Beijing Dyestuff Plant,a large and key chemical enterprise recognized by the Ministry of Chemical Industry, producing dyestuff for production,organic pigment and industrial sulfuric acid. Some 1,200 tons of State level quality Beirang brand blue pigment is produced in granule and powder form展开更多
The biosynthetic investigations of microbial natural products continuously provide powerful biocatalysts for the preparation of valuable chemicals.Practical methods for preparing(S)-3-aminopiperidine-2,6-dione(2),the ...The biosynthetic investigations of microbial natural products continuously provide powerful biocatalysts for the preparation of valuable chemicals.Practical methods for preparing(S)-3-aminopiperidine-2,6-dione(2),the pharmacophore of thalidomide(1)and its analog drugs,are highly desired.To develop a biocatalyst for producing(S)-2,we dissected the domain functions of IdgS,which is responsible for the biosynthesis of indigoidine(3),a microbial blue pigment that consists of two 2-like moieties.Our data supported that the L-glutamine tethered to the indigoidine assembly line is first offloaded and cyclized by the thioesterase domain to form(S)-2,which is then dehydrogenated by the oxidation(Ox)domain and finally dimerized to yield 3.Based on this,we developed an IdgS-derived enzyme biocatalyst,IdgS-Ox^(*)R539A,for preparing enantiomerically pure(S)-2.As a proof of concept,one-pot chemoenzymatic synthesis of 1 was achieved by combining the biocatalytic and chemical approaches.展开更多
Based on the conclusion of modern scientific analysis: the cobalt-blue pigment applied on Jingdezhen official porcelain during Yuan Dynasty and prior to Xuande reign of Ming Dynasty (1271―1425) contains high iron and...Based on the conclusion of modern scientific analysis: the cobalt-blue pigment applied on Jingdezhen official porcelain during Yuan Dynasty and prior to Xuande reign of Ming Dynasty (1271―1425) contains high iron and low manganese con- tents, and the cobalt during Xuande and after Xuande periods (after 1426) of Ming Dynasty contains high manganese and low iron contents, in combination with the traditional archaeological method, the related historical textual records were in- vestigated and analyzed, the imported cobalt employed on Jingdezhen official porcelain was studied comprehensively, systematically and logically. In fact, 'Su Ma Li Qing' (Samarra-blue) and 'Su Bo Ni Qing' (Sumatra-blue) are definitely different cobalt ores originated in different places, because of their very similar translitera- tions in Chinese, the confusion has appeared in ancient books for more than 400 years, which considered 'Su Ma Li Qing' and 'Su Bo Ni Qing' as the same co- balt-blue pigment. In this article the mistake was corrected, the possible producing places and the approximate eras of the two pigments imported to China and used at Jingdezhen were also suggested.展开更多
The ability to track & trace materials is a key feature in the entire chain, and it ensures circularity principles. Examples from plastic recycling show the enormous added value that analytical technology can have...The ability to track & trace materials is a key feature in the entire chain, and it ensures circularity principles. Examples from plastic recycling show the enormous added value that analytical technology can have for the circular economy. During polymer production and recycling processes, pigments can be added for different purposes;e.g. as colouring agent of the polymeric product but also as tracer for tracking process development and control in the final recycle products versus possible by-products. An analytical method for tracking the pigment Solvent Blue 15 in input materials, in intermediates as well as in recyclates was developed by tracing and quantifying an indicator metal which is copper (Cu). Therefore, suitable digestion procedures and a quantification method by high resolution inductively coupled plasma mass spectrometry (HR-ICP-MS) were developed and used for measuring the polymeric digests. The method was tested on relevant samples from chemical recycling processes. The background concentrations in base/raw material are in the range of 0.05 - 0.1 mg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;">·</span>kg<span style="font-family:'Verdana, Helvetica, Arial';"><span style="background-color:#FFFFFF;"><sup>-1<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"></span></sup></span></span> Cu. The processing concentrations are in the range of 4.2 to 28 mg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;">·</span>kg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><sup>-1</sup></span><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"></span></span> Cu, while the pigment starting material (polyethylene, PE) has a concentration of around 50 mg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;">·</span>kg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><sup>-1</sup></span><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"></span></span> Cu.展开更多
为鉴定影响蛋壳色素含量的基因组拷贝数变异,试验以长顺绿壳蛋鸡为研究对象,依据蛋壳表型设置2个试验组:B2 vs B1和B3 vs B1,通过CGH芯片全基因组检测筛选和Ac⁃cuCopyTM多重基因拷贝数检测验证,在全基因组范围内进行鉴定,选择其中12个...为鉴定影响蛋壳色素含量的基因组拷贝数变异,试验以长顺绿壳蛋鸡为研究对象,依据蛋壳表型设置2个试验组:B2 vs B1和B3 vs B1,通过CGH芯片全基因组检测筛选和Ac⁃cuCopyTM多重基因拷贝数检测验证,在全基因组范围内进行鉴定,选择其中12个注释功能基因开展关联验证。结果显示:两个试验组分别检测到绿壳表型差异关联区域22个和24个;腺苷酸环化酶10(ADCY10)基因拷贝数变异与原卟啉色素含量呈极显著负相关(R=-0.424,P=0.001),与胆绿素色素含量呈显著正相关(R=0.299,P=0.018)。研究提示,ADCY10基因可能是影响蛋壳中不同色素含量的关键基因之一。展开更多
文摘Beirang brand dyestuff is the product of the Beijing Dyestuff Plant,a large and key chemical enterprise recognized by the Ministry of Chemical Industry, producing dyestuff for production,organic pigment and industrial sulfuric acid. Some 1,200 tons of State level quality Beirang brand blue pigment is produced in granule and powder form
基金supported in part by the National Key R&D Program of China(2020YFA0907700)the NSFC grants(32025002 and 31522001).
文摘The biosynthetic investigations of microbial natural products continuously provide powerful biocatalysts for the preparation of valuable chemicals.Practical methods for preparing(S)-3-aminopiperidine-2,6-dione(2),the pharmacophore of thalidomide(1)and its analog drugs,are highly desired.To develop a biocatalyst for producing(S)-2,we dissected the domain functions of IdgS,which is responsible for the biosynthesis of indigoidine(3),a microbial blue pigment that consists of two 2-like moieties.Our data supported that the L-glutamine tethered to the indigoidine assembly line is first offloaded and cyclized by the thioesterase domain to form(S)-2,which is then dehydrogenated by the oxidation(Ox)domain and finally dimerized to yield 3.Based on this,we developed an IdgS-derived enzyme biocatalyst,IdgS-Ox^(*)R539A,for preparing enantiomerically pure(S)-2.As a proof of concept,one-pot chemoenzymatic synthesis of 1 was achieved by combining the biocatalytic and chemical approaches.
文摘Based on the conclusion of modern scientific analysis: the cobalt-blue pigment applied on Jingdezhen official porcelain during Yuan Dynasty and prior to Xuande reign of Ming Dynasty (1271―1425) contains high iron and low manganese con- tents, and the cobalt during Xuande and after Xuande periods (after 1426) of Ming Dynasty contains high manganese and low iron contents, in combination with the traditional archaeological method, the related historical textual records were in- vestigated and analyzed, the imported cobalt employed on Jingdezhen official porcelain was studied comprehensively, systematically and logically. In fact, 'Su Ma Li Qing' (Samarra-blue) and 'Su Bo Ni Qing' (Sumatra-blue) are definitely different cobalt ores originated in different places, because of their very similar translitera- tions in Chinese, the confusion has appeared in ancient books for more than 400 years, which considered 'Su Ma Li Qing' and 'Su Bo Ni Qing' as the same co- balt-blue pigment. In this article the mistake was corrected, the possible producing places and the approximate eras of the two pigments imported to China and used at Jingdezhen were also suggested.
文摘The ability to track & trace materials is a key feature in the entire chain, and it ensures circularity principles. Examples from plastic recycling show the enormous added value that analytical technology can have for the circular economy. During polymer production and recycling processes, pigments can be added for different purposes;e.g. as colouring agent of the polymeric product but also as tracer for tracking process development and control in the final recycle products versus possible by-products. An analytical method for tracking the pigment Solvent Blue 15 in input materials, in intermediates as well as in recyclates was developed by tracing and quantifying an indicator metal which is copper (Cu). Therefore, suitable digestion procedures and a quantification method by high resolution inductively coupled plasma mass spectrometry (HR-ICP-MS) were developed and used for measuring the polymeric digests. The method was tested on relevant samples from chemical recycling processes. The background concentrations in base/raw material are in the range of 0.05 - 0.1 mg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;">·</span>kg<span style="font-family:'Verdana, Helvetica, Arial';"><span style="background-color:#FFFFFF;"><sup>-1<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"></span></sup></span></span> Cu. The processing concentrations are in the range of 4.2 to 28 mg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;">·</span>kg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><sup>-1</sup></span><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"></span></span> Cu, while the pigment starting material (polyethylene, PE) has a concentration of around 50 mg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;">·</span>kg<span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"><sup>-1</sup></span><span style="font-family:Verdana, Helvetica, Arial;white-space:normal;background-color:#FFFFFF;"></span></span> Cu.
文摘为鉴定影响蛋壳色素含量的基因组拷贝数变异,试验以长顺绿壳蛋鸡为研究对象,依据蛋壳表型设置2个试验组:B2 vs B1和B3 vs B1,通过CGH芯片全基因组检测筛选和Ac⁃cuCopyTM多重基因拷贝数检测验证,在全基因组范围内进行鉴定,选择其中12个注释功能基因开展关联验证。结果显示:两个试验组分别检测到绿壳表型差异关联区域22个和24个;腺苷酸环化酶10(ADCY10)基因拷贝数变异与原卟啉色素含量呈极显著负相关(R=-0.424,P=0.001),与胆绿素色素含量呈显著正相关(R=0.299,P=0.018)。研究提示,ADCY10基因可能是影响蛋壳中不同色素含量的关键基因之一。