The present study aimed to estimate the occurrence of Iron Deficiency anemia (IDA) in school and college going students (aged 11 - 18 years). Anemia is the most public health problem in school age children. It has a w...The present study aimed to estimate the occurrence of Iron Deficiency anemia (IDA) in school and college going students (aged 11 - 18 years). Anemia is the most public health problem in school age children. It has a wide range of adverse results involving, poor cognitive performance, poor development of infants, preschool and school-aged children. Anemia also causes the impairment of physical capacity, work performance of adolescents and adults, reduction in immune competence and increased morbidity from infections in all age groups. Our study based on 1686 volunteers was randomly selected from different Government High schools and colleges. A Questionnaire was utilized for data collection. BMI was also calculated by dividing weight in kg by the square of height in meters. Hemoglobin (Hb), Hematocrite (Hct), Mean Corpuscular volume (MCV), Mean Corpuscular hemoglobin concentration (MCHC), white blood cell (WBC) and red blood cell was examined using Sysmex kx-21N hemoglobin auto analyzer (Hedwin, 2008). The total percentage of anaemic students (43.1%) and non-anaemic (56.9%) were observed in district Shaheed Benazirabad. The mean Hb level of anaemic students (11.1 ± 4.94) was observed. In males (12.7%) and females (30.4%) anemic was observed. The prevalence of anemia high (16.2%) was observed in the age of 14 - 16 years. The majority of anemic patients (30.2%) belonged to low income group. Area wise prevalence, in rural areas 27.8% and urban areas 15.3% volunteers anaemic was observed. Taluka wise occurrence of anaemia in taluka Sakrand was (14.6%), in taluka Kazi Ahmed (15.0%), in taluka Daur (8.0%) and in taluka Nawabshah was (5.5%). Clinically signs and symptoms showed, pale skin 57.7% and weakness 42.3% were observed in school children.展开更多
AIM To identify the predictors of vitamin D deficiency in patients with and without inflammatory bowel disease(IBD).METHODS Patients with ulcerative colitis(UC) or Crohn's disease(CD) related diagnostic codes who ...AIM To identify the predictors of vitamin D deficiency in patients with and without inflammatory bowel disease(IBD).METHODS Patients with ulcerative colitis(UC) or Crohn's disease(CD) related diagnostic codes who received medical care at University of Mississippi Medical Center between July 2012 and 2015 were identified. After thorough chart review, we identified patients with biopsy proven IBD who had also been tested for serum 25-hydroxyvitamin D [25(OH)D] concentration. We compared these patients to a previously studied cohort of healthy controls who also had vitamin D concentration checked. Logistic regression analysis was performed to determine the association between vitamin d deficiency and UC, CD, race, age, gender and body mass index(BMI).RESULTS We identified 237 patients with confirmed IBD. Of these, only 211 had a serum 25(OH)D concentrations available in the medical record. The group of healthy controls consisted of 98 individuals with available serum 25(OH)D concentration. 43% of IBD patients were African American(AA). Patients with CD were more likely to have vitamin D concentration checked. Bivariate analysis showed that AA(51% vs 21%, P= 0.00001), subjects with BMI > 30 kg/m^2(39% vs 23% P = 0.01) and CD(40% vs 26%, P = 0.04) were more likely to be vitamin D deficient than vitamin D sufficient. Those with Age > 65 were more likely to be vitamin D sufficient(46% vs 15%, P = 0.04). Multiple regression showed that only BMI > 30 kg/m^2 and AA race are associated with vitamin D deficiency. CONCLUSION BMI > 30 kg/m^2 and AA race are predictive of vitamin D deficiency. Gender, age and diagnosis of IBD are not predictive of vitamin D deficiency.展开更多
Objective:To explore the relationship among body mass index(BMI),dosage of progesterone(P) and serum progesterone concentration,and provide reference for the clinical use of oral progesterone. Methods:This was a rando...Objective:To explore the relationship among body mass index(BMI),dosage of progesterone(P) and serum progesterone concentration,and provide reference for the clinical use of oral progesterone. Methods:This was a random,open-label,prospective clinical trial.Eighty women meeting the criteria for enrollment were recruited from July 2010 to March 2011 in outpatient clinic of Peking Union Medical College Hospital and given oral progesterone therapy for consecutive 10 days.They were randomly assigned into four groups according to the different doses of progesterone:group A 100 mg/day,group B 200 mg/day,group C 300 mg/day and group D 400 mg/day. Results:Seventy four patients(92.5%,74/80) accomplished the study.It can be observed that administration of different dosage of P could significantly increase serum P concentration(all P<0.001).And there was a positive correlation between the increase of P concentration and dosage(r_p=0.613,P<0.001).Furthermore,the medians of the increase of serum P concentration in 4 groups were 14.71 nmol/L in group A,28.47 nmol/L in group B, 58.89 nmol/L in group C,72.69 nmol/L in group D.When BMI<24 kg/m^2(42 cases),the median of the increase of P levels was 13.90 nmol/L,37.22 nmol/L,62.55 nmol/L,and 119.02 nmol/L in group A,B,C and D, respectively,while BMI≥24 kg/m^2(32 cases),the median of increase was 8.93 nmol/L,24.82 nmol/L,24.87 nmol/L,and 63.48 nmol/L,respectively.In addition,significant difference was found only in group D between women with BMI<24 kg/m^2 and with BMI≥24 kg/m^2(P = 0.010). Conclusions;Serum progesterone levels go up linearly with the dosage increasing.The greater BMI the patient have,the larger dosage may be needed to achieve the same serum progesterone concentration.The individual dosage of oral progesterone needed can be roughly calculated in the light of the result of this study.展开更多
目的探讨健脾消痰方结合常规减肥措施治疗脾虚痰湿型肥胖症临床效果。方法按照随机数表法将92例脾虚痰湿型肥胖症患者分成对照组和观察组,各46例。对照组采用调整饮食生活方式减肥方法,观察组在对照组常规减肥措施基础上联合健脾消痰方...目的探讨健脾消痰方结合常规减肥措施治疗脾虚痰湿型肥胖症临床效果。方法按照随机数表法将92例脾虚痰湿型肥胖症患者分成对照组和观察组,各46例。对照组采用调整饮食生活方式减肥方法,观察组在对照组常规减肥措施基础上联合健脾消痰方治疗。观察2组治疗前后临床症状积分(食少纳呆、脘腹痞闷、头身困重、大便溏泄)、身体质量指数(BMI)、腰围、臀围、空腹血糖(FBG)、餐后2 h血糖(2 hFBG)、血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)、白细胞介素1β(IL^(-1)β)、白细胞介素6(IL-6)、肿瘤坏死因子α(TNF-α)水平变化情况,并比较2组治疗总有效率及安全性。结果观察组治疗后BMI、腰围、臀围、FBG、2 h FBG、TG、TC、LDL-C水平,IL-6、IL^(-1)β、TNF-α水平均低于对照组(P<0.05),HDL-C水平、治疗总有效率均高于对照组(P<0.05);2组均无明显用药不良反应发生。结论健脾消痰方结合常规减肥措施治疗脾虚痰湿型肥胖症疗效确切,安全有效,能够有效调节糖脂代谢紊乱,抑制炎性因子表达,减轻肥胖程度。展开更多
[目的]探讨改良Z-Track肌内注射法在体外受精-胚胎移植(IVF-ET)病人黄体酮注射中的应用效果。[方法]采用前瞻性随机对照研究方法,将纳入研究的122例IVF-ET病人按照随机数字表法分为观察组和对照组各61例。对照组采用常规肌内注射法,观...[目的]探讨改良Z-Track肌内注射法在体外受精-胚胎移植(IVF-ET)病人黄体酮注射中的应用效果。[方法]采用前瞻性随机对照研究方法,将纳入研究的122例IVF-ET病人按照随机数字表法分为观察组和对照组各61例。对照组采用常规肌内注射法,观察组根据病人不同体质指数,采用改良Z-Track肌内注射法。比较两组给药7 d内注射部位不良反应发生情况。[结果]观察组局部硬结发生率显著低于对照组,组间比较差异有统计学意义(χ 2=6.917, P <0.05);观察组疼痛程度显著低于对照组,组间比较差异有统计学意义( Z =6.622, P <0.05)。[结论]根据病人不同体质指数,采用改良Z-Track肌内注射法进行黄体酮臀部肌内注射,可有效减少局部不良反应,确保用药安全。展开更多
文摘The present study aimed to estimate the occurrence of Iron Deficiency anemia (IDA) in school and college going students (aged 11 - 18 years). Anemia is the most public health problem in school age children. It has a wide range of adverse results involving, poor cognitive performance, poor development of infants, preschool and school-aged children. Anemia also causes the impairment of physical capacity, work performance of adolescents and adults, reduction in immune competence and increased morbidity from infections in all age groups. Our study based on 1686 volunteers was randomly selected from different Government High schools and colleges. A Questionnaire was utilized for data collection. BMI was also calculated by dividing weight in kg by the square of height in meters. Hemoglobin (Hb), Hematocrite (Hct), Mean Corpuscular volume (MCV), Mean Corpuscular hemoglobin concentration (MCHC), white blood cell (WBC) and red blood cell was examined using Sysmex kx-21N hemoglobin auto analyzer (Hedwin, 2008). The total percentage of anaemic students (43.1%) and non-anaemic (56.9%) were observed in district Shaheed Benazirabad. The mean Hb level of anaemic students (11.1 ± 4.94) was observed. In males (12.7%) and females (30.4%) anemic was observed. The prevalence of anemia high (16.2%) was observed in the age of 14 - 16 years. The majority of anemic patients (30.2%) belonged to low income group. Area wise prevalence, in rural areas 27.8% and urban areas 15.3% volunteers anaemic was observed. Taluka wise occurrence of anaemia in taluka Sakrand was (14.6%), in taluka Kazi Ahmed (15.0%), in taluka Daur (8.0%) and in taluka Nawabshah was (5.5%). Clinically signs and symptoms showed, pale skin 57.7% and weakness 42.3% were observed in school children.
文摘AIM To identify the predictors of vitamin D deficiency in patients with and without inflammatory bowel disease(IBD).METHODS Patients with ulcerative colitis(UC) or Crohn's disease(CD) related diagnostic codes who received medical care at University of Mississippi Medical Center between July 2012 and 2015 were identified. After thorough chart review, we identified patients with biopsy proven IBD who had also been tested for serum 25-hydroxyvitamin D [25(OH)D] concentration. We compared these patients to a previously studied cohort of healthy controls who also had vitamin D concentration checked. Logistic regression analysis was performed to determine the association between vitamin d deficiency and UC, CD, race, age, gender and body mass index(BMI).RESULTS We identified 237 patients with confirmed IBD. Of these, only 211 had a serum 25(OH)D concentrations available in the medical record. The group of healthy controls consisted of 98 individuals with available serum 25(OH)D concentration. 43% of IBD patients were African American(AA). Patients with CD were more likely to have vitamin D concentration checked. Bivariate analysis showed that AA(51% vs 21%, P= 0.00001), subjects with BMI > 30 kg/m^2(39% vs 23% P = 0.01) and CD(40% vs 26%, P = 0.04) were more likely to be vitamin D deficient than vitamin D sufficient. Those with Age > 65 were more likely to be vitamin D sufficient(46% vs 15%, P = 0.04). Multiple regression showed that only BMI > 30 kg/m^2 and AA race are associated with vitamin D deficiency. CONCLUSION BMI > 30 kg/m^2 and AA race are predictive of vitamin D deficiency. Gender, age and diagnosis of IBD are not predictive of vitamin D deficiency.
文摘Objective:To explore the relationship among body mass index(BMI),dosage of progesterone(P) and serum progesterone concentration,and provide reference for the clinical use of oral progesterone. Methods:This was a random,open-label,prospective clinical trial.Eighty women meeting the criteria for enrollment were recruited from July 2010 to March 2011 in outpatient clinic of Peking Union Medical College Hospital and given oral progesterone therapy for consecutive 10 days.They were randomly assigned into four groups according to the different doses of progesterone:group A 100 mg/day,group B 200 mg/day,group C 300 mg/day and group D 400 mg/day. Results:Seventy four patients(92.5%,74/80) accomplished the study.It can be observed that administration of different dosage of P could significantly increase serum P concentration(all P<0.001).And there was a positive correlation between the increase of P concentration and dosage(r_p=0.613,P<0.001).Furthermore,the medians of the increase of serum P concentration in 4 groups were 14.71 nmol/L in group A,28.47 nmol/L in group B, 58.89 nmol/L in group C,72.69 nmol/L in group D.When BMI<24 kg/m^2(42 cases),the median of the increase of P levels was 13.90 nmol/L,37.22 nmol/L,62.55 nmol/L,and 119.02 nmol/L in group A,B,C and D, respectively,while BMI≥24 kg/m^2(32 cases),the median of increase was 8.93 nmol/L,24.82 nmol/L,24.87 nmol/L,and 63.48 nmol/L,respectively.In addition,significant difference was found only in group D between women with BMI<24 kg/m^2 and with BMI≥24 kg/m^2(P = 0.010). Conclusions;Serum progesterone levels go up linearly with the dosage increasing.The greater BMI the patient have,the larger dosage may be needed to achieve the same serum progesterone concentration.The individual dosage of oral progesterone needed can be roughly calculated in the light of the result of this study.
文摘目的探讨健脾消痰方结合常规减肥措施治疗脾虚痰湿型肥胖症临床效果。方法按照随机数表法将92例脾虚痰湿型肥胖症患者分成对照组和观察组,各46例。对照组采用调整饮食生活方式减肥方法,观察组在对照组常规减肥措施基础上联合健脾消痰方治疗。观察2组治疗前后临床症状积分(食少纳呆、脘腹痞闷、头身困重、大便溏泄)、身体质量指数(BMI)、腰围、臀围、空腹血糖(FBG)、餐后2 h血糖(2 hFBG)、血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)、白细胞介素1β(IL^(-1)β)、白细胞介素6(IL-6)、肿瘤坏死因子α(TNF-α)水平变化情况,并比较2组治疗总有效率及安全性。结果观察组治疗后BMI、腰围、臀围、FBG、2 h FBG、TG、TC、LDL-C水平,IL-6、IL^(-1)β、TNF-α水平均低于对照组(P<0.05),HDL-C水平、治疗总有效率均高于对照组(P<0.05);2组均无明显用药不良反应发生。结论健脾消痰方结合常规减肥措施治疗脾虚痰湿型肥胖症疗效确切,安全有效,能够有效调节糖脂代谢紊乱,抑制炎性因子表达,减轻肥胖程度。
文摘[目的]探讨改良Z-Track肌内注射法在体外受精-胚胎移植(IVF-ET)病人黄体酮注射中的应用效果。[方法]采用前瞻性随机对照研究方法,将纳入研究的122例IVF-ET病人按照随机数字表法分为观察组和对照组各61例。对照组采用常规肌内注射法,观察组根据病人不同体质指数,采用改良Z-Track肌内注射法。比较两组给药7 d内注射部位不良反应发生情况。[结果]观察组局部硬结发生率显著低于对照组,组间比较差异有统计学意义(χ 2=6.917, P <0.05);观察组疼痛程度显著低于对照组,组间比较差异有统计学意义( Z =6.622, P <0.05)。[结论]根据病人不同体质指数,采用改良Z-Track肌内注射法进行黄体酮臀部肌内注射,可有效减少局部不良反应,确保用药安全。
