It is well-documented that male overweight and obesity causes endocrine disorders that might diminish the male reproductive capacity; however, reports have been conflicting regarding the influence of male body mass in...It is well-documented that male overweight and obesity causes endocrine disorders that might diminish the male reproductive capacity; however, reports have been conflicting regarding the influence of male body mass index （BMI） on semen quality and the outcome of assisted reproductive technology （ART）. The aim of this study was to investigate whether increased male BMI affects sperm quality and the outcome of assisted reproduction in couples with an overweight or obese man and a non-obese partner. Data was prospectively collected from 612 infertile couples undergoing ART at a Danish fertility center. Self-reported information on paternal height and weight were recorded and BMI was calculated. The men were divided into four BMI categories： underweight BMI 〈 20 kgm^-2, normal BMI 20-24.9 kg m^-2, overweight BMI 25-29.9 kgm^-2 and obese BMI 〉 30 kgm^-2. Conventional semen analysis was performed according to the World Health Organization guideline and sperm DNA integrity was analyzed by the Sperm Chromatin Structure Assay （SCSA）. No statistically significant effect of male BMI was seen on conventional semen parameters （sperm concentration, total sperm count, seminal volume and motility） or on SCSA-results. Furthermore, the outcome of ART regarding fertilization rate, number of good quality embryos （GQE）, implantation and pregnancy outcome was not influenced by the increasing male BMIo展开更多
through the teaching design of online course quality and application practice, the instructional design process based on B/S learning are analyzed, and discusses several key problems in the design and teaching. The pr...through the teaching design of online course quality and application practice, the instructional design process based on B/S learning are analyzed, and discusses several key problems in the design and teaching. The proposed resource-based learning teaching design network course should adapt to the application mode of network teaching and traditional classroom combination; will provide teaching demonstration, teaching content self testing evaluation for students, and to provide jobs for teachers management, online Q ＆ A, BBS, database and knowledge construction and other functions, greatly improving the efficiency of teaching ＂excellent course＂ .展开更多
利用裂纹扩展分析方法和质量分类法研究铝合金车体含缺欠焊接结构的疲劳寿命问题。首先,研究IIW:2015的基于Paris定律的裂纹扩展分析的理论基础和BS 7910:2019的基于考虑焊接缺欠质量的S-N曲线的质量分类法的算法原理;其次,归纳总结了这...利用裂纹扩展分析方法和质量分类法研究铝合金车体含缺欠焊接结构的疲劳寿命问题。首先,研究IIW:2015的基于Paris定律的裂纹扩展分析的理论基础和BS 7910:2019的基于考虑焊接缺欠质量的S-N曲线的质量分类法的算法原理;其次,归纳总结了这2种方法进行考虑焊接质量的焊接结构疲劳寿命评估流程;再次,在疲劳载荷作用下,基于BS EN 1999-1-3:2007的名义应力法对某动车组铝合金车体进行疲劳分析,确定车体疲劳关切焊缝部位;最后,分别利用裂纹扩展分析方法和质量分类法对车体关切焊缝侧门下角进行考虑初始裂纹的疲劳寿命评估。结果表明:基于质量分类法的剩余寿命为1.4×106次,基于裂纹扩展分析法的剩余寿命为2.64×106次。展开更多
针对中国目前工程项目管理软件的开发现状与行业需求,开发一种以数据分析为主,以"项目诊断、质量监控、预警处理"为辅的大型集成化建设工程项目管理平台.从管理工具入手,将工程项目管理理论、集成化思想以及信息化技术相融合...针对中国目前工程项目管理软件的开发现状与行业需求,开发一种以数据分析为主,以"项目诊断、质量监控、预警处理"为辅的大型集成化建设工程项目管理平台.从管理工具入手,将工程项目管理理论、集成化思想以及信息化技术相融合,构建目标管理平台的系统框架;再利用计算机编程技术(VS 2005开发工具和C#编程语言)和数据库存储技术(SQL Server 2005),进行基于C/S模式工程项目管理平台的开发.研究结果表明:目标平台的应用着实在信息沟通与处理方面起到了一定的助导作用;此外,项目诊断、质量监控以及预警处理等功能模块还会分别给出各自的量化分析结果,为管理者解决问题提供客观的决策依据,切实保证了评价的科学性与信息的时效性.展开更多
文摘It is well-documented that male overweight and obesity causes endocrine disorders that might diminish the male reproductive capacity; however, reports have been conflicting regarding the influence of male body mass index （BMI） on semen quality and the outcome of assisted reproductive technology （ART）. The aim of this study was to investigate whether increased male BMI affects sperm quality and the outcome of assisted reproduction in couples with an overweight or obese man and a non-obese partner. Data was prospectively collected from 612 infertile couples undergoing ART at a Danish fertility center. Self-reported information on paternal height and weight were recorded and BMI was calculated. The men were divided into four BMI categories： underweight BMI 〈 20 kgm^-2, normal BMI 20-24.9 kg m^-2, overweight BMI 25-29.9 kgm^-2 and obese BMI 〉 30 kgm^-2. Conventional semen analysis was performed according to the World Health Organization guideline and sperm DNA integrity was analyzed by the Sperm Chromatin Structure Assay （SCSA）. No statistically significant effect of male BMI was seen on conventional semen parameters （sperm concentration, total sperm count, seminal volume and motility） or on SCSA-results. Furthermore, the outcome of ART regarding fertilization rate, number of good quality embryos （GQE）, implantation and pregnancy outcome was not influenced by the increasing male BMIo
文摘through the teaching design of online course quality and application practice, the instructional design process based on B/S learning are analyzed, and discusses several key problems in the design and teaching. The proposed resource-based learning teaching design network course should adapt to the application mode of network teaching and traditional classroom combination; will provide teaching demonstration, teaching content self testing evaluation for students, and to provide jobs for teachers management, online Q ＆ A, BBS, database and knowledge construction and other functions, greatly improving the efficiency of teaching ＂excellent course＂ .
文摘利用裂纹扩展分析方法和质量分类法研究铝合金车体含缺欠焊接结构的疲劳寿命问题。首先,研究IIW:2015的基于Paris定律的裂纹扩展分析的理论基础和BS 7910:2019的基于考虑焊接缺欠质量的S-N曲线的质量分类法的算法原理;其次,归纳总结了这2种方法进行考虑焊接质量的焊接结构疲劳寿命评估流程;再次,在疲劳载荷作用下,基于BS EN 1999-1-3:2007的名义应力法对某动车组铝合金车体进行疲劳分析,确定车体疲劳关切焊缝部位;最后,分别利用裂纹扩展分析方法和质量分类法对车体关切焊缝侧门下角进行考虑初始裂纹的疲劳寿命评估。结果表明:基于质量分类法的剩余寿命为1.4×106次,基于裂纹扩展分析法的剩余寿命为2.64×106次。
文摘针对中国目前工程项目管理软件的开发现状与行业需求,开发一种以数据分析为主,以"项目诊断、质量监控、预警处理"为辅的大型集成化建设工程项目管理平台.从管理工具入手,将工程项目管理理论、集成化思想以及信息化技术相融合,构建目标管理平台的系统框架;再利用计算机编程技术(VS 2005开发工具和C#编程语言)和数据库存储技术(SQL Server 2005),进行基于C/S模式工程项目管理平台的开发.研究结果表明:目标平台的应用着实在信息沟通与处理方面起到了一定的助导作用;此外,项目诊断、质量监控以及预警处理等功能模块还会分别给出各自的量化分析结果,为管理者解决问题提供客观的决策依据,切实保证了评价的科学性与信息的时效性.
