Photocatalytic C–X borylation of aryl halides by hierarchical SiC nanowire-supported Pd nanoparticles

Hierarchical Si C nanowire-supported Pd nanoparticles showed high photocatalytic activity for the C–X(X = Br, I) borylation of aryl halides at 30 °C. The Si C/Pd Mott-Schottky contact enhances the rapid transfer of the photogenerated electrons from Si C to the Pd nanoparticles. As a result, the concentrated energetic electrons in the Pd nanoparticles can facilitate the cleavage of C–I or C–Br bonds, which normally requires high-temperature thermal processes. We show that the present Pd/Si C photocatalyst is capable of catalyzing the transformation of a large variety of aryl halides to their corresponding boronate esters under visible light irradiation, with excellent yields.

"Solid-Liquid" Vitrimers Based on Dynamic Boronic Ester Networks

The"solid-liquid"behavior of vitrimers have not been systematically investigated.Herein,a series of"solid-liquid"vitrimers bearing varying contents of dynamic boronic ester bonds were synthesized via thiol-ene click reactions.These vitrimers allow for flexibile modulation of their network structures and thus show a range of intriguing properties including high stretchability,flexible transition from elasticity to plasticity,strong strain rate dependence,and solid-liquid performance.The dynamic association rate of boronic ester bonds within these vitrimers could be apparently accelerated via increasing the content of boronic ester,which could be used to shape-program the flat vitrimer films into various complex 3D structures just with external force.Materials with such versatile dynamic behavior may open up a range of new applications.

Cu2O-Mediated Room Temperature Cyanation of Aryl Boronic Acids/Esters and TMSCN

A method for the efficient and reliable synthesis of aryl nitriles via the Cu20-catalyed cross-coupling of aryl boronic acids or esters and TMSCN is presented. A broad range of substrates decorated by electron-rich and defi- cient, sterically very congested, and labile functionalities were tolerated. Moreover, the reaction can proceed under mild conditions at room temperature. These advantages paired with the use of cheap, readily available, and halo- gen-free Cu20 as catalysts make the protocol an appealing option for aryl cyanations.

Electrochemically promoted decarboxylative borylation of alkyl N-hydroxyphthalimide esters

An electrochemically promoted decarboxylative borylation reaction is reported. The reaction proceeds under mild conditions in an undivided cell without use of transition metal-or photo-catalysts. The key feature of the reaction is the compatibility of diboron reagents with the electrochemical conditions. This reaction exhibits broad substrate scope, good functional group tolerability, and easy scalability.

Design of a novel mitochondria targetable turn-on fluorescence probe for hydrogen peroxide and its two-photon bioimaging applications

Considering that hydrogen peroxide(H2O2)plays significant roles in oxidative stress,the cellular signal transduction and essential biological process regulation,the detection and imaging of H2O2 in living systems undertakes critical responsibility.Herein,we have developed a novel two-photon fluorescence turn on probe,named as Pyp-B for mitochondria H2O2 detection in living systems.Selectivity studies show that probe Pyp-B exhibit highly sensitive response toward H2O2 than other reactive oxygen species(ROS)and reactive nitrogen species(RNS)as well as biologically relevant species.The fluorescence colocalization studies demonstrate that the probe can localize in the mitochondria solely.Furthermore,as a bio-compatibility molecule,the highly selective and sensitive of fluorescence probe Pyp-B have been confirmed by its cell imaging application of H2O2 in living A549 cells and zebrafishes under the physiological conditions.

Expedient copper-catalyzed borylation reactions using amino acids as ligands

Amino acids were found to be as good ligands for copper-catalyzed borylation reactions of primary and secondary alkyl halides,and the B2pin2 acted as bi-boron source for borylation.The high reaction efficiency and mild conditions make the new catalyst system a useful alternative to the recently developed methods for the preparation of alkylboronic esters.