It is well known that calcium channel blockers(CCBs) are the first line of therapy for vasospastic angina(VSA). Here, we report two cases of VSA with an increase in the frequency of angina attacks after switching from...It is well known that calcium channel blockers(CCBs) are the first line of therapy for vasospastic angina(VSA). Here, we report two cases of VSA with an increase in the frequency of angina attacks after switching from a brand-name to a generic CCB. In both cases, angina recurred upon switching from a brand-name CCB to a generic CCB during follow-up. The patients' condition improved upon switching back to the original CCB. Both cases involved a high severity of VSA, based on the results of spasm provocation testing. These findings suggest that, in some patients with severe VSA, the frequency of angina attacks increases when switching from a brand-name CCB to a generic CCB. Cardiologists should consider this factor when prescribing drugs for angina.展开更多
China’s light industry hasdeveloped rapidly since thereform and opening drivebegan.In 1994,the total outputvalue of light industry wasRMB490.2 billion,and theexport volume of lightindustrial products wasUS＄35.6 bill...China’s light industry hasdeveloped rapidly since thereform and opening drivebegan.In 1994,the total outputvalue of light industry wasRMB490.2 billion,and theexport volume of lightindustrial products wasUS＄35.6 billion,one third ofChina’s total export volume.In the first half of 1995,thetotal output value of lightindustry increased 14.7%,andthe export volume of lightindustrial products wasUS＄18.9 billion,43% over thesame period of 1994.展开更多
文摘It is well known that calcium channel blockers(CCBs) are the first line of therapy for vasospastic angina(VSA). Here, we report two cases of VSA with an increase in the frequency of angina attacks after switching from a brand-name to a generic CCB. In both cases, angina recurred upon switching from a brand-name CCB to a generic CCB during follow-up. The patients' condition improved upon switching back to the original CCB. Both cases involved a high severity of VSA, based on the results of spasm provocation testing. These findings suggest that, in some patients with severe VSA, the frequency of angina attacks increases when switching from a brand-name CCB to a generic CCB. Cardiologists should consider this factor when prescribing drugs for angina.
文摘China’s light industry hasdeveloped rapidly since thereform and opening drivebegan.In 1994,the total outputvalue of light industry wasRMB490.2 billion,and theexport volume of lightindustrial products wasUS＄35.6 billion,one third ofChina’s total export volume.In the first half of 1995,thetotal output value of lightindustry increased 14.7%,andthe export volume of lightindustrial products wasUS＄18.9 billion,43% over thesame period of 1994.
