Pica is an eating disorder in which non-nutritional objects are frequently eaten, and may have serious side effects for both the mother and neonate. The aim of this study was to determine the pica and its association ...Pica is an eating disorder in which non-nutritional objects are frequently eaten, and may have serious side effects for both the mother and neonate. The aim of this study was to determine the pica and its association with biochemical profiles of pregnant women and its relation to pregnancy outcome. A prospective cohort study was conducted in five health care centers in Zahedan City, Iran, in 2011-2012. Samples of pregnant women (n = 200) in the age groups 18 - 40 years were selected for this study and interviewed using a questionnaire. Maternal biochemical profiles (hemoglobin and ferritin) during pregnancy, mean gestational age and pregnancy outcome namely height, weight, and head circumferences of neonates were compared to pregnant women who reported pica (pica group) and women who did not (without pica group). The results showed pica prevalence categorized by substance as follows: clay (23.3%), ice (53.7%), ice and freezer frost (11.5%) and other substances (11.5%). Women in pica group had lower hemoglobin levels during the three trimesters of pregnancy than without pica group. Head circumferences of neonates in pica groups were significantly lower than those of without pica groups (31.0 ± 0.6 vs. 34.0 ± 0.2 respectively). There were no differences in mean birth weight, length, gestational age of infants born to pregnant women from the pica group and without pica group. The findings suggest that the pica practices during pregnancy are associated with lower maternal hemoglobin during the?pregnancy periods, and also significantly lower head circumferences of neonates. Dietitians should ask pregnant women with anemia about pica and should counsel pregnant women who report pica.展开更多
[Objectives]To explore the efficacy of Danshen Injection combined with phosphocreatine disodium in treating frequent premature contractions during pregnancy and its effect on maternal and infant outcomes.[Methods]A to...[Objectives]To explore the efficacy of Danshen Injection combined with phosphocreatine disodium in treating frequent premature contractions during pregnancy and its effect on maternal and infant outcomes.[Methods]A total of 200 pregnant women with normal pregnancy and frequent premature contractions who were treated in the outpatient department of internal medicine in Women and Children's Hospital of Hubei Province and Xinzhou District People's Hospital of Wuhan Central Hospital during September 2015 and October 2018 were selected and randomly divided into the control group and observation group,100 cases for each group.The observation group was treated with Danshen Injection combined with phosphocreatine disodium,and the control group was treated with phosphocreatine disodium alone.The course of treatment in both groups was one week.During the treatment,the changes of heart rate,heart rhythm,electrocardiogram and 24-h dynamic electrocardiogram(DCG)of both groups were observed.[Results]After treatment,the clinical efficacy of the observation group was better than that of the control group,and the difference was statistically significant(P<0.01).There were no adverse drug reactions in both groups.However,in the control group,non-sustained ventricular tachycardia(NSVT)was found in 24-h dynamic electrocardiogram(DCG)of 2 pregnant women with premature ventricular contraction.The pregnancy process was smooth,with full-term natural delivery and no fetal malformation.There was no significant difference in gestational age and neonatal weight between the two groups(P>0.05).However,there was a statistically significant difference in Apgar score between the two groups(P<0.05).During the 6-month postpartum follow-up,the mother and child were unharmed,and examination of repeated electrocardiograms showed that the conditions were normal.[Conclusions]Danshen Injection combined with phosphocreatine disodium has better efficacy in the treatment of frequent premature contractions during pregnancy and the maternal and infant outcomes than the treatment with phosphocreatine disodium alone,and it has good safety and can prevent premature contractions from progressing to tachyarrhythmias.展开更多
慢性乙型肝炎(chronic hepatitis B,CHB)是全球性的公共卫生问题,我国是CHB危害最为严重的国家之一。母婴传播是乙肝病毒(hepatitis B virus,HBV)感染的重要途径,治疗和阻断孕期HBV传播是降低HBV感染及CHB患病率的重要手段。本文从妊娠...慢性乙型肝炎(chronic hepatitis B,CHB)是全球性的公共卫生问题,我国是CHB危害最为严重的国家之一。母婴传播是乙肝病毒(hepatitis B virus,HBV)感染的重要途径,治疗和阻断孕期HBV传播是降低HBV感染及CHB患病率的重要手段。本文从妊娠期CHB的治疗现状入手,综述了国内外妊娠期CHB抗病毒治疗药物、治疗病毒载量阈值及治疗时机选择,并对妊娠期CHB的治疗新希望提出展望。展开更多
文摘Pica is an eating disorder in which non-nutritional objects are frequently eaten, and may have serious side effects for both the mother and neonate. The aim of this study was to determine the pica and its association with biochemical profiles of pregnant women and its relation to pregnancy outcome. A prospective cohort study was conducted in five health care centers in Zahedan City, Iran, in 2011-2012. Samples of pregnant women (n = 200) in the age groups 18 - 40 years were selected for this study and interviewed using a questionnaire. Maternal biochemical profiles (hemoglobin and ferritin) during pregnancy, mean gestational age and pregnancy outcome namely height, weight, and head circumferences of neonates were compared to pregnant women who reported pica (pica group) and women who did not (without pica group). The results showed pica prevalence categorized by substance as follows: clay (23.3%), ice (53.7%), ice and freezer frost (11.5%) and other substances (11.5%). Women in pica group had lower hemoglobin levels during the three trimesters of pregnancy than without pica group. Head circumferences of neonates in pica groups were significantly lower than those of without pica groups (31.0 ± 0.6 vs. 34.0 ± 0.2 respectively). There were no differences in mean birth weight, length, gestational age of infants born to pregnant women from the pica group and without pica group. The findings suggest that the pica practices during pregnancy are associated with lower maternal hemoglobin during the?pregnancy periods, and also significantly lower head circumferences of neonates. Dietitians should ask pregnant women with anemia about pica and should counsel pregnant women who report pica.
基金the Project of National Natural Science Foundation of China(81370337&81970331).
文摘[Objectives]To explore the efficacy of Danshen Injection combined with phosphocreatine disodium in treating frequent premature contractions during pregnancy and its effect on maternal and infant outcomes.[Methods]A total of 200 pregnant women with normal pregnancy and frequent premature contractions who were treated in the outpatient department of internal medicine in Women and Children's Hospital of Hubei Province and Xinzhou District People's Hospital of Wuhan Central Hospital during September 2015 and October 2018 were selected and randomly divided into the control group and observation group,100 cases for each group.The observation group was treated with Danshen Injection combined with phosphocreatine disodium,and the control group was treated with phosphocreatine disodium alone.The course of treatment in both groups was one week.During the treatment,the changes of heart rate,heart rhythm,electrocardiogram and 24-h dynamic electrocardiogram(DCG)of both groups were observed.[Results]After treatment,the clinical efficacy of the observation group was better than that of the control group,and the difference was statistically significant(P<0.01).There were no adverse drug reactions in both groups.However,in the control group,non-sustained ventricular tachycardia(NSVT)was found in 24-h dynamic electrocardiogram(DCG)of 2 pregnant women with premature ventricular contraction.The pregnancy process was smooth,with full-term natural delivery and no fetal malformation.There was no significant difference in gestational age and neonatal weight between the two groups(P>0.05).However,there was a statistically significant difference in Apgar score between the two groups(P<0.05).During the 6-month postpartum follow-up,the mother and child were unharmed,and examination of repeated electrocardiograms showed that the conditions were normal.[Conclusions]Danshen Injection combined with phosphocreatine disodium has better efficacy in the treatment of frequent premature contractions during pregnancy and the maternal and infant outcomes than the treatment with phosphocreatine disodium alone,and it has good safety and can prevent premature contractions from progressing to tachyarrhythmias.
文摘慢性乙型肝炎(chronic hepatitis B,CHB)是全球性的公共卫生问题,我国是CHB危害最为严重的国家之一。母婴传播是乙肝病毒(hepatitis B virus,HBV)感染的重要途径,治疗和阻断孕期HBV传播是降低HBV感染及CHB患病率的重要手段。本文从妊娠期CHB的治疗现状入手,综述了国内外妊娠期CHB抗病毒治疗药物、治疗病毒载量阈值及治疗时机选择,并对妊娠期CHB的治疗新希望提出展望。
