Gas hydrate drilling expeditions in the Pearl River Mouth Basin,South China Sea,have identified concentrated gas hydrates with variable thickness.Moreover,free gas and the coexistence of gas hydrate and free gas have ...Gas hydrate drilling expeditions in the Pearl River Mouth Basin,South China Sea,have identified concentrated gas hydrates with variable thickness.Moreover,free gas and the coexistence of gas hydrate and free gas have been confirmed by logging,coring,and production tests in the foraminifera-rich silty sediments with complex bottom-simulating reflectors(BSRs).The broad-band processing is conducted on conventional three-dimensional(3D)seismic data to improve the image and detection accuracy of gas hydratebearing layers and delineate the saturation and thickness of gas hydrate-and free gas-bearing sediments.Several geophysical attributes extracted along the base of the gas hydrate stability zone are used to demonstrate the variable distribution and the controlling factors for the differential enrichment of gas hydrate.The inverted gas hydrate saturation at the production zone is over 40% with a thickness of 90 m,showing the interbedded distribution with different boundaries between gas hydrate-and free gas-bearing layers.However,the gas hydrate saturation value at the adjacent canyon is 70%,with 30-m-thick patches and linear features.The lithological and fault controls on gas hydrate and free gas distributions are demonstrated by tracing each gas hydrate-bearing layer.Moreover,the BSR depths based on broad-band reprocessed 3D seismic data not only exhibit variations due to small-scale topographic changes caused by seafloor sedimentation and erosion but also show the upward shift of BSR and the blocky distribution of the coexistence of gas hydrate and free gas in the Pearl River Mouth Basin.展开更多
目的探究老年糖尿病治疗中采用甘精胰岛素联合阿卡波糖的价值。方法选取上海市嘉定区迎园医院于2022年6月—2023年9月收治的106例糖尿病老年患者作为研究对象,按随机数表法分为对照组(53例,给予阿卡波糖治疗)、观察组(53例,给予甘精胰...目的探究老年糖尿病治疗中采用甘精胰岛素联合阿卡波糖的价值。方法选取上海市嘉定区迎园医院于2022年6月—2023年9月收治的106例糖尿病老年患者作为研究对象,按随机数表法分为对照组(53例,给予阿卡波糖治疗)、观察组(53例,给予甘精胰岛素联合阿卡波糖治疗)。比较两组临床疗效、血糖指标、体质指数(Body Mass Index,BMI)、不良反应发生情况以及胰岛功能。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组空腹血糖(Fasting Blood Glucose,FBG)、餐后2 h血糖(2 Hour Post⁃prandial Blood Glucose,2 hBG)以及糖化血红蛋白(Hemoglobin A1c,HbA1c)均低于对照组,差异有统计学意义(P均<0.05);观察组体质指数高于对照组,差异有统计学意义(P<0.05);观察组不良反应总发生率与对照组比较,差异无统计学意义(P>0.05);观察组胰岛素抵抗指数(Homeostatic Model Assessment of Insulin Resis⁃tance,HOMA-IR)低于对照组,胰岛β细胞功能指数(Homeostasis Model Assessment-β,HOMA-β)高于对照组,差异有统计学意义(P均<0.05)。结论在老年糖尿病治疗中选择甘精胰岛素与阿卡波糖联合方案可降低血糖水平,改善体质指数及胰岛素功能,确保治疗有效性。展开更多
基金supported by the State Key Laboratory of Natural Gas Hydrate(No.2022-KFJJ-SHW)the National Natural Science Foundation of China(No.42376058)+2 种基金the International Science&Technology Cooperation Program of China(No.2023YFE0119900)the Hainan Province Key Research and Development Project(No.ZDYF2024GXJS002)the Research Start-Up Funds of Zhufeng Scholars Program.
文摘Gas hydrate drilling expeditions in the Pearl River Mouth Basin,South China Sea,have identified concentrated gas hydrates with variable thickness.Moreover,free gas and the coexistence of gas hydrate and free gas have been confirmed by logging,coring,and production tests in the foraminifera-rich silty sediments with complex bottom-simulating reflectors(BSRs).The broad-band processing is conducted on conventional three-dimensional(3D)seismic data to improve the image and detection accuracy of gas hydratebearing layers and delineate the saturation and thickness of gas hydrate-and free gas-bearing sediments.Several geophysical attributes extracted along the base of the gas hydrate stability zone are used to demonstrate the variable distribution and the controlling factors for the differential enrichment of gas hydrate.The inverted gas hydrate saturation at the production zone is over 40% with a thickness of 90 m,showing the interbedded distribution with different boundaries between gas hydrate-and free gas-bearing layers.However,the gas hydrate saturation value at the adjacent canyon is 70%,with 30-m-thick patches and linear features.The lithological and fault controls on gas hydrate and free gas distributions are demonstrated by tracing each gas hydrate-bearing layer.Moreover,the BSR depths based on broad-band reprocessed 3D seismic data not only exhibit variations due to small-scale topographic changes caused by seafloor sedimentation and erosion but also show the upward shift of BSR and the blocky distribution of the coexistence of gas hydrate and free gas in the Pearl River Mouth Basin.
文摘目的探究老年糖尿病治疗中采用甘精胰岛素联合阿卡波糖的价值。方法选取上海市嘉定区迎园医院于2022年6月—2023年9月收治的106例糖尿病老年患者作为研究对象,按随机数表法分为对照组(53例,给予阿卡波糖治疗)、观察组(53例,给予甘精胰岛素联合阿卡波糖治疗)。比较两组临床疗效、血糖指标、体质指数(Body Mass Index,BMI)、不良反应发生情况以及胰岛功能。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组空腹血糖(Fasting Blood Glucose,FBG)、餐后2 h血糖(2 Hour Post⁃prandial Blood Glucose,2 hBG)以及糖化血红蛋白(Hemoglobin A1c,HbA1c)均低于对照组,差异有统计学意义(P均<0.05);观察组体质指数高于对照组,差异有统计学意义(P<0.05);观察组不良反应总发生率与对照组比较,差异无统计学意义(P>0.05);观察组胰岛素抵抗指数(Homeostatic Model Assessment of Insulin Resis⁃tance,HOMA-IR)低于对照组,胰岛β细胞功能指数(Homeostasis Model Assessment-β,HOMA-β)高于对照组,差异有统计学意义(P均<0.05)。结论在老年糖尿病治疗中选择甘精胰岛素与阿卡波糖联合方案可降低血糖水平,改善体质指数及胰岛素功能,确保治疗有效性。