COVID-19 case fatality risk by age and gender in a high testing setting in Latin America: Chile, March-August 2020

Background:Early severity estimates of coronavirus disease 2019(COVID-19)are critically needed to assess the potential impact of the on going pandemic in differe nt demographic groups.Here we estimate the real-time delayadjusted case fatality rate across nine age groups by gender in Chile,the country with the highest testing rate for COVID-19 in Latin America.Methods:We used a publicly available real-time daily series of age-stratified COVID-19 cases and deaths reported by the Ministry of Health in Chile from the beginning of the epidemic in March through August 31,2020.We used a robust likelihood function and a delay distribution to estimate real-time delay-adjusted case-fatality risk and estimate model parameters using a Monte Carlo Markov Chain in a Bayesian framework.

Age-specific heterogeneity of genetic susceptibility to cardiovascular disease might have opposite outcomes depending on the presence of prediabetes

Examining age-specific heterogeneity of susceptibility to cardiovascular disease is also essential in individuals without prediabetes to determine its relative size and direction compared to those with prediabetes.Of particular interest,age-specific heterogeneity in genetic susceptibility may exhibit opposite directions depending on the presence or absence of prediabetes.

The Dutch, The World Tallest Are Shrinking in the Latest Decade or So: The Lessons from the Case of South Korea and Japan in North-East Asia

The Dutch have been the world tallest since the 1980s but plateaued in height for the past few decades. A century and a half ago, young men at 20 in the Netherlands were 165 cm in mean height, as tall as men in France and Portugal. They grew to 178 cm, as tall as Norwegian in 1960, and 183 cm in mean height in the 1990s and levelled off. It is most likely that the Dutch may have nearly attained genetic potential as a human being. The statue is a net measure that captures the supply of inputs to health. Based on the changes in per capita supply of protein from animal products, FAOSTAT, the Dutch seem to have reached the highest level in per capita supply of animal protein. Increases in the supply of protein, however, do not result in increasing human height, if consumption of other “essential nutrients” is insufficient (Blum, 2013;Mori, 2018)[1][2]. With the close case studies of Japan and South Korea in respect of food consumption specifically by children in growing ages, the author suspects that children in the Netherlands may have been insufficient in the supply of vegetables, “essential nutrients” on the top of animal products.