Inorganic nanoparticles were used to treat cancer cells us well as normal cells. Ca9Sr（ PO4）6（OH）2 nanopartides were prepared through homogeneous precipitation method. Strontium hydroxide, calcium hydroxide solat...Inorganic nanoparticles were used to treat cancer cells us well as normal cells. Ca9Sr（ PO4）6（OH）2 nanopartides were prepared through homogeneous precipitation method. Strontium hydroxide, calcium hydroxide solation and monocalcium phosphate were used as initial materials. The strontium-doped hydroxyapatite nanoparticles were characterized by XRD, PCS and AFM. The nanoparticles were applied to interact with human bepatocellular carcinoma cells Bel-7402 and nornud liver cells L-02. Experimental results revealed that nano strontium-strontium apatiw has different bioeffects on proliferation of these two kinds of cells.展开更多
Subject Code:H16With the support by the National Natural Science Foundation of China,a collaborative study by the research groups led by Prof.Xiao Zhixiong(肖智雄)from the College of Life Science,Sichuan University de...Subject Code:H16With the support by the National Natural Science Foundation of China,a collaborative study by the research groups led by Prof.Xiao Zhixiong(肖智雄)from the College of Life Science,Sichuan University demonstrates thatΔNp63αis a common inhibitory target in oncogenic PI3K/Ras/Her2-induced展开更多
AngiotensinⅡis known as a key biologically active peptide in rennin-angiotensin system, which regulates blood pressure, and angiotensinⅡtype 1 receptor (AT1R) antagonists are widely used as antihypertensive drugs. S...AngiotensinⅡis known as a key biologically active peptide in rennin-angiotensin system, which regulates blood pressure, and angiotensinⅡtype 1 receptor (AT1R) antagonists are widely used as antihypertensive drugs. Since several human cancers have been reported to express AT1R, it is worthwhile to test whether AT1R antagonists展开更多
文摘Inorganic nanoparticles were used to treat cancer cells us well as normal cells. Ca9Sr（ PO4）6（OH）2 nanopartides were prepared through homogeneous precipitation method. Strontium hydroxide, calcium hydroxide solation and monocalcium phosphate were used as initial materials. The strontium-doped hydroxyapatite nanoparticles were characterized by XRD, PCS and AFM. The nanoparticles were applied to interact with human bepatocellular carcinoma cells Bel-7402 and nornud liver cells L-02. Experimental results revealed that nano strontium-strontium apatiw has different bioeffects on proliferation of these two kinds of cells.
文摘Subject Code:H16With the support by the National Natural Science Foundation of China,a collaborative study by the research groups led by Prof.Xiao Zhixiong(肖智雄)from the College of Life Science,Sichuan University demonstrates thatΔNp63αis a common inhibitory target in oncogenic PI3K/Ras/Her2-induced
文摘AngiotensinⅡis known as a key biologically active peptide in rennin-angiotensin system, which regulates blood pressure, and angiotensinⅡtype 1 receptor (AT1R) antagonists are widely used as antihypertensive drugs. Since several human cancers have been reported to express AT1R, it is worthwhile to test whether AT1R antagonists
