A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs...A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs F as a catalyst in the reaction of malononitrile and aryl aldehydes or isatins with 1,3-cyclohexanediones. The major advantages of this methodology are excellent yield at ambient temperature, very short reaction time（5–10 min）, and use of an inexpensive catalyst.展开更多
Cyclic oligomers of phenolphthalein polyarylene ether sulfone(ketone) were prepared through cyclo-depolymerisation of corresponding polymers using CsF as the catalyst in dipolar aprotic solvent DMAc and DMF, and a fam...Cyclic oligomers of phenolphthalein polyarylene ether sulfone(ketone) were prepared through cyclo-depolymerisation of corresponding polymers using CsF as the catalyst in dipolar aprotic solvent DMAc and DMF, and a family of macrocycles containing from dimer up to at least heptamer were confirmed by GPC, HPLC and MALDI-TOF-MS. The yields of cyclics get as high as 86.3% and 87.9% respectively.展开更多
A mild, efficient and high yielding protocol for the synthesis of 2,2＇-arylmethelene dicyclohexane- 1,3-dione derivatives at room temperature and 9-aryl-1,8-dihydrooctahydroxanthene at conventional heating using cesi...A mild, efficient and high yielding protocol for the synthesis of 2,2＇-arylmethelene dicyclohexane- 1,3-dione derivatives at room temperature and 9-aryl-1,8-dihydrooctahydroxanthene at conventional heating using cesium fluoride as a catalyst is reported. The major advantages of this reaction are excellent yield, very short reaction time and use of inexpensive catalyst.展开更多
基金SAIF Panjab University for providing analytical facilities for characterization of compounds
文摘A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs F as a catalyst in the reaction of malononitrile and aryl aldehydes or isatins with 1,3-cyclohexanediones. The major advantages of this methodology are excellent yield at ambient temperature, very short reaction time（5–10 min）, and use of an inexpensive catalyst.
文摘Cyclic oligomers of phenolphthalein polyarylene ether sulfone(ketone) were prepared through cyclo-depolymerisation of corresponding polymers using CsF as the catalyst in dipolar aprotic solvent DMAc and DMF, and a family of macrocycles containing from dimer up to at least heptamer were confirmed by GPC, HPLC and MALDI-TOF-MS. The yields of cyclics get as high as 86.3% and 87.9% respectively.
文摘A mild, efficient and high yielding protocol for the synthesis of 2,2＇-arylmethelene dicyclohexane- 1,3-dione derivatives at room temperature and 9-aryl-1,8-dihydrooctahydroxanthene at conventional heating using cesium fluoride as a catalyst is reported. The major advantages of this reaction are excellent yield, very short reaction time and use of inexpensive catalyst.
