Treatment of Retinal Vein Obstruction with Acupuncture and Chinese Medicinal Herbs

We have treated thirty-two cases (52 eyes) of retinal vein obstruction by acupuncture and oral administration of Huo Xue Ming Mu Decoction. The total effective rate of 90.38% demonstrated that the treatment was definitely effective.

Traditional Chinese Medicinal Syndromes and Treatment in Colorectal Cancer

Colorectal cancer remains the third most common malignancy worldwide. According to the principles of Traditional Chinese Medicine (TCM), colorectal cancer is related to spleen-deficiency, damp-heat, and toxicity accumulation. Traditional Chinese medicine has been confirmed to effectively reduce toxic side effects and enhance curative effects of chemotherapy, palliate clinical syndrome, prevent recurrence and metastasis, improve quality of life and immune function, and prolong survival time in colorectal cancer. However, TCM theoretical and syndrome differentiation study has lagged far behind due to progression of therapy model in colorectal cancer. As a type of drug treatment, there are some common biological basis between chemotherapy, targeted therapy and anti-cancer herb therapy in colorectal cancer, such as apoptosis, cell senescence and autophagy. There are growing needs to explore the effect mechanism and compatibility of anti-cancer herbs, to further enhance the efficacy of TCM treatment in colorectal cancer.

China Association of Chinese Medicine Paper notice for seminar on clinical application of TCM classic prescriptions and herbs in the treatment of emotional diseases

Hosted by ChinaAssociation of Chinese Medicine,and organized by World Journal of Integrated traditional and western Medicine,seminar on clinical application of TCM classic prescriptions and herbs in the treatment of emotional diseaseis planned to be held in Yichang,Hubei province from June 22nd to 24th.

Effects of Integrated Chinese Herbs and Western Medicine on Swine Toxoplasmosis

[ Objective] To evaluate the efficacy of integrated Chinese herbs and western medicine on the treatment of swine toxoplasmosis, in order to increase cure rate and lower recurrence rate. [ Method] Pigs artificially infected by Toxoplasma gondii were treated with compound suffonamide and a self-designed Chinese herbs formula, and the quantities of toxoplasma in ascites were determined. Animal regression experiment was per- formed after mice were inoculated with pathological samples of the pigs infected with toxoplasma. After treatment with integrated Chinese herbs and western medicine, the clinical manifestations of pigs were observed and the level of circulating antigen （CAg） in sera was detected. Curative effect indexes of integrated Chinese herbs and western medicine-treated group were compared with that of Chinese herbs-treated group, western medi- cine-treated group and positive control group. [ Result] All the toxoplasma trophozoites were killed by integrated and westem medicine. Regression expedment results showed that toxoplasma appeared only in one mouse that was inoculated with brain of pig. The treated pigs had nonsignificant clinical symptoms; the peak of serum CAg was lower than that of the positive control group and CAg turned negative faster than that of Chinese herbs-treated group, westem medicine-treated group, and positive control group. [ Conclusion] The integrated Chinese herbs and western medicine has good effect on the treatment of swine toxoplasmosis.

Traditional Chinese medicine for prevention and treatment of hepatocarcinoma: From bench to bedside

Traditional Chinese medicine(TCM) has played a positive role in the management of hepatocarcinoma. Hepatocarcinoma patients may present Qi-stagnation, damp-heat, blood stasis, Qi-deficiency, Yin-deficiency and other TCM syndromes(Zheng). Modern treatments such as surgery, transarterial chemoembolization(TACE) and high intensity focus ultrasound treatment would influence the manifestation of TCM syndromes. Herbs with traditional efficacy of tonifying Qi, blood and Yin, soothing liver-Qi stagnation, clearing heat and detoxifying and dissolving stasis, have been demonstrated to be potent to prevent hepatocarcinogenesis. TCM has been widely used in all aspects of integrative therapy in hepatocarcinoma, including surgical resection, liver transplantation, TACE, local ablative therapies and even as monotherapy for middle-advanced stage hepatocarcinoma. Clinical practices have confirmed that TCM is effective to alleviate clinical symptoms, improve quality of life and immune function, prevent recurrence and metastasis, delay tumor progression, and prolong survival time in hepatocarcinoma patients. The effective mechanism of TCM against hepatocarcinoma is related to inducing apoptosis, autophagy, anoikis and cell senescence, arresting cell cycle, regulating immune function, inhibiting metastasis and angiogenesis, reversing drug resistance and enhancing effects of chemotherapy. Along with the progress of research in this field, TCM will contribute more to the prevention and treatment of hepatocarcinoma.

Overview of the phytomedicine approaches against Helicobacter pylori

Helicobacter pylori(H.pylori)successfully colonizes thehuman stomach of the majority of the human popula-tion.This infection always causes chronic gastritis,butmay evolve to serious outcomes,such as peptic ulcer,gastric carcinoma or mucosa-associated lymphoid tis-sue lymphoma.H.pylori first line therapy recommend-ed by the Maastricht-4 Consensus Report comprises theuse of two antibiotics and a proton-pomp inhibitor,butin some regions failure associated with this treatmentis already undesirable high.Indeed,treatment failure isone of the major problems associated with H.pylori in-fection and is mainly associated with bacterial antibioticresistance.In order to counteract this situation,someeffort has been allocated during the last years in theinvestigation of therapeutic alternatives beyond antibi-otics.These include vaccines,probiotics,photodynamic inactivation and phage therapy,which are briefly revis-ited in this review.A particular focus on phytomedicine,also described as herbal therapy and botanical therapy,which consists in the use of plant extracts for medicinal purposes,is specifically addressed,namely considering its history,category of performed studies,tested com-pounds,active principle and mode of action.The herbs already experienced are highly diverse and usually selected from products with a long history of employ-ment against diseases associated with H.pylori infec-tion from each country own folk medicine.The studies demonstrated that many phytomedicine products have an anti-H.pylori activity and gastroprotective action.Al-though the mechanism of action is far from being com-pletely understood,current knowledge correlates the beneficial action of herbs with inhibition of essential H.pylori enzymes,modulation of the host immune system and with attenuation of inflammation.

CLINICAL OBSERVATION ON COMBINED TREATMENT OF 360 CASES OF PROSTATITIS WITH ACUPUNCTURE OF SISHENCHONG POINT, ETC. AND SELF-DRAFTED PRESCRIPTION I, II AND III

In the present series of observations, 360 cases of prostatitis were treated with acupuncture of Sishenchong (EX HN 1), etc. and self drafted prescription I, II and III. After 4 courses (28 sessions) of treatment, 321 cases (89.17%) were cured, 35 cases (9.72%) had improvement and 4 cases (1.11%) failed. The total effective rate was 98.89%.

新型特色水药罐的设计和应用

目的:研制一种新型特色水药罐,以提高水药罐的操作便利性、密封性、保温性及牢固性。方法:新型特色水药罐材质为树脂类,由双层保温罐体、单向排气阀、调节开关、活塞、风琴软管和弹簧组成。其中双层保温罐体的罐壁为内部中空的双层结构;调节开关的中部设有长方形滑动孔;活塞由活塞杆、尾座和活塞头组成;弹簧位于开关底座旁,上端和调节开关连接,下端和双层保温罐体连接。结果:相较于传统特色水药罐,新型特色水药罐用于拔罐所需时间更短,药液洒漏量更少,拔罐前后药液温差更小。结论:新型特色水药罐临床操作简便、密封性强、保温性能良好、不易破碎,是一种适合临床推广使用的拔罐器具。

国医大师雷忠义运用角药治疗心衰经验探析

心衰是多种心脏疾病发展的终末阶段,是目前心血管常见疾病之一。雷忠义国医大师认为心衰的病机为气虚阳微,血瘀水停,角药是方剂的基本单位,相互配伍,可起到相辅相成、相互制约、减毒增效的作用。雷大师临证常用角药治疗心血管疾病,本文通过论述雷忠义国医大师运用黄芪-人参-制附子、茯苓-桂枝-白术、鹿角胶-龟甲-前胡、玉竹-淫羊藿-制附子、丹参-三七-陈皮、泽兰-益母草-茯苓、葶苈子-小叶萆薢-北五加皮、赤芍-车前子-泽泻八组角药治疗心衰的组成功效、配伍要点、适应症、随证加减等,探析雷大师临证运用角药治疗心衰之经验,以指导专科诊疗,从而提升疗效。

中医外治法治疗膝关节滑膜炎研究进展

膝关节滑膜炎是指膝关节因急性创伤或慢性劳损引起的滑膜无菌性炎症反应,临床症状为膝关节肿胀、疼痛伴活动受限。中医外治法在治疗膝关节滑膜炎的临床应用中具有疗效确切、副作用小、患者依从性高等优点。通过查阅近5年采用中医外治法治疗膝关节滑膜炎的相关文献资料,对中药外敷、中药塌渍、中药熏蒸、针刺疗法、推拿手法等治疗膝关节滑膜炎的临床疗效进行探讨与归纳总结,以期为寻求高效、可行的膝关节滑膜炎中医外治临床诊疗方案提供参考。

Patterns of Herbal Combination for the Treatment of Insomnia Commonly Employed by Highly Experienced Chinese Medicine Physicians

Objective：To explore the most effective herbal combinations commonly used by highly experienced Chinese medicine（CM） physicians for the treatment of insomnia.Methods：We collected and analyzed data related to insomnia treatment from the clinics of 7 highly experienced CM physicians in Beijing.The sample included 162 patients and 460 consultations in total.Patient outcomes,such as sleep quality and sleep time per day,were manually collected from the medical records by trained CM clinicians.Three data mining methods,support vector machine（SVM）,logistic regression and decision tree,and multifactor dimensionality reduction（MDR）,were used to determine and confirm the herbal combinations that resulted in positive outcomes in patients suffering from insomnia.Results：Results show that MDR is the most efficient method to predict the effective herbal combinations.Using the MDR model,we identified several combinations of herbs with 100%positive outcomes,such as stir-fried spine date seed,Szechwan lovage rhizome,and prepared thinleaf milkwort root;white peony root,golden thread,and stir-fried spine date seed;and Asiatic cornelian cherry fruit with fresh rehmannia.Conclusions：Results indicate that herbal combinations are effective treatments for patients with insomnia compared with individual herbs.It is also shown that MDR is a potent data mining method to identify the herbal combination with high rates of positive outcome.

《清宫医案集成》中熏洗方运用初探

[目的]探究《清宫医案集成》中熏洗方治疗疾病的特殊性和有效性,为现代临床外治法提供参考。[方法]以《清宫医案集成》中117首熏洗方为研究对象,运用Excel软件,对清宫熏洗方的组成、剂量、药性、功效进行整理统计,并结合该书中的相关医案及按语,对熏洗方在清宫中的特色运用进行系统整理。[结果]《清宫医案集成》中的117首宫廷熏洗方在遣方用药上展现出种类繁多、质量上乘,方简药精、效专力宏,随证加减、用药灵活,治病为先、不拘药量,善用风药、不避毒药等多种特色;且另有受众广泛、方式独特、器具考究、药液制备过程细致等其他优势。[结论]《清宫医案集成》中的熏洗方颇具宫廷特色及优势,对其运用展开探索能够获得独特的见解和启示,有助于发扬宫廷用药特色,促进中医药外治疗法的发展,具有较高的研究价值。

中医外治法在儿童髋关节一过性滑膜炎的临床应用

目的观察中医外治法在儿童髋关节一过性滑膜炎的临床疗效。方法收集2019年10月1日到2023年10月1日期间在长春市儿童医院住院治疗的髋关节一过性滑膜炎患儿病案资料,对其临床数据进行回顾性分析。结果在相同住院时间内,中医外治组治愈率(42%)高于常规治疗组(19%),比较差异具有统计学意义。结论中医外治法治疗儿童髋关节一过性滑膜炎疗效确切。

中医药防治原发性骨质疏松症专家共识(2015)

中国老年学学会骨质疏松委员会中医药与骨病学科组在前期原发性骨质疏松症临床实践指南和专家共识的基础上,检索和评价相关文献资料,通过临床医师的问卷调查和学科组讨论,结合临床实际情况,并咨询我国中医骨伤科界名老专家意见,制定本共识,旨在为中医学或中西医结合医学专业医师提供参考。共识提出:根据原发性骨质疏松症的中医病因病机,辨证分为肾阳虚证、肝肾阴虚证、脾肾阳虚证、肾虚血瘀证、脾胃虚弱证和血瘀气滞证,明确相应治法和中药方剂;原则是"辨证施治,整体调节,防治结合",合理选择治疗方案、观察指标和检测项目,关注长期用药的安全性,以及临床疗效评价与监测;并强调预防原发性骨质疏松症"未病先防、既病防变、瘥后防复"的原则与方法,充分发挥中医学的特色和优势。

血必净注射液对重症创伤患者炎症反应的抑制作用

目的探讨早期应用血必净注射液对重症创伤患者炎症反应的影响和临床应用价值。方法采用前瞻性研究方法，选择2009年10月至2010年11月急诊重症监护病房（EIcu）收治的重症创伤患者93例，按随机原则分为治疗组（45例）和对照组（48例）；两组患者一般处理及对症治疗方法相同，治疗组加用血必净注射液100ml静脉滴注，12h1次，连用7d；观察患者病死率、EICU住院时间、体温、白细胞计数（WBC）、氧合指数（PaO2／FiO2）、外周血管阻力指数（SVRI）、血乳酸的变化；采酶联免疫吸附法（ELISA）检测血中肿瘤坏死因子-α（TNF—α）含量的变化。结果治疗组和对照组治疗后病死率和EICU住院时间比较差异均无统计学意义[病死率：30．8％比32．6％；EICU住院时间（d）：9．5±2．5比11．3±2．1，均P〉0．053；体温、WBC、血乳酸、TNF—α均较治疗前明显降低，PaO2／FiO2、SVRI均较治疗前明显升高，且治疗组降低和升高程度较对照组更显著[体温（℃）：37．4v10．5比38．5±11．6；WBC（×10^9／L）：10．6±5．5比13．5±6．7；乳酸（mmol／L）：1．28±0．44比1．54±0．58；TNF—α（ng／L）：18．1±5．8比27．9±9．5；PaO2／FiO2（mmHg，1mmHg=0．133kPa）：286．3±55．3比229．3±55．2；SVRI（kPa·s·L^-1：211．7±28．9比198．0±25．8，P〈0．05或P〈0．01]。结论早期应用血必净注射液能有效抑制重症创伤患者的炎症反应，改善血流动力学状况，纠正脓毒性休克症状，减少EICU住院时间和病死率。

中药防治鸡球虫病的研究进展

从中药防治鸡球虫病的特点、防治效果和抗球虫病中药制剂的毒性以及使用中药防治鸡球虫病存在的问题等方面综述了中草药及其复方制剂在抗鸡球虫病方面的研究进展。

中西药结合对猪弓形虫病的疗效研究

[目的]评价中西药结合治疗猪弓形虫病的疗效,以提高其治愈率、降低复发率。[方法]用复方磺胺类药结合自拟抗弓形虫中药方剂对人工感染弓形虫病的猪进行治疗,检测其腹水含虫量。将感染猪病料接种小白鼠,进行动物回归试验。观察中西药结合治疗猪的临床表现并检测其血清循环抗原(CAg)水平,与中药组、西药组和对照组进行比较。[结果]中西药结合对弓形虫滋养体有100%杀灭作用。回归试验结果表明仅有1只接种脑组织的小白鼠中发现少量弓形虫。治疗猪只均未出现明显临床症状,其血清CAg峰值低于对照组且转阴速度比中药组、西药组和对照组快。[结论]中西药结合治疗猪弓形虫病具有较好的疗效。

针刺推拿配合中药治疗海洛因成瘾临床疗效观察

目的:探讨针刺推拿配合中药综合治疗海洛因成瘾临床疗效及应用价值。方法:采用随机方法将符合DSM-Ⅲ-R阿片类诊断标准的109例海洛因依赖者分为单纯服用中药排毒养生胶囊组(单药组)和服用排毒养生胶囊联合针刺与推拿治疗组(针药组);使用阿片类戒断综合征量表(OWS)评测两组对海洛因成瘾戒断综合征治疗效果;用操守随访调查表评测近期(3个月)巩固操守率。结果:12 d治疗观察结果显示:单药组和针药组临床脱毒率均为100%,但针药组脱毒达标时间为d3,单药组为d4;戒断症状分项比较结果:针药组对腹痛、肌骨疼痛、失眠主显症状控制效果明显优于单药组;近期巩固操守率:针药组为37.5%,单药组为28.5%,两组有统计学差异(P<0.05)。结论:针刺推拿配合中药戒毒,可提高海洛因成瘾戒断综合征控制水平和近期操守率。

中草药对硒性白内障防治作用的研究

用亚硒酸钠诱发大鼠产生白内障,同时用中药予以防治,发现方剂6号和方剂7号对硒性白内障具有显著的防治效应,且能拮抗硒引起的晶体内一些生化变化。方剂6号和方剂7号可望成为治疗人类早期白内障的有效药物。

中草药治疗输卵管阻塞性不孕的系统评价

目的 评价中草药治疗输卵管阻塞性不孕的疗效与安全性。 方法 通过检索MEDLINE、EMBASE、CBM及Cochrane临床试验数据库及手工检索所提取文献的参考文献 ,比较中草药 (包括单剂和复合剂 )与安慰剂、未治疗、手术或常规西药治疗的随机对照试验 ,并用Cochrane协作网专用软件Revman 4 2进行Meta 分析。 结果 有 7篇随机对照试验共治疗 10 4 2名病人 (平均每篇 14 8例 )满足纳入标准。与常规西药抗炎、通水治疗相比 ,活血化瘀之中草药的输卵管复通效果优于西药抗炎通水法 [RR 1 4 9,95 %CI(1 37,1 6 2 ) ,P <0 0 0 0 0 1],妊娠率亦高于西药抗炎通水法 [RR 1 4 6 ,95 %CI(1 0 9,1 96 ) ,P =0 0 1],且中草药治疗组未见不良反应。 结论 现有临床资料表明 ,中草药治疗输卵管阻塞性不孕可能有效 ,但由于试验在严格随机、双盲、严格随访等方面还有欠缺 ,其疗效目前尚无充分的证据。在以后的研究中尚需要设计良好的随机、双盲、安慰剂对照试验对其潜在的疗效加以证实。