Correlation between blood glucose fluctuations and activation of oxidative stress in type 1 diabetic children during the acute metabolic disturbance period

Background Studies have shown that complications in type 1 diabetes mellitus （T1DM） in children are mainly due to oxidative stress （OS）. Lipid peroxidation is the main marker of OS and iso-prostaglandin is a reliable biomarker of lipid peroxidation in type 2 diabetes mellitus （T2DM）. However, there have been few studies on OS in T1DM children with hyperglycemia and glucose fluctuations.