A facile method for the synthesis of a new series of R,R-2-（4-（2-（4-（5-chloro-3-halopyridin-2-yloxy）-phenoxy）-propionyloxy）-phenoxy） -propionic acid ester derivatives containing a halo-substituted pyridine car...A facile method for the synthesis of a new series of R,R-2-（4-（2-（4-（5-chloro-3-halopyridin-2-yloxy）-phenoxy）-propionyloxy）-phenoxy） -propionic acid ester derivatives containing a halo-substituted pyridine carrying two R,R chiral centers from（R）-2-（4- hydroxyphenoxy）propionic acid,halopyridines and alcohols using base/cyanuric chloride/catalyst system is reported.Their herbicidal activities against grass weeds and crops selectivity were evaluated.展开更多
Imazethapyr(IM)is a widely used acetolactate synthase-inhibiting chiral herbicide.It has long-term residuals that may be absorbed by the human body through the edible parts of plants,such as vegetable leaves or fruits...Imazethapyr(IM)is a widely used acetolactate synthase-inhibiting chiral herbicide.It has long-term residuals that may be absorbed by the human body through the edible parts of plants,such as vegetable leaves or fruits.Here,we selected a model plant,Arabidopsis thaliana,to determine the effects of R-IM and S-IM on its leaf structure,photosynthetic efficiency,and metabolites,as well as the structures of microorganisms in the phyllosphere,after 7 days of exposure.Our results indicated enantiomeric differences in plant growth between R-IM and S-IM;133μg/kg R-IM showed heavier inhibition of photosynthetic efficiency and greater changes to subcellular structure than S-IM.R-IM and S-IM also had different effects on metabolism and leaf microorganisms.S-IM mainly increased lipid compounds and decreased amino acids,while R-IM increased sugar accumulation.The relative abundance of Moraxellaceae human pathogenic bacteria was increased by R-IM treatment,indicating that R-IM treatment may increase leaf surface pathogenic bacteria.Our research provides a new perspective for evaluating the harmfulness of pesticide residues in soil,phyllosphere microbiome changes via the regulation of plant metabolism,and induced pathogenic bacterial accumulation risks.展开更多
文摘A facile method for the synthesis of a new series of R,R-2-（4-（2-（4-（5-chloro-3-halopyridin-2-yloxy）-phenoxy）-propionyloxy）-phenoxy） -propionic acid ester derivatives containing a halo-substituted pyridine carrying two R,R chiral centers from（R）-2-（4- hydroxyphenoxy）propionic acid,halopyridines and alcohols using base/cyanuric chloride/catalyst system is reported.Their herbicidal activities against grass weeds and crops selectivity were evaluated.
基金supported by the National Natural Science Foundation of China(Nos.21777144,21976161)the CAS Pioneer Hundred Talents Program(H.F.Qian)the Xinjiang Uighur Autonomous Region Talent Project(H.F.Qian)。
文摘Imazethapyr(IM)is a widely used acetolactate synthase-inhibiting chiral herbicide.It has long-term residuals that may be absorbed by the human body through the edible parts of plants,such as vegetable leaves or fruits.Here,we selected a model plant,Arabidopsis thaliana,to determine the effects of R-IM and S-IM on its leaf structure,photosynthetic efficiency,and metabolites,as well as the structures of microorganisms in the phyllosphere,after 7 days of exposure.Our results indicated enantiomeric differences in plant growth between R-IM and S-IM;133μg/kg R-IM showed heavier inhibition of photosynthetic efficiency and greater changes to subcellular structure than S-IM.R-IM and S-IM also had different effects on metabolism and leaf microorganisms.S-IM mainly increased lipid compounds and decreased amino acids,while R-IM increased sugar accumulation.The relative abundance of Moraxellaceae human pathogenic bacteria was increased by R-IM treatment,indicating that R-IM treatment may increase leaf surface pathogenic bacteria.Our research provides a new perspective for evaluating the harmfulness of pesticide residues in soil,phyllosphere microbiome changes via the regulation of plant metabolism,and induced pathogenic bacterial accumulation risks.
