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Analysis of Protein-Ligand Interactions of SARS-CoV-2 Against Selective Drug Using Deep Neural Networks 被引量:1
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作者 Natarajan Yuvaraj Kannan Srihari +3 位作者 Selvaraj Chandragandhi Rajan Arshath Raja Gaurav Dhiman Amandeep Kaur 《Big Data Mining and Analytics》 EI 2021年第2期76-83,共8页
In recent time, data analysis using machine learning accelerates optimized solutions on clinical healthcare systems. The machine learning methods greatly offer an efficient prediction ability in diagnosis system alter... In recent time, data analysis using machine learning accelerates optimized solutions on clinical healthcare systems. The machine learning methods greatly offer an efficient prediction ability in diagnosis system alternative with the clinicians. Most of the systems operate on the extracted features from the patients and most of the predicted cases are accurate. However, in recent time, the prevalence of COVID-19 has emerged the global healthcare industry to find a new drug that suppresses the pandemic outbreak. In this paper, we design a Deep Neural Network(DNN)model that accurately finds the protein-ligand interactions with the drug used. The DNN senses the response of protein-ligand interactions for a specific drug and identifies which drug makes the interaction that combats effectively the virus. With limited genome sequence of Indian patients submitted to the GISAID database, we find that the DNN system is effective in identifying the protein-ligand interactions for a specific drug. 展开更多
关键词 Deep Neural Network(DNN) CORONAVIRUS protein-ligand interactions deep learning clinical healthcare system
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