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Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury
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作者 Mou Gao Qin Dong +3 位作者 Dan Zou Zhijun Yang Lili Guo Ruxiang Xu 《Neural Regeneration Research》 SCIE CAS 2025年第5期1416-1430,共15页
Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and repair.We previously reported that induced neural stem cells ... Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and repair.We previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological recovery.However,the mechanism of CXCR4 upregulation in induced neural stem cells remains unclear.In this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 expression.However,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial activation.In agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury mice.Notably,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head injury.In conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neural stem cells on microglial activation via upregulation of CXCR4 and Crry,thereby promoting induced neural stem cell–mediated improvement of neuronal injury,cerebral edema,and neurological disorders following closed head injury. 展开更多
关键词 Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell MICROGLIA NEUROINFLAMMATION
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Simulation Modelling and Techno-Economics of Supercritical Carbon Dioxide Recompression Closed Brayton Cycle
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作者 Ken Amaale Atinga 《Energy and Power Engineering》 2024年第10期325-344,共20页
In recent years, there has been global interest in meeting targets relating to energy affordability and security while taking into account greenhouse gas emissions. This has heightened major interest in potential inve... In recent years, there has been global interest in meeting targets relating to energy affordability and security while taking into account greenhouse gas emissions. This has heightened major interest in potential investigations into the use of supercritical carbon dioxide (sCO2) power cycles. Climate change mitigation is the ultimate driver for this increased interest;other relevant issues include the potential for high cycle efficiency and a circular economy. In this study, a 25 MWe recompression closed Brayton cycle (RCBC) has been assessed, and sCO2 has been proposed as the working fluid for the power plant. The methodology used in this research work comprises thermodynamic and techno-economic analysis for the prospective commercialization of this sCO2 power cycle. An evaluated estimation of capital expenditure, operational expenditure, and cost of electricity has been considered in this study. The ASPEN Plus simulation results have been compared with theoretical and mathematical calculations to assess the performance of the compressors, turbine, and heat exchangers. The results thus reveal that the cycle efficiency for this prospective sCO2 recompression closed Brayton cycle increases (39% - 53.6%) as the temperature progressively increases from 550˚C to 900˚C. Data from the Aspen simulation model was used to aid the cost function calculations to estimate the total capital investment cost of the plant. Also, the techno-economic results have shown less cost for purchasing equipment due to fewer components being required for the cycle configuration as compared to the conventional steam power plant. 展开更多
关键词 Supercritical Carbon Dioxide (sCO2) closed Brayton Cycle TECHNO-ECONOMICS Simulation Capital Expenditure Gas Turbine THERMODYNAMIC Equipment Cost Optimization and Sensitivity
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Long non-coding RNA H19 regulates neurogenesis of induced neural stem cells in a mouse model of closed head injury 被引量:3
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作者 Mou Gao Qin Dong +4 位作者 Zhijun Yang Dan Zou Yajuan Han Zhanfeng Chen Ruxiang Xu 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第4期872-880,共9页
Stem cell-based therapies have been proposed as a potential treatment for neural regeneration following closed head injury.We previously reported that induced neural stem cells exert beneficial effects on neural regen... Stem cell-based therapies have been proposed as a potential treatment for neural regeneration following closed head injury.We previously reported that induced neural stem cells exert beneficial effects on neural regeneration via cell replacement.However,the neural regeneration efficiency of induced neural stem cells remains limited.In this study,we explored differentially expressed genes and long non-coding RNAs to clarify the mechanism underlying the neurogenesis of induced neural stem cells.We found that H19 was the most downregulated neurogenesis-associated lnc RNA in induced neural stem cells compared with induced pluripotent stem cells.Additionally,we demonstrated that H19 levels in induced neural stem cells were markedly lower than those in induced pluripotent stem cells and were substantially higher than those in induced neural stem cell-derived neurons.We predicted the target genes of H19 and discovered that H19 directly interacts with mi R-325-3p,which directly interacts with Ctbp2 in induced pluripotent stem cells and induced neural stem cells.Silencing H19 or Ctbp2 impaired induced neural stem cell proliferation,and mi R-325-3p suppression restored the effect of H19 inhibition but not the effect of Ctbp2 inhibition.Furthermore,H19 silencing substantially promoted the neural differentiation of induced neural stem cells and did not induce apoptosis of induced neural stem cells.Notably,silencing H19 in induced neural stem cell grafts markedly accelerated the neurological recovery of closed head injury mice.Our results reveal that H19 regulates the neurogenesis of induced neural stem cells.H19 inhibition may promote the neural differentiation of induced neural stem cells,which is closely associated with neurological recovery following closed head injury. 展开更多
关键词 closed head injury Ctbp2 induced neural stem cell lncRNA H19 miR-325-3p NEUROGENESIS
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Design and analysis of an advanced thermal management system for the solar close observations and proximity experiments spacecraft 被引量:1
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作者 Liu Liu Kangli Bao +4 位作者 Jianchao Feng Xiaofei Zhu Haoyu Wang Xiaofeng Zhang Jun Lin 《Astronomical Techniques and Instruments》 CSCD 2024年第1期52-61,共10页
In this paper,the mission and the thermal environment of the Solar Close Observations and Proximity Experiments(SCOPE)spacecraft are analyzed,and an advanced thermal management system(ATMS)is designed for it.The relat... In this paper,the mission and the thermal environment of the Solar Close Observations and Proximity Experiments(SCOPE)spacecraft are analyzed,and an advanced thermal management system(ATMS)is designed for it.The relationship and functions of the integrated database,the intelligent thermal control system and the efficient liquid cooling system in the ATMS are elaborated upon.For the complex thermal field regulation system and extreme space thermal environment,a modular simulation and thermal field planning method are proposed,and the feasibility of the planning algorithm is verified by numerical simulation.A solar array liquid cooling system is developed,and the system simulation results indicate that the temperatures of the solar arrays meet the requirements as the spacecraft flies by perihelion and aphelion.The advanced thermal management study supports the development of the SCOPE program and provides a reference for the thermal management in other deep-space exploration programs. 展开更多
关键词 Solar close Observations and Proximity Experiments Adaptive thermal control method Thermal field planning method Pumped liquid cooling system Advanced thermal management system
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Research on perturbation of neutron fluence rate in a closed thermal neutron field due to medium materials
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作者 Jun-Kai Yang Ping-Quan Wang +8 位作者 Zhi-Meng Hu Fan Li Jun-Mei Zeng Lin Xiao Hong-Yu Guo Jian Zhang Giuseppe Gorini Hui Zhang Chungming Paul Chu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第10期222-232,共11页
The neutron radiation field has vital applications in areas such as biomedicine,geology,radiation safety,and many others for neutron detection and neutron metrology.Correcting neutron fluence rate perturbation accurat... The neutron radiation field has vital applications in areas such as biomedicine,geology,radiation safety,and many others for neutron detection and neutron metrology.Correcting neutron fluence rate perturbation accurately is an important yet challenging problem.This study proposes a correction method that analyzes three physical processes.This method,which transforms the detection process from point detection to area detection,is based on a novel physical model and has been validated through theoretical analyses,experiments,and simulations.According to the average differences between the calculated and experimental results,the new method(1.67%)demonstrated better accuracy than the traditional simulation(2.17%).In a closed thermal neutron radiation field,the detector or strong neutron absorption material significantly perturbs the neutron fluence rate,whereas its impact on the energy spectrum shape and neutron directionality is relatively minor.Furthermore,based on the calculation results of the perturbation rate formula for medium materials with different compositions and sizes,the larger the volume and capture cross section of the medium,the higher the perturbation rate generated in the closed radiation field. 展开更多
关键词 Perturbation rate Area detection Three-dimensional neutron energy spectrum closed radiation field
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Formation of a Rapidly Rotating Classical Be-star in a Massive Close Binary System
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作者 Evgeny Staritsin 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2024年第1期44-50,共7页
This paper investigates the spin-up of a mass-accreting star in a close binary system passing through the first stage of mass exchange in the Hertzsprung gap. Inside an accreting star, angular momentum is carried by m... This paper investigates the spin-up of a mass-accreting star in a close binary system passing through the first stage of mass exchange in the Hertzsprung gap. Inside an accreting star, angular momentum is carried by meridional circulation and shear turbulence. The circulation carries part of the angular momentum of the accreted layers to the accretor's surface. The greater the rate of arrival of angular momentum in the accretor is, the greater this part. It is assumed that this part of the angular momentum can be removed by the disk further from the accretor. If the angular momentum in the matter entering the accretor is more than half the Keplerian value, then the angular momentum obtained by the accretor during mass exchange stage does not depend on the rate of arrival of angular momentum. The accretor may have the characteristics of a Be-star immediately after the end of mass exchange. 展开更多
关键词 (stars:)binaries(including multiple):close stars:emission-line BE stars:early-type stars:rotation
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Sensing-Communication-Computing-Control Closed Loop for NOMA-UAV Systems
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作者 Lei Chengleyang Feng Wei +4 位作者 Wang Jue Wang Yanmin Jin Shi Yin Liuguo Ge Ning 《China Communications》 SCIE CSCD 2024年第8期89-103,共15页
In the areas without terrestrial communication infrastructures,unmanned aerial vehicles(UAVs)can be utilized to serve field robots for mission-critical tasks.For this purpose,UAVs can be equipped with sensing,communic... In the areas without terrestrial communication infrastructures,unmanned aerial vehicles(UAVs)can be utilized to serve field robots for mission-critical tasks.For this purpose,UAVs can be equipped with sensing,communication,and computing modules to support various requirements of robots.In the task process,different modules assist the robots to perform tasks in a closed-loop way,which is referred to as a sensing-communication-computing-control(SC3)loop.In this work,we investigate a UAV-aided system containing multiple SC^(3)loops,which leverages non-orthogonal multiple access(NOMA)for efficient resource sharing.We describe and compare three different modelling levels for the SC^(3)loop.Based on the entropy SC^(3)loop model,a sum linear quadratic regulator(LQR)control cost minimization problem is formulated by optimizing the communication power.Further for the assure-to-be-stable case,we show that the original problem can be approximated by a modified user fairness problem,and accordingly gain more insights into the optimal solutions.Simulation results demonstrate the performance gain of using NOMA in such task-oriented systems,as well as the superiority of our proposed closed-loop-oriented design. 展开更多
关键词 closed loop linear quadratic regulator(LQR) non-orthogonal multiple access(NOMA) power allocation unmanned aerial vehicle(UAV)
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Point-symmetry in SNR G1.9+0.3:A Supernova that Destroyed its Planetary Nebula Progenitor
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作者 Noam Soker 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2024年第1期165-172,共8页
I analyze a new X-ray image of the youngest supernova remnant(SNR)in the Galaxy,which is the type Ia SNR G1.9+0.3,and reveal a very clear point-symmetrical structure.Since explosion models of type Ia supernovae(SNe Ia... I analyze a new X-ray image of the youngest supernova remnant(SNR)in the Galaxy,which is the type Ia SNR G1.9+0.3,and reveal a very clear point-symmetrical structure.Since explosion models of type Ia supernovae(SNe Ia)do not form such morphologies,the point-symmetrical morphology must come from the circumstellar material(CSM)into which the ejecta expands.The large-scale point-symmetry that I identify and the known substantial deceleration of the ejecta of SNR G1.9+0.3 suggest a relatively massive CSM of■1M⊙.I argue that the most likely explanation is the explosion of this SN Ia into a planetary nebula.The scenario that predicts a large fraction of SN Ia inside PNe(SNIPs)is the core degenerate scenario.Other SN Ia scenarios might lead to only a very small fraction of SNIPs or none at all. 展开更多
关键词 (stars:)supernovae:general ISM:supernova remnants (stars:)binaries(including multiple):close (ISM:)planetary nebulae:general stars:jets
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Design and Test of Closed Hydraulic Transmission System of 4WD High-clearance Wheeled Sprayer
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作者 Hengfeng CHEN Xiaobo XU 《Plant Diseases and Pests》 2024年第3期14-20,共7页
In conjunction with the working characteristics of the high-clearance wheeled sprayer and the benefits of the closed hydraulic system,a series of reasonable working parameters should be established,and a hydraulic sys... In conjunction with the working characteristics of the high-clearance wheeled sprayer and the benefits of the closed hydraulic system,a series of reasonable working parameters should be established,and a hydraulic system that fulfills the requisite specifications should be designed.The AMESim software model is employed to construct a closed hydraulic transmission system,and the simulation analysis is then performed according to the data of hydraulic components.According to analysis results,the prototype can be optimized and upgraded,and a verification test is further carried out.The test results demonstrate that the designed closed hydraulic transmission system meets the actual working requirements of the high-clearance wheeled sprayer and provides a stable experimental platform for intelligent control of agricultural machinery. 展开更多
关键词 closed hydraulic transmission system High-clearance Wheeled sprayer Modeling and simulation Verification test
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Discussion on Dust Removal(Suppression)System of Crushing Station in Open-Pit Coal Mine
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作者 Hong ZHANG Lin LIN Bo CAO 《Asian Agricultural Research》 2024年第2期18-21,共4页
This paper introduces the method of coal dust treatment in crushing station and the present situation of dust removal system in typical open-pit coal mine crushing station in China,and expounds the research idea of de... This paper introduces the method of coal dust treatment in crushing station and the present situation of dust removal system in typical open-pit coal mine crushing station in China,and expounds the research idea of determining comprehensive dust removal(suppression)system in crushing station inspired by the working principle of"range hood".Based on the design example and link optimization of the crush-ing station of open-pit coal mine I of Thar coalfield,this paper finally draws some conclusions on the key technologies of dust removal(suppression)system of open-pit coal mine crushing station.This study has certain reference value for the technical innovation of dust removal(suppression)system in crushing station,the realization of green mining in"crushing link",and the reduction and avoidance of ecological environment pollution in mining area. 展开更多
关键词 Crushing station closed dust cover Wind curtain wall Air volume simulation Dust suppression by spraying
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Factors Associated with Closely Spaced Pregnancies at the Departmental Hospital Centre of Zou-Collines (Benin) in 2022
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作者 Klikpezo Roger Hounkponou Nouéssewa Fanny Maryline +7 位作者 Atade Sèdjro Raoul Agbegbanou Eudoxie Ahouingnan Yeyinou Salifou Badaryatou Dettin Eric Obossou Achilles Imorou Sidi Salifou Kabibou 《Open Journal of Obstetrics and Gynecology》 2024年第1期89-101,共13页
Introduction: Birth spacing to prevent closely-spaced pregnancies, which are a source of maternal and neonatal morbidity and mortality, is not always respected by our women, as recommended by the World Health Organiza... Introduction: Birth spacing to prevent closely-spaced pregnancies, which are a source of maternal and neonatal morbidity and mortality, is not always respected by our women, as recommended by the World Health Organization (WHO). The objective was to study the factors associated with closely-spaced pregnancies among women followed at the Departmental Hospital Center du Zou et du Colline (DHC/Z-C) in 2022. Study Method: This was a descriptive, analytical cross-sectional study with prospective data collection from 20 May to 30 June 2022. Results: At the end of the study, 83 of the 117 women surveyed had close pregnancies, a frequency of 70.94%. They had an average age of 27.0 ± 6.3 years and were of Fon ethnicity and related in 91.57% of cases. The majority were married (96.60%). The factors significantly associated with these closely spaced pregnancies were age between 25 and 30 years, household occupation, age at first birth, age at marriage, women’s perception of contraceptive method (CM), women’s knowledge of the existence of a center providing family planning services and non-use of MC. Conclusion: Close pregnancies are still very common in the commune of Abomey. It is therefore important to increase the use of contraceptive methods in this part of the country. 展开更多
关键词 close Pregnancy Associated Factors DHC/Z-C
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On Fuzzy Regularly Closed Filters in Michálek Fuzzy Topological Space
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作者 Puthenpurackal Ratnakumar Neethu Bloomy Joseph 《Advances in Pure Mathematics》 2024年第10期779-784,共6页
C.L. Chang’s introduction of fuzzy topology in 1981 opened up new avenues for parallel theories in topology. However, Chang’s work appears to focus more on the topology of fuzzy sets rather than fuzzy topology itsel... C.L. Chang’s introduction of fuzzy topology in 1981 opened up new avenues for parallel theories in topology. However, Chang’s work appears to focus more on the topology of fuzzy sets rather than fuzzy topology itself. In 1975, Michálek presented a functional definition of ordinary topology and later developed fuzzy topology as a distinct extension of this idea, setting it apart from Chang’s approach. While there has been significant research on Chang’s fuzzy topology, Michálek’s version has not received as much attention. This paper introduces the concept of fuzzy regularly closed filters, or FRCM filters, within Michálek’s fuzzy topological space and explores some properties of FRCM ultrafilters. 展开更多
关键词 TOPOLOGY Fuzzy Topology Michálek’s Fuzzy Topological Space Fuzzy closed Fuzzy Open FILTERS
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An Explanation of the Temperature-Dependent Upper Critical Field Data of H3S on the Basis of the Thermodynamics of a Superconductor in a Magnetic Field
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作者 Gulshan Prakash Malik 《World Journal of Condensed Matter Physics》 CAS 2024年第3期45-50,共6页
Excellent fits to a couple of the data-sets on the temperature (T)-dependent upper critical field (Hc2) of H3S (critical temperature, Tc ≈ 200 K at pressure ≈ 150 GPa) reported by Mozaffari, et al. (2019) were obtai... Excellent fits to a couple of the data-sets on the temperature (T)-dependent upper critical field (Hc2) of H3S (critical temperature, Tc ≈ 200 K at pressure ≈ 150 GPa) reported by Mozaffari, et al. (2019) were obtained by Talantsev (2019) in an approach based on an ingenious mix of the Ginzberg-Landau (GL), the Werthamer, Helfand and Hohenberg (WHH), and the Gor’kov, etc., theories which have individually been employed for the same purpose for a long time. Up to the lowest temperature (TL) in each of these data-sets, similarly accurate fits have also been obtained by Malik and Varma (2023) in a radically different approach based on the Bethe-Salpeter equation (BSE) supplemented by the Matsubara and the Landau quantization prescriptions. For T TL, however, while the (GL, WHH, etc.)-based approach leads to Hc2(0) ≈ 100 T, the BSE-based approach leads to about twice this value even at 1 K. In this paper, a fit to one of the said data-sets is obtained for the first time via a thermodynamic approach which, up to TL, is as good as those obtained via the earlier approaches. While this is interesting per se, another significant result of this paper is that for T TL it corroborates the result of the BSE-based approach. 展开更多
关键词 H3S upper Critical Field (Hc2) Variation of Hc2 with Temperature Clausius-Clapeyron equation in a magnetic field Behavior of Hc2 for Temperatures close to 0 K
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Study on the Effect of Behavioral Interventions Based on the Theory of“Knowledge,Attitude,Practice”on Tuberculosis Cognitive Level of Close Contacts
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作者 Beiyan Zhang Yifei Hu +2 位作者 Jun Ji Donghui Hao Xuehui Jiao 《Journal of Clinical and Nursing Research》 2024年第2期123-128,共6页
Objective:Based on the theory of“Knowledge,Attitude,Practice,”health education was carried out for close contact with tuberculosis(TB)at a university in Beijing,and its impact on the students’awareness of TB was st... Objective:Based on the theory of“Knowledge,Attitude,Practice,”health education was carried out for close contact with tuberculosis(TB)at a university in Beijing,and its impact on the students’awareness of TB was studied.This study could provide a reference for effective health education interventions among close contacts of TB in undergraduates.Methods:102 undergraduates who had close contact with one confirmed case of pulmonary TB in April 2021 at a university were randomly divided into a control group and an intervention group.The intervention group was given the“Knowledge,Attitude,Practice”health education intervention by professionally trained doctors,and were asked to complete a self-designed TB-related questionnaire before and after the intervention.Both groups performed the Tuberculin Skin Test(TST)and chest X-ray(CR)examination.Results:The rate of the TST test was 18.6%,and CR examination showed 0 cases of pulmonary TB.The survey results showed that the TB awareness rate(96.1%,49/51)in the intervention group was significantly higher than that of the control group(51.0%,26/51),and the differences in awareness rate between the two groups were statistically significant(P<0.05).Regarding the attitude/skills toward TB,the prevalence rate of tuberculosis-related attitude/behavior in the intervention group(94.1%,47/51)was significantly higher than that of the control group(60.8%,31/51),and the differences between the two groups were statistically significant(P<0.05).Conclusion:Both self-controlled and parallel-controlled studies showed that the health education intervention of“Knowledge,Attitude,Practice”improved the awareness of TB among close contacts of TB in undergraduates. 展开更多
关键词 UNDERGRADUATES close contact of tuberculosis Behavioral intervention Health education
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The Moon in Close Up
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作者 TANG YUANKAI 《Beijing Review》 2010年第29期42-43,共2页
Chinese scientists have designed lunar rovers, and plan to land one on the Moon in 201 3 Anifty gold-colored vehicle equipped with two solar panel wings
关键词 The Moon in close up
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Mechanical model for controlling floor heave in deep roadways with U-shaped steel closed support 被引量:5
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作者 Zhao Yiming Liu Na +1 位作者 Zheng Xigui Zhang Nong 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2015年第5期713-720,共8页
Open U-shaped steel arch supports are commonly used in large-section static-pressure roadways in coal mines that are more than 900 m deep;however,it is very difficult to control floor heave of roadways.In this paper,a... Open U-shaped steel arch supports are commonly used in large-section static-pressure roadways in coal mines that are more than 900 m deep;however,it is very difficult to control floor heave of roadways.In this paper,a U-shaped steel closed support with an inverted U-shaped steel arch in the floor is proposed as a method for improving the support effect of the surrounding rock during the process of floor heaving.This research established a mechanical model for the U-shaped steel closed support,and determined the reaction forces at the connection of a camber angle.Using the limit load method calculated the critical buckling load of the inverted U-shaped steel arch,and use of a strength check method tested the strength of the U-shaped steel material.A numerical simulation was conducted using the finite difference software FLAC3 D.The simulation results show that the U-shaped steel closed support is able to control the floor heave of roadways,which is successfully used in the West 11-2 development roadway of the Zhuji Mine in the Huainan mining area in China.The cumulative floor heave over two years was less than50 mm. 展开更多
关键词 U-shaped steel closed support Deep roadway Floor heave FLAC3D
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Pressure Buildup Analysis for a Well in a Closed, Bounded Multiwell Reservoir 被引量:2
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作者 林加恩 杨慧珠 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2005年第4期441-450,共10页
A general method has been developed for analyzing pressure buildup data from a well located in a system with both production and injection wells in a closed, bounded two-phase flow reservoir. The proposed method enabl... A general method has been developed for analyzing pressure buildup data from a well located in a system with both production and injection wells in a closed, bounded two-phase flow reservoir. The proposed method enables one to calculate the total mobility or permeability-thickness product, the skin factor, the average drainage-area pressure and the injection-production ratio (at the instant of shut-in) with accuracy from pressure buildup (or falloff) data dominated by a linear trend of reservoir pressure. Out of thousands of well tests, several typical field examples have been presented to illustrate the application of the proposed method for analyzing pressure transient data from a well located in a water-injection multiwell reservoir. And the possible application of this method to heterogeneous systems such as naturally fractured reservoirs is also discussed. Approaches to aid practicing engineers in verifying the buildup interpretation (or recognizing the interference of offset wells) are presented. Extension of the presented method to a gas well located in a multiwell gas reservoir is also suggested 展开更多
关键词 two-phase flow multiwell reservoir well test analysis closed system gas well test
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Operating Analysis of the Closed Supply Chain of Green Agricultural Products Based on Logistics Center 被引量:2
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作者 WANG Duo-hong,LI Yu,ZHAO Hong-xia,ZHANG Jiang-quan Traffic transportation department,Southwest Jiaotong University-E’mei,E’mei 614202,China 《Asian Agricultural Research》 2010年第3期44-50,共7页
This thesis gives the overview of concept and constitution of the closed supply chain of green agricultural products based on logistics center,and the necessity of regarding logistics center as core enterprise.Meanwhi... This thesis gives the overview of concept and constitution of the closed supply chain of green agricultural products based on logistics center,and the necessity of regarding logistics center as core enterprise.Meanwhile,it analyzes the function of logistics center of agricultural products,namely functions of exchange,collection,distribution,storage and transportation.It also poses the prerequisites of logistics center.The logistics center of agricultural products must have stable profit expectancy,prominent scale,strong appealing power,capacity of bearing market risk and basic thoughts of supply chain management.The functional design of the closed supply chain of green agricultural products has been discussed in 5 aspects,namely logistics center,production base,providers of means of production,retailer and consumer.The operating thoughts of the closed supply chain of green agricultural products based on logistics center are put forward on the basis of the research of operating objective and service target of supply chain as follows:first,based on local principal agricultural products,the logistics center mainly distributes the massed agricultural products;second,it is necessary to choose appropriate strategic cooperative partners to sign contract;third,the operating procedure of supply chain entails bringing in professional managerial talents of supply chain;finally,the relationships of supply chain should be maintained. 展开更多
关键词 closeD supply CHAIN Operating MODE LOGISTICS cente
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The determination of 52 elements in marine geological samples by an inductively coupled plasma optical emission spectrometry and an inductively coupled plasma mass spectrometry with a high-pressure closed digestion method 被引量:16
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作者 GAO Jingjing LIU Jihua +3 位作者 LI Xianguo YAN Quanshu WANG Xiaojing WANG Hongmin 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2017年第1期109-117,共9页
An improved analytical method to determine the content of 52 major, minor and trace elements in marine geological samples, using a HF-HCl-HNO_3 acid system with a high-pressure closed digestion method(HPCD), is stud... An improved analytical method to determine the content of 52 major, minor and trace elements in marine geological samples, using a HF-HCl-HNO_3 acid system with a high-pressure closed digestion method(HPCD), is studied by an inductively coupled plasma optical emission spectrometry(ICP-OES) and an inductively coupled plasma mass spectrometry(ICP-MS). The operating parameters of the instruments are optimized, and the optimal analytical parameters are determined. The influences of optical spectrum and mass spectrum interferences, digestion methods and acid systems on the analytical results are investigated. The optimal spectral lines and isotopes are chosen, and internal standard element of rhodium is selected to compensate for matrix effects and analytical signals drifting. Compared with the methods of an electric heating plate digestion and a microwave digestion, a high-pressure closed digestion method is optimized with less acid, complete digestion,less damage for digestion process. The marine geological samples are dissolved completely by a HF-HCl-HNO_3 system, the relative error(RE) for the analytical results are all less than 6.0%. The method detection limits are 2–40μg/g by the ICP-OES, and 6–80 ng/g by ICP-MS. The methods are used to determine the marine sediment reference materials(GBW07309, GBW07311, GBW07313), rock reference materials(GBW07103, GBW07104,GBW07105), and cobalt-rich crust reference materials(GBW07337, GBW07338, GBW07339), the obtained analytical results are in agreement with the certified values, and both of the relative standard deviation(RSD) and the relative error(RE) are less than 6.0%. The analytical method meets the requirements for determining 52 elements contents of bulk marine geological samples. 展开更多
关键词 marine geological sample high-pressure closed digestion method inductively coupled plasma optical emission spectrometry inductively coupled plasma mass spectrometry major element minor element trace element
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Researches on Risk Evaluation of Green Agro-product Closed Supply Chain 被引量:2
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作者 WANG Xue-feng 《Asian Agricultural Research》 2011年第7期85-87,91,共4页
Closed supply chain is a superior form of management model of chain supply and an effective means of improving the modernization of agro-product circulation. Based on the research results of the current literatures on... Closed supply chain is a superior form of management model of chain supply and an effective means of improving the modernization of agro-product circulation. Based on the research results of the current literatures on supply chain risk and agro-product supply chain, related subjects of the agro-product closed supply chain involving production, management and consumption are studied and analyzed and the primary risking factors in the supply chain system are classified as environmental risk, system risk, information risk, management risk and quality risk. Risk of agro-product closed supply chain is evaluated by using the method of fuzzy comprehensive evaluation and the values are acquired. The result shows that risk of agro-product closed supply chain is moderate with relatively high risk, which basically accords with the present actual situations. It can be seen from the index weights of various levels that the key first-level indices influencing the risks are system risk, information risk, quality and safety risk and the key second-level are the coordinating and controlling ability of core enterprises, the implementation of information traceability and the construction of quality safety system. Therefore, risk of agro-product closed supply chain should be reduced by taking prevention and controlling measures mainly from these aspects. 展开更多
关键词 Green agro-products closed supply chain Risk evaluation China
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