This paper is concerned with the Navier-Stokes/Allen-Cahn system,which is used to model the dynamics of immiscible two-phase flows.We consider a 1D free boundary problem and assume that the viscosity coefficient depen...This paper is concerned with the Navier-Stokes/Allen-Cahn system,which is used to model the dynamics of immiscible two-phase flows.We consider a 1D free boundary problem and assume that the viscosity coefficient depends on the density in the form ofη(ρ)=ρ^(α).The existence of unique global H^(2m)-solutions(m∈N)to the free boundary problem is proven for when 0<α<1/4.Furthermore,we obtain the global C^(∞)-solutions if the initial data is smooth.展开更多
This paper studies the(2+1)-dimensional Hirota-Satsuma-Ito equation.Based on an associated Hirota bilinear form,lump-type solution,two types of interaction solutions,and breather wave solution of the(2+1)-dimensional ...This paper studies the(2+1)-dimensional Hirota-Satsuma-Ito equation.Based on an associated Hirota bilinear form,lump-type solution,two types of interaction solutions,and breather wave solution of the(2+1)-dimensional Hirota-Satsuma-Ito equation are obtained,which are all related to the seed solution of the equation.It is interesting that the rogue wave is aroused by the interaction between one-lump soliton and a pair of resonance stripe solitons,and the fusion and fission phenomena are also found in the interaction between lump solitons and one-stripe soliton.Furthermore,the breather wave solution is also obtained by reducing the two-soliton solutions.The trajectory and period of the one-order breather wave are analyzed.The corresponding dynamical characteristics are demonstrated by the graphs.展开更多
In this paper,we consider the semilinear elliptic equation systems{△u+u=αQ_(n)(x)|u|^(α-2)|v|^(β)u in R^(N),-△v+v=βQ(x)|u|^(α)|v|^(β-2)v in R^(N),where N≥3,α,β>1,α+β<2^(*),2^(*)=2N/N-2 and Q_(n) are...In this paper,we consider the semilinear elliptic equation systems{△u+u=αQ_(n)(x)|u|^(α-2)|v|^(β)u in R^(N),-△v+v=βQ(x)|u|^(α)|v|^(β-2)v in R^(N),where N≥3,α,β>1,α+β<2^(*),2^(*)=2N/N-2 and Q_(n) are bounded given functions whose self-focusing cores{x∈R^(N)|Q_(n)(x)>0} shrink to a set with finitely many points as n→∞.Motivated by the work of Fang and Wang[13],we use variational methods to study the limiting profile of ground state solutions which are concentrated at one point of the set with finitely many points,and we build the localized concentrated bound state solutions for the above equation systems.展开更多
This paper is concerned with the following attraction-repulsion chemotaxis system with p-Laplacian diffusion and logistic source:■The system here is under a homogenous Neumann boundary condition in a bounded domainΩ...This paper is concerned with the following attraction-repulsion chemotaxis system with p-Laplacian diffusion and logistic source:■The system here is under a homogenous Neumann boundary condition in a bounded domainΩ ■ R^(n)(n≥2),with χ,ξ,α,β,γ,δ,k_(1),k_(2)> 0,p> 2.In addition,the function f is smooth and satisfies that f(s)≤κ-μs~l for all s≥0,with κ ∈ R,μ> 0,l> 1.It is shown that(ⅰ)if l> max{2k_(1),(2k_(1)n)/(2+n)+1/(p-1)},then system possesses a global bounded weak solution and(ⅱ)if k_(2)> max{2k_(1)-1,(2k_(1)n)/(2+n)+(2-p)/(p-1)} with l> 2,then system possesses a global bounded weak solution.展开更多
A Hamiltonian system is derived for the plane elasticity problem of two-dimensional dodecagonal quasicrystals by introducing the simple state function. By using symplectic elasticity approach, the analytic solutions o...A Hamiltonian system is derived for the plane elasticity problem of two-dimensional dodecagonal quasicrystals by introducing the simple state function. By using symplectic elasticity approach, the analytic solutions of the phonon and phason displacements are obtained further for the quasicrystal plates. In addition, the effectiveness of the approach is verified by comparison with the data of the finite integral transformation method.展开更多
On one hand,we study the existence of transcendental entire solutions with finite order of the Fermat type difference equations.On the other hand,we also investigate the existence and growth of solutions of nonlinear ...On one hand,we study the existence of transcendental entire solutions with finite order of the Fermat type difference equations.On the other hand,we also investigate the existence and growth of solutions of nonlinear differential-difference equations.These results extend and improve some previous in[5,14].展开更多
The phase field method is playing an increasingly important role in understanding and predicting morphological evolution in materials and biological systems.Here,we develop a new analytical approach based on the bifur...The phase field method is playing an increasingly important role in understanding and predicting morphological evolution in materials and biological systems.Here,we develop a new analytical approach based on the bifurcation analysis to explore the mathematical solution structure of phase field models.Revealing such solution structures not only is of great mathematical interest but also may provide guidance to experimentally or computationally uncover new morphological evolution phenomena in materials undergoing electronic and structural phase transitions.To elucidate the idea,we apply this analytical approach to three representative phase field equations:the Allen-Cahn equation,the Cahn-Hilliard equation,and the Allen-Cahn-Ohta-Kawasaki system.The solution structures of these three phase field equations are also verified numerically by the homotopy continuation method.展开更多
Under investigation in this paper is a complex modified Korteweg–de Vries(KdV) equation, which describes the propagation of short pulses in optical fibers. Bilinear forms and multi-soliton solutions are obtained thro...Under investigation in this paper is a complex modified Korteweg–de Vries(KdV) equation, which describes the propagation of short pulses in optical fibers. Bilinear forms and multi-soliton solutions are obtained through the Hirota method and symbolic computation. Breather-like and bound-state solitons are constructed in which the signs of the imaginary parts of the complex wave numbers and the initial separations of the two parallel solitons are important factors for the interaction patterns. The periodic structures and position-induced phase shift of some solutions are introduced.展开更多
We study the global existence and uniqueness of a strong solution to the kinetic thermomechanical Cucker-Smale(for short,TCS) model coupled with Stokes equations in the whole space.The coupled system consists of the k...We study the global existence and uniqueness of a strong solution to the kinetic thermomechanical Cucker-Smale(for short,TCS) model coupled with Stokes equations in the whole space.The coupled system consists of the kinetic TCS equation for a particle ensemble and the Stokes equations for a fluid via a drag force.In this paper,we present a complete analysis of the existence of global-in-time strong solutions to the coupled model without any smallness restrictions on the initial data.展开更多
According to the second law of thermodynamics, as currently understood, any given transit of a system along the reversible path proceeds with a total entropy change equal to zero. The fact that this condition is also ...According to the second law of thermodynamics, as currently understood, any given transit of a system along the reversible path proceeds with a total entropy change equal to zero. The fact that this condition is also the identifier of thermodynamic equilibrium, makes each and every point along the reversible path a state of equilibrium, and the reversible path, as expressed by a noted thermodynamic author, “a dense succession of equilibrium states”. The difficulties with these notions are plural. The fact, for example, that systems need to be forced out of equilibrium via the expenditure of work, would make any spontaneous reversible process a consumer of work, this in opposition to common thermodynamic wisdom that makes spontaneous reversible processes the most efficient transformers of work-producing-potential into actual work. The solution to this and other related impasses is provided by Dialectical Thermodynamics via its previously proved notion assigning a negative entropy change to the energy upgrading process represented by the transformation of heat into work. The said solution is here exemplified with the ideal-gas phase isomerization of butane into isobutane.展开更多
Background:Cancer-related fatigue(CRF)is a common and debilitating symptom experienced by patients with advanced-stage cancer,especially those undergoing antitumor therapy.This study aimed to evaluate the efficacy and...Background:Cancer-related fatigue(CRF)is a common and debilitating symptom experienced by patients with advanced-stage cancer,especially those undergoing antitumor therapy.This study aimed to evaluate the efficacy and safety of Renshenguben(RSGB)oral solution,a ginseng-based traditional Chinese medicine,in alleviating CRF in patients with advanced hepatocellular carcinoma(HCC)receiving antitumor treatment.Methods:In this prospective,open-label,controlled,multicenter study,patients with advanced HCC at BCLC stage C and a brief fatigue inventory(BFI)score of≥4 were enrolled.Participants were assigned to the RSGB group(RSGB,10 mL twice daily)or the control group(with supportive care).Primary and secondary endpoints were the change in multidimensional fatigue inventory(MFI)score,and BFI and functional assessment of cancer therapy-hepatobiliary(FACT-Hep)scores at weeks 4 and 8 after enrollment.Adverse events(AEs)and toxicities were assessed.Results:A total of 409 participants were enrolled,with 206 assigned to the RSGB group.At week 4,there was a trend towards improvement,but the differences were not statistically significant.At week 8,the RSGB group exhibited a significantly lower MFI score(P<0.05)compared to the control group,indicating improved fatigue levels.Additionally,the RSGB group showed significantly greater decrease in BFI and FACT-Hep scores at week 8(P<0.05).Subgroup analyses among patients receiving various antitumor treatments showed similar results.Multivariate linear regression analyses revealed that the RSGB group experienced a significantly substantial decrease in MFI,BFI,and FACT-Hep scores at week 8.No serious drug-related AEs or toxicities were observed.Conclusions:RSGB oral solution effectively reduced CRF in patients with advanced HCC undergoing antitumor therapy over an eight-week period,with no discernible toxicities.These findings support the potential of RSGB oral solution as an adjunctive treatment for managing CRF in this patient population.展开更多
Solid solution-strengthened copper alloys have the advantages of a simple composition and manufacturing process,high mechanical and electrical comprehensive performances,and low cost;thus,they are widely used in high-...Solid solution-strengthened copper alloys have the advantages of a simple composition and manufacturing process,high mechanical and electrical comprehensive performances,and low cost;thus,they are widely used in high-speed rail contact wires,electronic component connectors,and other devices.Overcoming the contradiction between low alloying and high performance is an important challenge in the development of solid solution-strengthened copper alloys.Taking the typical solid solution-strengthened alloy Cu-4Zn-1Sn as the research object,we proposed using the element In to replace Zn and Sn to achieve low alloying in this work.Two new alloys,Cu-1.5Zn-1Sn-0.4In and Cu-1.5Zn-0.9Sn-0.6In,were designed and prepared.The total weight percentage content of alloying elements decreased by 43%and 41%,respectively,while the product of ultimate tensile strength(UTS)and electrical conductivity(EC)of the annealed state increased by 14%and 15%.After cold rolling with a 90%reduction,the UTS of the two new alloys reached 576 and 627MPa,respectively,the EC was 44.9%IACS and 42.0%IACS,and the product of UTS and EC(UTS×EC)was 97%and 99%higher than that of the annealed state alloy.The dislocations proliferated greatly in cold-rolled alloys,and the strengthening effects of dislocations reached 332 and 356 MPa,respectively,which is the main reason for the considerable improvement in mechanical properties.展开更多
In this paper,we establish some regularity conditions on the density and velocity fields to guarantee the energy conservation of the weak solutions for the three-dimensional compressible nematic liquid crystal flow in...In this paper,we establish some regularity conditions on the density and velocity fields to guarantee the energy conservation of the weak solutions for the three-dimensional compressible nematic liquid crystal flow in the periodic domain.展开更多
In this paper,we establish global classical solutions of semilinear wave equations with small compact supported initial data posed on the product space R^(3)×T.The semilinear nonlinearity is assumed to be of the ...In this paper,we establish global classical solutions of semilinear wave equations with small compact supported initial data posed on the product space R^(3)×T.The semilinear nonlinearity is assumed to be of the cubic form.The main ingredient here is the establishment of the L^(2)-L^(∞)decay estimates and the energy estimates for the linear problem,which are adapted to the wave equation on the product space.The proof is based on the Fourier mode decomposition of the solution with respect to the periodic direction,the scaling technique,and the combination of the decay estimates and the energy estimates.展开更多
Based on the Landau-Lifshitz-Gilbert(LLG)equation,the precession relaxation of magnetization is studied when the external field H is parallel to the uniaxial anisotropic field H_(k).The evolution of three-component ma...Based on the Landau-Lifshitz-Gilbert(LLG)equation,the precession relaxation of magnetization is studied when the external field H is parallel to the uniaxial anisotropic field H_(k).The evolution of three-component magnetization is solved analytically under the condition of H=nH_(k)(n=3,1 and 0).It is found that with an increase of H or a decrease of the initial polar angle of magnetization,the relaxation time decreases and the angular frequency of magnetization increases.For comparison,the analytical solution for H_(k)=0 is also given.When the magnetization becomes stable,the angular frequency is proportional to the total effective field acting on the magnetization.The analytical solutions are not only conducive to the understanding of the precession relaxation of magnetization,but also can be used as a standard model to test the numerical calculation of LLG equation.展开更多
The hydrogen absorption/desorption kinetic properties of MgH_(2)can be effectively enhanced by doping specific catalysts.In this work,MOFs-derived NiCu@C nanoparticles(~15 nm)with regular core-shell structure were suc...The hydrogen absorption/desorption kinetic properties of MgH_(2)can be effectively enhanced by doping specific catalysts.In this work,MOFs-derived NiCu@C nanoparticles(~15 nm)with regular core-shell structure were successfully prepared and introduced into MgH_(2)(denoted as MgH_(2)-NiCu@C).The onset and peak temperatures of hydrogen desorption of MgH_(2)-11 wt.%NiCu@C are 175.0℃and282.2℃,respectively.The apparent activation energy of dehydrogenated reaction is 77.2±4.5 kJ/mol for MgH_(2)-11 wt.%NiCu@C,which is lower than half of that of the as-milled MgH_(2).Moreover,MgH_(2)-11 wt.%NiCu@C displays great cyclic stability.The strengthening"hydrogen pumping"effect of reversible solid solutions Mg_(2)Ni(Cu)/Mg_(2)Ni(Cu)H_(4)is proposed to explain the remarkable improvement in hydrogen absorption/desorption kinetic properties of MgH_(2).This work offers a novel perspective for the design of bimetallic nanoparticles and beyond for application in hydrogen storage and other energy related fields.展开更多
Studying the relationship between ionic interactions and salt solubility in seawater has implications for seawater desalination and mineral extraction.In this paper,a new method of expressing ion-to-ion interaction is...Studying the relationship between ionic interactions and salt solubility in seawater has implications for seawater desalination and mineral extraction.In this paper,a new method of expressing ion-to-ion interaction is proposed by using molecular dynamics simulation,and the relationship between ion-to-ion interaction and salt solubility in a simulated seawater water-salt system is investigated.By analyzing the variation of distance and contact time between ions in an electrolyte solution,from both spatial and temporal perspectives,new parameters were proposed to describe the interaction between ions:interaction distance(ID),and interaction time ratio(ITR).The best correlation between characteristic time ratio and solubility was found for a molar ratio of salt-to-water of 10:100 with a correlation coefficient of 0.96.For the same salt,a positive correlation was found between CTR and the molar ratio of salt and water.For type 1-1,type 2-1,type 1-2,and type 2-2 salts,the correlation coefficients between CTR and solubility were 0.93,0.96,0.92,and 0.98 for a salt-to-water molar ratio of 10:100,respectively.The solubility of multiple salts was predicted by simulations and compared with experimental values,yielding an average relative deviation of 12.4%.The new ion-interaction parameters offer significant advantages in describing strongly correlated and strongly hydrated electrolyte solutions.展开更多
This study examined the impact of current solution treatment on the microstructure and mechanical properties of the Co-28Cr-6Mo-0.22C alloy investment castings.The findings reveal that the current solution treatment s...This study examined the impact of current solution treatment on the microstructure and mechanical properties of the Co-28Cr-6Mo-0.22C alloy investment castings.The findings reveal that the current solution treatment significantly promotes the dissolution of carbides at a lower temperature.The optimal conditions for solution treatment are determined as a solution temperature of 1,125°C and a holding time of 5.0 min.Under these parameters,the size and volume fraction of precipitated phases in the investment castings are measured as6.2μm and 1.1vol.%.The yield strength,ultimate tensile strength,and total elongation of the Co-28Cr-6Mo-0.22C investment castings are 535 MPa,760 MPa,and 12.6%,respectively.These values exceed those obtained with the conventional solution treatment at 1,200°C for 4.0 h.The findings suggest a phase transformation of M_(23)C_(6)→σ+C following the current solution treatment at 1,125°C for 5.0 min.In comparison,the traditional solution treatment at 1,200°C for 4.0 h leads to the formation of M_(23)C_(6)and M_(6)C carbides.It is noteworthy that the non-thermal effect of the current during the solution treatment modifies the free energy of both the matrix and precipitation phase.This modification lowers the phase transition temperature of the M_(23)C_(6)→σ+C reaction,thereby facilitating the dissolution of carbides.As a result,the current solution treatment approach achieves carbide dissolution at a lower temperature and within a significantly shorter time when compared to the traditional solution treatment methods.展开更多
In this paper,we are concerned with a three-dimensional non-isothermal model for the compressible nematic liquid crystal flows in a periodic domain.Under some smallness and structural assumptions imposed on the time-p...In this paper,we are concerned with a three-dimensional non-isothermal model for the compressible nematic liquid crystal flows in a periodic domain.Under some smallness and structural assumptions imposed on the time-periodic force,we establish the existence of the time-periodic solutions to the system by using a regularized approximation scheme and the topological degree theory.We also prove a uniqueness result via energy estimates.展开更多
基金supported by the Key Project of the NSFC(12131010)the NSFC(11771155,12271032)+1 种基金the NSF of Guangdong Province(2021A1515010249,2021A1515010303)supported by the NSFC(11971179,12371205)。
文摘This paper is concerned with the Navier-Stokes/Allen-Cahn system,which is used to model the dynamics of immiscible two-phase flows.We consider a 1D free boundary problem and assume that the viscosity coefficient depends on the density in the form ofη(ρ)=ρ^(α).The existence of unique global H^(2m)-solutions(m∈N)to the free boundary problem is proven for when 0<α<1/4.Furthermore,we obtain the global C^(∞)-solutions if the initial data is smooth.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.12275172 and 11905124)。
文摘This paper studies the(2+1)-dimensional Hirota-Satsuma-Ito equation.Based on an associated Hirota bilinear form,lump-type solution,two types of interaction solutions,and breather wave solution of the(2+1)-dimensional Hirota-Satsuma-Ito equation are obtained,which are all related to the seed solution of the equation.It is interesting that the rogue wave is aroused by the interaction between one-lump soliton and a pair of resonance stripe solitons,and the fusion and fission phenomena are also found in the interaction between lump solitons and one-stripe soliton.Furthermore,the breather wave solution is also obtained by reducing the two-soliton solutions.The trajectory and period of the one-order breather wave are analyzed.The corresponding dynamical characteristics are demonstrated by the graphs.
基金supported by the NSFC (12071438)supported by the NSFC (12201232)
文摘In this paper,we consider the semilinear elliptic equation systems{△u+u=αQ_(n)(x)|u|^(α-2)|v|^(β)u in R^(N),-△v+v=βQ(x)|u|^(α)|v|^(β-2)v in R^(N),where N≥3,α,β>1,α+β<2^(*),2^(*)=2N/N-2 and Q_(n) are bounded given functions whose self-focusing cores{x∈R^(N)|Q_(n)(x)>0} shrink to a set with finitely many points as n→∞.Motivated by the work of Fang and Wang[13],we use variational methods to study the limiting profile of ground state solutions which are concentrated at one point of the set with finitely many points,and we build the localized concentrated bound state solutions for the above equation systems.
基金supported by the National Natural Science Foundation of China(12301251,12271232)the Natural Science Foundation of Shandong Province,China(ZR2021QA038)the Scientific Research Foundation of Linyi University,China(LYDX2020BS014)。
文摘This paper is concerned with the following attraction-repulsion chemotaxis system with p-Laplacian diffusion and logistic source:■The system here is under a homogenous Neumann boundary condition in a bounded domainΩ ■ R^(n)(n≥2),with χ,ξ,α,β,γ,δ,k_(1),k_(2)> 0,p> 2.In addition,the function f is smooth and satisfies that f(s)≤κ-μs~l for all s≥0,with κ ∈ R,μ> 0,l> 1.It is shown that(ⅰ)if l> max{2k_(1),(2k_(1)n)/(2+n)+1/(p-1)},then system possesses a global bounded weak solution and(ⅱ)if k_(2)> max{2k_(1)-1,(2k_(1)n)/(2+n)+(2-p)/(p-1)} with l> 2,then system possesses a global bounded weak solution.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.12261064 and 11861048)the Natural Science Foundation of Inner Mongolia,China (Grant Nos.2021MS01004 and 2022QN01008)the High-level Talents Scientific Research Start-up Foundation of Inner Mongolia University (Grant No.10000-21311201/165)。
文摘A Hamiltonian system is derived for the plane elasticity problem of two-dimensional dodecagonal quasicrystals by introducing the simple state function. By using symplectic elasticity approach, the analytic solutions of the phonon and phason displacements are obtained further for the quasicrystal plates. In addition, the effectiveness of the approach is verified by comparison with the data of the finite integral transformation method.
基金Supported by the National Natural Science Foundation of China(12261023,11861023)the Foundation of Science and Technology project of Guizhou Province of China([2018]5769-05)。
文摘On one hand,we study the existence of transcendental entire solutions with finite order of the Fermat type difference equations.On the other hand,we also investigate the existence and growth of solutions of nonlinear differential-difference equations.These results extend and improve some previous in[5,14].
基金supported as part of the Computational Materials Sciences Program funded by the U.S.Department of Energy,Office of Science,Basic Energy Sciences,under Award No.DE-SC0020145Y.Z.would like to acknowledge support for his effort by the Simons Foundation through Grant No.357963 and NSF grant DMS-2142500.
文摘The phase field method is playing an increasingly important role in understanding and predicting morphological evolution in materials and biological systems.Here,we develop a new analytical approach based on the bifurcation analysis to explore the mathematical solution structure of phase field models.Revealing such solution structures not only is of great mathematical interest but also may provide guidance to experimentally or computationally uncover new morphological evolution phenomena in materials undergoing electronic and structural phase transitions.To elucidate the idea,we apply this analytical approach to three representative phase field equations:the Allen-Cahn equation,the Cahn-Hilliard equation,and the Allen-Cahn-Ohta-Kawasaki system.The solution structures of these three phase field equations are also verified numerically by the homotopy continuation method.
基金Project supported by the National Natural Science Foundation of China (Grant No. 12161061)the Fundamental Research Funds for the Inner Mongolia University of Finance and Economics (Grant No. NCYWT23036)+2 种基金the Young Innovative and Entrepreneurial Talents of the Inner Mongolia Grassland Talents Project in 2022,Autonomous Region “Five Major Tasks” Research Special Project for the Inner Mongolia University of Finance and Economics in 2024 (Grant No. NCXWD2422)High Quality Research Achievement Cultivation Fund for the Inner Mongolia University of Finance and Economics in 2024 (Grant No. GZCG2426)the Talent Development Fund of Inner Mongolia Autonomous Region, China。
文摘Under investigation in this paper is a complex modified Korteweg–de Vries(KdV) equation, which describes the propagation of short pulses in optical fibers. Bilinear forms and multi-soliton solutions are obtained through the Hirota method and symbolic computation. Breather-like and bound-state solitons are constructed in which the signs of the imaginary parts of the complex wave numbers and the initial separations of the two parallel solitons are important factors for the interaction patterns. The periodic structures and position-induced phase shift of some solutions are introduced.
基金supported by the National Natural Science Foundation of China (12001033)。
文摘We study the global existence and uniqueness of a strong solution to the kinetic thermomechanical Cucker-Smale(for short,TCS) model coupled with Stokes equations in the whole space.The coupled system consists of the kinetic TCS equation for a particle ensemble and the Stokes equations for a fluid via a drag force.In this paper,we present a complete analysis of the existence of global-in-time strong solutions to the coupled model without any smallness restrictions on the initial data.
文摘According to the second law of thermodynamics, as currently understood, any given transit of a system along the reversible path proceeds with a total entropy change equal to zero. The fact that this condition is also the identifier of thermodynamic equilibrium, makes each and every point along the reversible path a state of equilibrium, and the reversible path, as expressed by a noted thermodynamic author, “a dense succession of equilibrium states”. The difficulties with these notions are plural. The fact, for example, that systems need to be forced out of equilibrium via the expenditure of work, would make any spontaneous reversible process a consumer of work, this in opposition to common thermodynamic wisdom that makes spontaneous reversible processes the most efficient transformers of work-producing-potential into actual work. The solution to this and other related impasses is provided by Dialectical Thermodynamics via its previously proved notion assigning a negative entropy change to the energy upgrading process represented by the transformation of heat into work. The said solution is here exemplified with the ideal-gas phase isomerization of butane into isobutane.
基金This study was supported by grants from the National Natural Science Foundation of China(81972726,82273074 and 82372813)Dawn Project Foundation of Shanghai(21SG36)+2 种基金Shanghai Health Academic Leader Program(2022XD001)the Natural Science Foundation of Shanghai(22ZR1477900)Adjunct Talent Fund of Zhejiang Provincial People’s Hospital(2021-YT).
文摘Background:Cancer-related fatigue(CRF)is a common and debilitating symptom experienced by patients with advanced-stage cancer,especially those undergoing antitumor therapy.This study aimed to evaluate the efficacy and safety of Renshenguben(RSGB)oral solution,a ginseng-based traditional Chinese medicine,in alleviating CRF in patients with advanced hepatocellular carcinoma(HCC)receiving antitumor treatment.Methods:In this prospective,open-label,controlled,multicenter study,patients with advanced HCC at BCLC stage C and a brief fatigue inventory(BFI)score of≥4 were enrolled.Participants were assigned to the RSGB group(RSGB,10 mL twice daily)or the control group(with supportive care).Primary and secondary endpoints were the change in multidimensional fatigue inventory(MFI)score,and BFI and functional assessment of cancer therapy-hepatobiliary(FACT-Hep)scores at weeks 4 and 8 after enrollment.Adverse events(AEs)and toxicities were assessed.Results:A total of 409 participants were enrolled,with 206 assigned to the RSGB group.At week 4,there was a trend towards improvement,but the differences were not statistically significant.At week 8,the RSGB group exhibited a significantly lower MFI score(P<0.05)compared to the control group,indicating improved fatigue levels.Additionally,the RSGB group showed significantly greater decrease in BFI and FACT-Hep scores at week 8(P<0.05).Subgroup analyses among patients receiving various antitumor treatments showed similar results.Multivariate linear regression analyses revealed that the RSGB group experienced a significantly substantial decrease in MFI,BFI,and FACT-Hep scores at week 8.No serious drug-related AEs or toxicities were observed.Conclusions:RSGB oral solution effectively reduced CRF in patients with advanced HCC undergoing antitumor therapy over an eight-week period,with no discernible toxicities.These findings support the potential of RSGB oral solution as an adjunctive treatment for managing CRF in this patient population.
基金financially supported by the National Key Research and Development Program of China(No.2021YFB3803101)the National Natural Science Foundation of China(Nos.52022011,51974028,and 52090041)+1 种基金the Xiaomi Young Scholars ProgramChina National Postdoctoral Program for Innovative Talents(No.BX20230042)。
文摘Solid solution-strengthened copper alloys have the advantages of a simple composition and manufacturing process,high mechanical and electrical comprehensive performances,and low cost;thus,they are widely used in high-speed rail contact wires,electronic component connectors,and other devices.Overcoming the contradiction between low alloying and high performance is an important challenge in the development of solid solution-strengthened copper alloys.Taking the typical solid solution-strengthened alloy Cu-4Zn-1Sn as the research object,we proposed using the element In to replace Zn and Sn to achieve low alloying in this work.Two new alloys,Cu-1.5Zn-1Sn-0.4In and Cu-1.5Zn-0.9Sn-0.6In,were designed and prepared.The total weight percentage content of alloying elements decreased by 43%and 41%,respectively,while the product of ultimate tensile strength(UTS)and electrical conductivity(EC)of the annealed state increased by 14%and 15%.After cold rolling with a 90%reduction,the UTS of the two new alloys reached 576 and 627MPa,respectively,the EC was 44.9%IACS and 42.0%IACS,and the product of UTS and EC(UTS×EC)was 97%and 99%higher than that of the annealed state alloy.The dislocations proliferated greatly in cold-rolled alloys,and the strengthening effects of dislocations reached 332 and 356 MPa,respectively,which is the main reason for the considerable improvement in mechanical properties.
基金support by the NSFC(12071391,12231016)the Guangdong Basic and Applied Basic Research Foundation(2022A1515010860)support by the China Postdoctoral Science Foundation(2023M742401)。
文摘In this paper,we establish some regularity conditions on the density and velocity fields to guarantee the energy conservation of the weak solutions for the three-dimensional compressible nematic liquid crystal flow in the periodic domain.
文摘In this paper,we establish global classical solutions of semilinear wave equations with small compact supported initial data posed on the product space R^(3)×T.The semilinear nonlinearity is assumed to be of the cubic form.The main ingredient here is the establishment of the L^(2)-L^(∞)decay estimates and the energy estimates for the linear problem,which are adapted to the wave equation on the product space.The proof is based on the Fourier mode decomposition of the solution with respect to the periodic direction,the scaling technique,and the combination of the decay estimates and the energy estimates.
基金Project supported by the National Key R&D Program of China (Grant No.2021YFB3501300)the National Natural Science Foundation of China (Grant Nos.91963201 and 12174163)the 111 Project (Grant No.B20063)。
文摘Based on the Landau-Lifshitz-Gilbert(LLG)equation,the precession relaxation of magnetization is studied when the external field H is parallel to the uniaxial anisotropic field H_(k).The evolution of three-component magnetization is solved analytically under the condition of H=nH_(k)(n=3,1 and 0).It is found that with an increase of H or a decrease of the initial polar angle of magnetization,the relaxation time decreases and the angular frequency of magnetization increases.For comparison,the analytical solution for H_(k)=0 is also given.When the magnetization becomes stable,the angular frequency is proportional to the total effective field acting on the magnetization.The analytical solutions are not only conducive to the understanding of the precession relaxation of magnetization,but also can be used as a standard model to test the numerical calculation of LLG equation.
基金supported by the National Natural Science Foundation of China(52071177,52171214)Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX21_1112,KYCX21_1107)+1 种基金Six Talent Peaks Project in Jiangsu Province(2018,XNY-020)the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions。
文摘The hydrogen absorption/desorption kinetic properties of MgH_(2)can be effectively enhanced by doping specific catalysts.In this work,MOFs-derived NiCu@C nanoparticles(~15 nm)with regular core-shell structure were successfully prepared and introduced into MgH_(2)(denoted as MgH_(2)-NiCu@C).The onset and peak temperatures of hydrogen desorption of MgH_(2)-11 wt.%NiCu@C are 175.0℃and282.2℃,respectively.The apparent activation energy of dehydrogenated reaction is 77.2±4.5 kJ/mol for MgH_(2)-11 wt.%NiCu@C,which is lower than half of that of the as-milled MgH_(2).Moreover,MgH_(2)-11 wt.%NiCu@C displays great cyclic stability.The strengthening"hydrogen pumping"effect of reversible solid solutions Mg_(2)Ni(Cu)/Mg_(2)Ni(Cu)H_(4)is proposed to explain the remarkable improvement in hydrogen absorption/desorption kinetic properties of MgH_(2).This work offers a novel perspective for the design of bimetallic nanoparticles and beyond for application in hydrogen storage and other energy related fields.
基金supported by the National Natural Science Foundation of China(No.21776264).
文摘Studying the relationship between ionic interactions and salt solubility in seawater has implications for seawater desalination and mineral extraction.In this paper,a new method of expressing ion-to-ion interaction is proposed by using molecular dynamics simulation,and the relationship between ion-to-ion interaction and salt solubility in a simulated seawater water-salt system is investigated.By analyzing the variation of distance and contact time between ions in an electrolyte solution,from both spatial and temporal perspectives,new parameters were proposed to describe the interaction between ions:interaction distance(ID),and interaction time ratio(ITR).The best correlation between characteristic time ratio and solubility was found for a molar ratio of salt-to-water of 10:100 with a correlation coefficient of 0.96.For the same salt,a positive correlation was found between CTR and the molar ratio of salt and water.For type 1-1,type 2-1,type 1-2,and type 2-2 salts,the correlation coefficients between CTR and solubility were 0.93,0.96,0.92,and 0.98 for a salt-to-water molar ratio of 10:100,respectively.The solubility of multiple salts was predicted by simulations and compared with experimental values,yielding an average relative deviation of 12.4%.The new ion-interaction parameters offer significant advantages in describing strongly correlated and strongly hydrated electrolyte solutions.
基金financially supported by the National Natural Science Foundation of China(Nos.52271034,51974183,and 51974184)Science and Technology Major Project of Yunnan Province(No.202302AB080020)Natural Science Foundation of Shanghai(No.22ZR1425000)。
文摘This study examined the impact of current solution treatment on the microstructure and mechanical properties of the Co-28Cr-6Mo-0.22C alloy investment castings.The findings reveal that the current solution treatment significantly promotes the dissolution of carbides at a lower temperature.The optimal conditions for solution treatment are determined as a solution temperature of 1,125°C and a holding time of 5.0 min.Under these parameters,the size and volume fraction of precipitated phases in the investment castings are measured as6.2μm and 1.1vol.%.The yield strength,ultimate tensile strength,and total elongation of the Co-28Cr-6Mo-0.22C investment castings are 535 MPa,760 MPa,and 12.6%,respectively.These values exceed those obtained with the conventional solution treatment at 1,200°C for 4.0 h.The findings suggest a phase transformation of M_(23)C_(6)→σ+C following the current solution treatment at 1,125°C for 5.0 min.In comparison,the traditional solution treatment at 1,200°C for 4.0 h leads to the formation of M_(23)C_(6)and M_(6)C carbides.It is noteworthy that the non-thermal effect of the current during the solution treatment modifies the free energy of both the matrix and precipitation phase.This modification lowers the phase transition temperature of the M_(23)C_(6)→σ+C reaction,thereby facilitating the dissolution of carbides.As a result,the current solution treatment approach achieves carbide dissolution at a lower temperature and within a significantly shorter time when compared to the traditional solution treatment methods.
基金partially supported by the Science and Technology Research Program of Chongqing Municipal Education Commission(KJQN202100523,KJQN202000536)the National Natural Science Foundation of China(12001074)+3 种基金the Natural Science Foundation of Chongqing(cstc2020jcyj-msxmX0606)supported by the National Natural Science Foundation of Chongqing(CSTB2023NSCQ-MSX0278)the Science and Technology Research Program of Chongqing Municipal Education Commission(KJZD-K202100503)the Research Project of Chongqing Education Commission(CXQT21014)。
文摘In this paper,we are concerned with a three-dimensional non-isothermal model for the compressible nematic liquid crystal flows in a periodic domain.Under some smallness and structural assumptions imposed on the time-periodic force,we establish the existence of the time-periodic solutions to the system by using a regularized approximation scheme and the topological degree theory.We also prove a uniqueness result via energy estimates.